Forskolin

目录号:S2449 别名: Coleonol

Forskolin Chemical Structure

Molecular Weight(MW): 410.5

Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。

规格 价格 库存 购买数量  
RMB 1144.16 现货
RMB 903.37 现货
RMB 2229.31 现货
RMB 3029.97 现货
RMB 4679.71 现货
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客户使用该产品的2个实验数据:

  • Eur J Cancer 2014 50(7), 1310-20. Forskolin purchased from Selleck.

    Measurement of cAMP accumulation in INS-1 cells. (A) INS-1, or (B) INS-1 transfected with murine GPR109A for 24 h, or (C) INS-1 transfected with human GPR109A for 24 h were incubated in DMEM (2.5 mM glucose) media with or without PTX (100 ng/ml) for 24 h. Cells were then incubated in KRB supplemented with 2.5 mM glucose, 500 μM IBMX, 10 μM forskolin, and with/without 10 or 100 μM NA for 1 h. After lysis with HCl (0.1 M), cells were sonicated and spun. The supernatants were saved for cAMP measurement by ELISA. (D) Reduction of cAMP accumulation in INS-1 and INS-1 cells transfected with GPR109A in the presence of 10 or 100 μM NA. White bar: INS-1 cells, grey bar: INS-1 cells transfected with murine GPR109A; black bar: INS-1 cells transfected with human GPR109A. (∗ and #p < 0.05, ∗ and ##p < 0.001). (n = 5).

    Gen Comp Endocrinol, 2016, 237:98-108. Forskolin purchased from Selleck.

产品安全说明书

cAMP抑制剂选择性比较

生物活性

产品描述 Forskolin在各种各样细胞类型中,是一种普遍存在的真核细胞腺苷酸环化酶(AC)激活剂,在细胞生理学研究中,通常用来提高cAMP水平。
靶点
Adenylyl cyclase (AC) [1]
(A wide variety of cell types)
体外研究

Forskolin可以使膜,细胞或组织制备液中cAMP含量上升。Forskolin 不仅可以活化AC 而且可以与某些其它蛋白相互作用,包括葡萄糖转运蛋白和离子通道。Forskolin能够促进9种不同独立AC形式的活化,虽然对AC9效率有点低,这可以用于提供一种鉴定和量化G蛋白 (Gs)–AC复合物高亲和性结合位点的方法。G蛋白偶联受体活化G蛋白有助于细胞中Forskolin刺激的cAMP 产生,因为 G蛋白-Forskolin对AC活性有增强作用[1]。Forskolin在不与细胞表面受体相互作用前提下刺激腺苷酸环化酶活性。在脂肪细胞中Forskolin's促进 cAMP产生进而可以抑制嗜碱性粒细胞和肥大细胞脱颗粒作用以及组胺释放,降低血压、眼内压,抑制血小板聚集,促进血管舒张,支气管扩张和甲状腺激素分泌,刺激脂肪分解。Forskolin 抑制血小板活化因子 (PAF)的结合, 这种抑制不依赖于cAMP形成可能是 Forskolin's 直接作用于 PAF或者通过干扰PAF与它的受体结合实现的。Forskolin似乎对多种膜转运蛋白也有效果并且可以抑制脂肪细胞,红细胞,血小板,和其他细胞中的葡萄糖运输。Forskolin也被用于治疗青光眼[2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
HEK293 NHfVfVFHfW6ldHnvckBCe3OjeR?= MWGxNEDPxE1? NVvZNldKPiCq MkXBbY5kemWjc3XzJJBpd3OyaH;yfYxifGmxbjDv[kBwfmW{ZYjwdoV{e2WmIFvMTGw{KGG2IGO0N|M> NVzxR5FYOjZ2M{W0PVg>
Mo-DCs MWjGeY5kfGmxbjDBd5NigQ>? MWm1NEDPxE1? NGWwOGozPOLCiXi= NVjDOnR[eHKxbX;0[ZMhUUxvMkOgdJJw\HWldHnvckBqdiC2aHWgd5Vx\XKwYYThcpQhd2Zieontc5NidiC|dHnteYxifGWmIF3vMWREe8Li NY\VZY5bOjZ2MUK5OFg>
RBMECs  MX\GeY5kfGmxbjDBd5NigQ>? Mly0OeKh|ryP NWj4fnJ5OcLiaB?= M2fDNIJtd2OtczD0bIUhWmGlMTDpcoFkfGm4YYTpc44hcW6mdXPl[EBjgSCHTVHQMWlK Mkm1NlY{PThyM{m=
INA-6 MYTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MkC3NE0yODBizszN NWTreVZzPzMkgJno MXTpcoR2[2W|IHPlcIwh\GWjdHig[I9{\SCmZYDlcoRmdnSueR?= NWX4fI9OOjZ|ME[2NlQ>
OPM-2 MVTD[YxtKF[rYXLpcIl1gSCDc4PhfS=> MVuwMVExOCEQvF2= NWLoU2F1PzMkgJno NEe2PYRqdmS3Y3XzJINmdGxiZHXheIgh\G:|ZTDk[ZBmdmSnboTsfS=> MUWyOlMxPjZ{NB?=
U266 M3nOXWNmdGxiVnnhZoltcXS7IFHzd4F6 NH21TGcxNTFyMDFOwG0> MkjUO|LjiImq MkflbY5lfWOnczDj[YxtKGSnYYToJIRwe2ViZHXw[Y5l\W62bIm= NWj4ZpQ1OjZ|ME[2NlQ>
H929 NYTnSYhVS2WubDDWbYFjcWyrdImgRZN{[Xl? M1S4bVAuOTByIN88US=> NHrSRVE4OuLCiXi= M3Tvfolv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 NIftVmEzPjNyNk[yOC=>
RPMI 8226 M1rUWmNmdGxiVnnhZoltcXS7IFHzd4F6 MmHQNE0yODBizszN MWe3NwKBkWh? M3LEOIlv\HWlZYOgZ4VtdCCmZXH0bEBld3OnIHTldIVv\GWwdHz5 MX6yOlMxPjZ{NB?=
MDCK  NH7Yc|RHfW6ldHnvckBCe3OjeR?= MnriNVAhyrWP MVqyOEBp NXrkWm1WTE2VTx?= MXr1dJJm\3WuYYTld{B1cGViZYjwdoV{e2mxbjDv[kBVT0ZvzsKxJIFv\CCFVFfGxsA> M4LFbFI3OjB{M{Wy
MDCK  MVPGeY5kfGmxbjDBd5NigQ>? NWHaR2xtOTBiwsXN MlXJNlQhcA>? NXn5emczTE2VTx?= NIK2PINqdmirYnn0d{B1cGViaX7jdoVie2WmIHX4dJJme3Orb36gc4YhTk5iY3H1d4VlKGK7IGTHSk3PujF? M1TsO|I3OjB{M{Wy
Spinal cords  M{HtcmZ2dmO2aX;uJGF{e2G7 NUnpTW17OcLizszN NHXRc2M{OCCvaX6= NF\nd3N{fGmvdXzheIV{KGODTWCgcIV3\Wy| NIO5enkzPjF{NkmyOi=>
BeWo  MmHISpVv[3Srb36gRZN{[Xl? MkfPNlXjiIoQvF2= NUmwN4RoOjRxNEivO|IhcA>? Ml3YcIVi\HNidH:gZY4hcW6lcnXhd4UhcW5idHjlJIV5eHKnc4Ppc44hd2Zib4To[ZIh\nW|aX;uJI1iemuncoO= MnLENlYxPTN3NEm=
bovine oocytes M4P0PWZ2dmO2aX;uJGF{e2G7 M3n3eFExOMLizszN M3\F[FEzyqCq Ml\VbY5pcWKrdIOgeIhmKGWoZnXjeEBw\iCQUGDBJIFv\C:xcjDOVHBEKHSxIIP0bY12dGG2ZTDy[ZN2dXC2aX;uJI9nKG2naX;zbZM> M3\NTlI3ODVzNkGx
Caco-2  MVjGeY5kfGmxbjDBd5NigQ>? MV:wMlEwOS9zMDFOwG0> MWGyNOKhdWmw NUjsSVdScW6mdXPld{BiKGSxc3Wt[IVx\W6mZX70JIlv[3KnYYPlJIlvKGmwdILhZ4VtdHWuYYKgZ2FOWCCuZY\lcJM> NXX6SlFIOjZyNEmxNFI>
Caco-2  M3naRWZ2dmO2aX;uJGF{e2G7 NHzk[oExNjFxMT:xNEDPxE1? MYKyOEBp NXjvUY5JcW6lcnXhd4V{KE2UUEKgdJJwfGWrbjDs[ZZmdA>? NFzZ[3QzPjB2OUGwNi=>
AML-12  M3HGTmZ2dmO2aX;uJGF{e2G7 Mmq5NlAh|ryP NV;4eXhbOyCq MV\1dJJm\3WuYYTld{B1cGVicHjvd5Bpd3K7bHH0bY9vKGyndnXsd{BifCCWaIKtOFEyKGGwZDDT[ZIuPDl| NVjndnFZOjZyNEi5PFU>
AML-12  MVTGeY5kfGmxbjDBd5NigQ>? NIfkV4kzOCEQvF2= MonUNU05KGh? NF76N4dqdmO{ZXHz[ZMh\2y3Y3;z[UBxem:mdXP0bY9v MlTxNlYxPDh7OEW=
AML-12  NIXLcZBHfW6ldHnvckBCe3OjeR?= NX;SO3luOjBizszN NIe1TZk{KGh? NGDjPJN2eC2{ZXf1cIF1\XQEoGDnZ|FiNMLiUHXwZ4stKGGwZNMgS|Zx[8LibWLORUBt\X[nbIO= Ml3kNlYxPDh7OEW=
AML-12  NFTrXFFHfW6ldHnvckBCe3OjeR?= NGPVS2szOCEQvF2= M3zE[VMhcA>? M2rQeIlv\HWlZYOgeIhmKGSncHjvd5Bpd3K7bHH0bY9vKG:oIFPSWGMzyqB? MXWyOlA1QDl6NR?=
RBMECs Ml;NSpVv[3Srb36gRZN{[Xl? Mn;rOeKh|ryP NX3vTJhnOSCq MXTpcohq[mm2czDFUWFRNUmLLXnu[JVk\WRiaX7hZ5RqfmG2aX;uJI9nKFKjcEJCpC=> M{XqXFI3ODR2Nk[z
EndoC-βH1 Mn7HSpVv[3Srb36gRZN{[Xl? Mn\ZOeKh|ryP MXGxJIg> MnfYdI91\W62aXH0[ZMh\2y3Y3;z[U1qdmS3Y3XkJIlve3WuaX6gd4VkemW2aX;uJIlvKHSqZTDwdoV{\W6lZTDv[kBodHWlb4Pl NUOycFhGOjZyMki1OlI>
EndoC-βH1 NIrVe3BHfW6ldHnvckBCe3OjeR?= MX61xsDPxE1? MVKxJIg> MUns[YFleyC2bzDhJJN1em:wZzDjRW1RKGmwY4LlZZNm NUizPIF7OjZyMki1OlI>
SH-SY5Y M2LiXWZ2dmO2aX;uJGF{e2G7 M4S3R|MxKM7:TR?= M37IdlMxKG2rbh?= MmPhSG1UVw>? NVPrT|lNe2mpbnnmbYNidnSueTDpcoNz\WG|ZYOgeIhmKGGldHn2ZZRqd25ib3[gVGtC NXe1UIRuOjZyMkWxN|c>
PC-3 M3;LSmZ2dmO2aX;uJGF{e2G7 MluwOFAhyrWP M4X6dFIhcA>? M3n1cmROW09? M{n1W4xm[WS|IITvJHBROkFiYXP0bZZifGmxbh?= NHG4SHczPjB{M{izOi=>
PC-3 M1\nbWNmdGxiVnnhZoltcXS7IFHzd4F6 NE\mdIs1OCEEtV2= MlG4NlQwPDhxN{KgbC=> M2LzOmROW09? MUfk[YNz\WG|ZYOgZ4VtdCC4aXHibYxqfHlidHnt[UBl\XCnbnTlcpRtgQ>? MoG5NlYxOjN6M{[=
SCG NVjH[otZTnWwY4Tpc44hSXO|YYm= MmnWNlAh|ryPwrC= MWrEUXNQ NX7GR3dJemW4ZYLzbYJtgSC|dYDwdoV{e2W|IFnLWkB4cXSqIHGgTWM2OCCxZjCyOE41KM7:TR?= M4SyVFI2QTZ{MUOy
HEK-293 M4j0PWZ2dmO2aX;uJGF{e2G7 NVL6Rm81OzVizszNxsA> NXjT[nY1TE2VTx?= NYi2W452cW6mdXPld{BiKGOxboPwbYN2d3W|IPMAoIlv[WO2aY\heIlwduLCnTDv[kB1cGViS4[yMlEh[3W{cnXueC=> NIrEdmkzPTl4MkGzNi=>
SCG M1HHRmZ2dmO2aX;uJGF{e2G7 MnHBNVAxKM7:TdMg NYX2d5VlTE2VTx?= NFrCUVNz\WS3Y3XzJJRp\SCneHPpeIFjcWyrdImgc4YhW0OJIH7leZJwdnN? MnnxNlU6PjJzM{K=
PCCL3 MUDGeY5kfGmxbjDBd5NigQ>? NILvO5UyOCEEtV2= M{nLO|I1KGh? MofJ[Y5p[W6lZYOgSJVQgDJicILvcY91\XJidILhcpNkemmydHnvckBi[3Srdnn0feKh6oDN Mn3INlU6PjB7NU[=
3T3-L1 preadipocytes Mnv6SpVv[3Srb36gRZN{[Xl? M4m5cVExKM7:TdMg MVSxNkBp MWnpcoR2[2W|IFPSSWIheGixc4Doc5J6dGG2aX;uJIFv\CCFL1XCVO6zKGW6cILld5Nqd25? MXqyOVkzQDB3OB?=
H295R  MVzGeY5kfGmxbjDBd5NigQ>? NWnVW2JoOTEEoN88US=> M2fSdlQ5yqCq M4rxU4lv[3KnYYPld{B{fGW{b3nkJI1mfGGkb3zpeIV{KGmwIITo[UBidmS{b3flckwhdWmwZYLhcI8uKGGwZDDncJVkd2OxcoTpZ49q\CCyYYToe4F6ew>? MWSyOVg3QTV3Nh?=
PBMC NFrmWFRHfW6ldHnvckBCe3OjeR?= MlK3OVDDqM7:TR?= NUW0XFBTOjUEoHlCpC=> MnHRbY5pcWKrdIOgeIhmKGmwY4LlZZNm\CC|ZXPy[ZRqd25ib3[gWG5HKGmwZIXj[YQh[nlidHjlJGRRTQ>? NW\mRllFOjV6Nk[wO|k>
GLUTag  NF7XXnpHfW6ldHnvckBCe3OjeR?= NFPxV20yOOLCidM1US=> MUiwM|IwPCCq NGW3T|J{fGmvdXzheIV{KEeOUD2xJJNm[3KndHnvckBkd3S{ZXH0[YQhf2m2aDDJRm1Z M2jFW|I2QDN{NkOx
GLUTag  MlvtSpVv[3Srb36gRZN{[Xl? NUD4O5k6OTEkgJpCuW0> Mmj2OEBp NV;sdIxYcW6lcnXhd4V{KHSqZTDwR3JGSiCuZY\lcJMhf2m2aDD0bIUhUUKPWB?= NFy4elkzPTh|Mk[zNS=>
BAECs MV;GeY5kfGmxbjDBd5NigQ>? NVnsSYo6OjVizszN M2LQdlI1KGh? M3;EeYVvcGGwY3XzJJRp\SCjY4TpeoF1cW:wIH;mJHBRSVMQsTDifUA2KM7:TTDy[ZN3\XKjdILvcEwhXDSKUzygc5IhPC2SQWC= NFKxcmszPTd7OEiyOi=>
PC12 MWfGeY5kfGmxbjDBd5NigQ>? Mmm1NlXDqM7:TR?= MUS0PEBp M1G1boFkfGm4YYTld{BkSU2S MX:yOVc3QTNyNR?=
GH3 M{nxN2Z2dmO2aX;uJGF{e2G7 NInLdlEyyqEQvF2= M3PFUlYucA>? NILtSYNifHSnboXheIV{KHSqZTDjc5Jz\WyjdHnvckBj\XS5ZXXuJHBTVCCjbnSgRo1idDFiZYjwdoV{e2mxbh?= NHi5UYQzPTd{N{CxPC=>
GH3 NGexSZlHfW6ldHnvckBCe3OjeR?= MVexxsDPxE1? MonmOk1p M1HoVYlv\HWlZYOgVHJNKGGwZDDCcYFtOSxiYoX0JI5wfCCFbH;jb{whdVKQQTDlfJBz\XO|aX;u MkHHNlU4OjdyMUi=
BeWo MYHGeY5kfGmxbjDBd5NigQ>? NX\RWIhHOTEkgJtOwG3DqA>? NH;sPIU4OiCq NHnwXnJFVVOR NX\afYdmdWWmaXH0[ZMhSmWZbzDj[YxtKGSrZn\ldoVvfGmjdHnvci=> MlLKNlU4OTN2MkW=
oocytes M4nZXmZ2dmO2aX;uJGF{e2G7 M1;nd|Uh|ryP NYDRSHVROjRiaB?= M4XRNIF1fGWwdXH0[ZMhemhvaX7zeYxqdiCjY4Tpc44hd25ib3;jfZRmKEeYQlSgd4lodmmoaXPhcpRtgcLi MlvFNlU4ODd6NUS=
SC MY\GeY5kfGmxbjDBd5NigQ>? MojMNE42KM7:TR?= MYmyOEBp MmTFcYlucWOtczD0bIUh\W[oZXP0JI9nKGODTWCgZY5idG:pczDvckBQOSCjbnSgUWJRKGW6cILld5Nqd25? M2XxcVI2PzB3OEe0
SC MVfGeY5kfGmxbjDBd5NigQ>? NUPndpFMOC53IN88US=> MYq3NkBp M2D5colv[3KnYYPld{Bjd3SqIFvyc5guOjBiYX7kJG8yKGW6cILld5Nqd25iaX6gZZhwdi2{ZXzheIVlKFOFczDieZQhd26ueTDLdo95NTJywrC= MoKxNlU4ODV6N{S=
UACC-647  NX:0bFZmTnWwY4Tpc44hSXO|YYm= NF3ncWhFVVOR MVLs[YFleyC2bzDhJJJqe2ViaX6gZ2FOWCCuZY\lcJMhMEWFNUFCpF3DqDJyLkO5xsDPxE1r Mn7NNlU4ODNyMkW=
UACC-647  Mn7uSpVv[3Srb36gRZN{[Xl? MWixNOKh|ryP NUTJTIxuOTVibXnu NYHwTlZKTE2VTx?= MlW2bY5pcWKrdIOgSXJMKHCqb4PwbI9zgWyjdHnvci=> NED3[HAzPTdyM{CyOS=>
UACC-647  MV\GeY5kfGmxbjDBd5NigQ>? MkDFNVDDqM7:TR?= NHvIeFcyPSCvaX6= M{Did2ROW09? MYDpcoNz\WG|ZYOg[WVHOiCyaH;zdIhwenmuYYTpc44hdGW4ZXzzxsA> NFnObXIzPTdyM{CyOS=>
SH-SY5Y  M{XYfGZ2dmO2aX;uJGF{e2G7 Mk\ZNVDDqM7:TR?= NWPt[W5MOcLiaNMg NXjO[FE3cW6lcnXhd4V{KEyXQzDhZ5Rqfmm2eR?= M4HsblI2PTl5NEOz
SH-SY5Y  MWHGeY5kfGmxbjDBd5NigQ>? MUGxNOKh|ryP NYXIbXNxOcLiaNMg MnezbY5kemWjc3XzJGFISzFibWLORUBt\X[nbB?= MXeyOVU6PzR|Mx?=
hADSCs MnX5SpVv[3Srb36gRZN{[Xl? MmXSOgKBkcL3TR?= NGniSY8{OCCvaX6= MYLpcoNz\WG|ZYOgZ2FOWCCuZY\lcJM> NFjOXmEzPTV7MUmwPC=>
HEK293  NILhPVVHfW6ldHnvckBCe3OjeR?= MV[15qCKyrWP MWizNEBucW5? M17NTolv[3KnYYPld{BkSU2SIHzleoVtew>? MnrqNlU2QTF7MEi=
3T3-L1 M3H2ZWZ2dmO2aX;uJGF{e2G7 MWWyMlUwPSEQvF2= M{HTPFI1KGkEoB?= MYjzbYdvcW[rY3HueIx6KGSnY4LlZZNmeyCDVFfMJJBzd3SnaX6g[ZhxemW|c3nvckBifCCjbHyg[I9{\XNidHXzeIVl NGPPR5EzPTV7MEW5Oy=>
OCI-Ly1  NGS4OZBHfW6ldHnvckBCe3OjeR?= NEewWZc1OMLizszN NGXNXGkyyqCqwrC= M1uwUGROW09? NUDhb3cycW6mdXPld{B1cGViaX7jdoVu\W62IH;mJINCVVBiY3;uZ4VvfHKjdHnvcpM> NXLlV2E{OjV3N{[yNlA>
OCI-Ly18  NF3wPFhHfW6ldHnvckBCe3OjeR?= NVPpN4FsPDEEoN88US=> NWDDe5pLOcLiaNMg Mm\CSG1UVw>? MoDxbY5lfWOnczD0bIUhcW6lcnXt[Y51KG:oIHPBUXAh[2:wY3XueJJifGmxboO= MUGyOVU4PjJ{MB?=
BeWo NHyzbWdHfW6ldHnvckBCe3OjeR?= Ml7INlDDqML3TR?= M1ftUFQ5yqCq NH7QS2hFVVOR M4Hleolv[3KnYYPld{B1cGViZHnm[oVz\W62aXH0bY9vKG:oIFLlW48h[2WubIO= M4jGZ|I2PTZ4N{Sw
BeWo NWjYdYc{TnWwY4Tpc44hSXO|YYm= MkDQNlDDqML3TR?= M2XXRlQ5yqCq MUTEUXNQ M2K3T4lv[3KnYYPld{B1cGViYXTo[ZNqd25ib3[gWGhRNTFibX;uc4N6fGW| NX;OZZY2OjV3Nk[3OFA>
LNCaP  M{DvSmZ2dmO2aX;uJGF{e2G7 Mlz6NVDDqM7:TR?= MmTyNVIhcMLi NV;OXo9{TE2VTx?= M2rNVIlv\HWlZYOgZUBlemGvYYTpZ{BqdmO{ZXHz[UBw\iCFUlXCNUBi[3Srdnn0fS=> MUKyOVU1QDB7OR?=
ThGCs  MojOSpVv[3Srb36gRZN{[Xl? MWexNQKBks7:TR?= NVnT[4E4POLCini= NYDQNXB4[XWpbXXueJMhUEmIMVGgcIV3\Wy|IIToZZQhf2W{ZTDzeIlufWyjdHXkJIJ6KEOxQ3yy MYiyOVQ{OzB{Nx?=
ThGCs  MWjGeY5kfGmxbjDBd5NigQ>? MU[xNQKBks7:TR?= M3TS[VTjiIqq NV7NUVQ6cW6lcnXhd4V{KEOxQ3yyMYlv\HWlZXSgSWRPOsLiZ3Xu[UBmgHC{ZYPzbY9v Ml;kNlU1OzNyMke=
ThGCs  NXr5VIw{TnWwY4Tpc44hSXO|YYm= MUmxNQKBks7:TR?= M13WR|MhcA>? M37UOolvcGmkaYTzJJRp\SCnZn\lZ5Qhd2ZiSELPNkBwdiCHRF6yJI1TVkF? MUSyOVQ{OzB{Nx?=
RBMECs NHvpNIpHfW6ldHnvckBCe3OjeR?= MX:wMlA2NzBwNT:1JO69VQ>? NYCxTmlUOC5{NTDo MYfpcoNz\WG|ZYOgZ2FOWCClb37j[Y51emG2aX;u M2roXFI2PDF4NkWx
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RBMECs MUTGeY5kfGmxbjDBd5NigQ>? NYL3UVU1PcLizszN Ml3NNUBp MVPwdoV3\W62czD0bIUhTU2DUD3JTU1qdmS3Y3XkJHRGTVJidnHseYUh\GWlcnXhd4U> MVqyOVQyPjZ3MR?=
RBMECs NInsNFNHfW6ldHnvckBCe3OjeR?= NEK1Vmo2yqEQvF2= NEjyOGYyKGh? NWXae3BQeHKndnXueJMhfGinIHnuZ5Jm[XOnIHnuJGhTWCCobIX4JIFkem:|czD0bIUhSlSEIHnu[JVk\WRiYomgJGVOSVBvSVm= NVO3Sow3OjV2MU[2OVE>
RBMECs NE[wN3FHfW6ldHnvckBCe3OjeR?= MWG1xsDPxE1? NE\2cmUyKGh? NYTzNI5wcW6qaXLpeJMhfGinIHTlZ5Jm[XOnZDDv[kBidW:3boSgc4YhYk9vMTDpckBOTnNiaX7keYNm\CCkeTDFUWFRNUmL MkPtNlU1OTZ4NUG=
RBMECs MW\GeY5kfGmxbjDBd5NigQ>? MV:1xsDPxE1? M{\G[FEhcA>? NIn5bVJz\X[ncoPld{B1cGViY3jhcodmeyCrbjDaU{0yKGSrc4TybYJ2fGmxbjDz[YVvKHerdHigSW1CWC2LSTD0doVifG2nboS= Mn3GNlU1OTZ4NUG=
RBMECs MW\GeY5kfGmxbjDBd5NigQ>? MmSzOeKh|ryP NYXob|BDOSCq NUXscWN6[myxY3vzJJRp\SCHTVHQMWlKNWmwZIXj[YQh[2ijbnflJIlvKE2OQzDwbI9{eGixconsZZRqd25? Mli2NlU1OTZ4NUG=
RBMECs M3LHPGZ2dmO2aX;uJGF{e2G7 NGjCS2Q2yqEQvF2= NXrJRVdZOSCq NFzYdYtjdG:la4OgeIhmKGGldHnuJIN6fG:|a3Xs[ZRwdiC{ZXHydoFv\2WvZX70JJNm\W5id3n0bEBGVUGSLVnJJJRz\WG2bXXueOKh MUGyOVQyPjZ3MR?=
Primary bovine chondrocytes Mk\GS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MlHwOe69VQ>? NFXTUYY1QCCq NX\CXFdnemW4ZYLz[ZMhfGinIHnubIljcXSxcomg[YZn\WO2IH;mJINmdGWlb4jpZkBwdiCycn;sbYZmemG2aX;uJIlvKGe{b4f0bEBxdGG2ZTDjbI9v\HKxY4n0[ZM> NWPaXolzOjV2ME[wNVY>
EM1  MnnPSpVv[3Srb36gRZN{[Xl? NE[3RYoyPeLCit88US=> MUG0PEBp M3PabJJm\HWlZYOgeIhmKGW6cILld5Nqd25ib3dCpGxKTsLib4NCpHBVT1N{wrDpcuKhS0GOUj2gc5LDqEWSQVOyMZNqdGWwY3XkJGVOOSClZXzsd:Kh MkWwNlU{Pzh4NkG=
BeWo  NXTpVZdoTnWwY4Tpc44hSXO|YYm= M130blIxyqEEtV2= NIXIOmY1QMLiaNMg MUfEUXNQyqB? MkHNbY5kemWjc3XzJJRp\SCkZYThMYhETyC{ZXzlZZNm NEW2fYkzPTN4MkK2NC=>
BeWo  NF;2NodHfW6ldHnvckBCe3OjeR?= MWGyNOKhyrWP MnXyOFjDqGkEoB?= MVzEUXNQyqB? MX3kc5dvemWpdXzheIV{KHSqZTDs[ZZmdCCxZjDUUWVOTjF4 MlHFNlU{PjJ{NkC=
BeWo  MkDtSpVv[3Srb36gRZN{[Xl? NXT1dY1SOjEEoNM1US=> NVXLc2ZDPDkEoHlCpC=> M3n6XWROW00EoB?= MV\kc5dvemWpdXzheIV{KHSqZTDs[ZZmdCCxZjDHR20uOQ>? MoO1NlU{PjJ{NkC=
granulosa cells MlvPSpVv[3Srb36gRZN{[Xl? M4nPd|ExKM7:TR?= MV6xNk8zPCCq M1K4Rolv[3KnYYPld{B1cGVibHX2[Yx{KG:owrDSS3MzyqCvUl7B NYTL[IIyOjV|M{mxNFU>
granulosa cells NUjwS4tPTnWwY4Tpc44hSXO|YYm= M{nCUFExKM7:TR?= MlLVNVIwOjRiaB?= M{K5folv[3KnYYPld{B1cGVibHX2[Yx{KG:oIILldI9zfGW{IHHjeIl3cXS7IH\vdkB1cGVibH;u[4V{fCCocnHncYVvfCBq4pkSPFU1NytzOGLHV|IvVFWFKR?= Mn7aNlU{OzlzMEW=
granulosa cells M2LLPGZ2dmO2aX;uJGF{e2G7 MnXVNVAh|ryP MljqNlQhcA>? MYTpcoNz\WG|ZYOgeIhmKGmwdHXud4l1gSCxZjDEUmEweHKxdHXpckBkd22ybHX4 MoT3NlU{OzlzMEW=
granulosa cells Ml[wSpVv[3Srb36gRZN{[Xl? NUThb|I1OTBizszN M3nR[|I1KGh? MWTpcoNz\WG|ZYOgeIhmKGyndnXsd{Bw\iCUR2OyJJBzd22xdHXyJIFkfGm4aYT5 MYmyOVM{QTFyNR?=
SK-N-AS  NXPnOmQzS2WubDDWbYFjcWyrdImgRZN{[Xl? NYTNUI1lOTBizszNxsA> MY[yOE81QCCq MXTlcohidmOnczD0bY1mNWSncHXu[IVvfGy7IHPlcIx2dGG{II\pZYJqdGm2edMg MlXDNlUzPjZyNkO=
SK-N-AS  M1zuXGZ2dmO2aX;uJGF{e2G7 NXXwV4tsOTBizszNxsA> M1LkVVI1KGh? NFTlSY9qdmO{ZXHz[ZMhfGinIHPBUXAhdGW4ZXzzxsA> MVWyOVI3PjB4Mx?=
SK-N-AS  NHPFSVNHfW6ldHnvckBCe3OjeR?= MkjMNVAh|ryPwrC= MkS4NlQhcA>? NWTqT4FxcW6lcnXhd4V{KHSqZTDlfJBz\XO|aX;uJI9nKGO7Y3zpckBFOQ>? M1i5R|I2OjZ4ME[z
SK-N-AS  NHLtZoVHfW6ldHnvckBCe3OjeR?= M1m0[VExKM7:TdMg NFfzVno{OCCvaX6= MXHpcoR2[2W|IIDoc5NxcG:{eXzheIlwdiCxZjFOtk1k[XSnbnnuJEh{\XJ4N{WpMEBxNUeVS{ROtkApe2W{OTmgZY5lKGOxbnPvcYl1[W62IHjp[4hmeiCuZY\lcJMhd2ZiYXP0bZZmNCC3boDoc5NxcG:{eXzheIVlNCEQsj3jZZRmdmmw MlT1NlUzPjZyNkO=
SK-N-AS  NF6ze|JHfW6ldHnvckBCe3OjeR?= Ml;PNVAh|ryPwrC= M4j3S|ExNzNyL{[wJI1qdg>? NXPZWHBTcW6lcnXhd4V{KGyndnXsd{Bw\iCyLd8yMYNifGWwaX6gLJNmejZ5NTmgZY5lKGmwZIXj[ZMh[WOldX31cIF1cW:wIH;mJJAu|rJvY3H0[Y5qdiBqc3XyOlc2MSCrbjCodIVzcSmwdXPs[YFzKHKnZ3nvcpM> NUPpNnAyOjV{Nk[wOlM>
SK-N-SH NWW0TZRzS2WubDDWbYFjcWyrdImgRZN{[Xl? M{PoblExKM7:TdMg MXO0PEBp MoHo[Y5p[W6lZYOgV2suVi2VSDDu[ZVzd2KuYYP0c41iKGOnbHygeoli[mmuaYT5 MViyOVI3PjB4Mx?=
HEK‐CFTR NWn6dGFETnWwY4Tpc44hSXO|YYm= MnTmNwKBmzVywrFOwG0> MofBNE0yOiCvaX6= M2nrfmROW00EoB?= NX6xSnFTcW6mdXPld{BiKGSxc3ZihLBl\XCnbnTlcpQhcW:maXTlJIVn\my3eNMg NELMOmMzPTJ4M{KwOy=>
L6 NULCeVl2TnWwY4Tpc44hSXO|YYm= NGjPO5E1OCEEtV2= NYrwZ|lCOjRiaB?= MULpcohq[mm2czDEUWgyNWmwZIXj[YQhSWu2IHHjeIl3[XSrb36= M2LK[FI2OjR5NUWw
MIN6  M{PkcWZ2dmO2aX;uJGF{e2G7 M3y1blExKM7:TdMg NESwcoI{KGh? MYfpcoNz\WG|ZYOgSFMhdVKQQTDlfJBz\XO|aX;u MYGyOVI1OTF{NB?=
ventricular cardiomyocytes  NGjsWWtHfW6ldHnvckBCe3OjeR?= NH;X[YQxNjBzLUGwJO69VQ>? M3;ZPYlv[3KnYYPld{Ah[0GPUDDhZ4N2dXWuYYTpc44> M1i4VlI2OjB|MUGz
ventricular cardiomyocytes  MUTGeY5kfGmxbjDBd5NigQ>? M1v4SFAvODFvMUCg{txO MnPI[ZZwc2W|IHHuJIlvd3S{b4DpZ{Bz\XOyb37z[UAyOjEEsUG1KUBi[m:4ZTDiZZNidCC5aYToJIFvKEWFNUFCpI9nKDJwMjFCuW0> NY\DcYFxOjV{MEOxNVM>
BeWo  MWHGeY5kfGmxbjDBd5NigQ>? M4C3elIxKML3TR?= M1T1O|Q5KGh? MlLJSG1UV8Li NUfRbYtTcW6mdXPld{Bk\WyuIH\1d4lwdg>? M32wTFI2OTh2NEe3
THP-1  M1\ueGZ2dmO2aX;uJGF{e2G7 NGTENlgyNzFyIN88US=> NXjUW29FOsLiaB?= M{D5dGROW00EoB?= NV\IT5Rke3WycILld5NmeyCPQ2CtNUBxem:mdXP0bY9vyqB? NUWwUoVIOjVzNUS4PFI>
Huh-7 M4TMcGZ2dmO2aX;uJGF{e2G7 MWCwMVIxKM7:TR?= NFeyOXEzKGkEoB?= MUDy[ZN2dHS|IHnuJIEh\G:|ZT3k[ZBmdmSnboSgbY5kemWjc3WgbY4h[y2PeXOg[ZhxemW|c3nvckBifCC2aHWgdJJwfGWrbjDhcoQhdVKQQTDs[ZZmdHN? NXfmdoN6OjVzMEm4N|Q>
C6 NWmxR3pNTnWwY4Tpc44hSXO|YYm= NEf0dnIyOCEQvF5CpC=> NITFbWkzOCCvaX6= MXPpcoNz\WG|ZYOgZ2FOWCCjY3P1cZVt[XSrb36= NVPQU5dMOjVyNkm0NVc>
SW480 NYDwPHhMTnWwY4Tpc44hSXO|YYm= MkXtOFDDqM7:TR?= NHHmVIQ1QMLiaB?= M1q1VGROW09? MYLhZ5RqfmG2ZYOgVHAzSQ>? M4TOPFI1QTl5NEWx
HT-29  M2LXVGZ2dmO2aX;uJGF{e2G7 NH7hWpQ1OMLizszN M3GzZlQ5yqCq MljqSG1UVw>? MofZZYN1cX[jdHXzJHBROkF? M{PIOFI1QTl5NEWx
SW480 MnTVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MUG0NOKh|ryP MVWwMVczKGh? M2i1dWROW09? MWjpcohq[mm2czDj[YxtKGe{b4f0bEB1cW2nIHTldIVv\GWwdHz5 NYrCWpk{OjR7OUe0OVE>
HT-29  NIXwOYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NGLXbJk1OMLizszN MnfYNE04OiCq NVO5W3doTE2VTx?= Mnv1bY5pcWKrdIOgZ4VtdCCpcn;3eIghfGmvZTDk[ZBmdmSnboTsfS=> NHjzbpgzPDl7N{S1NS=>
SW480 NELNWWlHfW6ldHnvckBCe3OjeR?= NW\4RZBHPDEEoN88US=> NGThWos4KGR? M{DaZ2ROW09? MUjy[YR2[2W|IHPvcI9vd3OyaHXy[UBnd3KvYYTpc44h[2GyYXLpcIl1gcLi NX;acVN2OjR7OUe0OVE>
HT-29  MlnRSpVv[3Srb36gRZN{[Xl? MXu0NOKh|ryP MXq3JIQ> MV;EUXNQ NWX1VYdremWmdXPld{Bkd2yxbn;zdIhmemViZn;ycYF1cW:wIHPhdIFjcWyrdIpCpC=> M3PJUlI1QTl5NEWx
SW480 NWjLZ3ZZSXCxcITvd4l{KEG|c3H5 Mn3xOFDDqM7:TR?= NE\UR241QMLiaB?= M1q2V2ROW09? NXTBW4lYcW6mdXPld{BidiCjY4TpeoF1cW:wIH;mJINie3Cjc3WgN{84 M2LKSlI1QTl5NEWx
HT-29  Mn;uRZBweHSxc3nzJGF{e2G7 M2jWOlQxyqEQvF2= MVm0POKhcA>? MWnEUXNQ M4TPdIlv\HWlZYOgZY4h[WO2aY\heIlwdiCxZjDjZZNx[XOnIEOvOy=> NXrpPZNiOjR7OUe0OVE>
SW480 MV\BdI9xfG:|aYOgRZN{[Xl? MVO0NOKh|ryP Mlu0OFjDqGh? NV\COYRJTE2VTx?= NYLNOHRXcW6mdXPld{BkcGGwZ3XzJIlvKHSqZTDwbI9{eGixconsZZRqd25ic4TheJV{KG:oIGDQNmEhfGG{Z3X0dy=> NVHFOW94OjR7OUe0OVE>
HT-29  MknjRZBweHSxc3nzJGF{e2G7 MkDrOFDDqM7:TR?= MlL1OFjDqGh? MofrSG1UVw>? Ml\zbY5lfWOnczDjbIFv\2W|IHnuJJRp\SCyaH;zdIhwenmuYYTpc44he3SjdIXzJI9nKFCSMlGgeIFz\2W2cx?= NXzRXFF[OjR7OUe0OVE>

... Click to View More Cell Line Experimental Data

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

溶解度 (25°C)

体外 DMSO 82 mg/mL (199.75 mM)
Ethanol 37 mg/mL (90.13 mM)
Water Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 410.5
化学式

C22H34O7

CAS号 66575-29-9
稳定性 powder
in solvent
别名 Coleonol

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (g) = 浓度 (mol/L) x 体积 (L) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、MSDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01254006 Completed Glaucoma University of Roma La Sapienza|vingolo enzo maria|domanico daniela|salvatore serena null --

技术支持

在订购、运输、储存和使用我们的产品的任何阶段,您遇到的任何问题,均可以通过拨打我们的热线电话400-668-6834,或者技术支持邮箱tech@selleck.cn,直接联系到我们。我们会在24小时内尽快联系您。

操作手册

如果有其他问题,请给我们留言。

  • * 必填项

cAMP Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID