SUMO4 Rabbit Recombinant mAb Datasheet

生物描述

特异性	SUMO4 Rabbit Recombinant mAb detects endogenous level of total SUMO4.
背景	Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking, and signal transduction are subject to reversible sumoylation. SUMO proteins belong to a small family of protein modifiers, the ubiquitin-like proteins (Ubls), which are characterized by the ubiquitin fold (globular β-grasp fold) and a characteristic C-terminal Gly-Gly motif that is exposed after proteolytic maturation.

特异性

SUMO4 Rabbit Recombinant mAb detects endogenous level of total SUMO4.

背景

Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking, and signal transduction are subject to reversible sumoylation. SUMO proteins belong to a small family of protein modifiers, the ubiquitin-like proteins (Ubls), which are characterized by the ubiquitin fold (globular β-grasp fold) and a characteristic C-terminal Gly-Gly motif that is exposed after proteolytic maturation.

使用信息

抗体应用

WB, IF,ELISA,ELISA

稀释比例

WB	IF
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

15kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Flotho A, et al. Annu Rev Biochem. 2013, 82:357-85.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck