TAK1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	TAK1 Rabbit Recombinant mAb detects endogenous level of total TAK1.
背景	Transforming growth factor β-activated kinase 1 (TAK1, also called MAP3K7) is a key regulator of the innate immunity and the proinflammatory signaling pathway. In response to interleukin-1, tumornecrosis factor-α, and toll-like receptor agonists, it mediates the activation of the nuclear factor κB (NF-κB), c-Jun N-terminal kinase (JNK), and p38 pathways. In addition, TAK1 plays a central role in adaptive immunity, in which it mediates signaling from T- and B-cell receptors.

特异性

TAK1 Rabbit Recombinant mAb detects endogenous level of total TAK1.

背景

Transforming growth factor β-activated kinase 1 (TAK1, also called MAP3K7) is a key regulator of the innate immunity and the proinflammatory signaling pathway. In response to interleukin-1, tumornecrosis factor-α, and toll-like receptor agonists, it mediates the activation of the nuclear factor κB (NF-κB), c-Jun N-terminal kinase (JNK), and p38 pathways. In addition, TAK1 plays a central role in adaptive immunity, in which it mediates signaling from T- and B-cell receptors.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

75kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Dai L, et al. IUBMB Life. 2012, 64(10):825-34.

Application Data

WB

Validated by Selleck