REST/NRSF Rabbit Recombinant mAb Datasheet

生物描述

特异性	REST/NRSF Rabbit Recombinant mAb detects endogenous level of total REST/NRSF.
背景	RE-1 silencing transcription factor (REST), which is also known as neuron-restrictive silencer factor (NRSF), is a transcriptional repressor that regulates gene expression by binding to repressor element 1. REST is known to have a central role in regulating neurogenesis, neural differentiation, and preservation of the unique neural phenotype. REST and its target genes have also been implicated in the pathogenesis and therapeutic mechanism of neurodegenerative diseases, such as schizophrenia, ischemic strokes, Huntington disease, epilepsy, Alzheimer’s disease, Parkinson’s disease, and mood disorders.

特异性

REST/NRSF Rabbit Recombinant mAb detects endogenous level of total REST/NRSF.

背景

RE-1 silencing transcription factor (REST), which is also known as neuron-restrictive silencer factor (NRSF), is a transcriptional repressor that regulates gene expression by binding to repressor element 1. REST is known to have a central role in regulating neurogenesis, neural differentiation, and preservation of the unique neural phenotype. REST and its target genes have also been implicated in the pathogenesis and therapeutic mechanism of neurodegenerative diseases, such as schizophrenia, ischemic strokes, Huntington disease, epilepsy, Alzheimer’s disease, Parkinson’s disease, and mood disorders.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

160kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Jee-Yeon Hwang, et al. Neuropsychopharmacology. 2013, 38(1): 167–182.

Application Data

WB

Validated by Selleck