PE-Cy7 Mouse CD194/CCR4 Antibody [2G12]

目录号:G1354

打印

生物描述

特异性
背景 小鼠CCR4 cDNA包含1531 bp,编码一个360个氨基酸的蛋白质,与人类CCR4有85%的相似性。CCR4结合CCL17(TARG)和CCL22(MDC)。携带皮肤抗原受体的初始T细胞在皮肤引流淋巴结中被激活,表达皮肤淋巴细胞抗原(CLA),这赋予这些细胞迁移到皮肤中发挥正常效应功能的能力。CCR4和CCR10在小鼠和人类中,对于配体介导的T细胞招募进入皮肤(特别是关于拴系、牢固黏附以及随后的向损伤部位外渗)起重要作用。

使用信息

抗体应用 FCM 推荐用量 0.2 μg ( 1 μL) / million cells in 100 µL volume
反应性 Mouse
抗体类型 Armenian Hamster MW
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining HEK-294F cells transfected with plasmid containing mouse CD194 fragment and fixed/permeabilized with fixation/permeabilization buffer with PE-Cy7 Mouse CD194/CCR4 Antibody (Clone: 2G13) (Product Number: G1354) (green, red is unstained control). Analysis was performed on total cells.