VE Cadherin Rabbit Recombinant mAb Datasheet

生物描述

特异性	VE Cadherin Rabbit Recombinant mAb detects endogenous level of total VE Cadherin.
背景	VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key role in the maintenance of vascular integrity. During embryo development, VE-cadherin is required for the organization of a stable vascular system, and in the adult it controls vascular permeability and inhibits unrestrained vascular growth. The mechanisms of action of VE-cadherin are complex and include reshaping and organization of the endothelial cell cytoskeleton and modulation of gene transcription. It is usually used as a cell-specific marker of endothelial cells during the development of the embryo vasculature and embryonic stem cell differentiation to endothelial cells in vitro.

特异性

VE Cadherin Rabbit Recombinant mAb detects endogenous level of total VE Cadherin.

背景

VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key role in the maintenance of vascular integrity. During embryo development, VE-cadherin is required for the organization of a stable vascular system, and in the adult it controls vascular permeability and inhibits unrestrained vascular growth. The mechanisms of action of VE-cadherin are complex and include reshaping and organization of the endothelial cell cytoskeleton and modulation of gene transcription. It is usually used as a cell-specific marker of endothelial cells during the development of the embryo vasculature and embryonic stem cell differentiation to endothelial cells in vitro.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Mouse

MW (kDa)

90,125kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Giannotta M, et al. Dev Cell. 2013, 26(5):441-54.

Application Data

WB

Validated by Selleck