• TET
  • DNMT1
  • DNMT3

TET 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S6682 Bobcat339 hydrochloride Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe. Selective TET1, IC50: 33 μM; TET2, IC50: 73 μM
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