• PRMT5
  • PRMT4
  • PRMT6
  • PRMT1
  • PRMT8
  • PRMT3

PRMT6 选择性抑制剂

目录号 产品名 产品描述 Selective / Pan IC50 / Ki
S7820 EPZ020411 2HCl EPZ020411 is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM. Selective PRMT6, IC50: 10 nM
S8112 MS023 MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. Pan PRMT6, IC50: 4 nM
s8147 MS049 MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. Pan PRMT6, IC50: 43 nM
S8858 GSK3368715 3HCl GSK3368715 3HCl is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. Pan
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