PAK2 Rabbit Recombinant mAb

生物描述

特异性

PAK2 Rabbit Recombinant mAb detects endogenous level of total PAK2.

背景

p21-activated protein kinase (PAK) 2 is a small GTPase-activated serine/threonine kinase activated by the small GTPases CDC42 and Rac, regulates various cytoskeletal functions and is cleaved by caspase-3 during apoptosis. Of the six PAK family members, only PAK2 is ubiquitously expressed and cleaved by caspase-3. It is activated in response to several growth factors like EGF, bFGF and PDGF. PAK2 is also indicated to be involved in neurological disorders like huntington's disease, schizophrenia and cerebral hemorrhage.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	61kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Vilas GL, et al. Proc Natl Acad Sci U S A. 2006, 103(17):6542-7. [2] Varshney P, et al. Mol Cell Endocrinol. 2016, 429:50-61.

Application Data

WB

IHC

IF