Profilin1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Profilin1 Rabbit Recombinant mAb detects endogenous level of total Profilin1.
背景	Profilins are small actin-binding proteins found in eukaryotes and certain viruses that are involved in cell development, cytokinesis, membrane trafficking, and cell motility. It catalyzes the exchange of ADP/ATP in actin and increases the rate of polymerization. Profilins also interact with polyphosphoinositides (PPI) and proline-rich domains containing proteins. Through its interaction with PPIs, profilin links to signaling pathways between the cell membrane and the cytoskeleton, while its role in membrane trafficking is associated with its interaction with proline-rich domain-containing proteins. Profilin 1 (Pfn1) is a ubiquitously expressed member of the profilin family. It is expressed during all embryonic stages. Profilin1 activity and interactions with other proteins and the corresponding signaling cascades are regulated, in part, by post-translational modifications.

特异性

Profilin1 Rabbit Recombinant mAb detects endogenous level of total Profilin1.

背景

Profilins are small actin-binding proteins found in eukaryotes and certain viruses that are involved in cell development, cytokinesis, membrane trafficking, and cell motility. It catalyzes the exchange of ADP/ATP in actin and increases the rate of polymerization. Profilins also interact with polyphosphoinositides (PPI) and proline-rich domains containing proteins. Through its interaction with PPIs, profilin links to signaling pathways between the cell membrane and the cytoskeleton, while its role in membrane trafficking is associated with its interaction with proline-rich domain-containing proteins. Profilin 1 (Pfn1) is a ubiquitously expressed member of the profilin family. It is expressed during all embryonic stages. Profilin1 activity and interactions with other proteins and the corresponding signaling cascades are regulated, in part, by post-translational modifications.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

15kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck