PE Human CD126/IL-6Rα Antibody [UV4]

目录号：H2567

打印

生物描述

特异性
背景 CD126是一种80 kDa的IL-6受体α链，也称为IL-6R。它是免疫球蛋白超家族的成员，在浆细胞、T细胞、活化的B细胞、单核细胞、粒细胞、肝细胞、上皮细胞和成纤维细胞上表达。功能性IL-6受体由CD126和IL-6受体β链（CD130或gp130）的非共价结合形成。CD126以低亲和力结合IL-6但不传递信号。β链（gp130，CD130）本身不结合IL-6，但与α链/IL-6复合物结合以启动信号转导。

使用信息

抗体应用 FCM 推荐用量 5 uL/million cells in 100 µL volume
反应性 Human, African Green, Baboon, Cynomolgus, Rhesus
抗体类型 Mouse MW 80 kDa
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
储存条件
(自收到货起)		 Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining normal human peripheral blood mononuclear cells (PBMCs) with APC CD3 Antibody and PE Human CD162/IL-6Rα Antibody (Clone: UV4) (Product Number: H2567). Analysis was performed on live lymphocytes.