HBG1/2 Rabbit Recombinant mAb
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使用信息
| 抗体应用 | wb,ELISA | ||
|---|---|---|---|
| 稀释比例 |
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| 反应性 | Human | ||
| MW (kDa) | 12kDa | ||
| 抗体类型 | Rabbit | ||
| 浓度 | 1mg/ml | ||
| 储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||
| 储存条件 (自收到货起) |
Store at –20°C. |
生物描述
| 特异性 | HBG1/2 Rabbit Recombinant mAb detects endogenous levels of total HBG1/2. |
|---|---|
| 背景 | The β-globin gene cluster of mammals contains a set of developmentally regulated genes that are arranged in their temporal order of expression. The ε-, γ-, and η-globin genes (HBE, HBG, and HBH, respectively) are expressed in embryonic erythroid cells and are descended from an ancestral HBE gene. The δ- and β-globin genes (HBD and HBB, respectively) are expressed in fetal and adult erythroid cells and are descended from an ancestral HBB gene. The γ-globin genes (HBG1 and HBG2) are active during fetal growth and are normally expressed in the fetal liver, spleen and bone marrow. The combination of two γ-globin chains and two α-globin chains forms fetal haemoglobin (HbF), which is the main oxygen transport protein in the human fetus. |
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