Recombinant Mouse IL-4 Protein (HEK293)

目录号：C0011

Recombinant Mouse IL-4 Protein is expressed from HEK293 with His tag at the C-terminus. It contains His21-Ser140.

生物描述

Accession

P07750-1

别名

IL4; IL-4; interleukin 4; MGC79402; pitrakinra; B cell growth factor 1; BCDF; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; BSF-1

背景

白细胞介素-4（IL-4）又称IL-13，是一种分泌蛋白，属于IL-4/IL-13家族。IL-4/IL-13具有多种生物学作用，包括刺激活化的B细胞和T细胞增殖。在IL-4和IL-13（Th-2型免疫反应中产生的细胞因子，尤其是在过敏和寄生虫感染期间）存在下，巨噬细胞会被差异性激活，而IL-4和IL-13是白细胞介素-4受体的配体。

参考文献

使用信息

物种

Mouse

标签

His tag at the C-terminus.

来源

HEK293-drived mouse IL-4 protein His21-Ser140.

活性

Recombinant Mouse IL-4 stimulates cell proliferation of the HT-2 cells line. The EC50 for this effect is 0.98 ng/ml. Recombinant Mouse IL-4 stimulates cell proliferation of the MC/9 cells line. The EC50 for this effect is 0.5 ng/ml.

预测分子量

15.4 kDa

实际分子量

17-20 kDa, reducing conditions

纯度

>95% as determined by Bis-Tris PAGE.

内毒素

< 0.1 EU/ug by the LAL method

制剂

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

储存条件 (自收到货起)

Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data