Peroxiredoxin 2 Rabbit Recombinant mAb

生物描述

特异性

Peroxiredoxin 2 Rabbit Recombinant mAb detects endogenous level of total Peroxiredoxin 2.

背景

Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the “peroxidatic” Cys (CP) serving as the site of oxidation by peroxides. Prxs can be regulated by changes to phosphorylation, redox and possibly oligomerization states. Prxs are divided into three classes: typical 2-Cys Prxs; atypical 2-Cys Prxs; and 1-Cys Prxs. Although located primarily in the cytosol, Prxs are also found within mitochondria, chloroplasts and peroxisomes, associated with nuclei and membranes, and, in at least one case, exported. The ubiquitous Prxs appear to be diverse in function, ranging from antioxidant enzymes to regulators of signal transduction. Peroxiredoxin 2 (Prx2) is a 2-Cys peroxiredoxin extremely abundant in the erythrocyte and is a key antioxidant enzyme for the erythrocyte.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	22kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Sue Goo Rhee. Mol Cells. 2016, 39(1): 1-5. [2] Wood ZA, et al. Trends Biochem Sci. 2003, 28(1):32-40. [3] Manta B, et al. Arch Biochem Biophys. 2009, 484(2):146-54.

Application Data

WB

IF