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特异性 | SNAP23 Rabbit Recombinant mAb detects endogenous level of total SNAP23. |
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背景 | Members of the SNARE-family of proteins are known to be key regulators of the membrane-membrane fusion events required for intracellular membrane traffic. The ubiquitously expressed SNARE protein SNAP-23 regulates a wide variety of exocytosis events. The SNARE proteins on the target membranes for vesicles are termed t-SNAREs. SNAP-23 is a kind of t-SNAREs and a cellular homologueof SNAP-25. In most cells, it serves as the t-SNARE protein taking part in the formation of SNARE complexes which precedes membrane fusion and exocytosis. While SNAP-25 protein signal was weak in the cytoplasm and strong in the plasma membrane, SNAP-23, on the other hand, was distributed in the cytoplasm and in the plasma membrane region. |
抗体应用 | WB ,ELISA,ELISA | ||
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稀释比例 |
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反应性 | Human Mouse Rat | ||
MW (kDa) | 23kDa | ||
抗体类型 | Rabbit | ||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||
储存条件 (自收到货起) |
Store at –20°C. |
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WB
Validated by Selleck