PE Human TCR Vα24-Jα18 Antibody [6B11]

目录号：H3767

打印

生物描述

特异性
背景 TCR Vα24-Jα18由相应的种系配置编码，并在称为恒定NKT（iNKT）细胞的NKT细胞亚群上表达。该TCR与糖脂负载的MHC Ib类分子CD1d相互作用，导致激活和随后的细胞因子产生。iNKT细胞在免疫调节、肿瘤监视和宿主对病原体的应答中发挥作用。尽管它们在血液中的频率较低，但各种趋化因子有助于它们的组织归巢潜力。

使用信息

抗体应用 FCM 推荐用量 5 uL/million cells in 100 µL volume
反应性 Human, Rhesus, Pigtailed Macaque, Sooty Mangabey
抗体类型 Mouse MW
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
储存条件
(自收到货起)		 Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining normal human peripheral blood mononuclear cells (PBMCs) with PE Human TCR Vα24-Jα18 Antibody (Clone: 6B11) (Product Number: H3767), and FITC CD3 Antibody. Analysis was performed on lymphocytes.