RUNX2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	RUNX2 Rabbit Recombinant mAb detects endogenous level of total RUNX2.
背景	Runx transcription factors contribute to regulatory mechanisms that are operative throughout osteoblast differentiation and are required to modulate expression of target genes at key developmental transitions. Runx2 is principally linked to osteoblast proliferation and differentiation and is obligatory for regulation of skeletal genes, hypertrophic chondrocytes as well as endochondral and intramembraneous bone formation and skeletal development. Runx2 is the principal osteogenic master switch and additionally involved in differentiation of nonosseous tissues. Runx2 also regulates cell migration and vascular invasion in bone.

特异性

RUNX2 Rabbit Recombinant mAb detects endogenous level of total RUNX2.

背景

Runx transcription factors contribute to regulatory mechanisms that are operative throughout osteoblast differentiation and are required to modulate expression of target genes at key developmental transitions. Runx2 is principally linked to osteoblast proliferation and differentiation and is obligatory for regulation of skeletal genes, hypertrophic chondrocytes as well as endochondral and intramembraneous bone formation and skeletal development. Runx2 is the principal osteogenic master switch and additionally involved in differentiation of nonosseous tissues. Runx2 also regulates cell migration and vascular invasion in bone.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

56kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck