Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 M{f3N2Z2dmO2aX;uJGF{e2G7 MWKxNEDPxE1? MoTDOkBp MkLSbY5kemWjc3XzJJBpd3OyaH;yfYxifGmxbjDv[kBwfmW{ZYjwdoV{e2WmIFvMTGw{KGG2IGO0N|M> NFvQVJMzPjR|NUS5PC=>
Mo-DCs MUjGeY5kfGmxbjDBd5NigQ>? MVO1NEDPxE1? MV6yOQKBkWh? M3q3XJBzd22xdHXzJGlNNTJ|IIDyc4R2[3Srb36gbY4hfGinIIP1dIVzdmG2YX70JI9nKHq7bX;zZY4he3SrbYXsZZRm\CCPbz3ER5PDqA>? NWrqR2xOOjZ2MUK5OFg>
RBMECs  MWPGeY5kfGmxbjDBd5NigQ>? MUO1xsDPxE1? MkO5NeKhcA>? NEDU[41jdG:la4OgeIhmKFKjY{GgbY5i[3SrdnH0bY9vKGmwZIXj[YQh[nliRV3BVE1KUQ>? MUWyOlM2QDB|OR?=
INA-6 MUDD[YxtKF[rYXLpcIl1gSCDc4PhfS=> NHjEepQxNTFyMDFOwG0> NILjUHg4OuLCiXi= Mki1bY5lfWOnczDj[YxtKGSnYYToJIRwe2ViZHXw[Y5l\W62bIm= M4Xu[lI3OzB4NkK0
OPM-2 MlXjR4VtdCCYaXHibYxqfHliQYPzZZk> NILzZZMxNTFyMDFOwG0> NFHQUJY4OuLCiXi= MYfpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= M4nle|I3OzB4NkK0
U266 MWTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M4TGOFAuOTByIN88US=> NYPqcYxEPzMkgJno MYrpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= MoXVNlY{ODZ4MkS=
H929 MX3D[YxtKF[rYXLpcIl1gSCDc4PhfS=> M{nydVAuOTByIN88US=> Mln2O|LjiImq MUDpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= NF7xUIYzPjNyNk[yOC=>
RPMI 8226 MkTPR4VtdCCYaXHibYxqfHliQYPzZZk> NInINWsxNTFyMDFOwG0> M2Dl[|cz6oDLaB?= NH:2cpJqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> MmnYNlY{ODZ4MkS=
MDCK  NUXC[mpNTnWwY4Tpc44hSXO|YYm= MUKxNEDDvU1? NF3YSo0zPCCq NILje45FVVOR NV36OFJtfXC{ZXf1cIF1\XNidHjlJIV5eHKnc4Ppc44hd2ZiVFfGMe6zOSCjbnSgR3RITsLi MV:yOlIxOjN3Mh?=
MDCK  M1;UcmZ2dmO2aX;uJGF{e2G7 MlvaNVAhyrWP NXn6Ull[OjRiaB?= MV7EUXNQ NIKzc2pqdmirYnn0d{B1cGViaX7jdoVie2WmIHX4dJJme3Orb36gc4YhTk5iY3H1d4VlKGK7IGTHSk3PujF? Ml3nNlYzODJ|NUK=
Spinal cords  NUHDUWNrTnWwY4Tpc44hSXO|YYm= NFfPVXAyyqEQvF2= M1\k[VMxKG2rbh?= NHLTd4h{fGmvdXzheIV{KGODTWCgcIV3\Wy| M3LFdlI3OTJ4OUK2
BeWo  M{j2TGZ2dmO2aX;uJGF{e2G7 MkTDNlXjiIoQvF2= MX[yOE81QC95MjDo NGLxPXZt\WGmczD0c{BidiCrbnPy[YF{\SCrbjD0bIUh\XiycnXzd4lwdiCxZjDveIhmeiCodYPpc44hdWG{a3Xydy=> MYGyOlA2OzV2OR?=
bovine oocytes M3i3e2Z2dmO2aX;uJGF{e2G7 MmPJNVAxyqEQvF2= NGSwZocyOsLiaB?= NWLpelJIcW6qaXLpeJMhfGinIHXm[oVkfCCxZjDOVHBCKGGwZD;vdkBPWFCFIITvJJN1cW23bHH0[UBz\XO3bYD0bY9vKG:oIH3lbY9{cXN? Mlj3NlYxPTF4MUG=
Caco-2  NIr1WIJHfW6ldHnvckBCe3OjeR?= NGH2U2YxNjFxMT:xNEDPxE1? NGX4UJUzOMLibXnu MWHpcoR2[2W|IHGg[I9{\S2mZYDlcoRmdnRiaX7jdoVie2ViaX6gbY51emGlZXzseYxieiClQV3QJIxmfmWucx?= NFjRclIzPjB2OUGwNi=>
Caco-2  NGnu[IdHfW6ldHnvckBCe3OjeR?= NF\me|UxNjFxMT:xNEDPxE1? MXmyOEBp M1viZ4lv[3KnYYPld{BOWlB{IIDyc5RmcW5ibHX2[Yw> MVuyOlA1QTFyMh?=
AML-12  MWrGeY5kfGmxbjDBd5NigQ>? NXLBd3lVOjBizszN NVu5TWx{OyCq NFfKeVN2eHKnZ4XsZZRmeyC2aHWgdIhwe3Cqb4L5cIF1cW:wIHzleoVteyCjdDDUbJIuPDFzIHHu[EBU\XJvNEmz MlfiNlYxPDh7OEW=
AML-12  M4f4[2Z2dmO2aX;uJGF{e2G7 MmnBNlAh|ryP MorQNU05KGh? MUjpcoNz\WG|ZYOg[4x2[2:|ZTDwdo9lfWO2aX;u MlXhNlYxPDh7OEW=
AML-12  NXvWXoo4TnWwY4Tpc44hSXO|YYm= NGXRVpgzOCEQvF2= NH3J[nY{KGh? MWn1dE1z\We3bHH0[ZPDqFCpY{HhMOKhWGWyY3usJIFv\MLiR{\wZ:KhdVKQQTDs[ZZmdHN? MoHwNlYxPDh7OEW=
AML-12  NGTBcVVHfW6ldHnvckBCe3OjeR?= NWnwWGhyOjBizszN M1v2VFMhcA>? MUHpcoR2[2W|IITo[UBl\XCqb4PwbI9zgWyjdHnvckBw\iCFUmTDNuKh Mo\zNlYxPDh7OEW=
RBMECs MVTGeY5kfGmxbjDBd5NigQ>? NXLkbJRqPcLizszN NHfn[2gyKGh? NUjK[5dbcW6qaXLpeJMhTU2DUD3JTU1qdmS3Y3XkJIlv[WO2aY\heIlwdiCxZjDSZZAyyqB? MofpNlYxPDR4NkO=
EndoC-βH1 M4K5XGZ2dmO2aX;uJGF{e2G7 MVy1xsDPxE1? M3TBN|EhcA>? NYjESJY{eG:2ZX70bYF1\XNiZ3z1Z49{\S2rbnT1Z4VlKGmwc4XsbY4he2WlcnX0bY9vKGmwIITo[UBxemW|ZX7j[UBw\iCpbIXjc5Nm NFnMS5AzPjB{OEW2Ni=>
EndoC-βH1 MYDGeY5kfGmxbjDBd5NigQ>? NXLkcpJUPcLizszN M{f6OVEhcA>? MUTs[YFleyC2bzDhJJN1em:wZzDjRW1RKGmwY4LlZZNm Mn3hNlYxOjh3NkK=
SH-SY5Y MUXGeY5kfGmxbjDBd5NigQ>? NYrjbJhPOzBizszN NUf0TVFPOzBibXnu MnfiSG1UVw>? MoXwd4lodmmoaXPhcpRtgSCrbnPy[YF{\XNidHjlJIFkfGm4YYTpc44hd2ZiUFvB MVuyOlAzPTF|Nx?=
PC-3 MWHGeY5kfGmxbjDBd5NigQ>? MV60NEDDvU1? M2jxfFIhcA>? NYiwU2lLTE2VTx?= MXrs[YFleyC2bzDQVFJCKGGldHn2ZZRqd25? NGHLXnEzPjB{M{izOi=>
PC-3 MUTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> M3HsSVQxKML3TR?= MVuyOE81QC95MjDo MYrEUXNQ MX;k[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHlidHnt[UBl\XCnbnTlcpRtgQ>? NUnwe4FVOjZyMkO4N|Y>
SCG NFvRU3dHfW6ldHnvckBCe3OjeR?= MWqyNEDPxE4EoB?= NGfL[IlFVVOR MV7y[ZZmenOrYnz5JJN2eHC{ZYPz[ZMhUUuYIIfpeIgh[SCLQ{WwJI9nKDJ2LkSg{txO MX6yOVk3OjF|Mh?=
HEK-293 NH7Qb4pHfW6ldHnvckBCe3OjeR?= MmD1N|Uh|ryPwrC= MYfEUXNQ MnXZbY5lfWOnczDhJINwdnOyaXP1c5V{KOLCnHnuZYN1cX[jdHnvcwKBpSCxZjD0bIUhU3Z{LkGgZ5VzemWwdB?= MluxNlU6PjJzM{K=
SCG MVHGeY5kfGmxbjDBd5NigQ>? NIfEZYcyODBizszNxsA> MoLhSG1UVw>? NFn6T21z\WS3Y3XzJJRp\SCneHPpeIFjcWyrdImgc4YhW0OJIH7leZJwdnN? M12yfVI2QTZ{MUOy
PCCL3 NUe1eHIzTnWwY4Tpc44hSXO|YYm= NIn6dJgyOCEEtV2= M1rIOFI1KGh? M2XxU4VvcGGwY3XzJGR2V3h{IIDyc41wfGW{IITyZY5{[3KrcITpc44h[WO2aY\peJnDqOLCix?= M{\Td|I2QTZyOUW2
3T3-L1 preadipocytes M{jDcGZ2dmO2aX;uJGF{e2G7 M1TPT|ExKM7:TdMg MXGxNkBp MmPRbY5lfWOnczDDVmVDKHCqb4PwbI9zgWyjdHnvckBidmRiQz;FRnDPuiCneIDy[ZN{cW:w MnzqNlU6OjhyNUi=
H295R  M{HScmZ2dmO2aX;uJGF{e2G7 MUGxNOKh|ryP MXy0POKhcA>? MXPpcoNz\WG|ZYOgd5Rmem:rZDDt[ZRi[m:uaYTld{BqdiC2aHWgZY5lem:pZX6sJI1qdmW{YXzvMUBidmRiZ3z1Z49kd3K2aXPvbYQheGG2aIfhfZM> NXrhU49YOjV6Nkm1OVY>
PBMC NUniW|MzTnWwY4Tpc44hSXO|YYm= M3jlcVUxyqEQvF2= MlXrNlTDqGkEoB?= NWXnelJTcW6qaXLpeJMhfGinIHnuZ5Jm[XOnZDDz[YNz\XSrb36gc4YhXE6IIHnu[JVk\WRiYomgeIhmKESSRR?= NUG2dWk2OjV6Nk[wO|k>
GLUTag  M3rpbGZ2dmO2aX;uJGF{e2G7 NV3ERWtmOTEkgJpCuW0> MnHpNE8zNzRiaB?= Mom1d5RqdXWuYYTld{BIVFBvMTDz[YNz\XSrb36gZ491emWjdHXkJJdqfGhiSVLNXC=> MUmyOVg{OjZ|MR?=
GLUTag  M{nnZmZ2dmO2aX;uJGF{e2G7 NUn6SZp3OTEkgJpCuW0> MljlOEBp MVrpcoNz\WG|ZYOgeIhmKHCFUlXCJIxmfmWuczD3bZRpKHSqZTDJRm1Z NXTYd|MzOjV6M{K2N|E>
BAECs M2rs[mZ2dmO2aX;uJGF{e2G7 NVjrV2xbOjVizszN NEDUNngzPCCq NFT1UJRmdmijbnPld{B1cGViYXP0bZZifGmxbjDv[kBRWEGUzsGgZpkhPSEQvF2gdoV{fmW{YYTyc4wtKFR2SGOsJI9zKDRvUFHQ MkG5NlU4QTh6Mk[=
PC12 M4fBbWZ2dmO2aX;uJGF{e2G7 NWPF[pZOOjYEoN88US=> M{\XNFQ5KGh? MkPOZYN1cX[jdHXzJINCVVB? MYGyOVc3QTNyNR?=
GH3 NUDDR3BDTnWwY4Tpc44hSXO|YYm= MlXLNeKh|ryP NU\ZTHdOPi2q MWPheJRmdnWjdHXzJJRp\SClb4Ly[YxifGmxbjDi[ZR4\WWwIGDSUEBidmRiQn3hcFEh\XiycnXzd4lwdg>? MojLNlU4OjdyMUi=
GH3 M1LGTGZ2dmO2aX;uJGF{e2G7 M{[xflHDqM7:TR?= M2W0WVYucA>? NVHFb3ZycW6mdXPld{BRWkxiYX7kJGJu[WxzLDDieZQhdm:2IFPsc4NsNCCvUl7BJIV5eHKnc4Ppc44> M123NFI2PzJ5MEG4
BeWo M4nLdmZ2dmO2aX;uJGF{e2G7 MW[xNQKBks7:TdMg MWC3NkBp NYHGR5NTTE2VTx?= M33iWY1m\GmjdHXzJGJmX29iY3XscEBlcW[oZYLlcpRq[XSrb36= M2jVNVI2PzF|NEK1
oocytes NVfsTVhuTnWwY4Tpc44hSXO|YYm= NV75W241PSEQvF2= NFHEemUzPCCq NFLKdYVifHSnboXheIV{KHKqLXnud5VtcW5iYXP0bY9vKG:wIH;vZ5l1\SCJVlLEJJNq\26rZnnjZY51dHoEoB?= M3KwdFI2PzB5OEW0
SC MXrGeY5kfGmxbjDBd5NigQ>? NEXvdHAxNjVizszN NXnMOplvOjRiaB?= M4Xh[41qdWmla4OgeIhmKGWoZnXjeEBw\iClQV3QJIFv[WyxZ4Ogc44hVzFiYX7kJG1DWCCneIDy[ZN{cW:w M3nOOlI2PzB3OEe0
SC M3XoNmZ2dmO2aX;uJGF{e2G7 MlzmNE42KM7:TR?= Mmn3O|IhcA>? M2DPXolv[3KnYYPld{Bjd3SqIFvyc5guOjBiYX7kJG8yKGW6cILld5Nqd25iaX6gZZhwdi2{ZXzheIVlKFOFczDieZQhd26ueTDLdo95NTJywrC= MmTtNlU4ODV6N{S=
UACC-647  NYTG[Y5rTnWwY4Tpc44hSXO|YYm= M2XCN2ROW09? MX;s[YFleyC2bzDhJJJqe2ViaX6gZ2FOWCCuZY\lcJMhMEWFNUFCpF3DqDJyLkO5xsDPxE1r MXGyOVcxOzB{NR?=
UACC-647  M{T0WWZ2dmO2aX;uJGF{e2G7 NWPWbHU3OTEEoN88US=> NHzwcJYyPSCvaX6= M2j1VWROW09? Moe3bY5pcWKrdIOgSXJMKHCqb4PwbI9zgWyjdHnvci=> MV6yOVcxOzB{NR?=
UACC-647  MYfGeY5kfGmxbjDBd5NigQ>? MW[xNOKh|ryP MmrVNVUhdWmw MXzEUXNQ NF\HUWRqdmO{ZXHz[ZMh\UWIMjDwbI9{eGixconsZZRqd25ibHX2[Yx{yqB? M2XOSVI2PzB|MEK1
SH-SY5Y  NVLNOlNXTnWwY4Tpc44hSXO|YYm= NE\ldVUyOMLizszN MWexxsBpyqB? MW\pcoNz\WG|ZYOgUHVEKGGldHn2bZR6 NWrlWnZ1OjV3OUe0N|M>
SH-SY5Y  Ml:3SpVv[3Srb36gRZN{[Xl? MVOxNOKh|ryP NUDOOIxyOcLiaNMg NFHYUG1qdmO{ZXHz[ZMhSUeFMTDtVm5CKGyndnXs MUSyOVU6PzR|Mx?=
hADSCs M37rTGZ2dmO2aX;uJGF{e2G7 MlvQOgKBkcL3TR?= NHHwU3M{OCCvaX6= NUjDVWV[cW6lcnXhd4V{KGODTWCgcIV3\Wy| Mk\4NlU2QTF7MEi=
HEK293  M3vEWmZ2dmO2aX;uJGF{e2G7 MnPrOgKBkcL3TR?= M4DaRlMxKG2rbh?= MWrpcoNz\WG|ZYOgZ2FOWCCuZY\lcJM> M1q4d|I2PTlzOUC4
3T3-L1 MkfUSpVv[3Srb36gRZN{[Xl? NXvqblNTOi53L{Wg{txO MUWyOEBpyqB? NFf1SnB{cWewaX\pZ4FvfGy7IHTlZ5Jm[XOnczDBWGdNKHC{b4TlbY4h\XiycnXzd4lwdiCjdDDhcIwh\G:|ZYOgeIV{fGWm MYiyOVU6ODV7Nx?=
OCI-Ly1  NVXoeYh[TnWwY4Tpc44hSXO|YYm= NXPsUmR1PDEEoN88US=> NETKZpEyyqCqwrC= MkXzSG1UVw>? M{LIXIlv\HWlZYOgeIhmKGmwY4LlcYVvfCCxZjDjRW1RKGOxbnPlcpRz[XSrb37z NInGZYszPTV5NkKyNC=>
OCI-Ly18  NUnJdHlMTnWwY4Tpc44hSXO|YYm= MmXtOFDDqM7:TR?= MVWxxsBpyqB? MkS5SG1UVw>? MoO0bY5lfWOnczD0bIUhcW6lcnXt[Y51KG:oIHPBUXAh[2:wY3XueJJifGmxboO= M4LZdFI2PTd4MkKw
BeWo M1XXUGZ2dmO2aX;uJGF{e2G7 MkHaNlDDqML3TR?= NFPtT281QMLiaB?= NX\iOGZ5TE2VTx?= NILrdZFqdmO{ZXHz[ZMhfGinIHTp[oZmemWwdHnheIlwdiCxZjDC[XdwKGOnbHzz MlPTNlU2PjZ5NEC=
BeWo M3qzSGZ2dmO2aX;uJGF{e2G7 MWWyNOKhyrWP MmO0OFjDqGh? Mki3SG1UVw>? MUHpcoNz\WG|ZYOgeIhmKGGmaHXzbY9vKG:oIGTIVE0yKG2xbn;jfZRmew>? MUWyOVU3Pjd2MB?=
LNCaP  NUfLOZpqTnWwY4Tpc44hSXO|YYm= MmLjNVDDqM7:TR?= NWrLbJpYOTJiaNMg MoXLSG1UVw>? MUTpcoR2[2W|IHGg[JJidWG2aXOgbY5kemWjc3Wgc4YhS1KHQkGgZYN1cX[rdIm= MVqyOVU1QDB7OR?=
ThGCs  NUPyfGU2TnWwY4Tpc44hSXO|YYm= NH;XTIoyOOLCit88US=> Mnn2OQKBkmh? NH;rOGpifWevZX70d{BJUUZzQTDs[ZZmdHNidHjheEB4\XKnIIP0bY12dGG2ZXSgZpkhS2:FbEK= Mnz0NlU1OzNyMke=
ThGCs  NHTTcGdHfW6ldHnvckBCe3OjeR?= M3jybVEx6oDMzszN M2fVdFTjiIqq Mlf2bY5kemWjc3XzJGNwS2x{LXnu[JVk\WRiRVTONuKh\2WwZTDlfJBz\XO|aX;u MXSyOVQ{OzB{Nx?=
ThGCs  Mom3SpVv[3Srb36gRZN{[Xl? NGXKV|kyOOLCit88US=> MmrTN{Bp Mk\2bY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCKMl:yJI9vKEWGTkKgcXJPSQ>? MWOyOVQ{OzB{Nx?=
RBMECs M1jqdGZ2dmO2aX;uJGF{e2G7 NETUNo4xNjB3L{CuOU82KM7:TR?= MnjENE4zPSCq M2PtZolv[3KnYYPld{BkSU2SIHPvcoNmdnS{YYTpc44> M1rXZVI2PDF4NkWx
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RBMECs NX75V4l4TnWwY4Tpc44hSXO|YYm= Mly5OeKh|ryP MYexJIg> NVix[4F3emW4ZYLz[ZMhfGinIHPoZY5o\XNiaX6gXm8uOSCmaYP0doljfXSrb36gd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70 NWK4coNnOjV2MU[2OVE>
RBMECs NULFcGJzTnWwY4Tpc44hSXO|YYm= NHPLVpY2yqEQvF2= Mlv5NUBp NEDv[phjdG:la4OgeIhmKEWPQWCtTWkucW6mdXPl[EBkcGGwZ3WgbY4hVUyFIIDoc5NxcG:{eXzheIlwdg>? NU\3OHZZOjV2MU[2OVE>
RBMECs NETG[3pHfW6ldHnvckBCe3OjeR?= NXHuVnZtPcLizszN NFrkWnQyKGh? M17UPIJtd2OtczD0bIUh[WO2aX6gZ5l1d3OtZXzleI9vKHKnYYLyZY5o\W2nboSgd4VmdiC5aYToJGVOSVBvSVmgeJJm[XSvZX70xsA> M3XtTlI2PDF4NkWx
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EM1  MnGwSpVv[3Srb36gRZN{[Xl? M{DxNFE26oDMzszN MWO0PEBp M17WSpJm\HWlZYOgeIhmKGW6cILld5Nqd25ib3dCpGxKTsLib4NCpHBVT1N{wrDpcuKhS0GOUj2gc5LDqEWSQVOyMZNqdGWwY3XkJGVOOSClZXzsd:Kh M2W2d|I2Ozd6Nk[x
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BeWo  NVrONVVHTnWwY4Tpc44hSXO|YYm= NETEb4ozOMLiwsXN M3vsclQ5yqCqwrC= M1nXOWROW00EoB?= NIi1flhld3ewcnXneYxifGW|IITo[UBt\X[nbDDv[kBIS01vMR?= NFPTNYozPTN4MkK2NC=>
granulosa cells NUWxdZVITnWwY4Tpc44hSXO|YYm= MlLnNVAh|ryP MmL6NVIwOjRiaB?= NVXTU4xVcW6lcnXhd4V{KHSqZTDs[ZZmdHNib3dCpHJIWzMEoH3SUmE> MXOyOVM{QTFyNR?=
granulosa cells NEX1fGlHfW6ldHnvckBCe3OjeR?= MXuxNEDPxE1? MnfoNVIwOjRiaB?= M33UPIlv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= NE\m[|gzPTN|OUGwOS=>
granulosa cells NYPjUIlpTnWwY4Tpc44hSXO|YYm= MU[xNEDPxE1? M{G2U|I1KGh? NXn6SWJlcW6lcnXhd4V{KHSqZTDpcpRmdnOrdImgc4YhTE6DL4Dyc5RmcW5iY3;tdIxmgA>? MoDoNlU{OzlzMEW=
granulosa cells M3XXbGZ2dmO2aX;uJGF{e2G7 MnrwNVAh|ryP NIjlSlIzPCCq MoPkbY5kemWjc3XzJJRp\SCuZY\lcJMhd2ZiUlfTNkBxem:vb4TldkBi[3Srdnn0fS=> MkXiNlU{OzlzMEW=
SK-N-AS  M2nMUWNmdGxiVnnhZoltcXS7IFHzd4F6 NVvGcGRXOTBizszNxsA> NXGwVJI1OjRxNEigbC=> NXizOoZp\W6qYX7j[ZMhfGmvZT3k[ZBmdmSnboTsfUBk\WyudXzhdkB3cWGkaXzpeJnDqA>? M2fGSlI2OjZ4ME[z
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SK-N-AS  MULGeY5kfGmxbjDBd5NigQ>? M{PGdFExKM7:TdMg MoD5NVAwOzBxNkCgcYlv M4m3WYlv[3KnYYPld{Bt\X[nbIOgc4YheC4Qsj3jZZRmdmmwIDjz[ZI3PzVrIHHu[EBqdmS3Y3XzJIFk[3WvdXzheIlwdiCxZjDwMe6zNWOjdHXubY4hMHOnck[3OUkhcW5iKIDldokqdnWlbHXhdkBz\Werb37z NHO5[|UzPTJ4NkC2Ny=>
SK-N-SH MX\D[YxtKF[rYXLpcIl1gSCDc4PhfS=> NGfRT2UyOCEQvF5CpC=> M1LCeFQ5KGh? M4\zVoVvcGGwY3XzJHNMNU5vU1igcoV2em:kbHHzeI9u[SClZXzsJJZq[WKrbHn0fS=> NUHjdYZ4OjV{Nk[wOlM>
HEK‐CFTR MXrGeY5kfGmxbjDBd5NigQ>? NXTsZ4tWOuLCk{WwxsDPxE1? NE\w[|UxNTF{IH3pci=> M{nnU2ROW00EoB?= NXmyNYdGcW6mdXPld{BiKGSxc3ZihLBl\XCnbnTlcpQhcW:maXTlJIVn\my3eNMg NUC0[IRUOjV{NkOyNFc>
L6 NYrRTVg1TnWwY4Tpc44hSXO|YYm= MV[0NEDDvU1? NWr4UppWOjRiaB?= NF30cpFqdmirYnn0d{BFVUhzLXnu[JVk\WRiQXv0JIFkfGm4YYTpc44> MnTqNlUzPDd3NUC=
MIN6  M3\0fWZ2dmO2aX;uJGF{e2G7 M1;rcVExKM7:TdMg MW[zJIg> NITi[|dqdmO{ZXHz[ZMhTDNibWLORUBmgHC{ZYPzbY9v M4fKd|I2OjRzMUK0
ventricular cardiomyocytes  NIrCUJFHfW6ldHnvckBCe3OjeR?= NYnPPFRGOC5yMT2xNEDPxE1? M33lZ4lv[3KnYYPld{Ah[0GPUDDhZ4N2dXWuYYTpc44> NXTFNFZNOjV{MEOxNVM>
ventricular cardiomyocytes  NEHyVmpHfW6ldHnvckBCe3OjeR?= MkHZNE4xOS1zMDFOwG0> M3u2UoV3d2unczDhckBqdm:2cn;wbYMhemW|cH;ud4UhOTJywsGxOUUh[WKxdnWgZoF{[Wxid3n0bEBidiCHQ{WwxsBw\iB{LkKgxtVO MkjRNlUzODNzMUO=
BeWo  MW\GeY5kfGmxbjDBd5NigQ>? Mn;MNlAhyrWP NX21d2psPDhiaB?= MYPEUXNQyqB? Mnz5bY5lfWOnczDj[YxtKG[3c3nvci=> M33tTVI2OTh2NEe3
THP-1  MnXUSpVv[3Srb36gRZN{[Xl? MYWxM|ExKM7:TR?= MXKyxsBp NXfZNpJQTE2VT9Mg MnHGd5VxeHKnc4Pld{BOS1BvMTDwdo9lfWO2aX;uxsA> MkP0NlUyPTR6OEK=
Huh-7 MoPYSpVv[3Srb36gRZN{[Xl? MnrlNE0zOCEQvF2= M4LDXlIhcMLi NX\meHdsemW|dXz0d{BqdiCjIHTvd4Uu\GWyZX7k[Y51KGmwY4LlZZNmKGmwIHOtUZlkKGW6cILld5Nqd25iYYSgeIhmKHC{b4TlbY4h[W6mIH3SUmEhdGW4ZXzz NXTJWmo5OjVzMEm4N|Q>
C6 MonCSpVv[3Srb36gRZN{[Xl? NY[zb|FNOTBizszNxsA> NFzPRpMzOCCvaX6= MnvCbY5kemWjc3XzJINCVVBiYXPjeY12dGG2aX;u NFHlfVYzPTB4OUSxOy=>
SW480 M2rueGZ2dmO2aX;uJGF{e2G7 MkjTOFDDqM7:TR?= MV60POKhcA>? NE[yPFFFVVOR MWHhZ5RqfmG2ZYOgVHAzSQ>? NXvROGxsOjR7OUe0OVE>
HT-29  M3r0VmZ2dmO2aX;uJGF{e2G7 NI\kWIQ1OMLizszN NG\LZ4s1QMLiaB?= MlThSG1UVw>? M2TsV4FkfGm4YYTld{BRWDKD MUCyOFk6PzR3MR?=
SW480 M1TNZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVq0NOKh|ryP NWexb491OC15MjDo NGTxbXBFVVOR M3jGUIlvcGmkaYTzJINmdGxiZ4Lve5RpKHSrbXWg[IVx\W6mZX70cJk> M1;YeVI1QTl5NEWx
HT-29  NUnxSHVIT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NUXaZXJPPDEEoN88US=> NHfzN|ExNTd{IHi= MlzWSG1UVw>? MonMbY5pcWKrdIOgZ4VtdCCpcn;3eIghfGmvZTDk[ZBmdmSnboTsfS=> NHPTelAzPDl7N{S1NS=>
SW480 NFfjd5dHfW6ldHnvckBCe3OjeR?= M2[0TlQxyqEQvF2= NEX2N5o4KGR? M4rMeGROW09? NFnH[FBz\WS3Y3XzJINwdG:wb4PwbIVz\SCob4LtZZRqd25iY3HwZYJqdGm2edMg M3fHdFI1QTl5NEWx
HT-29  NFiye2ZHfW6ldHnvckBCe3OjeR?= M3XxWlQxyqEQvF2= MnXNO{Bl MUDEUXNQ MYDy[YR2[2W|IHPvcI9vd3OyaHXy[UBnd3KvYYTpc44h[2GyYXLpcIl1gcLi NIDEN20zPDl7N{S1NS=>
SW480 MmfORZBweHSxc3nzJGF{e2G7 NFzHbo41OMLizszN M3mzNFQ5yqCq M{TsTGROW09? MXvpcoR2[2W|IHHuJIFkfGm4YYTpc44hd2ZiY3HzdIF{\SB|L{e= Mlv3NlQ6QTd2NUG=
HT-29  M{TW[WFxd3C2b4Ppd{BCe3OjeR?= NUDTPWNSPDEEoN88US=> M1fjNlQ5yqCq NG\ITYNFVVOR M4TsRolv\HWlZYOgZY4h[WO2aY\heIlwdiCxZjDjZZNx[XOnIEOvOy=> M2jYWlI1QTl5NEWx
SW480 MYnBdI9xfG:|aYOgRZN{[Xl? M{LVZlQxyqEQvF2= M4jWUVQ5yqCq NYjBRVVQTE2VTx?= MonybY5lfWOnczDjbIFv\2W|IHnuJJRp\SCyaH;zdIhwenmuYYTpc44he3SjdIXzJI9nKFCSMlGgeIFz\2W2cx?= M1HQTFI1QTl5NEWx
HT-29  NYXCdplMSXCxcITvd4l{KEG|c3H5 MXW0NOKh|ryP MYm0POKhcA>? NYX3XnJpTE2VTx?= MXzpcoR2[2W|IHPoZY5o\XNiaX6geIhmKHCqb4PwbI9zgWyjdHnvckB{fGG2dYOgc4YhWFB{QTD0ZZJo\XS| NUX5XINGOjR7OUe0OVE>

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null --

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID