• H-ras
  • N-ras
  • K-ras
  • Ral

H-ras 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S8303 Kobe0065 Kobe0065 is an H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM. Selective
S2797 Lonafarnib (SCH66336) Lonafarnib (SCH66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM in cell-free assays, respectively. Phase 3. Pan H-ras, IC50: 1.9 nM
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