Recombinant Human Angiopoietin-1(277-498) Fc Protein, BSA (HEK293)

目录号：C0063

Recombinant Human Angiopoietin-1(277-498) Protein is expressed from HEK293 with hFc tag at the N-Terminus. It contains Arg277-Phe498.

生物描述

Accession

NP_001137.2

别名

AGP1 Protein, Human; AGPT Protein, Human; AGPT-1 Protein, Human; ANG1 Protein, Human; HAE5 Protein, Human; KIAA0003 Protein, Human

背景

血管生成素 (ANGPT)-TIE2/TEK 信号通路对血液和淋巴管稳态至关重要。ANGPT1 是 TIE2 的强效激活剂，而 ANGPT2 则作为依赖环境的激动剂/拮抗剂发挥作用。在疾病中，ANGPT2 介导的血管内 TIE2 抑制与血管渗漏、炎症和转移相关。

使用信息

物种

Human

标签

hFc tag at the N-terminus.

来源

HEK293-drived human Angiopoietin-1(277-498) protein Arg277-Phe498.

预测分子量

54 kDa

实际分子量

50-65 kDa, reducing conditions

纯度

>95% as determined by Bis-Tris PAGE.

内毒素

< 0.1 EU/ug by the LAL method

制剂

Lyophilized from 0.22μm filtered solution in PBS with BSA as a carrier protein. Normally 8% trehalose is added as protectant before lyophilization.

复溶方法

开盖前先10,000-12,000 rpm 离心 30 s；向冻干粉中加入无菌PBS，用枪头轻轻吹打混匀，重悬浓度不低于 100 μg/mL；复溶之后分装放-80℃保存，避免反复冻融。

储存条件 (自收到货起)

For long-term storage, keep the product lyophilized at -20°C or below. Please avoid repeated freeze-thaw cycles. Stability: Lyophilized: 12 months (-20°C to -80°C) Reconstituted: 3 months at -80°C under sterile conditions

Data

: Recombinant Human Angiopoietin-1(277-498) Fc Protein (HEK293)on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.