Tiragolumab (anti-TIGIT)

目录号：A2028         批次号: A202802

打印

Tiragolumab (anti-TIGIT) (RG6058, MTIG7192A) 是一种人源化 IgG1/kappa 单克隆抗体，可与 TIGIT 结合以防止其与其配体 PVR (CD155) 相互作用。

抗体信息

CAS号 1918185-84-8
推荐同型对照 Human IgG1, κ
来源 CHO cells
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
除菌 0.2 μM filtered
纯度 99.86%
蛋白浓度 5 mg/ml
内毒素 <1 EU/mg

Tiragolumab (anti-TIGIT)在文献中得到引用

The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8 + T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR signaling [ Cell Commun Signal, 2024, 22(1):35] PubMed: 38216949
Knockout of the inhibitory receptor TIGIT enhances the antitumor response of ex vivo expanded NK cells and prevents fratricide with therapeutic Fc-active TIGIT antibodies [ J Immunother Cancer, 2023, 11(12)e007502] PubMed: 38081778

禁止用于人体及治疗！