NUP98 Rabbit Recombinant mAb

生物描述

特异性

NUP98 Rabbit Recombinant mAb detects endogenous level of total NUP98.

背景

Nucleoporin 98 (Nup98), a glycine-leucine-phenylalanine-glycine (GLFG) amino acid repeat-containing nucleoporin, plays a critical part in nuclear trafficking. It is an essential component of the nuclear pore complex. It also plays roles in several important biological events such as gene expression, mitotic checkpoint, and pathogenesis. Nup98 is localized to both the cytoplasmic and nuclear sides of the NPC. In vertebrates, Nup98 binds to the cytoplasmic nucleoporin Nup88 in the cytoplasmic side. It also binds to the symmetric nucleoporin Nup96 through the same C-terminal region. Thus, interacting partners of Nup98 can be biased between cytoplasmic and nuclear sides.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human
MW (kDa)	188kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Griffis ER, et al. Mol Biol Cell. 2002, 13(4):1282-97. [2] Iwamoto M, et al. Genes Cells. 2010, 15(7):661-9.

Application Data

WB

IF