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特异性 | PMS2 Rabbit Recombinant mAb detects endogenous level of total PMS2. |
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背景 | PMS2 is an essential component of DNA mismatch repair (MMR) complexes, which play an important role in maintaining genetic stability. MMR functions primarily in the detection and repair of mismatched bases that result from erroneous replication, and also plays important roles in DNA damage response, genetic recombination, control of meiotic progression, and generation of antibody diversity. PMS2 is a latent endonuclease that introduces additional nicks into the discontinuous DNA strand of nicked heteroduplex substrates. |
抗体应用 | WB, IHC, IF,ELISA,ELISA | ||||||
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稀释比例 |
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反应性 | Human | ||||||
MW (kDa) | 110kDa | ||||||
抗体类型 | Rabbit | ||||||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||||||
储存条件 (自收到货起) |
Store at –20°C. |
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WB
Validated by Selleck
IHC
Validated by Selleck
IF
Validated by Selleck