Thymidine Kinase 1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Thymidine Kinase 1 Rabbit Recombinant mAb detects endogenous level of total Thymidine Kinase 1.
背景	Thymidine Kinase is a pyrimidine salvage pathway enzyme involved in DNA synthesis and repair. In the presence of adenosine triphosphate, TK catalyzes the conversion of thymidine to thymidine monophosphate (dTMP), dTMP is subsequently phosphorylated to its triphosphate analog (dTTP) by TK. TK is present in human cells in two major forms, TK1 and TK2. In the salvage pathway, thymidine kinases (TKs), TK1 in cytosol and TK2 in mitochondria, are responsible for dTMP production from thymidine.

特异性

Thymidine Kinase 1 Rabbit Recombinant mAb detects endogenous level of total Thymidine Kinase 1.

背景

Thymidine Kinase is a pyrimidine salvage pathway enzyme involved in DNA synthesis and repair. In the presence of adenosine triphosphate, TK catalyzes the conversion of thymidine to thymidine monophosphate (dTMP), dTMP is subsequently phosphorylated to its triphosphate analog (dTTP) by TK. TK is present in human cells in two major forms, TK1 and TK2. In the salvage pathway, thymidine kinases (TKs), TK1 in cytosol and TK2 in mitochondria, are responsible for dTMP production from thymidine.

使用信息

抗体应用

WB, IHC, IF,ELISA,ELISA

稀释比例

WB	IHC	IF
1:1000	1:50	1:50

反应性

Human

MW (kDa)

25kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck

IF

Validated by Selleck