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目录号:A2007 批次号: A200706
Trastuzumab (anti-HER2)曲妥珠单抗是人源重组的抗体抑制剂,与HER2的胞外区域相结合。 MW:145.53 KD。
CAS号 | 180288-69-1 |
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配制 | PBS buffer, pH 7.2 |
推荐同型对照 | Human IgG1 |
来源 | CHO cells |
储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
纯度 | 99.84% |
蛋白浓度 | 3.27 mg/ml |
内毒素 | <1 EU/mg |
Identification of a novel potent CDK inhibitor degrading cyclinK with a superb activity to reverse trastuzumab-resistance in HER2-positive breast cancer in vivo [ Eur J Med Chem, 2024, 264:116014] | PubMed: 38061230 |
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression [ Int J Biol Sci, 2023, 19(2):377-392] | PubMed: 36632463 |
Irreversible HER2 inhibitors overcome resistance to the RSL3 ferroptosis inducer in non-HER2 amplified luminal breast cancer [ Cell Death Dis, 2023, 14(8):532] | PubMed: 37596261 |
Detecting Disruption of HER2 Membrane Protein Organization in Cell Membranes with Nanoscale Precision [ ACS Sens, 2023, 10.1021/acssensors.3c01437] | PubMed: 37955934 |
T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity [ Cell Rep, 2023, 42(7):112797] | PubMed: 37436890 |
Engineering choroid plexus-on-a-chip with oscillatory flow for modeling brain metastasis [ Mater Today Bio, 2023, 22:100773] | PubMed: 37664794 |
Multi-Targeting Anticancer Activity of a New 4-Thiazolidinone Derivative with Anti-HER2 Antibodies in Human AGS Gastric Cancer Cells [ Int J Mol Sci, 2023, 24(7)6791] | PubMed: 37047765 |
The effect of the alpha-specific PI3K inhibitor alpelisib combined with anti-HER2 therapy in HER2+/PIK3CA mutant breast cancer [ Front Oncol, 2023, 13:1108242] | PubMed: 37469415 |
Immune suppressive signaling regulated by latent transforming growth factor beta binding protein 1 promotes metastasis in cervical cancer [ Braz J Med Biol Res, 2023, 55:e12206] | PubMed: 36629522 |
Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer [ Adv Sci (Weinh), 2022, e2204211] | PubMed: 36373729 |
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