生物描述

特异性

NSE Rabbit Recombinant mAb detects endogenous levels of total NSE.

背景

Enolase 2 (ENO2), also known as neuron-specific enolase (NSE), which includes two enolase isoenzymes, γγ and αγ, is primarily expressed by mature neurons and cells of neuronal origin. ENO2 plays an important role in glycolysis, promoting the conversion of β-glycerophosphate into dihydroxyacetone phosphate. ENO2 has been proposed to act as a pro-survival factor in cancer cells and supports glioblastoma cell adaptation to cellular stresses, such as serum starvation, hypoxia, chemotherapy and radiotherapy. ENO2 expression could be utilized as a gene marker to predict the clinical efficacy of chemotherapy and recurrence.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	47kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Liu CC, et al. Cell Physiol Biochem. 2018, 46(4):1525-1535.

Application Data

WB

IHC