WASL Rabbit Recombinant mAb Datasheet

生物描述

特异性	WASL Rabbit Recombinant mAb detects endogenous level of total WASL.
背景	WASL (Wiskott-Aldrich Syndrome Like) proteins are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The WASL is a homolog of WAS protein, which is a hematopoietic specific regulator of actin nucleation in response to signals arising at the cell membrane. unlike the WASP (WAS protein), WASL is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

特异性

WASL Rabbit Recombinant mAb detects endogenous level of total WASL.

背景

WASL (Wiskott-Aldrich Syndrome Like) proteins are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The WASL is a homolog of WAS protein, which is a hematopoietic specific regulator of actin nucleation in response to signals arising at the cell membrane. unlike the WASP (WAS protein), WASL is ubiquitously expressed and shows highest expression in neural tissues. It has been shown to bind Cdc42 directly, and induce formation of long actin microspikes.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse

MW (kDa)

55kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Bosticardo M1, et al. Blood. 2009, 113(25):6288-95.

Application Data

WB

Validated by Selleck