生物描述

特异性

PSMD4 Rabbit Recombinant mAb detects endogenous levels of total PSMD4

背景

The PSMD4 (aliases Rpn10 or S5a) is a non-ATPase subunit of the 19S regulatory complex capable of binding polyubiquitin chains of four or more ubiquitin molecules during polyubiquitin chain recognition by the 26S proteasome. interference with PSMD4 in any cell type will likely affect the ability of the proteasomal regulatory complex to recognize and bind ubiquitinated proteins. Double mutation of PSMD4 and PSMD8 is lethal in yeast but can be rescued by over-expression of PSMD4.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	50kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Yi YJ, et al. Cell Tissue Res. 2010;341(2):325-40.

Application Data

WB

IF