生物描述

特异性

Peroxiredoxin 3 Rabbit Recombinant mAb detects endogenous levels of total Peroxiredoxin 3.

背景

Peroxiredoxin 3, a thioredoxin-dependent mitochondrial antioxidant, is a new target for regulating adipocyte function, including adipokine expression, and glucose/lipid metabolism. Prxs are a family of cellular thiol peroxidases scavenging peroxides. Among six distinct members, Prx3 is unique in that it is exclusively localized in the mitochondria. Prx3 is highly expressed in mature adipocytes and decreased in obesity. PRX3 is consistently up-regulated in prostate cancers, over-expressed in greater than 90% of hepatocellular carcinomas, and increases in abundance during malignant progression of cervical cancer.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human
MW (kDa)	26kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Huh JY, et al. Antioxid Redox Signal. 2012, 16(3):229-43. [2] Newick K, et al. PLoS One. 2012, 7(6):e39404.

Application Data

WB

IHC

IF