Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 M3LwcWZ2dmO2aX;uJGF{e2G7 Mn;iNVAh|ryP NEnGcGI3KGh? NV;CO5g2cW6lcnXhd4V{KHCqb4PwbI9zgWyjdHnvckBw\iCxdnXy[ZhxemW|c3XkJGtNUEx|IHH0JHM1OzN? NWTKc3E4OjZ2M{W0PVg>
Mo-DCs MlzRSpVv[3Srb36gRZN{[Xl? NWnwXpZMPTBizszN NV7UTlQxOjUkgJno MmDZdJJwdW:2ZYOgTWwuOjNicILv[JVkfGmxbjDpckB1cGVic4Xw[ZJv[XSjboSgc4Yhgnmvb4PhckB{fGmvdXzheIVlKE2xLVTDd:Kh M1jZWFI3PDF{OUS4
RBMECs  MXzGeY5kfGmxbjDBd5NigQ>? MknWOeKh|ryP Mn3rNeKhcA>? MmXlZoxw[2u|IITo[UBT[WNzIHnuZYN1cX[jdHnvckBqdmS3Y3XkJIJ6KEWPQWCtTWk> MoLYNlY{PThyM{m=
INA-6 MXzD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MlLyNE0yODBizszN NUPOPGREPzMkgJno NUTBO5FlcW6mdXPld{Bk\WyuIHTlZZRpKGSxc3Wg[IVx\W6mZX70cJk> MXSyOlMxPjZ{NB?=
OPM-2 MVfD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MlewNE0yODBizszN NGnwV2I4OuLCiXi= M4PLWIlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 NUjuZ3J6OjZ|ME[2NlQ>
U266 NHHRWGlE\WyuIG\pZYJqdGm2eTDBd5NigQ>? M2HtW|AuOTByIN88US=> NHvpPYk4OuLCiXi= NEnyfGhqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> M13pWFI3OzB4NkK0
H929 NVTVU2RSS2WubDDWbYFjcWyrdImgRZN{[Xl? M1TYTlAuOTByIN88US=> NVnubG9RPzMkgJno MV3pcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= MlTyNlY{ODZ4MkS=
RPMI 8226 NXjTd3dmS2WubDDWbYFjcWyrdImgRZN{[Xl? NYTqUXpHOC1zMECg{txO NHXvVXM4OuLCiXi= NWnvO4JrcW6mdXPld{Bk\WyuIHTlZZRpKGSxc3Wg[IVx\W6mZX70cJk> NXywUHA{OjZ|ME[2NlQ>
MDCK  Mkf4SpVv[3Srb36gRZN{[Xl? NGjTUG0yOCEEtV2= M1zId|I1KGh? NHGzOYdFVVOR MWP1dJJm\3WuYYTld{B1cGViZYjwdoV{e2mxbjDv[kBVT0ZvzsKxJIFv\CCFVFfGxsA> M2jhVFI3OjB{M{Wy
MDCK  M3nWR2Z2dmO2aX;uJGF{e2G7 NVfOSIRWOTBiwsXN NIXB[4ozPCCq M1PkOWROW09? NYTTOVhucW6qaXLpeJMhfGinIHnuZ5Jm[XOnZDDlfJBz\XO|aX;uJI9nKE[QIHPheZNm\CCkeTDUS2Yu|rJz M4rnSlI3OjB{M{Wy
Spinal cords  MWrGeY5kfGmxbjDBd5NigQ>? MXixxsDPxE1? NFLCPJY{OCCvaX6= MV\zeIlufWyjdHXzJINCVVBibHX2[Yx{ MnG3NlYyOjZ7Mk[=
BeWo  Ml3SSpVv[3Srb36gRZN{[Xl? NWPMWVNEOjYkgJpOwG0> NYPBcXhuOjRxNEivO|IhcA>? M{fiOoxm[WS|IITvJIFvKGmwY4LlZZNmKGmwIITo[UBmgHC{ZYPzbY9vKG:oIH;0bIVzKG[3c3nvckBu[XKtZYLz MljXNlYxPTN3NEm=
bovine oocytes MUPGeY5kfGmxbjDBd5NigQ>? MV6xNFDDqM7:TR?= NIDXOXkyOsLiaB?= M3vBc4lvcGmkaYTzJJRp\SCnZn\lZ5Qhd2ZiTmDQRUBidmRxb4KgUnBRSyC2bzDzeIlufWyjdHWgdoV{fW2ydHnvckBw\iCvZXnvd4l{ MX[yOlA2OTZzMR?=
Caco-2  M1XudGZ2dmO2aX;uJGF{e2G7 MlfqNE4yNzFxMUCg{txO M4\5cVIxyqCvaX6= MXvpcoR2[2W|IHGg[I9{\S2mZYDlcoRmdnRiaX7jdoVie2ViaX6gbY51emGlZXzseYxieiClQV3QJIxmfmWucx?= NXzURWJnOjZyNEmxNFI>
Caco-2  NFuySHRHfW6ldHnvckBCe3OjeR?= MoXpNE4yNzFxMUCg{txO MWCyOEBp MoXwbY5kemWjc3XzJG1TWDJicILveIVqdiCuZY\lcC=> M1PzSVI3ODR7MUCy
AML-12  M3HXWWZ2dmO2aX;uJGF{e2G7 NXPrTmpROjBizszN NYT4OnJMOyCq M3TrW5VxemWpdXzheIV{KHSqZTDwbI9{eGixconsZZRqd25ibHX2[Yx{KGG2IGTodk01OTFiYX7kJHNmei12OUO= NHOxN3EzPjB2OEm4OS=>
AML-12  MYnGeY5kfGmxbjDBd5NigQ>? NHrHcGUzOCEQvF2= NY[wUHhPOS16IHi= MVfpcoNz\WG|ZYOg[4x2[2:|ZTDwdo9lfWO2aX;u NVvpOpZCOjZyNEi5PFU>
AML-12  NXfkUmF5TnWwY4Tpc44hSXO|YYm= NUXPeFlTOjBizszN M{TxNFMhcA>? M3;MSZVxNXKnZ4XsZZRme8LiUHfjNYEtyqCSZYDjb{wh[W6mwrDHOpBkyqCvUl7BJIxmfmWucx?= NYrJW5BmOjZyNEi5PFU>
AML-12  MWLGeY5kfGmxbjDBd5NigQ>? MVSyNEDPxE1? MYWzJIg> NG\1ZoVqdmS3Y3XzJJRp\SCmZYDoc5NxcG:{eXzheIlwdiCxZjDDVnREOsLi MUGyOlA1QDl6NR?=
RBMECs NVfTbWpyTnWwY4Tpc44hSXO|YYm= M2DlbVXDqM7:TR?= MonXNUBp NEnvRWxqdmirYnn0d{BGVUGSLVnJMYlv\HWlZXSgbY5i[3SrdnH0bY9vKG:oIGLhdFHDqA>? NX3iN3NGOjZyNES2OlM>
EndoC-βH1 MUfGeY5kfGmxbjDBd5NigQ>? NGrFWJk2yqEQvF2= NEeybXgyKGh? NYrvXJlueG:2ZX70bYF1\XNiZ3z1Z49{\S2rbnT1Z4VlKGmwc4XsbY4he2WlcnX0bY9vKGmwIITo[UBxemW|ZX7j[UBw\iCpbIXjc5Nm M{PxRlI3ODJ6NU[y
EndoC-βH1 MlG4SpVv[3Srb36gRZN{[Xl? MV:1xsDPxE1? NVPXPZFoOSCq MYfs[YFleyC2bzDhJJN1em:wZzDjRW1RKGmwY4LlZZNm NGf3bmIzPjB{OEW2Ni=>
SH-SY5Y MnHlSpVv[3Srb36gRZN{[Xl? MnzpN|Ah|ryP NYPmZZZCOzBibXnu NYnSO4c4TE2VTx?= NFn3SI5{cWewaX\pZ4FvfGy7IHnuZ5Jm[XOnczD0bIUh[WO2aY\heIlwdiCxZjDQT2E> Ml;ENlYxOjVzM{e=
PC-3 NXfsTo53TnWwY4Tpc44hSXO|YYm= MknhOFAhyrWP MnT2NkBp MXzEUXNQ MorWcIVi\HNidH:gVHAzSSCjY4TpeoF1cW:w NXHmS5ZqOjZyMkO4N|Y>
PC-3 MWPD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MVq0NEDDvU1? MkSyNlQwPDhxN{KgbC=> NUDrfJpjTE2VTx?= MknG[IVkemWjc3XzJINmdGxidnnhZoltcXS7IITpcYUh\GWyZX7k[Y51dHl? MoLFNlYxOjN6M{[=
SCG NFfpXlhHfW6ldHnvckBCe3OjeR?= MUiyNEDPxE4EoB?= M2\aU2ROW09? NXjpbW9PemW4ZYLzbYJtgSC|dYDwdoV{e2W|IFnLWkB4cXSqIHGgTWM2OCCxZjCyOE41KM7:TR?= NXLkTFV3OjV7NkKxN|I>
HEK-293 MY\GeY5kfGmxbjDBd5NigQ>? M3y5O|M2KM7:TdMg NV:z[49OTE2VTx?= M4fiPYlv\HWlZYOgZUBkd26|cHnjeY92eyEkgKzpcoFkfGm4YYTpc47jiJ1ib3[geIhmKEu4Mj6xJIN2enKnboS= NWLQNFNLOjV7NkKxN|I>
SCG M3e1OmZ2dmO2aX;uJGF{e2G7 Ml;kNVAxKM7:TdMg MXnEUXNQ M4LxZZJm\HWlZYOgeIhmKGW6Y3n0ZYJqdGm2eTDv[kBUS0dibnX1do9vew>? MYSyOVk3OjF|Mh?=
PCCL3 M3vVPGZ2dmO2aX;uJGF{e2G7 NIToUGoyOCEEtV2= NGfQb|EzPCCq NWLTSldx\W6qYX7j[ZMhTHWReEKgdJJwdW:2ZYKgeJJidnOlcnnweIlwdiCjY4Tpeol1gcLi4pEL MVSyOVk3ODl3Nh?=
3T3-L1 preadipocytes NYrqZlBvTnWwY4Tpc44hSXO|YYm= MmfhNVAh|ryPwrC= MmfZNVIhcA>? NEDJbFRqdmS3Y3XzJGNTTUJicHjvd5Bpd3K7bHH0bY9vKGGwZDDDM2VDWM7{IHX4dJJme3Orb36= MnW4NlU6OjhyNUi=
H295R  NWjvWoE{TnWwY4Tpc44hSXO|YYm= M3jJVVExyqEQvF2= MUS0POKhcA>? MXnpcoNz\WG|ZYOgd5Rmem:rZDDt[ZRi[m:uaYTld{BqdiC2aHWgZY5lem:pZX6sJI1qdmW{YXzvMUBidmRiZ3z1Z49kd3K2aXPvbYQheGG2aIfhfZM> M4XNfVI2QDZ7NUW2
PBMC MmrhSpVv[3Srb36gRZN{[Xl? M1m4fVUxyqEQvF2= NF24cHgzPMLiaNMg NXfq[ox{cW6qaXLpeJMhfGinIHnuZ5Jm[XOnZDDz[YNz\XSrb36gc4YhXE6IIHnu[JVk\WRiYomgeIhmKESSRR?= NUnjeIFEOjV6Nk[wO|k>
GLUTag  NXvROmJqTnWwY4Tpc44hSXO|YYm= NXLk[5FQOTEkgJpCuW0> MlfkNE8zNzRiaB?= NXW0Z3Vye3SrbYXsZZRmeyCJTGCtNUB{\WO{ZYTpc44h[2:2cnXheIVlKHerdHigTWJOYA>? NFn4eW8zPTh|Mk[zNS=>
GLUTag  NUW0dFJZTnWwY4Tpc44hSXO|YYm= NWnGNVlXOTEkgJpCuW0> Mnv3OEBp Mk\mbY5kemWjc3XzJJRp\SCyQ2LFRkBt\X[nbIOge4l1cCC2aHWgTWJOYA>? MVqyOVg{OjZ|MR?=
BAECs NVyxOmF3TnWwY4Tpc44hSXO|YYm= Ml3ONlUh|ryP MnLkNlQhcA>? MXjlcohidmOnczD0bIUh[WO2aY\heIlwdiCxZjDQVGFT|rFiYomgOUDPxE1icnXzeoVz[XS{b3ysJHQ1UFNuIH;yJFQuWEGS NXnOe3E5OjV5OUi4NlY>
PC12 MmTqSpVv[3Srb36gRZN{[Xl? Mn3DNlXDqM7:TR?= M1fpTFQ5KGh? NFq1N2Fi[3SrdnH0[ZMh[0GPUB?= NXnLdVAyOjV5NkmzNFU>
GH3 M4TmbWZ2dmO2aX;uJGF{e2G7 M3rGdFHDqM7:TR?= NHn6XFY3NWh? MlXZZZR1\W63YYTld{B1cGViY3;ydoVt[XSrb36gZoV1f2WnbjDQVmwh[W6mIFLtZYwyKGW6cILld5Nqd25? NVGy[5NvOjV5MkewNVg>
GH3 NHO1e5ZHfW6ldHnvckBCe3OjeR?= MnzsNeKh|ryP NUnSeWF2Pi2q MXnpcoR2[2W|IGDSUEBidmRiQn3hcFEtKGK3dDDuc5QhS2yxY3usJI1TVkFiZYjwdoV{e2mxbh?= M4XMcFI2PzJ5MEG4
BeWo Ml;2SpVv[3Srb36gRZN{[Xl? M{DLN|Ex6oDMzszNxsA> M4WyNVczKGh? M4\idmROW09? MV7t[YRq[XSnczDC[XdwKGOnbHyg[Iln\mW{ZX70bYF1cW:w MUSyOVcyOzR{NR?=
oocytes M13WTGZ2dmO2aX;uJGF{e2G7 MkDFOUDPxE1? MYGyOEBp NXP0fXVy[XS2ZX71ZZRmeyC{aD3pcpN2dGmwIHHjeIlwdiCxbjDvc4N6fGViR2\CSEB{cWewaX\pZ4FvfGy7wrC= NI\pN2wzPTdyN{i1OC=>
SC MVrGeY5kfGmxbjDBd5NigQ>? M{LoW|AvPSEQvF2= NYWxbHE6OjRiaB?= MXftbY1q[2u|IITo[UBm\m[nY4Sgc4Yh[0GPUDDhcoFtd2e|IH;uJG8yKGGwZDDNRnAh\XiycnXzd4lwdg>? NXvmVm1OOjV5MEW4O|Q>
SC MX;GeY5kfGmxbjDBd5NigQ>? NHqydlYxNjVizszN M4XnOVczKGh? M{TRcolv[3KnYYPld{Bjd3SqIFvyc5guOjBiYX7kJG8yKGW6cILld5Nqd25iaX6gZZhwdi2{ZXzheIVlKFOFczDieZQhd26ueTDLdo95NTJywrC= Ml75NlU4ODV6N{S=
UACC-647  MU\GeY5kfGmxbjDBd5NigQ>? NEnRXWlFVVOR MXns[YFleyC2bzDhJJJqe2ViaX6gZ2FOWCCuZY\lcJMhMEWFNUFCpF3DqDJyLkO5xsDPxE1r MljyNlU4ODNyMkW=
UACC-647  Mk\1SpVv[3Srb36gRZN{[Xl? MkPyNVDDqM7:TR?= NWLLW4NIOTVibXnu MWjEUXNQ NW\rVVJ4cW6qaXLpeJMhTVKNIIDoc5NxcG:{eXzheIlwdg>? M2PuNVI2PzB|MEK1
UACC-647  M3qzdGZ2dmO2aX;uJGF{e2G7 MWqxNOKh|ryP NYDRdFdrOTVibXnu MkSwSG1UVw>? NEDEW|BqdmO{ZXHz[ZMh\UWIMjDwbI9{eGixconsZZRqd25ibHX2[Yx{yqB? NHPVV2EzPTdyM{CyOS=>
SH-SY5Y  M4K1dGZ2dmO2aX;uJGF{e2G7 NYHCU2hnOTEEoN88US=> M{nIclHDqGkEoB?= MWXpcoNz\WG|ZYOgUHVEKGGldHn2bZR6 Mlz2NlU2QTd2M{O=
SH-SY5Y  NXrrVYdQTnWwY4Tpc44hSXO|YYm= MmTXNVDDqM7:TR?= NWG3SnN4OcLiaNMg MnzhbY5kemWjc3XzJGFISzFibWLORUBt\X[nbB?= M4LzfVI2PTl5NEOz
hADSCs NU\5[IVxTnWwY4Tpc44hSXO|YYm= MWe15qCKyrWP M2\uc|MxKG2rbh?= M2e0Volv[3KnYYPld{BkSU2SIHzleoVtew>? NFrIWJEzPTV7MUmwPC=>
HEK293  M4Hv[2Z2dmO2aX;uJGF{e2G7 MY[15qCKyrWP NYLxbnZqOzBibXnu NWD5TYZmcW6lcnXhd4V{KGODTWCgcIV3\Wy| NWD4OoNTOjV3OUG5NFg>
3T3-L1 NVLWXHhTTnWwY4Tpc44hSXO|YYm= M4Dn[|IvPS93IN88US=> Mn7INlQhcMLi NGTMSI5{cWewaX\pZ4FvfGy7IHTlZ5Jm[XOnczDBWGdNKHC{b4TlbY4h\XiycnXzd4lwdiCjdDDhcIwh\G:|ZYOgeIV{fGWm NUXxXGN6OjV3OUC1PVc>
OCI-Ly1  MYPGeY5kfGmxbjDBd5NigQ>? MWe0NOKh|ryP MUGxxsBpyqB? Ml6zSG1UVw>? NWTOeXlycW6mdXPld{B1cGViaX7jdoVu\W62IH;mJINCVVBiY3;uZ4VvfHKjdHnvcpM> NVLRWoJyOjV3N{[yNlA>
OCI-Ly18  MoTISpVv[3Srb36gRZN{[Xl? NHr4UVQ1OMLizszN MUixxsBpyqB? M4rj[GROW09? MUjpcoR2[2W|IITo[UBqdmO{ZX3lcpQhd2ZiY1HNVEBkd26lZX70doF1cW:wcx?= MoHPNlU2PzZ{MkC=
BeWo M2XtVGZ2dmO2aX;uJGF{e2G7 MUSyNOKhyrWP M1vo[VQ5yqCq MnfRSG1UVw>? NHjHSWpqdmO{ZXHz[ZMhfGinIHTp[oZmemWwdHnheIlwdiCxZjDC[XdwKGOnbHzz Mk\KNlU2PjZ5NEC=
BeWo Ml\wSpVv[3Srb36gRZN{[Xl? M3XOT|IxyqEEtV2= M{PPUlQ5yqCq M{fhTWROW09? NGXQbmJqdmO{ZXHz[ZMhfGinIHHkbIV{cW:wIH;mJHRJWC1zIH3vco9kgXSncx?= NHzWT|MzPTV4Nke0NC=>
LNCaP  MU\GeY5kfGmxbjDBd5NigQ>? NHzP[HMyOMLizszN M1T4RVEzKGkEoB?= MmG2SG1UVw>? M{DiZYlv\HWlZYOgZUBlemGvYYTpZ{BqdmO{ZXHz[UBw\iCFUlXCNUBi[3Srdnn0fS=> M1HMUlI2PTR6MEm5
ThGCs  NXfvT5hGTnWwY4Tpc44hSXO|YYm= M13rTlEx6oDMzszN MUC05qCLcA>? NUnPZoZ5[XWpbXXueJMhUEmIMVGgcIV3\Wy|IIToZZQhf2W{ZTDzeIlufWyjdHXkJIJ6KEOxQ3yy MXiyOVQ{OzB{Nx?=
ThGCs  NX;oUo84TnWwY4Tpc44hSXO|YYm= M{nqT|Ex6oDMzszN NIDFZ2c16oDMaB?= NXv6V2o4cW6lcnXhd4V{KEOxQ3yyMYlv\HWlZXSgSWRPOsLiZ3Xu[UBmgHC{ZYPzbY9v MWSyOVQ{OzB{Nx?=
ThGCs  M{foeGZ2dmO2aX;uJGF{e2G7 NXz2dpFCOTEkgJtOwG0> MkXzN{Bp Mn:ybY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCKMl:yJI9vKEWGTkKgcXJPSQ>? MmnmNlU1OzNyMke=
RBMECs Ml70SpVv[3Srb36gRZN{[Xl? NV24OoxROC5yNT:wMlUwPSEQvF2= MlHXNE4zPSCq M{LObolv[3KnYYPld{BkSU2SIHPvcoNmdnS{YYTpc44> NETiUGkzPTRzNk[1NS=>
RBMECs NVnvVpZKTnWwY4Tpc44hSXO|YYm= NECy[FY2yqEQvF2= M4O0eFEhcA>? NFS0bJRjdG:la4OgeIhmKGGldHn2ZZRqd25ib3[gVohwSS:UT1PLJIlv\HWlZXSgZpkhTU2DUD3JTS=> NVjxZXhUOjV2MU[2OVE>
RBMECs MWnGeY5kfGmxbjDBd5NigQ>? NH\UXIY2yqEQvF2= MWexJIg> NIL5fVRxemW4ZX70d{B1cGViRV3BVE1KUS2rbnT1Z4VlKFSHRWKgeoFtfWViZHXjdoVie2V? M1XXVlI2PDF4NkWx
RBMECs MnWwSpVv[3Srb36gRZN{[Xl? NVjl[IJqPcLizszN NXrlRXl{OSCq NIPGNppxemW4ZX70d{B1cGViaX7jdoVie2ViaX6gTHJRKG[udYigZYNzd3O|IITo[UBDXEJiaX7keYNm\CCkeTCgSW1CWC2LSR?= MlexNlU1OTZ4NUG=
RBMECs M2TUW2Z2dmO2aX;uJGF{e2G7 NWXFN|hPPcLizszN MmTYNUBp NUDnWJZlcW6qaXLpeJMhfGinIHTlZ5Jm[XOnZDDv[kBidW:3boSgc4YhYk9vMTDpckBOTnNiaX7keYNm\CCkeTDFUWFRNUmL NGC3SIYzPTRzNk[1NS=>
RBMECs NXXmXlZKTnWwY4Tpc44hSXO|YYm= MWi1xsDPxE1? MmHVNUBp NYDq[mlxemW4ZYLz[ZMhfGinIHPoZY5o\XNiaX6gXm8uOSCmaYP0doljfXSrb36gd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70 MkmwNlU1OTZ4NUG=
RBMECs M2W4OGZ2dmO2aX;uJGF{e2G7 M4[3TFXDqM7:TR?= M4\CfVEhcA>? M4jQSIJtd2OtczD0bIUhTU2DUD3JTU1qdmS3Y3XkJINp[W6pZTDpckBOVENicHjvd5Bpd3K7bHH0bY9v NYiwUFdTOjV2MU[2OVE>
RBMECs MkHzSpVv[3Srb36gRZN{[Xl? NXj3XohDPcLizszN NIjtT|AyKGh? M3X2ToJtd2OtczD0bIUh[WO2aX6gZ5l1d3OtZXzleI9vKHKnYYLyZY5o\W2nboSgd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70xsA> NFnpSlUzPTRzNk[1NS=>
Primary bovine chondrocytes M3rqRWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 Ml72Oe69VQ>? MVG0PEBp NWrqUmFkemW4ZYLz[ZMhfGinIHnubIljcXSxcomg[YZn\WO2IH;mJINmdGWlb4jpZkBwdiCycn;sbYZmemG2aX;uJIlvKGe{b4f0bEBxdGG2ZTDjbI9v\HKxY4n0[ZM> MoHxNlU1ODZyMU[=
EM1  MVjGeY5kfGmxbjDBd5NigQ>? MmLONVXjiIsQvF2= NWrPfJE6PDhiaB?= MVjy[YR2[2W|IITo[UBmgHC{ZYPzbY9vKG:owrDMTWbDqG:{wrDQWGdUOsLiaX9CpGNCVFJvIH;yxsBGWEGFMj3zbYxmdmOnZDDFUVEh[2WubIRCpC=> MofUNlU{Pzh4NkG=
BeWo  M1;sXGZ2dmO2aX;uJGF{e2G7 MkXINlDDqML3TR?= NF[1T401QMLiaNMg NHrpSJRFVVORwrC= NH:4Oo1qdmO{ZXHz[ZMhfGinIHLleIEucEOJIILlcIVie2V? NHr2fGczPTN4MkK2NC=>
BeWo  M3j3dGZ2dmO2aX;uJGF{e2G7 NIjKcIIzOMLiwsXN MmLQOFjDqGkEoB?= NWXRe2RGTE2VT9Mg NGjWc4hld3ewcnXneYxifGW|IITo[UBt\X[nbDDv[kBVVUWPRkG2 MnXBNlU{PjJ{NkC=
BeWo  Mke5SpVv[3Srb36gRZN{[Xl? M{fZT|IxyqEEtV2= NV7OSnRuPDkEoHlCpC=> M2PxfmROW00EoB?= M3LLO4Rwf26{ZXf1cIF1\XNidHjlJIxmfmWuIH;mJGdEVS1z MUOyOVM3OjJ4MB?=
granulosa cells MkS1SpVv[3Srb36gRZN{[Xl? MWmxNEDPxE1? NGSz[WYyOi9{NDDo NW\xfmt1cW6lcnXhd4V{KHSqZTDs[ZZmdHNib3dCpHJIWzMEoH3SUmE> NF3zeWUzPTN|OUGwOS=>
granulosa cells NXPwPWpoTnWwY4Tpc44hSXO|YYm= MmPwNVAh|ryP NHPWV5oyOi9{NDDo M3P4WYlv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= MUGyOVM{QTFyNR?=
granulosa cells NYnBV5pZTnWwY4Tpc44hSXO|YYm= M3LnTVExKM7:TR?= M{\LfFI1KGh? M13rZolv[3KnYYPld{B1cGViaX70[Y5{cXS7IH;mJGRPSS:ycn;0[YlvKGOxbYDs[Zg> NF\tOokzPTN|OUGwOS=>
granulosa cells MmTHSpVv[3Srb36gRZN{[Xl? Ml;RNVAh|ryP NXHqbYtQOjRiaB?= NEfWXnpqdmO{ZXHz[ZMhfGinIHzleoVteyCxZjDSS3MzKHC{b33veIVzKGGldHn2bZR6 NFi2SXczPTN|OUGwOS=>
SK-N-AS  NHK1T2ZE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NEDOTowyOCEQvF5CpC=> NVPDZVZYOjRxNEigbC=> NUjHXlA4\W6qYX7j[ZMhfGmvZT3k[ZBmdmSnboTsfUBk\WyudXzhdkB3cWGkaXzpeJnDqA>? M{XtRlI2OjZ4ME[z
SK-N-AS  MnrxSpVv[3Srb36gRZN{[Xl? Mmq1NVAh|ryPwrC= NHi4NmwzPCCq NIn5NZVqdmO{ZXHz[ZMhfGinIHPBUXAhdGW4ZXzzxsA> MXuyOVI3PjB4Mx?=
SK-N-AS  MkHwSpVv[3Srb36gRZN{[Xl? MljmNVAh|ryPwrC= MVSyOEBp M2DlU4lv[3KnYYPld{B1cGViZYjwdoV{e2mxbjDv[kBkgWOuaX6gSFE> MV6yOVI3PjB4Mx?=
SK-N-AS  MkW0SpVv[3Srb36gRZN{[Xl? MlPLNVAh|ryPwrC= NIfiblU{OCCvaX6= NVjXT2VJcW6mdXPld{BxcG:|cHjvdplt[XSrb36gc4Yh|rJvY3H0[Y5qdiBqc3XyOlc2MSxicD3HV2s{|rJiKIPldlkqKGGwZDDjc45kd22rdHHueEBpcWeqZYKgcIV3\Wy|IH;mJIFkfGm4ZTygeY5xcG:|cHjvdplt[XSnZDyg{tIu[2G2ZX7pci=> M4rzSlI2OjZ4ME[z
SK-N-AS  MU\GeY5kfGmxbjDBd5NigQ>? NHvlOWwyOCEQvF5CpC=> MkH3NVAwOzBxNkCgcYlv NVT4R|JbcW6lcnXhd4V{KGyndnXsd{Bw\iCyLd8yMYNifGWwaX6gLJNmejZ5NTmgZY5lKGmwZIXj[ZMh[WOldX31cIF1cW:wIH;mJJAu|rJvY3H0[Y5qdiBqc3XyOlc2MSCrbjCodIVzcSmwdXPs[YFzKHKnZ3nvcpM> MVmyOVI3PjB4Mx?=
SK-N-SH MoPRR4VtdCCYaXHibYxqfHliQYPzZZk> M2ruOFExKM7:TdMg NHuyWJI1QCCq MXflcohidmOnczDTT{1PNVOKIH7leZJw[myjc4TvcYEh[2WubDD2bYFjcWyrdIm= NFzC[YwzPTJ4NkC2Ny=>
HEK‐CFTR Ml3hSpVv[3Srb36gRZN{[Xl? Ml73NwKBmzVywrFOwG0> NIDQbJUxNTF{IH3pci=> NIi4TmtFVVORwrC= NInVPFlqdmS3Y3XzJIEh\G:|ZfMAlIRmeGWwZHXueEBqd2SrZHWg[YZndHW6wrC= MoHONlUzPjN{MEe=
L6 MUnGeY5kfGmxbjDBd5NigQ>? MX[0NEDDvU1? NGLiPJgzPCCq NWrEc2xrcW6qaXLpeJMhTE2KMT3pcoR2[2WmIFHreEBi[3SrdnH0bY9v NH3aOZkzPTJ2N{W1NC=>
MIN6  M4P2Z2Z2dmO2aX;uJGF{e2G7 MX[xNEDPxE4EoB?= MlXlN{Bp NXvOWVB1cW6lcnXhd4V{KER|IH3SUmEh\XiycnXzd4lwdg>? MV2yOVI1OTF{NB?=
ventricular cardiomyocytes  NYj1SFBsTnWwY4Tpc44hSXO|YYm= NX7Fd2ZmOC5yMT2xNEDPxE1? NWWy[IRycW6lcnXhd4V{KCClQV3QJIFk[3WvdXzheIlwdg>? NUDnVZBjOjV{MEOxNVM>
ventricular cardiomyocytes  MVjGeY5kfGmxbjDBd5NigQ>? MVmwMlAyNTFyIN88US=> NYjE[XVw\X[xa3XzJIFvKGmwb4Tyc5Bq[yC{ZYPwc45{\SBzMkFCtVE2LSCjYn;2[UBj[XOjbDD3bZRpKGGwIFXDOVDDqG:oIEKuNkDDvU1? MnLLNlUzODNzMUO=
BeWo  MofRSpVv[3Srb36gRZN{[Xl? NUP0TXlPOjBiwsXN MonSOFghcA>? NHvGO3lFVVORwrC= NIHvWGxqdmS3Y3XzJINmdGxiZoXzbY9v MUKyOVE5PDR5Nx?=
THP-1  NXPXfZF5TnWwY4Tpc44hSXO|YYm= NXTpSW1QOS9zMDFOwG0> NFiwVHQzyqCq Ml\iSG1UV8Li MmLCd5VxeHKnc4Pld{BOS1BvMTDwdo9lfWO2aX;uxsA> Ml\DNlUyPTR6OEK=
Huh-7 NVzMfG1jTnWwY4Tpc44hSXO|YYm= MorFNE0zOCEQvF2= Mn7KNkBpyqB? Mn3ZdoV{fWy2czDpckBiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGNvTYnjJIV5eHKnc4Ppc44h[XRidHjlJJBzd3SnaX6gZY5lKG2UTlGgcIV3\Wy| MlLnNlUyODl6M{S=
C6 M1yycGZ2dmO2aX;uJGF{e2G7 NXjrPVdKOTBizszNxsA> MljqNlAhdWmw NWHNcW1FcW6lcnXhd4V{KGODTWCgZYNkfW23bHH0bY9v NUXN[|BTOjVyNkm0NVc>
SW480 M3rNb2Z2dmO2aX;uJGF{e2G7 M2SzcVQxyqEQvF2= NF7rXZU1QMLiaB?= MWrEUXNQ NXu3[nZ7[WO2aY\heIV{KFCSMlG= NWTTZXVnOjR7OUe0OVE>
HT-29  MkHySpVv[3Srb36gRZN{[Xl? NIPO[og1OMLizszN NH;QTpY1QMLiaB?= NEjiSJVFVVOR MWPhZ5RqfmG2ZYOgVHAzSQ>? NWjxclhLOjR7OUe0OVE>
SW480 NYnwWXptT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MnPiOFDDqM7:TR?= NEftTI8xNTd{IHi= MmX2SG1UVw>? MlXxbY5pcWKrdIOgZ4VtdCCpcn;3eIghfGmvZTDk[ZBmdmSnboTsfS=> MUWyOFk6PzR3MR?=
HT-29  NIn1RZJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NFzhSHA1OMLizszN NWrOd49DOC15MjDo MmHPSG1UVw>? NXTGPJk4cW6qaXLpeJMh[2WubDDndo94fGhidHnt[UBl\XCnbnTlcpRtgQ>? NI\VdnMzPDl7N{S1NS=>
SW480 Ml7hSpVv[3Srb36gRZN{[Xl? MlvSOFDDqM7:TR?= NYnUO2FEPyCm NFvXcI1FVVOR NEXhbmRz\WS3Y3XzJINwdG:wb4PwbIVz\SCob4LtZZRqd25iY3HwZYJqdGm2edMg NFn1dJozPDl7N{S1NS=>
HT-29  NI\XSmZHfW6ldHnvckBCe3OjeR?= NHn1coM1OMLizszN MXW3JIQ> MomwSG1UVw>? M1fI[5Jm\HWlZYOgZ49td26xc4Do[ZJmKG[xcn3heIlwdiClYYDhZoltcXS7wrC= NGL4RYMzPDl7N{S1NS=>
SW480 NXftcFd6SXCxcITvd4l{KEG|c3H5 Mkf4OFDDqM7:TR?= NVeyeXdJPDkEoHi= NFnKWFNFVVOR MoDYbY5lfWOnczDhckBi[3SrdnH0bY9vKG:oIHPhd5Bie2ViMz:3 MWCyOFk6PzR3MR?=
HT-29  MVTBdI9xfG:|aYOgRZN{[Xl? NV;aT5pUPDEEoN88US=> NWTxUXVTPDkEoHi= MmLkSG1UVw>? MlizbY5lfWOnczDhckBi[3SrdnH0bY9vKG:oIHPhd5Bie2ViMz:3 NW\WdGd[OjR7OUe0OVE>
SW480 M4HBeWFxd3C2b4Ppd{BCe3OjeR?= NV3UbYhUPDEEoN88US=> M1vITFQ5yqCq MYXEUXNQ M{PFeYlv\HWlZYOgZ4hidmenczDpckB1cGVicHjvd5Bpd3K7bHH0bY9vKHO2YYT1d{Bw\iCSUELBJJRiemendIO= M4HveFI1QTl5NEWx
HT-29  Mo\lRZBweHSxc3nzJGF{e2G7 NX;BUmVqPDEEoN88US=> Mn;vOFjDqGh? MoHUSG1UVw>? NHvvTpZqdmS3Y3XzJINp[W6pZYOgbY4hfGinIIDoc5NxcG:{eXzheIlwdiC|dHH0eZMhd2ZiUGCyRUB1[XKpZYTz NIPTOGUzPDl7N{S1NS=>

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null --

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID