SUMO1 Rabbit Recombinant mAb

生物描述

特异性

SUMO1 Rabbit Recombinant mAb detects endogenous level of total SUMO1.

背景

Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking, and signal transduction are subject to reversible sumoylation. SUMO proteins belong to a small family of protein modifiers, the ubiquitin-like proteins (Ubls), which are characterized by the ubiquitin fold (globular β-grasp fold) and a characteristic C-terminal Gly-Gly motif that is exposed after proteolytic maturation. In mammalian cells, SUMO1 exists predominantly in the conjugated form, whereas SUMO2/3 is detected predominantly in its unconjugated form.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	12kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Flotho A, et al. Annu Rev Biochem. 2013, 82:357-85.

Application Data

WB

IHC

IF