TBHQ

目录号：S4990 批次号：S499006

化学数据

	别名	Tert-butylhydroquinone	储存条件 (自收到货起)	3年 / -20°C / 粉状 1年 / -80°C / 溶于溶剂
	化学式	C₁₀H₁₄O₂
	分子量	166.22	CAS号	1948-33-0
Solubility (25°C)*	体外	DMSO	33 mg/mL (198.53 mM)
		Ethanol	33 mg/mL (198.53 mM)
		Water	4 mg/mL (24.06 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述

Tert-butylhydroquinone (TBHQ)是一种抗氧化剂，用于阻止脂质过氧化，具有多种细胞保护作用。同时，它也是Nrf2的激活剂。

靶点

Nrf2 ^[1]

参考文献

TBHQ在文献中得到引用

Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway [ Mol Med, 2025, 31(1):1]	PubMed: 39754066
Inhibition of insulin degrading enzyme suppresses osteoclast hyperactivity via enhancing Nrf2-dependent antioxidant response in glucocorticoid-induced osteonecrosis of the femoral head [ Mol Med, 2024, 30(1):111]	PubMed: 39085816
BATF is involved in the malignant phenotype and epithelial-mesenchymal transition of colon cancer cells via ERK/PD-L1 signaling [ Histol Histopathol, 2024, 27:18823]	PubMed: 39439410
DDRGK1 Enhances Osteosarcoma Chemoresistance via Inhibiting KEAP1-Mediated NRF2 Ubiquitination [ Adv Sci (Weinh), 2023, 10(14):e2204438]	PubMed: 36965071
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity [ Adv Sci (Weinh), 2023, 10(3):e2203718]	PubMed: 36445063
Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction [ Free Radic Biol Med, 2023, 202:35-45]	PubMed: 36963639
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage [ Biomaterials, 2022, 288:121742]	PubMed: 36030105
AADAC protects colorectal cancer liver colonization from ferroptosis through SLC7A11-dependent inhibition of lipid peroxidation [ J Exp Clin Cancer Res, 2022, 41(1):284]	PubMed: 36163032
Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation [ Free Radic Biol Med, 2022, 180:220-235]	PubMed: 35074488
Vitamin D3 protects against nitrogen mustard-induced apoptosis of the bronchial epithelial cells via activating the VDR/Nrf2/Sirt3 pathway [ Toxicol Lett, 2022, 354:14-23]	PubMed: 34757179

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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