Datasheet

生物描述

特异性	NRCAM Rabbit Recombinant mAb detects endogenous levels of total NRCAM.
背景	NrCAM (neuron-glia-related cell-adhesion molecule) is a transmembrane protein composed of six Ig-like domains and five FnIII repeats in the extracellular region, plus a highly conserved cytoplasmic tail. It is expressed primarily, although not solely, in the nervous system and is involved in neuron-neuron and neuron-glial adhesion as well as directional signaling during axonal cone growth. NrCAM has been shown to be involved in several cellular processes in the central and peripheral nervous systems, including neurite outgrowth, axonal pathfinding and myelination, fasciculation of nerve fibers, and cell migration.

特异性

NRCAM Rabbit Recombinant mAb detects endogenous levels of total NRCAM.

背景

NrCAM (neuron-glia-related cell-adhesion molecule) is a transmembrane protein composed of six Ig-like domains and five FnIII repeats in the extracellular region, plus a highly conserved cytoplasmic tail. It is expressed primarily, although not solely, in the nervous system and is involved in neuron-neuron and neuron-glial adhesion as well as directional signaling during axonal cone growth. NrCAM has been shown to be involved in several cellular processes in the central and peripheral nervous systems, including neurite outgrowth, axonal pathfinding and myelination, fasciculation of nerve fibers, and cell migration.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:500

反应性

Human

MW (kDa)

144kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck