Recombinant Human IL-13 Protein (HEK293)

目录号：C0022

打印

Recombinant Human IL-13 Protein is expressed from HEK293 with His tag at the C-terminus. It contains Gly21-Asn132.

生物描述

Accession

AAK53823

别名

IL13; IL-13; interleukin 13; NC30; P600; ALRH; BHR1; MGC116786; MGC116788; MGC116789

背景

白介素-13 (IL-13) 是一种分子量为 17 kDa 的单体免疫调节细胞因子，在过敏、癌症和组织纤维化的发病机制中起关键作用。它由多种辅助性 T 细胞亚群、自然杀伤细胞、肥大细胞、嗜酸性粒细胞、嗜碱性粒细胞和内脏平滑肌细胞分泌。它抑制炎症细胞因子的产生。与 IL-2 协同调节干扰素-γ 的合成。可能在调节炎症和免疫反应中发挥关键作用。它正向调节巨噬细胞中 IL-31RA 的表达（通过相似性）。

参考文献

使用信息

物种

Human

标签

His tag at the C-terminus.

来源

HEK293-drived human IL-13 protein Gly21-Asn132.

活性

Recombinant Human IL-13 stimulates cell proliferation of the TF-1 human erythroleukemic cell line. The EC50 for this effect is 1.1514 ng/ml.

预测分子量

13.4 kDa

实际分子量

15-35 kDa, reducing conditions

纯度

>95% as determined by Bis-Tris PAGE.

内毒素

< 0.1 EU/ug by the LAL method

制剂

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

储存条件 (自收到货起)

Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data