Decarboxylase

  • 抑制剂选择性比较
  • 溶解性比较
目录号 产品目录 溶解度(25°C)
DMSO 酒精
S1891 Carbidopa <1 mg/mL 4 mg/mL <1 mg/mL
S2453 Benserazide HCl 58 mg/mL 58 mg/mL 1 mg/mL
S1642 Methyldopa <1 mg/mL 2 mg/mL <1 mg/mL
S4582 Eflornithine hydrochloride hydrate 47 mg/mL <1 mg/mL <1 mg/mL
S5448 S(-)-Carbidopa <1 mg/mL 0.01 mg/mL <1 mg/mL
S5444 4-Bromo-3-hydroxybenzoic acid -1 mg/mL 43 mg/mL -1 mg/mL
产品目录 产品描述 文献引用 实验数据
S1891

Carbidopa

Carbidopa 是一种芳香族-L-氨基酸脱羧酶抑制剂,IC50为29±2 μM。

S2453

Benserazide HCl

Benserazide HCl是一种外周性的芳香族L-氨基酸脱羧酶(AAAD)或DOPA脱羧酶抑制剂。

S1642

Methyldopa

Methyldopa 是DOPA 脱羧酶竞争性抑制剂,ED50为21.8 mg/kg。

S4582

Eflornithine hydrochloride hydrate

Eflornithine(Difluoromethylornithine)通过对鸟氨酸脱羧酶的不可逆抑制作用,抑制多胺生物合成。它是一种化疗保护剂,可阻止血管生成。其生物半衰期为8小时。

S5448New

S(-)-Carbidopa

S(-)-Carbidopa is a peripheral decarboxylase inhibitor, used in combination with levodopa for treatment of Parkinsonism.

S5444New

4-Bromo-3-hydroxybenzoic acid

4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals.

Tags: Decarboxylase inhibition | Decarboxylase pathway | Decarboxylase activation | Decarboxylase inhibitor review