Integrin beta 1(CD29) Rabbit Recombinant mAb

目录号:A5721

Filter:

WB

规格	价格	库存	购买数量
20ul	447.55	现货
100ul	1500.64	现货
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使用信息

抗体应用

wb,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

150kDa

抗体类型

Rabbit

浓度

1mg/ml

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

Datasheet & SDS

生物描述

特异性

Integrin beta 1(CD29) Rabbit Recombinant mAb detects endogenous levels of total Integrin beta 1(CD29).

背景

Integrins comprise a group of transmembrane heterodimeric proteins consisting of α and β subunits that drive most of the interactions between cells and the extracellular matrix (ECM). Integrin beta 1 (ITGB1) is aberrantly expressed in human breast carcinoma and contributes to diverse malignant phenotypes, including epithelial-to-mesenchymal transition (EMT). The multiple downstream signaling pathways of β1, including FAK, PI3K and ERK/MAPK, coordinating signaling through receptor tyrosine kinases (RTKs), are involved in the modulation of tumor initiation, progression, and ultimately metastasis.

实验方法

参考文献	https://pubmed.ncbi.nlm.nih.gov/26728650/

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