Datasheet

生物描述

特异性	PSD93 Rabbit Recombinant mAb detects endogenous levels of total PSD93
背景	PSD-93/Chapsyn-110 is a PDZ domain-containing membrane-associated guanylate kinase (MAGUK) that functions as a scaffold to assemble channels, receptors, and other signaling proteins at cell membranes. It contains three PDZ domains, an SH3 domain, and a catalytically inactive guanylate kinase domain, which together mediate protein-protein interactions that are important for channel clustering and the recruitment of signaling complexes for synaptic function. PSD-93 is highly enriched at synapses, but mice lacking this protein have no synaptic structural abnormalities, probably due to overlapping expression and redundancy with other MAGUKs.

特异性

PSD93 Rabbit Recombinant mAb detects endogenous levels of total PSD93

背景

PSD-93/Chapsyn-110 is a PDZ domain-containing membrane-associated guanylate kinase (MAGUK) that functions as a scaffold to assemble channels, receptors, and other signaling proteins at cell membranes. It contains three PDZ domains, an SH3 domain, and a catalytically inactive guanylate kinase domain, which together mediate protein-protein interactions that are important for channel clustering and the recruitment of signaling complexes for synaptic function. PSD-93 is highly enriched at synapses, but mice lacking this protein have no synaptic structural abnormalities, probably due to overlapping expression and redundancy with other MAGUKs.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

110kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck