• p110α
  • p110β
  • p110δ
  • p110γ
  • C2β
  • Vps34

C2β 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S7103 Taselisib (GDC 0032) Taselisib (GDC 0032, RG7604) is a potent, next-generation β isoform-sparing PI3K inhibitor targeting PI3Kα/δ/γ with Ki of 0.29 nM/0.12 nM/0.97nM, >10 fold selective over PI3Kβ. Pan C2β, IC50: 292 nM
S2636 A66 A66 is a potent and specific p110α inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity for p110α over other class-I PI3K isoforms. Pan C2β, IC50: 462 nM
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