YB1 Rabbit Recombinant mAb

生物描述

特异性

YB1 Rabbit Recombinant mAb detects endogenous level of total YB1.

背景

The multifunctional vertebrate Y-box-binding protein 1 (YB-1) is a member of a large family of proteins with an evolutionally ancient cold shock domain. This protein is involved in a number of cellular processes including proliferation, differentiation, and stress response. The YB 1 protein performs its functions both in the cytoplasm and in the cell nucleus. It can also be secreted from cells and by binding to the receptors on their surface it can activate intracellular signaling. YB-1 is a DNA- and RNA-binding protein that has properties of a nucleic acid chaperone, and it interacts with a great variety of other proteins. By binding to nucleic acids, YB-1 is involved in almost all DNA- and mRNA-dependent processes including DNA replication and repair, transcription, pre mRNA splicing, and mRNA translation. It packs and stabilizes mRNAs as well as realizes global and specific regulation of gene expression at different levels.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	50kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Eliseeva IA, et al. Biochemistry (Mosc). 2011, 76(13):1402-33. [2] Lasham A, et al. J Biol Chem. 2003, 278(37):35516-23.

Application Data

WB

IHC

IF