RUNX1/RUNX2/RUNX3 Rabbit Recombinant mAb Datasheet

生物描述

特异性	RUNX1/RUNX2/RUNX3 Rabbit Recombinant mAb detects endogenous level of total RUNX1/RUNX2/RUNX3.
背景	Runx family transcription factors consist of Runx1, Runx2, and Runx3 that are highly conserved and encode proteins involved in a variety of cell lineages, including blood and blood-related cell lineages, during developmental and adult stages of life. Runx1 is involved in chondrocyte differentiation at an early stage. Runx2 is a major transcription factor for chondrocyte maturation, and Runx3 has a redundant function with Runx2 and it is partly involved in chondrocyte maturation. In mammals, Runx1 was first identified as a critical regulator of hematopoiesis, Runx2 for its role in bone development, and Runx3 for its requirement in neurogenesis. However, all 3 factors were later shown to play critical roles also in other organ systems and it is now known that not only Runx1 but also Runx2 and Runx3 play a part in hematopoiesis.

特异性

RUNX1/RUNX2/RUNX3 Rabbit Recombinant mAb detects endogenous level of total RUNX1/RUNX2/RUNX3.

背景

Runx family transcription factors consist of Runx1, Runx2, and Runx3 that are highly conserved and encode proteins involved in a variety of cell lineages, including blood and blood-related cell lineages, during developmental and adult stages of life. Runx1 is involved in chondrocyte differentiation at an early stage. Runx2 is a major transcription factor for chondrocyte maturation, and Runx3 has a redundant function with Runx2 and it is partly involved in chondrocyte maturation. In mammals, Runx1 was first identified as a critical regulator of hematopoiesis, Runx2 for its role in bone development, and Runx3 for its requirement in neurogenesis. However, all 3 factors were later shown to play critical roles also in other organ systems and it is now known that not only Runx1 but also Runx2 and Runx3 play a part in hematopoiesis.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

51kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck