Pertuzumab (anti-HER2)

目录号：A2008         批次号: A200802

打印

Pertuzumab (anti-HER2)是一种人源单价克隆抗体，抑制HER2二聚化、破坏HER2与其他HER家族成员结合的能力。MW: 148 KD。

抗体信息

CAS号 380610-27-5
配制 100 mM Pro-Ac, 20mM Arg, pH5.0
推荐同型对照 Human IgG1
来源 CHO cells
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
除菌 0.2 μM filtered
纯度 99.17%
蛋白浓度 5.02mg/ml
内毒素 ≤1 EU/mg

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Pertuzumab (anti-HER2)在文献中得到引用

Optical biosensor based on weak value amplification for the high sensitivity detection of Pertuzumab in combination with Trastuzumab binding to the extracellular domain of HER2 [ Optics Express, September 26, 2022, 36839-36848]
An approach to produce thousands of single-chain antibody variants on a SPR biosensor chip for measuring target binding kinetics and for deep characterization of antibody paratopes [ bioRxiv, January 14, 2025, 2025.01.11.632576] PubMed: 39868233
Discovery and preclinical evaluation of monoclonal antibodies and bispecific engagers targeting the NKG2A inhibitory receptor [ Science Advances, February 6, 2026, eadu0690] PubMed: 41637511
XMT-2056, a HER2-Directed STING Agonist Antibody–Drug Conjugate, Induces Innate Antitumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells [ Clinical Cancer Research, 2025, CCR-24-2449] PubMed: 40029253
XMT-2056, a HER2-Directed STING Agonist Antibody-Drug Conjugate, Induces Innate Anti-Tumor Immune Responses by Acting on Cancer Cells and Tumor-Resident Immune Cells [ Clin Cancer Res, 2025, 10.1158/1078-0432.CCR-24-2449] PubMed: 40029253
Development of Fully Human Antibodies Targeting SIRPα and PLA2G7 for Cancer Therapy [ Antibodies (Basel), 2025, 14(1)21] PubMed: 40136470
Characterization of ex vivo expanded natural killer cells for cancer immunotherapy [ Immunol Cell Biol, 2025, 10.1111/imcb.70038] PubMed: 40533418
Development of Fully Human Antibodies Targeting SIRPα and PLA2G7 for Cancer Therapy [ Antibodies, 2025, 21] PubMed: 40136470
Intracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy [ Cell Death Dis, 2024, 15(7):480] PubMed: 38965233
Trastuzumab Potentiates Antitumor Activity of Thiopyrano[2,3-d]Thiazole Derivative in AGS Gastric Cancer Cells [ Molecules, 2024, 29(21)5117] PubMed: 39519758

禁止用于人体及治疗！