Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 Mn\NSpVv[3Srb36gRZN{[Xl? MUWxNEDPxE1? NEDPUZc3KGh? MX\pcoNz\WG|ZYOgdIhwe3Cqb4L5cIF1cW:wIH;mJI93\XKneIDy[ZN{\WRiS1zIUFMh[XRiU{SzNy=> MoPCNlY1OzV2OUi=
Mo-DCs M1XpNGZ2dmO2aX;uJGF{e2G7 MUm1NEDPxE1? NVL5NFE6OjUkgJno MlnFdJJwdW:2ZYOgTWwuOjNicILv[JVkfGmxbjDpckB1cGVic4Xw[ZJv[XSjboSgc4Yhgnmvb4PhckB{fGmvdXzheIVlKE2xLVTDd:Kh NGX5PXUzPjRzMkm0PC=>
RBMECs  NYrENmF{TnWwY4Tpc44hSXO|YYm= NX;LUGZZPcLizszN MVSxxsBp MYLicI9kc3NidHjlJHJi[zFiaX7hZ5RqfmG2aX;uJIlv\HWlZXSgZpkhTU2DUD3JTS=> MojQNlY{PThyM{m=
INA-6 MYnD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M1HLTVAuOTByIN88US=> M17EN|cz6oDLaB?= MXfpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= NHzNc4EzPjNyNk[yOC=>
OPM-2 MWXD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MnXONE0yODBizszN MUG3NwKBkWh? Mn7pbY5lfWOnczDj[YxtKGSnYYToJIRwe2ViZHXw[Y5l\W62bIm= MUOyOlMxPjZ{NB?=
U266 NF\Rc3BE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NG\ISIIxNTFyMDFOwG0> MlH5O|LjiImq NHjwXZFqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> NGL2d4YzPjNyNk[yOC=>
H929 MUPD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M1XOSFAuOTByIN88US=> MoHlO|LjiImq NEfMfolqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> NEfpeVQzPjNyNk[yOC=>
RPMI 8226 MWLD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M{T6PVAuOTByIN88US=> MlzDO|LjiImq NHPpd2pqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> MXKyOlMxPjZ{NB?=
MDCK  MmP5SpVv[3Srb36gRZN{[Xl? MlHDNVAhyrWP MVSyOEBp M2\tdGROW09? NYLuR3hTfXC{ZXf1cIF1\XNidHjlJIV5eHKnc4Ppc44hd2ZiVFfGMe6zOSCjbnSgR3RITsLi NVr1bXpQOjZ{MEKzOVI>
MDCK  NIrMfJlHfW6ldHnvckBCe3OjeR?= MnzkNVAhyrWP MkWyNlQhcA>? MVLEUXNQ NH3l[41qdmirYnn0d{B1cGViaX7jdoVie2WmIHX4dJJme3Orb36gc4YhTk5iY3H1d4VlKGK7IGTHSk3PujF? NIrLTIczPjJyMkO1Ni=>
Spinal cords  NGDhSWNHfW6ldHnvckBCe3OjeR?= M2XNe|HDqM7:TR?= NGTj[WE{OCCvaX6= MXLzeIlufWyjdHXzJINCVVBibHX2[Yx{ NXzUVlFyOjZzMk[5NlY>
BeWo  NUGyb4FvTnWwY4Tpc44hSXO|YYm= M4LZeFI26oDLzszN M4TTNlI1NzR6L{eyJIg> NGe1b4dt\WGmczD0c{BidiCrbnPy[YF{\SCrbjD0bIUh\XiycnXzd4lwdiCxZjDveIhmeiCodYPpc44hdWG{a3Xydy=> MoPFNlYxPTN3NEm=
bovine oocytes M2DZSWZ2dmO2aX;uJGF{e2G7 NWD2[WM4OTBywrFOwG0> MkTlNVLDqGh? MnfjbY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCQUGDBJIFv\C:xcjDOVHBEKHSxIIP0bY12dGG2ZTDy[ZN2dXC2aX;uJI9nKG2naX;zbZM> NV7a[2FbOjZyNUG2NVE>
Caco-2  NH\mW2lHfW6ldHnvckBCe3OjeR?= MknFNE4yNzFxMUCg{txO MY[yNOKhdWmw NUnmeFBlcW6mdXPld{BiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGmwdILhZ4VtdHWuYYKgZ2FOWCCuZY\lcJM> NVrvUHJROjZyNEmxNFI>
Caco-2  MWnGeY5kfGmxbjDBd5NigQ>? NGXsOpAxNjFxMT:xNEDPxE1? M4f2OlI1KGh? M1\2Rolv[3KnYYPld{BOWlB{IIDyc5RmcW5ibHX2[Yw> MWSyOlA1QTFyMh?=
AML-12  MWXGeY5kfGmxbjDBd5NigQ>? MnOwNlAh|ryP M1\zWlMhcA>? NUD4RYUzfXC{ZXf1cIF1\XNidHjlJJBpd3OyaH;yfYxifGmxbjDs[ZZmdHNiYYSgWIhzNTRzMTDhcoQhW2W{LUS5Ny=> NFLPZoEzPjB2OEm4OS=>
AML-12  MXXGeY5kfGmxbjDBd5NigQ>? MnrKNlAh|ryP M1;1O|EuQCCq NFjJb3VqdmO{ZXHz[ZMh\2y3Y3;z[UBxem:mdXP0bY9v MUeyOlA1QDl6NR?=
AML-12  M3TIT2Z2dmO2aX;uJGF{e2G7 NXLhRldXOjBizszN NInMTok{KGh? NV6wdoZofXBvcnXneYxifGW|wrDQ[4My[S{EoGDldINsNCCjbnVCpGc3eGQEoH3SUmEhdGW4ZXzz NWSySotPOjZyNEi5PFU>
AML-12  NVHQNY51TnWwY4Tpc44hSXO|YYm= M4m0U|IxKM7:TR?= M4PKVFMhcA>? MW\pcoR2[2W|IITo[UBl\XCqb4PwbI9zgWyjdHnvckBw\iCFUmTDNuKh NWXF[GtDOjZyNEi5PFU>
RBMECs MnzFSpVv[3Srb36gRZN{[Xl? M{XDW|XDqM7:TR?= M{HnOlEhcA>? NIezdmdqdmirYnn0d{BGVUGSLVnJMYlv\HWlZXSgbY5i[3SrdnH0bY9vKG:oIGLhdFHDqA>? M{juRlI3ODR2Nk[z
EndoC-βH1 MYDGeY5kfGmxbjDBd5NigQ>? MlzNOeKh|ryP MYOxJIg> NFv2eldxd3SnboTpZZRmeyCpbIXjc5NmNWmwZIXj[YQhcW6|dXzpckB{\WO{ZYTpc44hcW5idHjlJJBz\XOnbnPlJI9nKGeudXPvd4U> M4nCPFI3ODJ6NU[y
EndoC-βH1 NGO1U5NHfW6ldHnvckBCe3OjeR?= NV:5cJhOPcLizszN MlLHNUBp M2HJOoxm[WS|IITvJIEhe3S{b37nJINCVVBiaX7jdoVie2V? MV6yOlAzQDV4Mh?=
SH-SY5Y MYXGeY5kfGmxbjDBd5NigQ>? MmfnN|Ah|ryP NGHUfXk{OCCvaX6= M2fFcWROW09? Ml3Td4lodmmoaXPhcpRtgSCrbnPy[YF{\XNidHjlJIFkfGm4YYTpc44hd2ZiUFvB M3;kZVI3ODJ3MUO3
PC-3 MYnGeY5kfGmxbjDBd5NigQ>? NULPbY5JPDBiwsXN MlHRNkBp NYq2U5FoTE2VTx?= NGj0Z|Ft\WGmczD0c{BRWDKDIHHjeIl3[XSrb36= MX:yOlAzOzh|Nh?=
PC-3 Ml\QR4VtdCCYaXHibYxqfHliQYPzZZk> MmjtOFAhyrWP MVSyOE81QC95MjDo MoLRSG1UVw>? MYHk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHlidHnt[UBl\XCnbnTlcpRtgQ>? M4\OVFI3ODJ|OEO2
SCG NIC1[FBHfW6ldHnvckBCe3OjeR?= NG[5XIwzOCEQvF5CpC=> M2fkeGROW09? NUHZT412emW4ZYLzbYJtgSC|dYDwdoV{e2W|IFnLWkB4cXSqIHGgTWM2OCCxZjCyOE41KM7:TR?= NWrKSYxyOjV7NkKxN|I>
HEK-293 M3TjVGZ2dmO2aX;uJGF{e2G7 NF:xZVA{PSEQvF5CpC=> MV3EUXNQ Mn;vbY5lfWOnczDhJINwdnOyaXP1c5V{KOLCnHnuZYN1cX[jdHnvcwKBpSCxZjD0bIUhU3Z{LkGgZ5VzemWwdB?= MW[yOVk3OjF|Mh?=
SCG MX\GeY5kfGmxbjDBd5NigQ>? MUKxNFAh|ryPwrC= NWjLWGlRTE2VTx?= M4nYTpJm\HWlZYOgeIhmKGW6Y3n0ZYJqdGm2eTDv[kBUS0dibnX1do9vew>? MWGyOVk3OjF|Mh?=
PCCL3 M1S2XWZ2dmO2aX;uJGF{e2G7 M{n0Z|ExKML3TR?= M2PEblI1KGh? NUK2TGZF\W6qYX7j[ZMhTHWReEKgdJJwdW:2ZYKgeJJidnOlcnnweIlwdiCjY4Tpeol1gcLi4pEL MnixNlU6PjB7NU[=
3T3-L1 preadipocytes M2LTb2Z2dmO2aX;uJGF{e2G7 NFG2dIoyOCEQvF5CpC=> NEf1R|IyOiCq NVLVb2pZcW6mdXPld{BEWkWEIIDoc5NxcG:{eXzheIlwdiCjbnSgR{9GSlEQsjDlfJBz\XO|aX;u M2XuPVI2QTJ6MEW4
H295R  M2rFdmZ2dmO2aX;uJGF{e2G7 NF\Sc|kyOMLizszN Mk\HOFjDqGh? M3;JUYlv[3KnYYPld{B{fGW{b3nkJI1mfGGkb3zpeIV{KGmwIITo[UBidmS{b3flckwhdWmwZYLhcI8uKGGwZDDncJVkd2OxcoTpZ49q\CCyYYToe4F6ew>? NVfuZYJSOjV6Nkm1OVY>
PBMC M3HONGZ2dmO2aX;uJGF{e2G7 Mn\YOVDDqM7:TR?= NI\icGwzPMLiaNMg Mn7TbY5pcWKrdIOgeIhmKGmwY4LlZZNm\CC|ZXPy[ZRqd25ib3[gWG5HKGmwZIXj[YQh[nlidHjlJGRRTQ>? NEHn[pMzPTh4NkC3PS=>
GLUTag  MkfESpVv[3Srb36gRZN{[Xl? MkH0NVDjiIoEtV2= M{TPRVAwOi92IHi= M4fRR5N1cW23bHH0[ZMhT0ySLUGgd4VkemW2aX;uJINwfHKnYYTl[EB4cXSqIFnCUXg> MojUNlU5OzJ4M{G=
GLUTag  NFX5dY9HfW6ldHnvckBCe3OjeR?= Mnj5NVDjiIoEtV2= M1LCNFQhcA>? NGjobZVqdmO{ZXHz[ZMhfGinIIDDVmVDKGyndnXsd{B4cXSqIITo[UBKSk2[ M2nnbVI2QDN{NkOx
BAECs NHTxN4tHfW6ldHnvckBCe3OjeR?= NVHBOVByOjVizszN NWfm[2ZLOjRiaB?= NILKTphmdmijbnPld{B1cGViYXP0bZZifGmxbjDv[kBRWEGUzsGgZpkhPSEQvF2gdoV{fmW{YYTyc4wtKFR2SGOsJI9zKDRvUFHQ M4fablI2Pzl6OEK2
PC12 M4i3ZWZ2dmO2aX;uJGF{e2G7 M{jsPFI2yqEQvF2= M33FUlQ5KGh? MVLhZ5RqfmG2ZYOgZ2FOWA>? NWnkW2tmOjV5NkmzNFU>
GH3 MVvGeY5kfGmxbjDBd5NigQ>? M1LjTFHDqM7:TR?= NVf1Z|hlPi2q MmnTZZR1\W63YYTld{B1cGViY3;ydoVt[XSrb36gZoV1f2WnbjDQVmwh[W6mIFLtZYwyKGW6cILld5Nqd25? MnTwNlU4OjdyMUi=
GH3 NHfIT3BHfW6ldHnvckBCe3OjeR?= NEXwXI4yyqEQvF2= MYC2MYg> MXXpcoR2[2W|IGDSUEBidmRiQn3hcFEtKGK3dDDuc5QhS2yxY3usJI1TVkFiZYjwdoV{e2mxbh?= M2XJd|I2PzJ5MEG4
BeWo NEWwdVdHfW6ldHnvckBCe3OjeR?= NG\MVYQyOOLCit88UeKh MkjhO|IhcA>? MoHuSG1UVw>? MVnt[YRq[XSnczDC[XdwKGOnbHyg[Iln\mW{ZX70bYF1cW:w MXSyOVcyOzR{NR?=
oocytes NWXaUpFiTnWwY4Tpc44hSXO|YYm= NXvBVFFlPSEQvF2= Mn7CNlQhcA>? M3fYVoF1fGWwdXH0[ZMhemhvaX7zeYxqdiCjY4Tpc44hd25ib3;jfZRmKEeYQlSgd4lodmmoaXPhcpRtgcLi MWeyOVcxPzh3NB?=
SC MWXGeY5kfGmxbjDBd5NigQ>? MoDTNE42KM7:TR?= MUKyOEBp NELmc2hucW2rY3vzJJRp\SCnZn\lZ5Qhd2ZiY1HNVEBidmGub3fzJI9vKE9zIHHu[EBOSlBiZYjwdoV{e2mxbh?= NXvY[|NSOjV5MEW4O|Q>
SC NEHhOJBHfW6ldHnvckBCe3OjeR?= NECyR4MxNjVizszN MXy3NkBp MoHRbY5kemWjc3XzJIJwfGhiS4LvfE0zOCCjbnSgU|Eh\XiycnXzd4lwdiCrbjDhfI9vNXKnbHH0[YQhW0O|IHL1eEBwdmy7IFvyc5guOjEEoB?= MnTUNlU4ODV6N{S=
UACC-647  MnXhSpVv[3Srb36gRZN{[Xl? M13oTGROW09? MnmzcIVi\HNidH:gZUBzcXOnIHnuJINCVVBibHX2[Yx{KCiHQ{WwxsA:yqB{MD6zPeKh|ryPKR?= NWrzfpRJOjV5MEOwNlU>
UACC-647  NGn4dlBHfW6ldHnvckBCe3OjeR?= MorFNVDDqM7:TR?= M3PubFE2KG2rbh?= NXXzWmk4TE2VTx?= NGrMN3lqdmirYnn0d{BGWkticHjvd5Bpd3K7bHH0bY9v M1rJO|I2PzB|MEK1
UACC-647  MWXGeY5kfGmxbjDBd5NigQ>? M{fp[FExyqEQvF2= M360TVE2KG2rbh?= NUXBO286TE2VTx?= M3TvU4lv[3KnYYPld{BmTUZ{IIDoc5NxcG:{eXzheIlwdiCuZY\lcJPDqA>? NYO3bHVuOjV5MEOwNlU>
SH-SY5Y  Mni4SpVv[3Srb36gRZN{[Xl? NUL6U2xsOTEEoN88US=> MUWxxsBpyqB? Mm\MbY5kemWjc3XzJGxWSyCjY4Tpeol1gQ>? NFH4[YszPTV7N{SzNy=>
SH-SY5Y  MUXGeY5kfGmxbjDBd5NigQ>? MVWxNOKh|ryP NGDaXoMyyqCqwrC= M2mzfIlv[3KnYYPld{BCT0NzIH3SUmEhdGW4ZXy= NV7O[IpZOjV3OUe0N|M>
hADSCs Mm\rSpVv[3Srb36gRZN{[Xl? MWO15qCKyrWP MlTUN|AhdWmw M3\FU4lv[3KnYYPld{BkSU2SIHzleoVtew>? M1W2c|I2PTlzOUC4
HEK293  M{LkOGZ2dmO2aX;uJGF{e2G7 NYrHbplFPeLCidM1US=> NGPMeXQ{OCCvaX6= NFTEUVJqdmO{ZXHz[ZMh[0GPUDDs[ZZmdHN? MYqyOVU6OTlyOB?=
3T3-L1 NWPxS3ZMTnWwY4Tpc44hSXO|YYm= NV;BS2R1Oi53L{Wg{txO NEXDVHczPCCqwrC= Mn\2d4lodmmoaXPhcpRtgSCmZXPy[YF{\XNiQWTHUEBxem:2ZXnuJIV5eHKnc4Ppc44h[XRiYXzsJIRwe2W|IITld5Rm\A>? NWPWc2g1OjV3OUC1PVc>
OCI-Ly1  NWnYOYVHTnWwY4Tpc44hSXO|YYm= MoPHOFDDqM7:TR?= MlXpNeKhcMLi MV\EUXNQ NGTR[IFqdmS3Y3XzJJRp\SCrbnPy[Y1mdnRib3[gZ2FOWCClb37j[Y51emG2aX;udy=> M3y4TFI2PTd4MkKw
OCI-Ly18  NXPoWZZxTnWwY4Tpc44hSXO|YYm= NXnTOHJkPDEEoN88US=> Ml3YNeKhcMLi M3\OfGROW09? MYrpcoR2[2W|IITo[UBqdmO{ZX3lcpQhd2ZiY1HNVEBkd26lZX70doF1cW:wcx?= NV7hTZJCOjV3N{[yNlA>
BeWo NVnlZ|dCTnWwY4Tpc44hSXO|YYm= M3;UcVIxyqEEtV2= M4nSNVQ5yqCq NEnIRXBFVVOR MlLvbY5kemWjc3XzJJRp\SCmaX\m[ZJmdnSrYYTpc44hd2ZiQnXXc{Bk\Wyucx?= MUCyOVU3Pjd2MB?=
BeWo MnzISpVv[3Srb36gRZN{[Xl? MlPDNlDDqML3TR?= NVLSbZJWPDkEoHi= Mor6SG1UVw>? MXTpcoNz\WG|ZYOgeIhmKGGmaHXzbY9vKG:oIGTIVE0yKG2xbn;jfZRmew>? NInocWkzPTV4Nke0NC=>
LNCaP  M2LsdWZ2dmO2aX;uJGF{e2G7 M1fMPVExyqEQvF2= M2rqcFEzKGkEoB?= NETucIpFVVOR NEXWN5RqdmS3Y3XzJIEh\HKjbXH0bYMhcW6lcnXhd4Uhd2ZiQ2LFRlEh[WO2aY\peJk> MWmyOVU1QDB7OR?=
ThGCs  NUnxfGxqTnWwY4Tpc44hSXO|YYm= M3nMdlEx6oDMzszN Ml\xOQKBkmh? MUTheYdu\W62czDITWYySSCuZY\lcJMhfGijdDD3[ZJmKHO2aX31cIF1\WRiYomgR49EdDJ? M3\T[FI2PDN|MEK3
ThGCs  M{nxVGZ2dmO2aX;uJGF{e2G7 MY[xNQKBks7:TR?= MYK05qCLcA>? NX;CW2pFcW6lcnXhd4V{KEOxQ3yyMYlv\HWlZXSgSWRPOsLiZ3Xu[UBmgHC{ZYPzbY9v M2\nWVI2PDN|MEK3
ThGCs  NGDwc3BHfW6ldHnvckBCe3OjeR?= Mn3pNVDjiIsQvF2= NUj4XmtZOyCq NE\zb4FqdmirYnn0d{B1cGViZX\m[YN1KG:oIFiyU|Ihd25iRVTONkBuWk6D NIHGXGwzPTR|M{CyOy=>
RBMECs MVXGeY5kfGmxbjDBd5NigQ>? MnTENE4xPS9yLkWvOUDPxE1? NXHMbZpyOC5{NTDo MXfpcoNz\WG|ZYOgZ2FOWCClb37j[Y51emG2aX;u MWSyOVQyPjZ3MR?=
RBMECs M2S1TGZ2dmO2aX;uJGF{e2G7 NXPnTnpCPcLizszN MljBNUBp M3zHR4Jtd2OtczD0bIUh[WO2aY\heIlwdiCxZjDSbI9CN1KRQ1ugbY5lfWOnZDDifUBGVUGSLVnJ MUOyOVQyPjZ3MR?=
RBMECs MljCSpVv[3Srb36gRZN{[Xl? MX:1xsDPxE1? NV3EOW1rOSCq NX\t[IxIeHKndnXueJMhfGinIFXNRXAuUUlvaX7keYNm\CCWRVXSJJZidHWnIHTlZ5Jm[XOn MYOyOVQyPjZ3MR?=
RBMECs NWLveG9HTnWwY4Tpc44hSXO|YYm= MUi1xsDPxE1? M13uU|EhcA>? MlLkdJJmfmWwdIOgeIhmKGmwY4LlZZNmKGmwIFjSVEBndHW6IHHjdo9{eyC2aHWgRnRDKGmwZIXj[YQh[nliIFXNRXAuUUl? NWjRTXdGOjV2MU[2OVE>
RBMECs NHzlZVhHfW6ldHnvckBCe3OjeR?= NHTOZ|E2yqEQvF2= MV:xJIg> NUDYSXlDcW6qaXLpeJMhfGinIHTlZ5Jm[XOnZDDv[kBidW:3boSgc4YhYk9vMTDpckBOTnNiaX7keYNm\CCkeTDFUWFRNUmL MkXwNlU1OTZ4NUG=
RBMECs MX\GeY5kfGmxbjDBd5NigQ>? MkfwOeKh|ryP M2LvflEhcA>? MXLy[ZZmenOnczD0bIUh[2ijbnfld{BqdiCcTz2xJIRqe3S{aXL1eIlwdiC|ZXXuJJdqfGhiRV3BVE1KUSC2cnXheI1mdnR? Moi3NlU1OTZ4NUG=
RBMECs M3;hWWZ2dmO2aX;uJGF{e2G7 M4DPXFXDqM7:TR?= MnrtNUBp NIW4OXljdG:la4OgeIhmKEWPQWCtTWkucW6mdXPl[EBkcGGwZ3WgbY4hVUyFIIDoc5NxcG:{eXzheIlwdg>? M{\mVlI2PDF4NkWx
RBMECs M1O5bGZ2dmO2aX;uJGF{e2G7 MXG1xsDPxE1? NHH6XJUyKGh? M{jjSYJtd2OtczD0bIUh[WO2aX6gZ5l1d3OtZXzleI9vKHKnYYLyZY5o\W2nboSgd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70xsA> MYmyOVQyPjZ3MR?=
Primary bovine chondrocytes MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mo\JOe69VQ>? MW[0PEBp NXztT3lkemW4ZYLz[ZMhfGinIHnubIljcXSxcomg[YZn\WO2IH;mJINmdGWlb4jpZkBwdiCycn;sbYZmemG2aX;uJIlvKGe{b4f0bEBxdGG2ZTDjbI9v\HKxY4n0[ZM> NHnNTo4zPTRyNkCxOi=>
EM1  Mn7oSpVv[3Srb36gRZN{[Xl? M2T4dFE26oDMzszN M1fEPVQ5KGh? MlT3doVlfWOnczD0bIUh\XiycnXzd4lwdiCxZtMgUGlHyqCxctMgVHRIWzMEoHnuxsBESUyULTDvduKhTVCDQ{Ktd4lt\W6lZXSgSW0yKGOnbHzzxsA> M4PwPVI2Ozd6Nk[x
BeWo  NFfGSlJHfW6ldHnvckBCe3OjeR?= MlXjNlDDqML3TR?= MXe0POKhcMLi M1\TfGROW00EoB?= MnX3bY5kemWjc3XzJJRp\SCkZYThMYhETyC{ZXzlZZNm NWS1fZRoOjV|NkKyOlA>
BeWo  MnLCSpVv[3Srb36gRZN{[Xl? NIrzbpgzOMLiwsXN NFuzWoo1QMLiaNMg Mn3sSG1UV8Li MXnkc5dvemWpdXzheIV{KHSqZTDs[ZZmdCCxZjDUUWVOTjF4 Mni0NlU{PjJ{NkC=
BeWo  NUfPXHdpTnWwY4Tpc44hSXO|YYm= NX3TXZhjOjEEoNM1US=> NInLe4w1QMLiaNMg MU\EUXNQyqB? MoLC[I94dnKnZ4XsZZRmeyC2aHWgcIV3\Wxib3[gS2NONTF? M{XXPFI2OzZ{Mk[w
granulosa cells MU\GeY5kfGmxbjDBd5NigQ>? M4nrc|ExKM7:TR?= MX:xNk8zPCCq NXnadZBZcW6lcnXhd4V{KHSqZTDs[ZZmdHNib3dCpHJIWzMEoH3SUmE> NYi3dINUOjV|M{mxNFU>
granulosa cells NIrPUodHfW6ldHnvckBCe3OjeR?= MUWxNEDPxE1? NX[xXJBDOTJxMkSgbC=> M33BUolv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= M4\rRlI2OzN7MUC1
granulosa cells MkTiSpVv[3Srb36gRZN{[Xl? MVqxNEDPxE1? NH24[FkzPCCq M2[yT4lv[3KnYYPld{B1cGViaX70[Y5{cXS7IH;mJGRPSS:ycn;0[YlvKGOxbYDs[Zg> MWmyOVM{QTFyNR?=
granulosa cells NH\wUGtHfW6ldHnvckBCe3OjeR?= MXyxNEDPxE1? NIfEZ4kzPCCq NE\jblhqdmO{ZXHz[ZMhfGinIHzleoVteyCxZjDSS3MzKHC{b33veIVzKGGldHn2bZR6 NInmdmczPTN|OUGwOS=>
SK-N-AS  NUfwfoxUS2WubDDWbYFjcWyrdImgRZN{[Xl? NUDSS3BPOTBizszNxsA> NITENYMzPC92ODDo M2qxWoVvcGGwY3XzJJRqdWVvZHXw[Y5l\W62bImgZ4VtdHWuYYKgeoli[mmuaYT5xsA> Mle4NlUzPjZyNkO=
SK-N-AS  NYDtTXRETnWwY4Tpc44hSXO|YYm= NXrTe45IOTBizszNxsA> MlPYNlQhcA>? NI\Q[WZqdmO{ZXHz[ZMhfGinIHPBUXAhdGW4ZXzzxsA> M2LlcVI2OjZ4ME[z
SK-N-AS  Mn;2SpVv[3Srb36gRZN{[Xl? MnrWNVAh|ryPwrC= MnrkNlQhcA>? MnrtbY5kemWjc3XzJJRp\SCneIDy[ZN{cW:wIH;mJIN6[2yrbjDENS=> MlG5NlUzPjZyNkO=
SK-N-AS  M3:wcGZ2dmO2aX;uJGF{e2G7 M{HuTFExKM7:TdMg M4GxSVMxKG2rbh?= Mnu4bY5lfWOnczDwbI9{eGixconsZZRqd25ib3[g{tIu[2G2ZX7pckApe2W{Nke1LUwheC2JU1uz{tIhMHOnckmpJIFv\CClb37jc41qfGGwdDDobYdp\XJibHX2[Yx{KG:oIHHjeIl3\SxidX7wbI9{eGixconsZZRm\CxizsKtZ4F1\W6rbh?= NXLjVIR3OjV{Nk[wOlM>
SK-N-AS  MnPuSpVv[3Srb36gRZN{[Xl? NGHP[IQyOCEQvF5CpC=> MkPRNVAwOzBxNkCgcYlv MUjpcoNz\WG|ZYOgcIV3\Wy|IH;mJJAu|rJvY3H0[Y5qdiBqc3XyOlc2MSCjbnSgbY5lfWOnczDhZ4N2dXWuYYTpc44hd2ZicD5Otk1k[XSnbnnuJEh{\XJ4N{WpJIlvKCiyZYLpLY52[2ynYYKgdoVocW:wcx?= MUmyOVI3PjB4Mx?=
SK-N-SH NFH3fo1E\WyuIG\pZYJqdGm2eTDBd5NigQ>? MUSxNEDPxE4EoB?= NEKxWms1QCCq M1nzZ4VvcGGwY3XzJHNMNU5vU1igcoV2em:kbHHzeI9u[SClZXzsJJZq[WKrbHn0fS=> Mn;jNlUzPjZyNkO=
HEK‐CFTR NVPJbox5TnWwY4Tpc44hSXO|YYm= M1vqTFLjiJN3MNMg{txO NHjTbooxNTF{IH3pci=> NVTaRm9STE2VT9Mg MXTpcoR2[2W|IHGg[I9{\eLCkHTldIVv\GWwdDDpc4Rq\GViZX\mcJV5yqB? NI\mOIQzPTJ4M{KwOy=>
L6 NGXBWJlHfW6ldHnvckBCe3OjeR?= MW[0NEDDvU1? NIDXRpgzPCCq NETpcYZqdmirYnn0d{BFVUhzLXnu[JVk\WRiQXv0JIFkfGm4YYTpc44> M3r6U|I2OjR5NUWw
MIN6  NEXD[lFHfW6ldHnvckBCe3OjeR?= Mn\oNVAh|ryPwrC= NXfzPWlFOyCq NVmzRZh4cW6lcnXhd4V{KER|IH3SUmEh\XiycnXzd4lwdg>? M2DLbVI2OjRzMUK0
ventricular cardiomyocytes  NGjCPYtHfW6ldHnvckBCe3OjeR?= MVywMlAyNTFyIN88US=> Mlj0bY5kemWjc3XzJEBkSU2SIHHjZ5VufWyjdHnvci=> NV7YVXZVOjV{MEOxNVM>
ventricular cardiomyocytes  MmG5SpVv[3Srb36gRZN{[Xl? NI[0Om8xNjBzLUGwJO69VQ>? MoG3[ZZwc2W|IHHuJIlvd3S{b4DpZ{Bz\XOyb37z[UAyOjEEsUG1KUBi[m:4ZTDiZZNidCC5aYToJIFvKEWFNUFCpI9nKDJwMjFCuW0> NYqwO4dYOjV{MEOxNVM>
BeWo  M{X4SmZ2dmO2aX;uJGF{e2G7 NV\uXGk5OjBiwsXN M2H2dlQ5KGh? MlnXSG1UV8Li MlW2bY5lfWOnczDj[YxtKG[3c3nvci=> MUCyOVE5PDR5Nx?=
THP-1  MnrsSpVv[3Srb36gRZN{[Xl? MUCxM|ExKM7:TR?= M1S1b|LDqGh? MWPEUXNQyqB? NXHTT2tSe3WycILld5NmeyCPQ2CtNUBxem:mdXP0bY9vyqB? MYqyOVE2PDh6Mh?=
Huh-7 NGfE[IRHfW6ldHnvckBCe3OjeR?= M4\JblAuOjBizszN M4C3XlIhcMLi NVXtcZRXemW|dXz0d{BqdiCjIHTvd4Uu\GWyZX7k[Y51KGmwY4LlZZNmKGmwIHOtUZlkKGW6cILld5Nqd25iYYSgeIhmKHC{b4TlbY4h[W6mIH3SUmEhdGW4ZXzz MWGyOVExQTh|NB?=
C6 NFnTZ|FHfW6ldHnvckBCe3OjeR?= MlvjNVAh|ryPwrC= MXuyNEBucW5? NHryVldqdmO{ZXHz[ZMh[0GPUDDhZ4N2dXWuYYTpc44> NUHUeJB7OjVyNkm0NVc>
SW480 NH\oS5pHfW6ldHnvckBCe3OjeR?= MUi0NOKh|ryP MVK0POKhcA>? NIi3NXFFVVOR NFKx[Hhi[3SrdnH0[ZMhWFB{QR?= MWWyOFk6PzR3MR?=
HT-29  NVfBOWppTnWwY4Tpc44hSXO|YYm= M3vWRVQxyqEQvF2= NXjZbmpzPDkEoHi= MornSG1UVw>? Mn;kZYN1cX[jdHXzJHBROkF? NFzDXo8zPDl7N{S1NS=>
SW480 NUXLW2V6T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MlrTOFDDqM7:TR?= M{HtTFAuPzJiaB?= MV\EUXNQ MXLpcohq[mm2czDj[YxtKGe{b4f0bEB1cW2nIHTldIVv\GWwdHz5 M1jQflI1QTl5NEWx
HT-29  MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NXO1RnJWPDEEoN88US=> M3PpTlAuPzJiaB?= NFLObnJFVVOR NELGdXhqdmirYnn0d{Bk\WyuIHfyc5d1cCC2aX3lJIRmeGWwZHXueIx6 NG\ud5gzPDl7N{S1NS=>
SW480 M{\ycGZ2dmO2aX;uJGF{e2G7 MV20NOKh|ryP NX3LenJGPyCm M2DWTGROW09? MkDJdoVlfWOnczDjc4xwdm:|cHjldoUh\m:{bXH0bY9vKGOjcHHibYxqfHoEoB?= MoDHNlQ6QTd2NUG=
HT-29  M3vVN2Z2dmO2aX;uJGF{e2G7 M17uXFQxyqEQvF2= NVroZlAxPyCm M2D5TGROW09? MkLadoVlfWOnczDjc4xwdm:|cHjldoUh\m:{bXH0bY9vKGOjcHHibYxqfHoEoB?= NEXNR2wzPDl7N{S1NS=>
SW480 NEXmUpNCeG:ydH;zbZMhSXO|YYm= NUnYR5A{PDEEoN88US=> NWXGcGR[PDkEoHi= MljuSG1UVw>? MVHpcoR2[2W|IHHuJIFkfGm4YYTpc44hd2ZiY3HzdIF{\SB|L{e= NWnG[YZKOjR7OUe0OVE>
HT-29  NV;MUVRxSXCxcITvd4l{KEG|c3H5 MlHROFDDqM7:TR?= NGO0VXk1QMLiaB?= NFnMPVdFVVOR NXvaXYxWcW6mdXPld{BidiCjY4TpeoF1cW:wIH;mJINie3Cjc3WgN{84 M1LpfVI1QTl5NEWx
SW480 MnjvRZBweHSxc3nzJGF{e2G7 NVSxfJlYPDEEoN88US=> M2XGZ|Q5yqCq M1vOPGROW09? NWn4bGlCcW6mdXPld{BkcGGwZ3XzJIlvKHSqZTDwbI9{eGixconsZZRqd25ic4TheJV{KG:oIGDQNmEhfGG{Z3X0dy=> MkXDNlQ6QTd2NUG=
HT-29  NVnPT3J6SXCxcITvd4l{KEG|c3H5 MWO0NOKh|ryP MkXMOFjDqGh? NYPHdWVDTE2VTx?= MUTpcoR2[2W|IHPoZY5o\XNiaX6geIhmKHCqb4PwbI9zgWyjdHnvckB{fGG2dYOgc4YhWFB{QTD0ZZJo\XS| M1vJT|I1QTl5NEWx

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
in solvent
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null Not Applicable

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID