• PDE1
  • PDE2
  • PDE3
  • PDE4
  • PDE5
  • PDE6
  • PDE10A
  • PDE9
  • PDE4B

PDE4B 抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S2620 GSK256066 GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2. Pan PDE4B, IC50: 3.2 pM
S1430 Rolipram (ZK-62711) The PDE4 selective inhibitor, Rolipram (ZK-62711, SB 95952), inhibited immunopurified PDE4B and PDE4D activities similarly, with IC50 values of approx. 130 nM and 240 nM respectively; an anti-inflammatory agent. Pan PDE4B, IC50: 130 nM
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