p23 Rabbit Recombinant mAb

生物描述

特异性

p23 Rabbit Recombinant mAb detects endogenous level of total p23.

背景

p23 is a small but important cochaperone for the Hsp90 chaperoning pathway. p23 is a ubiquitous and highly conserved protein from yeast to humans, with probable homologs in plants. It appears to facilitate the adenosine triphosphate-driven cycle of Hsp90 binding to client proteins and enters at a late stage of the cycle and enhances the maturation of client proteins. In addition, p23 has Hsp90-independent activities. It possesses an autonomous chaperone activity and has been proposed to act as a recycling factor for steroid receptors following their binding to DNA target sequences. p23 also functions as the cytosolic glutathione-dependent prostaglandin E2 synthase.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	23kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Sara J Felts, et al. Cell Stress Chaperones. 2003, 8(2): 108-113. [2] Iwona Grad, et al. Mol Cell Biol. 2006, 26(23): 8976-8983.

Application Data

WB

IHC