ZINC00881524 (ROCK inhibitor)

目录号:S8448 批次号:S844802

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化学数据

化学结构式 别名 N/A 储存条件
(自收到货起)
3年 / -20°C / 粉状
1年 / -80°C / 溶于溶剂
化学式

C21H20N2O3S

分子量 380.46 CAS号 557782-81-7
Solubility (25°C)* 体外 DMSO 76 mg/mL (199.75 mM)
Ethanol 15 mg/mL (39.42 mM)
Water Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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生物活性

产品描述 ZINC00881524是ROCK抑制剂。

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

ZINC00881524 (ROCK inhibitor)在文献中得到引用

Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes [ bioRxiv, 2023, 2023.06.07.544100] PubMed: 37333144
A non-coding GWAS variant impacts anthracycline-induced cardiotoxic phenotypes in human iPSC-derived cardiomyocytes [ Nat Commun, 2022, 13(1):7171] PubMed: 36418322
Development of novel aptamer-based targeted chemotherapy for bladder cancer [ Cancer Res, 2022, canres.2691.2021] PubMed: 35064018
Telomere shortening impairs alveolar regeneration [ Cell Prolif, 2022, e13211] PubMed: 35274784
Biphasic cell cycle defect causes impaired neurogenesis in down syndrome [ Front Genet, 2022, 13:1007519] PubMed: 36313423
Extracellular Matrix in Synthetic Hydrogel-based Prostate Cancer Organoids Regulate Therapeutic Response to EZH2 and DRD2 inhibitors [ Adv Mater, 2021, e2100096] PubMed: 34676924
Bioinspired 3D Culture in Nanoliter Hyaluronic Acid-Rich Core-Shell Hydrogel Microcapsules Isolates Highly Pluripotent Human iPSCs [ Small, 2021, e2102219] PubMed: 34260817
Upregulation of HOXC9 generates interferon-gamma resistance in gastric cancer by inhibiting the DAPK1/RIG1/STAT1 axis [ Cancer Sci, 2021, 112(9):3455-3468] PubMed: 34159686
The Role of Small Molecules and Their Effect on the Molecular Mechanisms of Early Retinal Organoid Development [ Int J Mol Sci, 2021, 22(13)7081] PubMed: 34209272
Single-Cell Atlas Reveals Fatty Acid Metabolites Regulate the Functional Heterogeneity of Mesenchymal Stem Cells [ Front Cell Dev Biol, 2021, 9:653308] PubMed: 33912565

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品,在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同,大多数建议储存在-20°C,抑制剂属于化学试剂,可在常温下运输储存两周左右。即使如此,我们保证产品的出货量将保持产品质量的条件下,一般都会放入冰袋。望阁下收到产品后,请按照产品数据表建议适当存储。

如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!

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