Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 Mle4SpVv[3Srb36gRZN{[Xl? Ml7qNVAh|ryP NXm5ZXI5PiCq NFPjZ|dqdmO{ZXHz[ZMheGixc4Doc5J6dGG2aX;uJI9nKG:4ZYLlfJBz\XO|ZXSgT2xJVDNiYYSgV|Q{Ow>? M3LER|I3PDN3NEm4
Mo-DCs NIi2UJhHfW6ldHnvckBCe3OjeR?= NIK1TIU2OCEQvF2= NV21cGdHOjUkgJno NF;UPG5xem:vb4Tld{BKVC1{MzDwdo9lfWO2aX;uJIlvKHSqZTDzeZBmem6jdHHueEBw\iC8eX3vd4FvKHO2aX31cIF1\WRiTX:tSGN{yqB? M1PY[|I3PDF{OUS4
RBMECs  MlHiSpVv[3Srb36gRZN{[Xl? M2DjblXDqM7:TR?= MXSxxsBp M4S4bIJtd2OtczD0bIUhWmGlMTDpcoFkfGm4YYTpc44hcW6mdXPl[EBjgSCHTVHQMWlK M4frTlI3OzV6MEO5
INA-6 NVfM[mxkS2WubDDWbYFjcWyrdImgRZN{[Xl? M1fyZlAuOTByIN88US=> NETSN2k4OuLCiXi= NX3IeWQ3cW6mdXPld{Bk\WyuIHTlZZRpKGSxc3Wg[IVx\W6mZX70cJk> NXfKN3V5OjZ|ME[2NlQ>
OPM-2 MU\D[YxtKF[rYXLpcIl1gSCDc4PhfS=> MVOwMVExOCEQvF2= M3zLZ|cz6oDLaB?= NV\tdYRicW6mdXPld{Bk\WyuIHTlZZRpKGSxc3Wg[IVx\W6mZX70cJk> MVGyOlMxPjZ{NB?=
U266 NGLNdHZE\WyuIG\pZYJqdGm2eTDBd5NigQ>? NV3vW2FYOC1zMECg{txO M1O2e|cz6oDLaB?= M{i3WYlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 MV:yOlMxPjZ{NB?=
H929 M1XOZWNmdGxiVnnhZoltcXS7IFHzd4F6 Ml;CNE0yODBizszN NHzDfmQ4OuLCiXi= NEHuW2dqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> NX\KNGpGOjZ|ME[2NlQ>
RPMI 8226 MnTzR4VtdCCYaXHibYxqfHliQYPzZZk> MVKwMVExOCEQvF2= M1jLfFcz6oDLaB?= M4e4VYlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 NUX2R|NiOjZ|ME[2NlQ>
MDCK  M4\4UmZ2dmO2aX;uJGF{e2G7 M1;iRlExKML3TR?= NHzpcIwzPCCq MoSwSG1UVw>? NVP5ZXd7fXC{ZXf1cIF1\XNidHjlJIV5eHKnc4Ppc44hd2ZiVFfGMe6zOSCjbnSgR3RITsLi MVeyOlIxOjN3Mh?=
MDCK  M{TtNWZ2dmO2aX;uJGF{e2G7 NWXpZ3hmOTBiwsXN M4jue|I1KGh? MlzRSG1UVw>? MXPpcohq[mm2czD0bIUhcW6lcnXhd4VlKGW6cILld5Nqd25ib3[gSm4h[2G3c3XkJIJ6KFSJRj5OtlE> NELUNZgzPjJyMkO1Ni=>
Spinal cords  M2XQcGZ2dmO2aX;uJGF{e2G7 MlfjNeKh|ryP M3jGdlMxKG2rbh?= NWqxSXlXe3SrbYXsZZRmeyClQV3QJIxmfmWucx?= NWHhdGtnOjZzMk[5NlY>
BeWo  M1nvTmZ2dmO2aX;uJGF{e2G7 MVqyOgKBkc7:TR?= NVTnc4Y3OjRxNEivO|IhcA>? NGrmWVdt\WGmczD0c{BidiCrbnPy[YF{\SCrbjD0bIUh\XiycnXzd4lwdiCxZjDveIhmeiCodYPpc44hdWG{a3Xydy=> MWCyOlA2OzV2OR?=
bovine oocytes M1\PcWZ2dmO2aX;uJGF{e2G7 NF\YbFkyODEEoN88US=> M3fwTVEzyqCq MojGbY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCQUGDBJIFv\C:xcjDOVHBEKHSxIIP0bY12dGG2ZTDy[ZN2dXC2aX;uJI9nKG2naX;zbZM> NHvERnkzPjB3MU[xNS=>
Caco-2  MUPGeY5kfGmxbjDBd5NigQ>? Mn:xNE4yNzFxMUCg{txO MUmyNOKhdWmw NV7aU5UxcW6mdXPld{BiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGmwdILhZ4VtdHWuYYKgZ2FOWCCuZY\lcJM> NEH6W2czPjB2OUGwNi=>
Caco-2  NWHkVVdwTnWwY4Tpc44hSXO|YYm= MYWwMlEwOS9zMDFOwG0> NWLhNZFIOjRiaB?= Ml;lbY5kemWjc3XzJG1TWDJicILveIVqdiCuZY\lcC=> M{TLcFI3ODR7MUCy
AML-12  MVPGeY5kfGmxbjDBd5NigQ>? NVrGdXY3OjBizszN NXX5NpQxOyCq MnnEeZBz\We3bHH0[ZMhfGinIIDoc5NxcG:{eXzheIlwdiCuZY\lcJMh[XRiVHjyMVQyOSCjbnSgV4VzNTR7Mx?= NIDPWHQzPjB2OEm4OS=>
AML-12  MUPGeY5kfGmxbjDBd5NigQ>? MXiyNEDPxE1? MUexMVghcA>? NWS0VIZmcW6lcnXhd4V{KGeudXPvd4UheHKxZIXjeIlwdg>? M4[2Z|I3ODR6OUi1
AML-12  MWjGeY5kfGmxbjDBd5NigQ>? NUDjToJrOjBizszN MXqzJIg> M4i4ZpVxNXKnZ4XsZZRme8LiUHfjNYEtyqCSZYDjb{wh[W6mwrDHOpBkyqCvUl7BJIxmfmWucx?= MoL1NlYxPDh7OEW=
AML-12  Ml\4SpVv[3Srb36gRZN{[Xl? M2O4WVIxKM7:TR?= Moj5N{Bp M1HEUolv\HWlZYOgeIhmKGSncHjvd5Bpd3K7bHH0bY9vKG:oIFPSWGMzyqB? NFzhTIYzPjB2OEm4OS=>
RBMECs MX7GeY5kfGmxbjDBd5NigQ>? MWC1xsDPxE1? NUDzUXlUOSCq MXrpcohq[mm2czDFUWFRNUmLLXnu[JVk\WRiaX7hZ5RqfmG2aX;uJI9nKFKjcEJCpC=> MmLYNlYxPDR4NkO=
EndoC-βH1 Mm\USpVv[3Srb36gRZN{[Xl? NIHTWJY2yqEQvF2= MYixJIg> M4fUSJBwfGWwdHnheIV{KGeudXPvd4UucW6mdXPl[EBqdnO3bHnuJJNm[3KndHnvckBqdiC2aHWgdJJme2WwY3Wgc4Yh\2y3Y3;z[S=> MVyyOlAzQDV4Mh?=
EndoC-βH1 MX;GeY5kfGmxbjDBd5NigQ>? NE\IV202yqEQvF2= M2ftNVEhcA>? MlLQcIVi\HNidH:gZUB{fHKxbnegZ2FOWCCrbnPy[YF{\Q>? MWCyOlAzQDV4Mh?=
SH-SY5Y NEXRTodHfW6ldHnvckBCe3OjeR?= NWPnXoRnOzBizszN MUmzNEBucW5? MX\EUXNQ M3zOfJNq\26rZnnjZY51dHliaX7jdoVie2W|IITo[UBi[3SrdnH0bY9vKG:oIGDLRS=> MXWyOlAzPTF|Nx?=
PC-3 NYfZS2VMTnWwY4Tpc44hSXO|YYm= NEKxZVY1OCEEtV2= MkTLNkBp M3PwXGROW09? MWTs[YFleyC2bzDQVFJCKGGldHn2ZZRqd25? M4HrPFI3ODJ|OEO2
PC-3 MUTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NUDRVHZvPDBiwsXN M3HBS|I1NzR6L{eyJIg> MXzEUXNQ NVvse2tR\GWlcnXhd4V{KGOnbHygeoli[mmuaYT5JJRqdWViZHXw[Y5l\W62bIm= Ml61NlYxOjN6M{[=
SCG NF3DVJpHfW6ldHnvckBCe3OjeR?= NH23cIczOCEQvF5CpC=> NHzlbY1FVVOR MX;y[ZZmenOrYnz5JJN2eHC{ZYPz[ZMhUUuYIIfpeIgh[SCLQ{WwJI9nKDJ2LkSg{txO NUi3c4pJOjV7NkKxN|I>
HEK-293 M17EU2Z2dmO2aX;uJGF{e2G7 MYGzOUDPxE4EoB?= NXz5b4hbTE2VTx?= M3jFSolv\HWlZYOgZUBkd26|cHnjeY92eyEkgKzpcoFkfGm4YYTpc47jiJ1ib3[geIhmKEu4Mj6xJIN2enKnboS= Mo\MNlU6PjJzM{K=
SCG NVr5WWx4TnWwY4Tpc44hSXO|YYm= M1G4W|ExOCEQvF5CpC=> NWLJS5FvTE2VTx?= NUTGUYJ4emWmdXPld{B1cGViZYjjbZRi[mmuaYT5JI9nKFOFRzDu[ZVzd26| NH7jVJYzPTl4MkGzNi=>
PCCL3 M1\3NWZ2dmO2aX;uJGF{e2G7 NVvkOVVJOTBiwsXN NUC1U3NHOjRiaB?= NWLGeYJj\W6qYX7j[ZMhTHWReEKgdJJwdW:2ZYKgeJJidnOlcnnweIlwdiCjY4Tpeol1gcLi4pEL NGLufIkzPTl4MEm1Oi=>
3T3-L1 preadipocytes MmD4SpVv[3Srb36gRZN{[Xl? NUWwdVRMOTBizszNxsA> NXrpNZMxOTJiaB?= MlnkbY5lfWOnczDDVmVDKHCqb4PwbI9zgWyjdHnvckBidmRiQz;FRnDPuiCneIDy[ZN{cW:w M3fPVlI2QTJ6MEW4
H295R  NFLxXVJHfW6ldHnvckBCe3OjeR?= MXKxNOKh|ryP M2HvelQ5yqCq NGfxTIFqdmO{ZXHz[ZMhe3Sncn;p[EBu\XSjYn;sbZRmeyCrbjD0bIUh[W6mcn;n[Y4tKG2rbnXyZYxwNSCjbnSg[4x2[2:lb4L0bYNwcWRicHH0bJdigXN? NFnreoIzPTh4OUW1Oi=>
PBMC NHi3ZVNHfW6ldHnvckBCe3OjeR?= MoTPOVDDqM7:TR?= MYiyOOKhcMLi NVLz[I9JcW6qaXLpeJMhfGinIHnuZ5Jm[XOnZDDz[YNz\XSrb36gc4YhXE6IIHnu[JVk\WRiYomgeIhmKESSRR?= M1f4flI2QDZ4MEe5
GLUTag  MoC0SpVv[3Srb36gRZN{[Xl? M1XOflEx6oDLwsXN NF7sdnQxNzJxNDDo MVjzeIlufWyjdHXzJGdNWC1zIIPlZ5JmfGmxbjDjc5Rz\WG2ZXSge4l1cCCLQl3Y M1[1WVI2QDN{NkOx
GLUTag  NGjPZ|JHfW6ldHnvckBCe3OjeR?= NUPpNZNGOTEkgJpCuW0> M{nENVQhcA>? MXHpcoNz\WG|ZYOgeIhmKHCFUlXCJIxmfmWuczD3bZRpKHSqZTDJRm1Z MXmyOVg{OjZ|MR?=
BAECs MWDGeY5kfGmxbjDBd5NigQ>? M3jEW|I2KM7:TR?= Mm[1NlQhcA>? Ml[0[Y5p[W6lZYOgeIhmKGGldHn2ZZRqd25ib3[gVHBCWs7zIHL5JFUh|ryPIILld5ZmemG2cn;sMEBVPEiVLDDvdkA1NVCDUB?= M4DSOFI2Pzl6OEK2
PC12 M{TpW2Z2dmO2aX;uJGF{e2G7 MoHFNlXDqM7:TR?= NWD3NWYzPDhiaB?= NVPQT|JX[WO2aY\heIV{KGODTWC= NGLhT3EzPTd4OUOwOS=>
GH3 MXPGeY5kfGmxbjDBd5NigQ>? M1n0bVHDqM7:TR?= M1\iUlYucA>? MoX4ZZR1\W63YYTld{B1cGViY3;ydoVt[XSrb36gZoV1f2WnbjDQVmwh[W6mIFLtZYwyKGW6cILld5Nqd25? M13WSVI2PzJ5MEG4
GH3 NGj1U3RHfW6ldHnvckBCe3OjeR?= NFrTcW8yyqEQvF2= NUnmWoJSPi2q MWXpcoR2[2W|IGDSUEBidmRiQn3hcFEtKGK3dDDuc5QhS2yxY3usJI1TVkFiZYjwdoV{e2mxbh?= NF34e5ozPTd{N{CxPC=>
BeWo MnuySpVv[3Srb36gRZN{[Xl? NVLL[pBqOTEkgJtOwG3DqA>? MXq3NkBp M1HVe2ROW09? MmXEcYVlcWG2ZYOgRoVYdyClZXzsJIRq\m[ncnXueIlifGmxbh?= NVHweZJsOjV5MUO0NlU>
oocytes NVvCW25GTnWwY4Tpc44hSXO|YYm= MXe1JO69VQ>? MoPPNlQhcA>? MlP2ZZR1\W63YYTld{BzcC2rboP1cIlvKGGldHnvckBwdiCxb3P5eIUhT1[ERDDzbYdvcW[rY3HueIx6yqB? NX;VZVFvOjV5MEe4OVQ>
SC NVm2bZlHTnWwY4Tpc44hSXO|YYm= M{nnZVAvPSEQvF2= MXiyOEBp Mof1cYlucWOtczD0bIUh\W[oZXP0JI9nKGODTWCgZY5idG:pczDvckBQOSCjbnSgUWJRKGW6cILld5Nqd25? NWrLSJFkOjV5MEW4O|Q>
SC MWrGeY5kfGmxbjDBd5NigQ>? Ml7rNE42KM7:TR?= M3m1R|czKGh? MoTkbY5kemWjc3XzJIJwfGhiS4LvfE0zOCCjbnSgU|Eh\XiycnXzd4lwdiCrbjDhfI9vNXKnbHH0[YQhW0O|IHL1eEBwdmy7IFvyc5guOjEEoB?= NI\pT|UzPTdyNUi3OC=>
UACC-647  NYHRdmxITnWwY4Tpc44hSXO|YYm= M4HJWGROW09? NYnBOolodGWjZIOgeI8h[SC{aYPlJIlvKGODTWCgcIV3\Wy|IDjFR|UxyqB;wrCyNE4{QcLizszNLS=> NVnKbXlkOjV5MEOwNlU>
UACC-647  Mo\LSpVv[3Srb36gRZN{[Xl? NF\PRngyOMLizszN M{nFdFE2KG2rbh?= M3TFd2ROW09? Mn\4bY5pcWKrdIOgSXJMKHCqb4PwbI9zgWyjdHnvci=> NXPTdY1wOjV5MEOwNlU>
UACC-647  M1O5O2Z2dmO2aX;uJGF{e2G7 NVq3cHpLOTEEoN88US=> M2DGNVE2KG2rbh?= NVzLVI5pTE2VTx?= NXzxe4RxcW6lcnXhd4V{KGWHRkKgdIhwe3Cqb4L5cIF1cW:wIHzleoVte8Li MnzlNlU4ODNyMkW=
SH-SY5Y  NHrmPWdHfW6ldHnvckBCe3OjeR?= MU[xNOKh|ryP NH3p[5YyyqCqwrC= NVLwcIVLcW6lcnXhd4V{KEyXQzDhZ5Rqfmm2eR?= M2[2[lI2PTl5NEOz
SH-SY5Y  MXTGeY5kfGmxbjDBd5NigQ>? NH3S[HoyOMLizszN MXKxxsBpyqB? NY\XO2ZYcW6lcnXhd4V{KEGJQ{GgcXJPSSCuZY\lcC=> NY[4UnpROjV3OUe0N|M>
hADSCs M3vYXmZ2dmO2aX;uJGF{e2G7 MWG15qCKyrWP M1vvOFMxKG2rbh?= NUTwdJNncW6lcnXhd4V{KGODTWCgcIV3\Wy| MXiyOVU6OTlyOB?=
HEK293  MVrGeY5kfGmxbjDBd5NigQ>? NX7oTYt1PeLCidM1US=> MYCzNEBucW5? NWD3cHVlcW6lcnXhd4V{KGODTWCgcIV3\Wy| NWTxbpZxOjV3OUG5NFg>
3T3-L1 NFLWeVlHfW6ldHnvckBCe3OjeR?= MVuyMlUwPSEQvF2= NGTGXW8zPCCqwrC= M3K4RZNq\26rZnnjZY51dHliZHXjdoVie2W|IFHUS2wheHKxdHXpckBmgHC{ZYPzbY9vKGG2IHHscEBld3OnczD0[ZN1\WR? MoXSNlU2QTB3OUe=
OCI-Ly1  NXfGdWp4TnWwY4Tpc44hSXO|YYm= MkO3OFDDqM7:TR?= NU\nTJFSOcLiaNMg MVLEUXNQ MVPpcoR2[2W|IITo[UBqdmO{ZX3lcpQhd2ZiY1HNVEBkd26lZX70doF1cW:wcx?= M4\Q[FI2PTd4MkKw
OCI-Ly18  MWrGeY5kfGmxbjDBd5NigQ>? MknpOFDDqM7:TR?= MWqxxsBpyqB? MX7EUXNQ Ml7EbY5lfWOnczD0bIUhcW6lcnXt[Y51KG:oIHPBUXAh[2:wY3XueJJifGmxboO= NUTlRYdwOjV3N{[yNlA>
BeWo NU\sW|VbTnWwY4Tpc44hSXO|YYm= M2LjcFIxyqEEtV2= MVS0POKhcA>? M4XkbWROW09? NH2ybnZqdmO{ZXHz[ZMhfGinIHTp[oZmemWwdHnheIlwdiCxZjDC[XdwKGOnbHzz MVOyOVU3Pjd2MB?=
BeWo M{nnfGZ2dmO2aX;uJGF{e2G7 NUjxc2hXOjEEoNM1US=> M4DhbVQ5yqCq NVnxXJR2TE2VTx?= M2iwcIlv[3KnYYPld{B1cGViYXTo[ZNqd25ib3[gWGhRNTFibX;uc4N6fGW| NV7HWXRWOjV3Nk[3OFA>
LNCaP  MVfGeY5kfGmxbjDBd5NigQ>? MXexNOKh|ryP Ml3LNVIhcMLi M{jVOmROW09? MUPpcoR2[2W|IHGg[JJidWG2aXOgbY5kemWjc3Wgc4YhS1KHQkGgZYN1cX[rdIm= NFH2XpUzPTV2OEC5PS=>
ThGCs  MmPJSpVv[3Srb36gRZN{[Xl? M17Y[|Ex6oDMzszN MmHROQKBkmh? NYnjU4hr[XWpbXXueJMhUEmIMVGgcIV3\Wy|IIToZZQhf2W{ZTDzeIlufWyjdHXkJIJ6KEOxQ3yy M3vjdVI2PDN|MEK3
ThGCs  NF34W4RHfW6ldHnvckBCe3OjeR?= NWfLVXNqOTEkgJtOwG0> MYm05qCLcA>? NH3zfFJqdmO{ZXHz[ZMhS2:FbEKtbY5lfWOnZDDFSG4zyqCpZX7lJIV5eHKnc4Ppc44> NFi5ZlAzPTR|M{CyOy=>
ThGCs  NH7EVW5HfW6ldHnvckBCe3OjeR?= NVmzTZdnOTEkgJtOwG0> M2jGUVMhcA>? NYHIU5A6cW6qaXLpeJMhfGinIHXm[oVkfCCxZjDINm8zKG:wIFXEUlIhdVKQQR?= M2T0SFI2PDN|MEK3
RBMECs MoX6SpVv[3Srb36gRZN{[Xl? Ml\oNE4xPS9yLkWvOUDPxE1? MnzGNE4zPSCq MoPDbY5kemWjc3XzJINCVVBiY3;uZ4VvfHKjdHnvci=> NXnlOm97OjV2MU[2OVE>
RBMECs MlnsSpVv[3Srb36gRZN{[Xl? M3i1OVXDqM7:TR?= M1voc|EhcA>? M4j4UYJtd2OtczD0bIUh[WO2aY\heIlwdiCxZjDSbI9CN1KRQ1ugbY5lfWOnZDDifUBGVUGSLVnJ NUT0N3J{OjV2MU[2OVE>
RBMECs MmL3SpVv[3Srb36gRZN{[Xl? NETlN282yqEQvF2= M4TVVVEhcA>? NXryR2VSeHKndnXueJMhfGinIFXNRXAuUUlvaX7keYNm\CCWRVXSJJZidHWnIHTlZ5Jm[XOn NYnYOHc{OjV2MU[2OVE>
RBMECs NX3LOnc4TnWwY4Tpc44hSXO|YYm= MkDZOeKh|ryP MkTnNUBp Mm\ydJJmfmWwdIOgeIhmKGmwY4LlZZNmKGmwIFjSVEBndHW6IHHjdo9{eyC2aHWgRnRDKGmwZIXj[YQh[nliIFXNRXAuUUl? MkjhNlU1OTZ4NUG=
RBMECs NX\oNpRKTnWwY4Tpc44hSXO|YYm= NX;wdpVpPcLizszN NHm3dWQyKGh? MUfpcohq[mm2czD0bIUh\GWlcnXhd4VlKG:oIHHtc5VvfCCxZjDaU{0yKGmwIF3Gd{BqdmS3Y3XkJIJ6KEWPQWCtTWk> MXWyOVQyPjZ3MR?=
RBMECs NFy2copHfW6ldHnvckBCe3OjeR?= MlH1OeKh|ryP MmHyNUBp NYn3[G9KemW4ZYLz[ZMhfGinIHPoZY5o\XNiaX6gXm8uOSCmaYP0doljfXSrb36gd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70 NFnTOG4zPTRzNk[1NS=>
RBMECs NEDDbHpHfW6ldHnvckBCe3OjeR?= MnXOOeKh|ryP NWfFZVdkOSCq MUXicI9kc3NidHjlJGVOSVBvSVmtbY5lfWOnZDDjbIFv\2ViaX6gUWxEKHCqb4PwbI9zgWyjdHnvci=> Mlf6NlU1OTZ4NUG=
RBMECs MVjGeY5kfGmxbjDBd5NigQ>? NHfQVZM2yqEQvF2= M{Xp[|EhcA>? MofTZoxw[2u|IITo[UBi[3SrbjDjfZRwe2unbHX0c44hemWjcoLhcodmdWWwdDDz[YVvKHerdHigSW1CWC2LSTD0doVifG2nboVCpC=> Mlr6NlU1OTZ4NUG=
Primary bovine chondrocytes MoO3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWG1{txO NFLLZ4s1QCCq M3XRTJJmfmW{c3XzJJRp\SCrbnjpZol1d3K7IHXm[oVkfCCxZjDj[Yxm[2:6aXKgc44heHKxbHnm[ZJifGmxbjDpckBoem:5dHigdIxifGViY3jvcoRzd2O7dHXz M{HBT|I2PDB4MEG2
EM1  NEPzXHNHfW6ldHnvckBCe3OjeR?= M4T5OFE26oDMzszN NF\OW2o1QCCq NEXZTVhz\WS3Y3XzJJRp\SCneIDy[ZN{cW:wIH;mxsBNUUcEoH;yxsBRXEeVMtMgbY7DqEODTGKtJI9zyqCHUFHDNk1{cWynbnPl[EBGVTFiY3XscJPDqA>? M3qz[VI2Ozd6Nk[x
BeWo  MlS4SpVv[3Srb36gRZN{[Xl? M2T0VFIxyqEEtV2= MlfmOFjDqGkEoB?= MnjUSG1UV8Li NX\kXnhYcW6lcnXhd4V{KHSqZTDi[ZRiNWiFRzDy[Yxm[XOn NF3JeXozPTN4MkK2NC=>
BeWo  MXnGeY5kfGmxbjDBd5NigQ>? NEXudZUzOMLiwsXN MYm0POKhcMLi Mn3WSG1UV8Li MnPO[I94dnKnZ4XsZZRmeyC2aHWgcIV3\Wxib3[gWG1GVUZzNh?= NWXoNIxZOjV|NkKyOlA>
BeWo  MWjGeY5kfGmxbjDBd5NigQ>? Mli5NlDDqML3TR?= M2j3flQ5yqCqwrC= MUjEUXNQyqB? MkHE[I94dnKnZ4XsZZRmeyC2aHWgcIV3\Wxib3[gS2NONTF? MkXzNlU{PjJ{NkC=
granulosa cells M2DKRWZ2dmO2aX;uJGF{e2G7 MXOxNEDPxE1? NEHVPZQyOi9{NDDo NGTUUpVqdmO{ZXHz[ZMhfGinIHzleoVteyCxZtMgVmdUOsLibWLORS=> MWCyOVM{QTFyNR?=
granulosa cells MXXGeY5kfGmxbjDBd5NigQ>? MWmxNEDPxE1? MmO5NVIwOjRiaB?= M1rySolv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= MX:yOVM{QTFyNR?=
granulosa cells M4TndWZ2dmO2aX;uJGF{e2G7 MnW5NVAh|ryP NETq[HgzPCCq NXroZlJTcW6lcnXhd4V{KHSqZTDpcpRmdnOrdImgc4YhTE6DL4Dyc5RmcW5iY3;tdIxmgA>? MWmyOVM{QTFyNR?=
granulosa cells MkfDSpVv[3Srb36gRZN{[Xl? NX;ZWHAzOTBizszN NFnlS5EzPCCq NVz0bGFYcW6lcnXhd4V{KHSqZTDs[ZZmdHNib3[gVmdUOiCycn;tc5RmeiCjY4Tpeol1gQ>? NETUcY8zPTN|OUGwOS=>
SK-N-AS  MlLRR4VtdCCYaXHibYxqfHliQYPzZZk> NFnYRWkyOCEQvF5CpC=> NITZVG0zPC92ODDo Mlj6[Y5p[W6lZYOgeIlu\S2mZYDlcoRmdnSueTDj[YxtfWyjcjD2bYFjcWyrdIpCpC=> MkmzNlUzPjZyNkO=
SK-N-AS  NW\YcJBpTnWwY4Tpc44hSXO|YYm= NE\VPZIyOCEQvF5CpC=> NWDqeXRXOjRiaB?= MnPQbY5kemWjc3XzJJRp\SClQV3QJIxmfmWuc9Mg MUCyOVI3PjB4Mx?=
SK-N-AS  MljzSpVv[3Srb36gRZN{[Xl? M2XVWFExKM7:TdMg NVvIT2F5OjRiaB?= M1XKUIlv[3KnYYPld{B1cGViZYjwdoV{e2mxbjDv[kBkgWOuaX6gSFE> M1vhTVI2OjZ4ME[z
SK-N-AS  NVn2bJIxTnWwY4Tpc44hSXO|YYm= MVixNEDPxE4EoB?= MlXaN|AhdWmw NYPs[YxjcW6mdXPld{BxcG:|cHjvdplt[XSrb36gc4Yh|rJvY3H0[Y5qdiBqc3XyOlc2MSxicD3HV2s{|rJiKIPldlkqKGGwZDDjc45kd22rdHHueEBpcWeqZYKgcIV3\Wy|IH;mJIFkfGm4ZTygeY5xcG:|cHjvdplt[XSnZDyg{tIu[2G2ZX7pci=> M3XI[lI2OjZ4ME[z
SK-N-AS  M1\KbmZ2dmO2aX;uJGF{e2G7 MkeyNVAh|ryPwrC= NHWzWmcyOC9|MD:2NEBucW5? MYPpcoNz\WG|ZYOgcIV3\Wy|IH;mJJAu|rJvY3H0[Y5qdiBqc3XyOlc2MSCjbnSgbY5lfWOnczDhZ4N2dXWuYYTpc44hd2ZicD5Otk1k[XSnbnnuJEh{\XJ4N{WpJIlvKCiyZYLpLY52[2ynYYKgdoVocW:wcx?= MYiyOVI3PjB4Mx?=
SK-N-SH Mk\6R4VtdCCYaXHibYxqfHliQYPzZZk> MY[xNEDPxE4EoB?= MWW0PEBp MVflcohidmOnczDTT{1PNVOKIH7leZJw[myjc4TvcYEh[2WubDD2bYFjcWyrdIm= M{HMUVI2OjZ4ME[z
HEK‐CFTR NVH3OlZnTnWwY4Tpc44hSXO|YYm= MmH1NwKBmzVywrFOwG0> MYOwMVEzKG2rbh?= MVHEUXNQyqB? Ml7abY5lfWOnczDhJIRwe2YkgKDk[ZBmdmSnboSgbY9lcWSnIHXm[ox2gMLi NGTtbFIzPTJ4M{KwOy=>
L6 MYnGeY5kfGmxbjDBd5NigQ>? NYjoXGZtPDBiwsXN MXGyOEBp MkPRbY5pcWKrdIOgSG1JOS2rbnT1Z4VlKEGtdDDhZ5RqfmG2aX;u NU\zSXBROjV{NEe1OVA>
MIN6  MVLGeY5kfGmxbjDBd5NigQ>? M1zGVVExKM7:TdMg NH7NWFA{KGh? M4\UPYlv[3KnYYPld{BFOyCvUl7BJIV5eHKnc4Ppc44> MV:yOVI1OTF{NB?=
ventricular cardiomyocytes  MVXGeY5kfGmxbjDBd5NigQ>? NHnDdFExNjBzLUGwJO69VQ>? MlrHbY5kemWjc3XzJEBkSU2SIHHjZ5VufWyjdHnvci=> NHXYfpczPTJyM{GxNy=>
ventricular cardiomyocytes  NEjvdZZHfW6ldHnvckBCe3OjeR?= MWGwMlAyNTFyIN88US=> MUDleo9s\XNiYX6gbY5wfHKxcHnjJJJme3CxboPlJFEzOMLzMUWlJIFjd3[nIHLhd4FtKHerdHigZY4hTUN3MNMgc4YhOi5{INM1US=> MluzNlUzODNzMUO=
BeWo  NWfFN2o3TnWwY4Tpc44hSXO|YYm= NXTm[VZQOjBiwsXN M1XyelQ5KGh? MkL0SG1UV8Li NUX3c2dOcW6mdXPld{Bk\WyuIH\1d4lwdg>? NHPpOYkzPTF6NES3Oy=>
THP-1  MkXySpVv[3Srb36gRZN{[Xl? MnzONU8yOCEQvF2= M1nBZlLDqGh? MWrEUXNQyqB? M1jDOZN2eHC{ZYPz[ZMhVUOSLUGgdJJw\HWldHnvcuKh NEHt[pczPTF3NEi4Ni=>
Huh-7 M1;ZV2Z2dmO2aX;uJGF{e2G7 MnTINE0zOCEQvF2= M{LYVlIhcMLi MWLy[ZN2dHS|IHnuJIEh\G:|ZT3k[ZBmdmSnboSgbY5kemWjc3WgbY4h[y2PeXOg[ZhxemW|c3nvckBifCC2aHWgdJJwfGWrbjDhcoQhdVKQQTDs[ZZmdHN? M2PvVVI2OTB7OEO0
C6 M4WxRmZ2dmO2aX;uJGF{e2G7 MWexNEDPxE4EoB?= NES1bIozOCCvaX6= NH7UXFJqdmO{ZXHz[ZMh[0GPUDDhZ4N2dXWuYYTpc44> NX3seYxMOjVyNkm0NVc>
SW480 NEPHfWtHfW6ldHnvckBCe3OjeR?= MVK0NOKh|ryP MWK0POKhcA>? NEO5V4lFVVOR MYHhZ5RqfmG2ZYOgVHAzSQ>? MYiyOFk6PzR3MR?=
HT-29  NX\wT|Z4TnWwY4Tpc44hSXO|YYm= NXnSfHlyPDEEoN88US=> M37INFQ5yqCq MWPEUXNQ M2XMPYFkfGm4YYTld{BRWDKD MUmyOFk6PzR3MR?=
SW480 MkjmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MVS0NOKh|ryP NVjqd|Y4OC15MjDo MnHwSG1UVw>? NH;3NoVqdmirYnn0d{Bk\WyuIHfyc5d1cCC2aX3lJIRmeGWwZHXueIx6 NGfFS3ozPDl7N{S1NS=>
HT-29  M3jVeWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NIf3OGM1OMLizszN M17wWVAuPzJiaB?= M2izfWROW09? M17abYlvcGmkaYTzJINmdGxiZ4Lve5RpKHSrbXWg[IVx\W6mZX70cJk> M4rQNlI1QTl5NEWx
SW480 MXrGeY5kfGmxbjDBd5NigQ>? M2H3S|QxyqEQvF2= MmfyO{Bl NXXpVpNTTE2VTx?= Ml7CdoVlfWOnczDjc4xwdm:|cHjldoUh\m:{bXH0bY9vKGOjcHHibYxqfHoEoB?= M2npdFI1QTl5NEWx
HT-29  MYDGeY5kfGmxbjDBd5NigQ>? NGfFPIw1OMLizszN MlfwO{Bl MoOwSG1UVw>? NV3Ifo5TemWmdXPld{Bkd2yxbn;zdIhmemViZn;ycYF1cW:wIHPhdIFjcWyrdIpCpC=> NGDJR24zPDl7N{S1NS=>
SW480 NUXMe3BqSXCxcITvd4l{KEG|c3H5 NWm0PFFCPDEEoN88US=> Mne2OFjDqGh? MmTYSG1UVw>? NVTUUHh6cW6mdXPld{BidiCjY4TpeoF1cW:wIH;mJINie3Cjc3WgN{84 NGLweVkzPDl7N{S1NS=>
HT-29  NHTMVXlCeG:ydH;zbZMhSXO|YYm= M{TCdlQxyqEQvF2= MkTtOFjDqGh? MmrqSG1UVw>? Mn22bY5lfWOnczDhckBi[3SrdnH0bY9vKG:oIHPhd5Bie2ViMz:3 NUTFcVc4OjR7OUe0OVE>
SW480 MVnBdI9xfG:|aYOgRZN{[Xl? M1HQS|QxyqEQvF2= NYC4TYhDPDkEoHi= NUPWXWJ6TE2VTx?= NI\nTolqdmS3Y3XzJINp[W6pZYOgbY4hfGinIIDoc5NxcG:{eXzheIlwdiC|dHH0eZMhd2ZiUGCyRUB1[XKpZYTz MoDpNlQ6QTd2NUG=
HT-29  M4fnSmFxd3C2b4Ppd{BCe3OjeR?= NELkfJU1OMLizszN M2TlNlQ5yqCq MofUSG1UVw>? MUjpcoR2[2W|IHPoZY5o\XNiaX6geIhmKHCqb4PwbI9zgWyjdHnvckB{fGG2dYOgc4YhWFB{QTD0ZZJo\XS| MWOyOFk6PzR3MR?=

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null --

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID