Urolithin A

目录号：S5312 批次号：S531201

化学数据

	别名	3,8-Dihydroxy Urolithin; 2',7-Dihydroxy-3,4-benzocoumarin	储存条件 (自收到货起)	3年 / -20°C / 粉状 1年 / -80°C / 溶于溶剂
	化学式	C₁₃H₈O₄
	分子量	228.20	CAS号	1143-70-0
Solubility (25°C)*	体外	DMSO	45 mg/mL (197.19 mM)
		Water	Insoluble
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述	Urolithin A (3,8-Dihydroxy Urolithin, 2',7-Dihydroxy-3,4-benzocoumarin), 是鞣花酸的代谢产物，是一种首创的天然化合物，口服后可在体外和体内诱导线粒体自噬。

参考文献

Urolithin A在文献中得到引用

Neuron-targeted overexpression of caveolin-1 alleviates diabetes-associated cognitive dysfunction via regulating mitochondrial fission-mitophagy axis [ Cell Commun Signal, 2023, 21(1):357]	PubMed: 38102662
Urolithin A's Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats [ Biomedicines, 2023, 11(4), 1125]	PubMed: 37189743
Urolithin A's Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats [ Biomedicines, 2023, 11(4)1125]	PubMed: 37189743
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice [ Neural Regen Res, 2022, 17(9):2007-2013]	PubMed: 35142690
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway [ Food Funct, 2022, 13(1):375-385]	PubMed: 34905594
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2 [ Bioengineered, 2022, 13(3):5064-5078]	PubMed: 35164658
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model [ Neuropharmacology, 2022, 207:108963]	PubMed: 35065082
PINK1-mediated mitophagy reduced inflammatory responses to Porphyromonas gingivalis in macrophages [ Oral Dis, 2022, 10.1111/odi.14286]	PubMed: 35730318
Disruption of innate defense responses by endoglycosidase HPSE promotes cell survival [ JCI Insight, 2021, 6(7)144255]	PubMed: 33621216
Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection [ Neuropharmacology, 2021, 196:108360]	PubMed: 33122030

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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