天然产物库 <b>2661</b>种天然产物的独特集合，可用于高通量筛选和高内涵筛选。

天然产物

目录号	产品名	产品描述
E3000	Ligusticum Sinense Extract	Ligusticum Sinense Extract is extracted from <i>Ligusticum sinense</i>, a Chinese medicinal plant.
E3603	Ramulus Mori Extract	Ramulus Mori Extract is extracted from Ramulus mori (Mulberry twigs), the dry branch of <i>Morus alba</i> L.. Ramulus Mori is a traditional medicine widely used for diabetes treatment. The major active components of Ramulus Mori are mulberroside A, oxyresveratrol, resveratrol, 4-hydroxycinnamic acid, 7-hydroxycoumarin, and morin, and the components have been demonstrated to possess anti-cancer, anti-hypertensive, anti-diabetic, and anti-inflammatory properties.
E3604	Adenophora stricta Extract	Adenophora stricta Extract is extracted from <i>Adenophora stricta</i> Miq.. Adenophora stricta is commonly used to reduce phlegm, clear lung and tonify stomach.
E3605	Sea buckthorn Extract (fruits)	Sea buckthorn Extract (fruits) is extracted from the fruits of sea buckthorn (<i>Hippophae rhamnoides</i> L.). Sea buckthorn has significant cardioprotective activity and exerts many positive healing effects on the cardiovascular system, including inhibiting blood platelet activation (especially platelet aggregation), lowering cholesterol concentration and blood pressure, and providing antioxidant activity. Sea buckthorn also has antibacterial and antiviral properties.
E3606	Sea buckthorn Extract (leaves)
E3607	Crateva nurvala Extract
E3608	Semen astragali complanati Extract
E3609	Elaeagnus angustifolia Extract
E3610	Amomum villosum Extract
E3611	Camellia japonica Extract
E3612	Cremastra appendiculata Extract
E3613	Sophora tonkinensis Extract
E3614	Arnica montana Extract
E3615	Anisodus tangutcus Extract
E3616	Kaempferia galanga Extract
E3617	Galega officinalis Extract
E3618	Yam Extract
E3619	Lonicerae Flos Extract
E3620	Corni Fructus Extract
E3621	Crataegi fructus Extract
E3623	Pelargonium hortorum Extract
E3624	Phytolaccae Radix Extract
E3625	Cnidii Fructus Extract
E3626	Snake Gallbladder Extract
E3627	Belamcandae Rhizoma Extract
E3629	Lycopodii Herba Extract
E3630	Massa Medicata Fermentata Extract
E3631	Cimicifugae Rhizoma Extract
E3632	Rehmanniae Radix Extract
E3633	Ginger Extract
E3634	Ginger Extract(1%)
E3635	Chasteberry Extract
E3636	Ocimum sanctum Extract
E3637	Acorus tatarinowii Extract
E3638	Lysinotus pauciflorus Extract
E3639	Gypsum fibrosum Extract
E3640	Dendrobii caulis Extract
E3641	Salvia Chinensis Benth Extract
E3642	Haliotidis concha Extract
E3643	Pomegranate Peel Extract
E0840	Yakuchinone A	Yakuchinone-A是从姜科植物益智中分离得到的一种天然产物，对前列腺素（prostaglandins，PGs）和白三烯（leukotrienes，LTs）的合成有很强的抑制作用。
E2012	Ginkgolide K	Ginkgolide K通过AMPK/mTOR/ULK1信号通路诱导保护性自噬，具有神经保护作用。
S0970	Curzerene	Curzerene是从仙茅根茎中分离得到的具有抗癌活性的倍半萜类化合物，可抑制谷胱甘肽S-转移酶A1(GSTA1)的mRNA和蛋白表达，也可诱导细胞凋亡。
E0583	Isoscabertopin	Isoscabertopin is a sesquiterpene lactone isolated from <i>Elephantopus scaber L</i> and shows anti-tumor activities.
E0543	OJV-VI	OJV-VI is isolated from <i>ophiopogonis</i>.
S6370	Dendrophenol	Dendrophenol (Moscatilin) 是一种来自石斛的天然的双苄基化合物，具有潜在的抗诱变活性。
S0938	Sakuranetin	Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E0505	Olive oil	Olive oil来自欧洲橄榄油树Olea europae的果实，对人体健康有有益的影响，具有抗氧化活性和抗炎活性。
E0506	Soybean oil	大豆油是一种从大豆种子中提取的大豆植物油。
E0656	7-Methylcoumarin	7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
E0748	Opoponax oil	Opoponax oil是从Commiphora erythraea (opoponax)中分离提取的，具有很好的杀虫性能。
E1124	Narciclasine	Narciclasine (Lycoricidinol)是一种异羧基生物碱，在他莫昔芬耐药的乳腺癌细胞中通过不同的机制靶向STAT3。Narciclasine通过直接与STAT3 SH2结构域结合，抑制STAT3的磷酸化、激活、二聚和核易位，导致STAT3降解。Narciclasine是一种植物生长调节剂。Narciclasine调节Rho/Rho激酶/LIM激酶/cofilin信号通路，显著增加GTPase RhoA活性，并以RhoA依赖的方式诱导肌动蛋白应激纤维的形成。
E0650	γ-Terpinene	γ-Terpinene (γ-TPN)是一种单萜类物质，是一种口服活性抗氧化剂化合物，可直接清除自由基。
E0651	Garlic oil	Garlic oil通过诱导II期药物代谢酶阻断烟草致癌物4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone(NNK)诱导的肺肿瘤发生。
S4448	Imidacloprid-urea	Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid.
E0653	Trans-ferulic acid	Trans-ferulic acid是高糖条件下AMPK的强效激活剂。
E0478	Procyanidin C1	Procyanidin C1是葡萄籽提取物中的一种多酚类成分，通过其对衰老细胞的作用，增加了小鼠的健康寿命和寿命。PCC1是一种具有体内活性的天然感官治疗药物，它可能是一种延缓、缓解或预防年龄相关病理的潜在干预手段。
S0936	Aloin B	Aloin B (Isobarbaloin)是从芦荟中分离出来的，是Aloin的一种异构体，具有抗乙型肝炎病毒(HBV)的活性。
S0944	Benzoylaconitine	Benzoylaconitine (Isaconitine, Pikraconitin)是从中药附子中提取的一种生物碱，在IL-1β诱导的人滑膜细胞中，可通过MAPK、Akt、NF-κB信号抑制IL-6和IL-8的产生。
E0239	(-)-Catechin gallate	(-)-Catechin gallate ((-)-CG)是一种在绿茶提取物中发现的儿茶素多酚，具有多种生物活性。
E0240	Procyanidin B1	Procyanidin B1是一种具有抗氧化特性的天然多酚类化合物，可抑制Kv10.1通道(Kv10.1 channel)进而抑制肝癌的发展。
E0241	Asiaticoside B	Asiaticoside B is a triterpene glycoside isolated from Centella asiatica (L.) Urban, with anti-cancer activity.
E0242	Picrocrocin	Picrocrocin是产生藏红花苦味的化学物质，从藏红花中分离出来，可以抑制癌细胞的增殖。
E0243	Emodin-8-glucoside	Emodin-8-glucoside (Emodin glucoside B, Anthraglycoside B, Emodin glucoside B)是从芦荟中分离出来的蒽醌衍生物，与DNA的小凹槽结合。
E0244	Acevaltrate	Acevaltrate是一种来自草本植物缬草的活性成分，对GBM细胞凋亡的诱导具有显著的诱导作用。Acevaltrate抑制大鼠肾脏和脑半球Na+/K+-ATPase活性，IC50分别为22.8 μM和42.3 μM。
E0246	β-Anhydroicaritin	β-Anhydroicaritin是从Boswellia carterii Birdware中分离出来的，具有抗骨质疏松、雌激素调节和抗肿瘤特性。
E0247	Militarine	Militarine是白芨块茎的主要化学成分，具有显著的神经保护作用。
E0248	Rehmannioside D (Rhmannioside D)	Rehmannioside D (Rhmannioside D)是地黄中的一种环烯醚萜苷成分。
E0249	Pseudolaric Acid A	Pseudolaric acid A，一种Hsp90抑制剂，在HL-60、A549、SMMC-7721、HeLa和SW480细胞中的IC50分别为0.60μM、2.72μM、1.36μM、2.92μM和6.16μM，Pseudolaric acid A是土荆皮的主要生物活性成分，诱导细胞周期阻滞在G2/M期，通过caspase-8/caspase-3途径促进细胞死亡，具有有效的抗增殖和抗癌活性。
E0212	Cornuside	Cornuside 是一种从 Cornus officinalis SIEB. et ZUCC 果实中分离出来的双环烯醚萜苷化合物。Cornuside 通过抑制 RAW 264.7 巨噬细胞中的 NF-κB 活化来抑制脂多糖诱导的炎症介质。Cornuside 减弱大鼠皮质神经元的细胞凋亡。
E0213	Bruceine D	Bruceine D，从灌木 Brucea javanica (L.) Merr. (Simaroubaceae) 中分离出来，在各种人类癌症中具有抗肿瘤特性，包括胰腺癌、乳腺癌、肺癌、血液癌、骨骼癌和肝癌。Bruceine D 通过线粒体途径诱导人慢性粒细胞白血病 K562 细胞凋亡。
E0215	Isorhapontigenin	Isorhapontigenin (ISOR) ，从 Belamcanda chinensis 中分离出来，是二苯乙烯的衍生物。Isorhapontigenin 具有有效的抗氧化活性。Isorhapontigenin 抑制白细胞介素 1β 诱导的大鼠软骨细胞炎症和软骨基质损伤。
E0216	Hinokiflavone	Hinokiflavone，从 Selaginella P. Beauv、Juniperus phoenicea 和 Rhus succedanea 中分离得到，具有优异的药理活性，包括抗炎、抗氧化和抗肿瘤活性。Hinokiflavone 通过 EMT 信号通路诱导细胞凋亡并抑制乳腺癌细胞的迁移。
E0190	Invert sugar	Invert Sugar是一种流行的甜味剂。
E0211	Dihydroberberine	Dihydroberberine是小檗碱 (BBR) 的氢化衍生物，通过双重调节 NF-κB 和 MAPK 信号通路发挥抗炎作用。
S0941	3,29-O-dibenzoyloxykarounidiol	3,29-O-dibenzoyloxykarounidiol 是一种从 Trichosanthes kirilowii Maxim 中分离出来的三萜类化合物。
S5813	Isoginkgetin	Isoginkgetin是一种天然来源的双黄酮，具有抗肿瘤活性。Isoginkgetin 直接抑制 20S 蛋白酶体 (proteasome) 的糜蛋白酶样、胰蛋白酶样和半胱天冬酶样活性。Isoginkgetin 也是 Pre-mRNA 剪接(splicing) 的通用抑制剂。
S0958	Zingibroside R1	Zingibroside R1 从 Panax zingiberensis Wu et Feng（五加科）的根茎中分离得到，具有一定的抗 HIV-1 活性。Zingibroside R1 显示对 EAT 细胞摄取 2-脱氧-D-葡萄糖 (2-DG) 的抑制作用，IC50 为 91.3 µM，对 MT-4 细胞的生长具有抑制作用，CC50 为 46.2 µM。
E0206	Ginkgetin	Ginkgetin 是一种来自银杏叶的双黄酮，具有抗癌、抗炎、抗微生物、抗脂肪生成和神经保护作用。
E0207	Chebulinic acid	Chebulinic acid，一种从榄仁树果实中分离的酚类化合物，是一种新型流感病毒神经氨酸酶（Influenza viral neuraminidase）抑制剂。Chebulinic acid 也是一种抗血管生成剂，通过抑制 VEGF 起作用。Chebulinic acid 具有抗肿瘤活性。
E0208	Herbacetin	Herbacetin 是一种存在于亚麻籽中的天然类黄酮化合物，具有很强的抗氧化、抗肿瘤和抗炎活性。
E0209	Cinobufotalin	Cinobufotalin，可从巨蟾的皮肤分泌物中提取，是一种新型的 SREBP1 抑制剂，通过靶向脂肪生成来抑制肝细胞癌的增殖。
E0210	Quercetin 3-O-β-D-glucuronide	Quercetin 3-O-β-D-glucuronide (Miquelianin, Q3GA)是槲皮素代谢物之一，具有抗氧化活性。
E0222	Glaucocalyxin A	Glaucocalyxin A 是一种从 Rabdosia japonica var 中分离出来的具有生物活性的 ent-kauranoid 二萜。Glaucocalyxin A具有抗肿瘤和抗炎活性。Glaucocalyxin A 通过人膀胱癌细胞中的 PI3K/Akt 通路诱导 G2/M 细胞周期停滞和凋亡。
E0225	Licochalcone B	Licochalcone B (Lico B)，从 Glycyrrhiza uralensis Fisch 中提取出来，可诱导人肝癌细胞 HepG2 的细胞周期停滞和凋亡。Licochalcone B 通过破坏 NEK7-NLRP3 相互作用特异性抑制 NLRP3 炎性体。
E0226	Chebulagic acid	Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的，是一种可逆的、非竞争性的麦芽糖酶（maltase）抑制剂，Ki 值为 6.6 μM。Chebulagic acid 在 LPS 刺激的 RAW 264.7 细胞中显示出有效的抗炎作用。Chebulagic acid 还显示出有效的 COX-LOX双重抑制活性，对 COX-1、COX-2 和 5-LOX 的 IC50 值分别为 15 μM、0.92 μM 和 2.1 μM。
E0233	14-Deoxy-11,12-didehydroandrographolide	14-Deoxy-11,12-didehydroandrographolide (deAND)，一种在穿心莲 (Burm. f.) Nees 中的二萜类化合物，具有降血压、抗炎、抗哮喘和抗癌活性。
E0177	Hydrocortisone sodium succinate	Hydrocortisone sodium succinate (Hydrocortisone 21-hemisuccinate sodium salt) 对 IL-6 的生物活性有显着的抑制作用，IC50 为 6.7 μM。Hydrocortisone sodium succinate 可与糖皮质激素受体(glucocorticoid receptor) 结合，启动抗炎和免疫抑制介质的转录。
E0201	Hypaconitine	Hypaconitine (Deoxymesaconitine) 是一种从乌头属植物中提取的活性二萜生物碱。次乌头碱抑制 TGF-β1 诱导的上皮间质转化。
E0202	Benzoylmesaconine	Benzoylmesaconine (Mesaconine 14-benzoate) 是一种主要的乌头生物碱，从几种乌头属植物中分离出来，具有很强的药理活性，如镇痛和抗炎。
E0204	Poricoic acid A	Poricoic acid A 是从茯苓的表层中分离出来的 Poricic acid A 激活 AMPK 以减弱肾纤维化中的成纤维细胞活化和异常细胞外基质重塑。Poricic acid A 也是色氨酸羟化酶-1 (tryptophan hydroxylase-1, TPH-1) 的调节剂。
E0205	Strictosamide	Strictosamide 是 Nauclea officinalis Pierre ex Pitard（茜草科）的主要代表性成分，具有抗炎和镇痛活性。
S7758	Trabectedin	Trabectedin (Ecteinascidin 743, ET-743) 是一种从加勒比被囊动物 Ecteinascidia turbinata 中分离出来的具有抗肿瘤活性的海洋生物碱。Trabectedin 与小沟中鸟嘌呤的 N2 结合，导致 DNA 损伤并以启动子和基因特异性方式影响转录调控。
S0651	N-Butanoyl-L-homoserine lactone	N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) 是一种可切割的ADC接头，用于合成抗体药物偶联物（ADC）。N-Butyryl-L-homoserine lactone是一种小的可扩散信号分子，参与群体感应、控制基因表达和细胞代谢。
E0160	Hexaminolevulinate hydrochloride	Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride)是一种肿瘤光敏剂。
E0365	Fucoidan	Fucoidan是从海洋褐藻中提取的阴离子硫酸化多糖，具有广泛的生物活性，包括抗炎、抗癌、抗病毒、抗氧化、抗凝、抗血栓、抗血管生成和抗幽门螺杆菌等。
S0920	Ginkgolide J	Ginkgolide J 是银杏叶提取物萜烯三内酯混合物的次要成分，可抑制 GlyR 控制的通道，IC50 为 2.0 μM。Ginkgolide J 还抑制由 Aβ1-42 引起的啮齿动物海马神经元的细胞死亡。银杏内酯 J 具有抗炎活性。
E0198	Pristane	Pristane (2,6,10,14-Tetramethylpentadecane, TMPD) 是一种天然的饱和萜类烷烃，主要从鲨鱼肝油中提取，广泛用于诱导小鼠的肿瘤发生和大鼠的关节炎和狼疮性肾炎。
E1029	Miglustat	Miglustat (Zavesca, N‐butyldeoxynojirimycin, OGT 918) 是一种口服神经酰胺葡糖基转移酶（ceramide glucosyltransferase）抑制剂，可防止葡糖脑苷脂的溶酶体积聚。
E0196	Alloxan Monohydrate	Alloxan Monohydrate是最常用的致糖尿病药物，用于评估测试化合物的抗糖尿病或降血糖能力。
S9793	4-Hydroxynonenal	4-Hydroxynonenal (4-HNE, HNE, 4-hydroxy Nonenal, 4-hydroxy-2-nonenal) 是脂质过氧化的主要终产物之一，已被广泛接受为氧化应激的诱导剂。
E0150	Carrageenan	Carrageenan (kappa-Carrageenan) 是一种从食用红海藻中提取的天然碳水化合物（多糖）。Carrageenan具有抗凝活性、抗血栓形成活性、抗病毒活性、抗肿瘤活性和免疫调节活性。
E0149	Papain	Papain (papaya proteinase I) 是一种来自木瓜果实乳胶的巯基蛋白酶。Papain可分解软骨的细胞间基质。
E0156	Thioacetamide	Thioacetamide (TAA) 是一种常用于实验目的的肝毒素，单次给药后会导致小叶中心坏死。
E0154	Taurocholic acid sodium salt	Taurocholic acid sodium salt (Sodium Taurocholate, TANa)是牛磺胆酸的钠盐形式，存在于哺乳动物的胆汁中。Taurocholic acid用作利胆剂和利胆剂。
E0143	ITE	ITE (2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester)是一种有效的芳烃受体 (AhR) 内源性激动剂，可直接与 AHR 结合，Ki 为 3 nM。
S6812	Z-Guggulsterone	Z-Guggulsterone 是阿育吠陀药用植物 Commiphora mukul 的一种成分，在体外和体内抑制血管生成。Z-Guggulsterone 在小胶质细胞中具有抗炎作用。Z-Guggulsterone 通过内在的线粒体依赖性途径诱导胃癌细胞凋亡。
E0129	Oxysophocarpine	Oxysophocarpine (OSC) 是从 Sophora alopecuroides 中提取的生物碱。Oxysophocarpine 通过靶向 Nrf2/ HO-1 轴抑制口腔鳞状细胞癌 (OSCC) 的生长和转移。OSC 通过减弱 MAPK 来保护细胞免受细胞凋亡和炎症反应并削弱 miR-155 活性和 NF-κB 通路。
E0130	Apigenin-7-O-glucuronide	Apigenin-7-O-glucuronide (Apigenin-7-glucuronide) 是在奶蓟中发现的主要黄酮类化合物。Apigenin 7-o-glucuronide 抑制脂多糖激活的巨噬细胞中的肿瘤坏死因子 α (TNF-α) 和总亚硝酸盐释放。
E0015	Iberiotoxin	Iberiotoxin (IbTX) 是从蝎子 Buthus tamulus 中纯化的毒素。Iberiotoxin 是大电导 Ca(2+)-activated K+ channel的有效阻滞剂，Kd 约为 1 nM。
S0947	Cafestol	Cafestol是从咖啡豆中提取的天然二萜。Cafestol 诱导细胞凋亡并调节多种炎症介质以减轻炎症。Cafestol 抑制 PI3K/Akt 通路。Cafestol 还可以减少白血病细胞系 HL60 中 ROS 的产生。
E0023	5,7-Dihydroxychromone	5,7-Dihydroxychromone (DHC) 是一种从植物中提取的天然抗氧化剂，是 Nrf2/ARE 信号的有效激活剂。5,7-Dihydroxychromone也是 PPARγ 和 LXRα 的有效激活剂。5,7-二羟基色酮可能有助于调节血糖水平并显示抗糖尿病特性。
E0046	β-Cyclodextrin	β-Cyclodextrin (β-CD, Beta-Cyclodextrin) 是一种淀粉的环状衍生物，由部分水解淀粉（麦芽糖糊精）通过酶促过程制备。β-Cyclodextrin可用作络合剂以增加难溶性药物的水溶性并增加其生物利用度和稳定性。
E0124	Chelerythrine	Chelerythrine (Toddaline, Broussonpapyrine) 是一种有效的选择性 PKC 拮抗剂，IC50 为 0.66 μM。 Chelerythrine 还抑制 BclXL-Bak BH3 肽结合，IC50 为 1.5 μM。 Chelerythrine 具有抗肿瘤、抗糖尿病和抗炎活性。
S8152	Cucurbitacin I	Cucurbitacin-I (Elatericin B, JSI 124, NSC 521777)，一种从葫芦科植物中分离出来的天然细胞渗透性三萜，是一种新型的 JAK2/STAT3 选择性抑制剂。
S7580	Leptomycin B	Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) 是一种从链霉菌中分离的强效抗真菌抗生素，可作为核输出因子 CRM1 的特异性抑制剂。 Leptomycin B 通过共价抑制 CRM1 快速诱导癌细胞系的细胞毒性作用，IC50 值为 0.1 nM–10 nM。
E0037	Bradykinin	Bradykinin是一种有效的血管扩张肽，通过刺激特定的内皮 B2 受体发挥其血管扩张作用，从而导致前列环素、NO 和 EDHF 的释放。
S0950	Hibifolin	Hibifolin (Gossypetin-8-O-β-D-glucuronide) 是一种黄酮醇糖苷，是腺苷脱氨酶 (adenosine deaminase, ADA) 的潜在抑制剂，Ki 为 49.92 μM。 Hibifolin 在培养的皮层神经元中防止 β-淀粉样蛋白诱导的神经毒性。
E0010	Hypocrellin A	Hypocrellin A (HA) 是一种从 Shiraia bambusicola 中分离的苝醌，显示出抗病毒、抗菌和抗癌的活性。Hypocrellin A 还是 PKC 的选择性和有效抑制剂。
E0027	5-Hydroxymethylcytosine	5-Hydroxymethylcytosine (5hmC) 是哺乳动物基因组DNA中天然存在的成分，被认为是DNA的第六个碱基。5-Hydroxymethylcytosine是活性 DNA 去甲基化的中间代谢物。5-Hydroxymethylcytosine是已知会影响哺乳动物全局基因表达的表观遗传标记。
E0025	2-Hydroxybenzylamine	2-Hydroxybenzylamine (2-(Aminomethyl)phenol, 2-HOBA, NSC 127870) 是一种天然存在于荞麦中的化合物，是二羰基亲电试剂的选择性清除剂，可保护蛋白质和脂质不被这些亲电试剂修饰。2-HOBA 可减少炎症和斑块凋亡细胞，并促进胞吐作用和稳定斑块的特征。2-HOBA 具有用作营养补充剂的潜力，因为它能够防止氧化的破坏作用。
E0008	Atractylodin	Atractylodin (Atractydin) 是 Atractylodes lancea 根茎的主要成分之一，抑制 N-酰基乙醇胺水解酸酰胺酶 (NAAA) 的活性，IC50 为 2.81 µM。Atractylodin 还通过阻断 NPM-ALK 激活和 MAPK 来抑制白细胞介素 6 (IL-6)。
E0009	Harmane	Harmane (Harman, Aribine, Aribin, Locuturine, Locuturin, Loturine, Passiflorin, 1-Methylnorharman, NSC 54439)是多种食品、植物和饮料中的常见化合物。Harmane 是一种选择性 monoamine oxidase 抑制剂，对人 MAO A 和 MAO B 的 IC50 分别为 0.5 μM 和 5 μM。Harmane还可以抑制噬菌体 T4 诱导的紫外线核酸内切酶（UV endonuclease）的无嘌呤/无嘧啶核酸内切酶（apurinic/apyrimidinic (AP) endonuclease）活性。
E0022	Ophiopogonin D	Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) 是一种从中草药麦冬中分离得到的甾体糖苷，具有抗肿瘤作用。Ophiopogonin D 可通过调节 ITGB1/FAK/Src/AKT/β-catenin/MMP-9 信号轴抑制TGF-β1介导的MDA-MB-231细胞转移行为。Ophiopogonin D 还通过抑制小鼠肺上皮细胞中的 AMPK/NF-κB 通路来减轻 PM2.5 诱导的炎症。
S9197	Maltohexaose	Maltohexaose（Amylohexaose）是一种含有6个葡萄糖单位的多糖，可归类为麦芽糊精。
S0943	Arenobufagin	Arenobufagin是蟾蜍毒液中的天然蟾蜍二烯内酯，通过抑制 PI3K/Akt/mTOR 通路诱导人肝癌细胞凋亡和自噬。
S6909	Levomefolic acid	Levomefolic acid (5-MTHF, LMSR, Metafolin, Nutrifolin) 是一种天然的活性叶酸形式，在细胞水平上用于 DNA reproduction、半胱氨酸循环和同型半胱氨酸的调节等功能。
S6927	Dihydroresveratrol	Dihydroresveratrol 是一种具有显著生物活性的天然产物，一种有效的植物雌激素，是 hormone receptor 的调节剂。
S3166	Calcium 2-oxoglutarate	Calcium 2-oxoglutarate (Calcium oxoglurate, Calcium 2-oxopentanedioate, Calcium α-ketoglutarate, Calcium AKG, Calcium 2-ketoglutaric acid, Calcium oxoglutaric acid) 是2-oxoglutarate的钙盐形式。2-oxoglutarate 是自然存在于生物中的，是众所周知的在柠檬酸循环(Krebs cycle)中ATP或GTP产生的中间体。2-oxoglutarate 是 tyrosinase 的可逆抑制剂，其IC50值为15 mM。
S6100	Picrotoxin	Picrotoxin (Picrotin, Cocculin, Cocculus, NSC 403139) 是一种植物生物碱，是神经元 GABA 和 glycine receptors 的非竞争性拮抗剂。
S5910	Alpha-Estradiol	Alpha-Estradiol (α-Estradiol, 17 alpha-Estradiol, Alfatradiol, Epiestradiol, Epiestrol, Alora, 17 α-E2) 是一种天然的、非雌性化，是生理上几乎无活性的激素17β-雌二醇（17β- E2）的立体异构体，是雌激素 estrogen 的弱抑制剂。
S3761	Eucalyptol	Eucalyptol (NSC 6171, 1,8-Cineol, 1,8-cineole, 1,8-Epoxy-p-menthane, 1,8-Oxido-p-menthane, Cineol, Cineole) 是存在于许多植物，主要是桉树种，中的单萜类油，具有抗炎和抗氧化作用。Eucalyptol 通过抗炎细胞因子的抑制作用来控制气道的粘液分泌过多和哮喘。
S5417	Spectinomycin dihydrochloride pentahydrate	Spectinomycin dihydrochloride pentahydrate (Trobicin) 是一种广泛使用的抗生素，可通过阻止信使RNA的易位和核糖体上的转移RNA来抑制细菌蛋白质的合成。
S5972	Hydrocortisone hemisuccinate	Hydrocortisone hemisuccinate (A-hydrocort, Hydrocortisone 21-hemisuccinate) 是一种具有抗炎特性的生理性糖皮质激素，是 proinflammatory cytokine 的抑制剂，对 Interleukin-6 (IL-6) 和 IL-3 的IC50值分别为6.7 μM和21.4 μM。
S9827	Iodoacetamide	Iodoacetamide (IA, IAM, 2-Iodoacetamide) 是一种烷基化剂，通常在蛋白质组学样品制备过程中用于半胱氨酸的烷基化。
S5958	Metformin	Metformin (1,1-Dimethylbiguanide) 是一种广泛用于治疗2型糖尿病的药物，可激活肝细胞中的 AMP-activated protein kinase (AMPK)。Metformin 可促进单核细胞中的线粒体自噬。Metformin 可通过激活 JNK/p38 MAPK 途径和GADD153来诱导肺癌细胞凋亡。
S5937	DL-Carnitine	DL-Carnitine ((±)-Carnitin) 是L-Carnitine和D-Carnitine的外消旋混合物，可调节线粒体中的 fatty acid transport。DL-Carnitine 被发现对肌肉细胞和心肌无效或有毒。DL-Carnitine 可引起肌无力和心律不齐的症状。
S5955	Thiamine nitrate	Thiamine (Vitamin B1) nitrate 是一种必需的维生素，它在细胞从摄入食物中产生能量时发挥重要作用，并可增强正常的神经元活性。
S5888	Beclamide	Beclamide (N-Benzyl-3-chloropropionamide, beta-chlorpropionamide) 具有镇静和抗惊厥作用。
S5199	Oxytetracycline hydrochloride	Oxytetracycline (OTC, Oxycycin, Stevacin, Terramycin) hydrochloride 是一种抗生素，会干扰细菌产生必需蛋白质的能力。
S4486	Thiamine monochloride	Thiamine (Vitamin B1) monochloride 是一种必不可少的维生素 vitamin，它在摄取食物的细胞能量生产中起着重要作用，并能增强正常的神经元活性。
S4495	Quinine	Quinine 是一种来自cinchona tree的生物碱，是一种抗疟疾剂和钾通道 potassium channel 的抑制剂，可抑制电压诱发的mSlo3 (KCa 5.1)通道电流，脉冲至+100 mV，其IC50值为169 μM。
S4490	Tetracycline	Tetracycline (TC) 是一种广谱的抗生素，对多种微生物具有活性，包括革兰氏阳性和革兰氏阴性细菌、衣原体、支原体、立克次氏体和原生动物寄生虫。
S3590	Triolein	Triolein 是一种 metalloproteinase-1 (MMP-1) 的抑制剂，可降低辐射角化细胞中 IL-6 和 ROS 的表达。
S4713	Atropine	Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) 是一种具有竞争性的 muscarinic acetylcholine receptor (mAChR) 的拮抗剂，具有抗近视作用。
S5193	L-Thyroxine sodium salt pentahydrate	L-Thyroxine (Levothyroxine, L-T4) sodium salt pentahydrate 是一种合成的T4激素，可用于平衡甲状腺功能减退症。
S5260	ATP	ATP (Adenosine-Triphosphate, Adenosine 5'-triphosphate) 是一种多功能的三磷酸核苷，是免疫和炎症反应中重要的内源性信号分子。
S5790	Folinic acid	Folinic acid (Leucovorin) 是一种生物叶酸，可增加组织中叶酸还原的水平，从而促进对 thymidylate synthase (TS) 的抑制。
S6466	Eicosapentaenoic acid ethyl ester	Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) 是omega-3 fatty acid 药剂，可显著地降低 triglyceride (TG) 的水平并改善其他脂质参数而不会显着增加低密度脂蛋白(LDL)胆固醇的水平。
S4979	Procaine penicillin G	Penicillin G Procaine (PGP, Penicillin G Procaine, Bicillin C-R) 是一种将青霉素G与Procaine相结合的结晶复合物，一种β-内酰胺抗生素。
S5922	L-Carnitine hydrochloride	L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride 可改善氧饱和度，并抑制 leukotriene 的合成。L-Carnitine hydrochloride 的功能是将长链脂肪酰基辅酶A转运到线粒体中，以通过β氧化降解。
S0911	Hypaphorine	Hypaphorine 大量存在于王不留行vaccaria semen中，通过抑制 ERK 或/和NFκB信号通路来抵消炎症。
S4857	L-Ornithine	L-ornithine ((S)-2,5-Diaminopentanoic acid) 通过增加能量消耗的效率及促进氨的排泄而具有抗疲劳的作用。它是尿素循环中的关键反应物之一。
S3578	Pyrroloquinoline quinone	Pyrroloquinoline quinone (PQQ, Methoxatin) 是一种天然的抗氧化剂，具有抗氧化和抗衰老的作用。Pyrroloquinoline quinone 可预防雌激素缺乏引起的骨质疏松症。
S4496	Maltose monohydrate	Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose) monohydrate 是一种非必需营养素，可提供能量，是糖原和淀粉在肠内消化的中间产物，存在于发芽的谷物以及其他植物和蔬菜中。
S9631	Puromycin aminonucleoside	Puromycin aminonucleoside (NSC 3056, PAN, Stylomycin aminonucleoside, ARDMA, SAN) 是抗生素puromycin的氨基核苷部分，是 dipeptidyl-peptidase II 和 cytosol alanyl aminopeptidase 的可逆抑制剂，会在系膜细胞(MCs)中诱导凋亡，并伴有细胞活力下降和炎症反应增强。
S7428	Rocaglamide	Rocaglamide (Roc-A) 是从Aglaia物种中分离出来的一种有效的 heat shock factor 1 (HSF1) 活化的抑制剂，对HSF1的IC50值约为50 nM。Rocaglamide 可抑制翻译起始因子 eIF4A 的功能。Rocaglamide 还抑制 NF-κB 的活性。Rocaglamide 具有抗肿瘤活性。
S3569	Spermidine	Spermidine 是一种天然的多胺，可刺激细胞保护性 macroautophagy/autophagy。
S4438	Benzophenone	Benzophenone (Diphenyl ketone, Benzoylbenzene) 可滤除UVA和UVB射线，广泛用于各种防晒霜和个人护理产品中。
S4440	2-Phenylacetamide	2-Phenylacetamide 是从具有雌激素活性的 Lepidium apetalum Willd (LA) 的种子中分离出的主要化合物，可在子宫和MCF-7细胞中增加 Estrogen receptorα (ERα)、ERβ 和 GPR30 的表达。
S4425	Rifamycin S	Rifamycin S 是一种quinone和抗 Gram-positive bacteria(包括MRSA) 的抗生素，是一种用于治疗肺结核和麻风病的临床药物。Rifamycin S 可产生 reactive oxygen species (ROS)，并抑制微粒体脂质过氧化 microsomal lipid peroxidation。
S4436	Pleuromutilin	Pleuromutilin (Drosophilin B, Mutilin 14-glycolate) 是新型抗生素的先导化合物，它通过结合细菌的50S核糖体亚基来抑制细菌蛋白质的合成。
S4494	Methionine	Methionine (MRX-1024, D-Methionine) 是 GABAA receptor 的激活剂，可调节神经元活性。
S3588	Hexylene glycol	Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂，已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。
S3595	D-Gluconic acid	D-Gluconic acid 是一种抗真菌 antifungal 药。
S6446	Sodium citrate dihydrate	Sodium citrate dehydrate (Trisodium citrate dihydrate, Citric acid trisodium salt dihydrate) 是一种首选的抗凝血剂。
S3594	Adipic acid	Adipic acid (Hexanedioic acid) 是一种重要的二羧酸，可用于制造尼龙和聚氨酯塑料。
S3596	Polyvinylpyrrolidone	Polyvinylpyrrolidone (PVP, Polyvidone, Povidone) 是一种惰性的、水溶性的、无毒的、耐温且pH稳定的、具有生物相容性的、可生物降解的聚合物，有助于封装和满足亲水性和亲脂性药物的需求。Polyvinylpyrrolidone 已被广泛测试并用作有效的伤口愈合促进剂。
S3598	Sucrose	Sucrose (D-(+)-Saccharose) 是植物天然产生的一种常见糖，是一种二糖，由两个单糖：葡萄糖和果糖组成的分子。
S4424	Hyaluronidase	Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) 是一种天然酶，可降解透明质酸，而透明质酸是细胞外基质的重要组成部分。
S0235	Lavendustin B	Lavendustin B 抑制 HIV-1 integrase (IN) 与其同源的细胞辅助因子 lens epithelium-derived growth factor (LEDGF/p75) 的相互作用。Lavendustin B 是 Tyrosine Kinase 的抑制剂，也是 glucose transporter 1 (Glut1) 的竞争性抑制剂。
S9794	Melittin	Melittin (MLT, Forapin, Forapine) 是 phospholipase A2 (PLA2) 的活化剂，可刺激低分子量PLA2的活性，但不会增加高分子量酶的活性。
S3168	cis-Resveratrol	cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) 是Resveratrol的顺式异构体。Resveratrol 是一种天然的酚类化合物，具有抗氧化、抗炎、保护心脏和抗癌的特性。Resveratrol 是 pregnane X receptor (PXR) 的抑制剂，也是 Nrf2 和 SIRT1 的激活剂，并可能诱导凋亡。Resveratrol 还可抑制多种靶标，包括 5-lipoxygenase (LOX)、cyclooxygenase (COX)、IKKβ、DNA polymerases α和δ，IC50分别为2.7 μM、<1 μM、1 μM、3.3 μM和5 μM。
S3499	Monocaprylin	Monocaprylin (2,3-dihydroxypropyl octanoate, Monoctanoin, 1-Octanoyl-rac-glycerol, MC) 对金黄色葡萄球菌和大肠杆菌具有优异的抗菌活性。
S0921	Wilforine	Wilforine (WR) 是在wilfordii植株中发现的倍半萜吡啶生物碱，可显著地抑制 P-glycoprotein (P-gp) 的外排活性。
S3351	Sodium phenylpyruvate	Sodium phenylpyruvate (Phenylpyruvic acid sodium salt) 可抑制氨基酸形成 amino acid formation 并降低氧气消耗。
S2995	4-Hydroxyphenylpyruvic acid	4-Hydroxyphenylpyruvic acid (4-HPPA) 是一种丰富的多酚结肠代谢产物，是一种有效的清除剂，可抑制 free radicals 和 cyclooxygenase-2 (COX-2) 的水平，并有助于降低结肠癌发展的风险。
S6918	Oleandrin (PBI-05204)	Oleandrin (PBI-05204, Foliandrin, Neriolin, Neriostene, Folinerin, Corrigen, Neriol) 是 Na+/K+-ATPase 的抑制剂，IC50值为0.62 μM。Oleandrin 可诱导凋亡并减少人胶质瘤细胞的体外迁移。
S6990	Phytohemagglutinin	Phytohemagglutinin (PHA, Phaseolus vulgaris agglutinin) 在毕赤酵母中利用天然信号肽或酿酒酵母α-因子前体序列表达，将蛋白质引导至分泌途径。Phytohemagglutinin 可通过增加凋亡蛋白 Bax 和激活 caspases-3 来诱导人HEp-2癌细胞的凋亡。
P1201	LL37 (Human cathelicidin)	LL37 (Human cathelicidin, Ropocamptide) 是与Cathelicidin相关的 antimicrobial 抗菌肽，具有强大的趋化和免疫调节特性。
S3069	Deoxycholic acid sodium salt	Deoxycholic acid sodium salt (Sodium Deoxycholate, Sodium Desoxycholate, Cholanoic Acid, ATX-101, Kythera, Belkyra, DCA) 会特定地激活刺激棕色脂肪组织(BAT)的 TGR5 receptor (GPCR19) 的产热活动。
S3248	2'-Deoxyadenosine 5'-monophosphate	2'-Deoxyadenosine 5'-monophosphate (5'-dAMP) 是一种内源性代谢产物，仅在酸性条件下被光敏降解。
S3268	2'-Deoxycytidine 5'-monophosphate	2'-Deoxycytidine-5'-monophosphoric acid (dCMP) 是一种内源性代谢产物，可以用作描述由二次电子诱导的DNA链断裂机理的模型，并且主要通过C-O磷酸酯键的解离而分解。
S3318	N-Acetyl-L-arginine dihydrate	N-Acetyl-L-arginine (Ac-Arg-OH) dihydrate 是一种内源性代谢产物。
S3319	Levoglucosan	Levoglucosan (LG, LEV, Leucoglucosan, Glucosan, 1,6-anhydro-b-D-Glucose) 是一种内源性代谢产物。
S3324	Sodium 2-(1H-indol-3-yl)acetate	Sodium 2-(1H-indol-3-yl)acetate (3-Indoleacetic acid sodium, Indole-3-acetic acid sodium, 3-IAA sodium) 是一种内源性代谢产物。
S3326	Phytic acid dipotassium salt	Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)) 是一种稻谷提取物和消化物中的内源性代谢物，可抑制 β-secretase 1 (BACE1)，其IC50值约为0.25 μM。
S3331	2-Aminoethylphosphonic acid	2-Aminoethylphosphonic acid (2-AEP, (2-Aminoethyl)phosphonic acid) 是一种丰富而普遍存在的天然膦酸酯，被许多原核谱系用作磷源。
S3335	Phospho(enol)pyruvic acid monopotassium salt	Phospho(enol)pyruvic acid monopotassium salt (Potassium 1-carboxyvinyl hydrogenphosphate) 是一种内源性代谢产物。
S3343	Methyl β-D-Galactopyranoside	Methyl β-D-Galactopyranoside (Methyl beta-D-galactoside, Methylgalactoside) 是一种内源性代谢物。
S3370	3-Methoxytyramine hydrochloride	3-Methoxytyramine (3-O-methyl Dopamine, 3MT) hydrochloride 是多巴胺的主要细胞外代谢产物，是一种神经调节剂，在某些情况下可能参与运动控制。
S3310	D-(+)-Galacturonic acid monohydrate	D-(+)-Galacturonic acid monohydrate (D-Galacturonic acid hydrate, d-GalA, D-galUA) 是一种内源性代谢产物，可用于工程酿酒酵母中。
S3323	2-Hydroxycaproic acid	2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) 是一种内源性代谢产物。
S2997	DL-Tartaric acid	DL-Tartaric Acid (2,3-Dihydroxysuccinic acid) 是一种白色结晶有机酸，可从许多植物中，特别是罗望子树tamarinds和葡萄grapes中分离出来，并用作抗氧化剂和添加剂，以赋予酸味。
S3087	N-Acetyl-DL-methionine	N-Acetyl-DL-methionine 是一种活性内源性代谢产物，可降低雄性Bom:NMRI mice的肝脏 glutathione 水平。
S3092	Glyoxylic acid monohydrate	Glyoxylic acid monohydrate (2,2-Dihydroxyacetic acid) 是一种与大气有关的酮酸。
S3093	Pyrazole	Pyrazole (1H-pyrazole) 是具有两个氮原子的五元杂芳族环，具有重要意义。Pyrazole 是设计和开发新药理学必不可少的支柱。
S3094	N-Acetyl-L-alanine	N-Acetyl-L-alanine (NAAL, Ac-Ala-OH) 是一种活性内源性代谢产物。
S3157	3-Hydroxybenzaldehyde	3-Hydroxybenzaldehyde (3-HBA) 是自然界中常见的一种苯甲醛，由 3-hydroxybenzyl-alcohol 脱氢酶产生，并且是大鼠和人体中醛脱氢酶(ALDH)的底物。3-Hydroxybenzaldehyde 具有血管保护作用。
S3315	6-Hydroxyindole	6-Hydroxyindole (1H-indol-6-ol) 是一种内源性的有效且持久的 OATP1B1 的抑制剂，其IC50值约为10 μM。
S3334	Glycolaldehyde dimer	Glycolaldehyde dimer (2,5-Dihydroxy-1,4-dioxane, 1,4-Dioxane-2,5-diol, DD) 是一种活性内源性代谢产物，当与甘氨酸(Gly)或硫酸铵(AS)反应时，具有中等吸收性和荧光性。
S3336	Heptadecanoic acid	Heptadecanoic acid (C17:0) 是一种奇数链饱和脂肪酸，可显著地抑制细胞增殖和迁移，同时促进PC-9和PC‑9/GR细胞的凋亡。Heptadecanoic acid 与多种疾病相关，包括冠心病，前驱糖尿病和2型糖尿病以及多发性硬化症的发生率。
S3337	L-Histidinol dihydrochloride	L-Histidinol dihydrochloride 是必需氨基酸L-组氨酸的结构类似物，是一种 protein biosynthesis 的可逆抑制剂，它引起培养中非致瘤和致瘤细胞的不同反应。
S3338	D-(-)-Lyxose	D-(-)-Lyxose (D-Lyxose) 是一种活性内源性代谢产物。
S3345	Nα-Acetyl-L-lysine	Nα-Acetyl-L-lysine (Ac-Lys-OH, N(alpha)-Acetyllysine) 是一种活性内源性代谢物。
S3347	3-Methylglutaric acid	3-Methylglutaric acid (MGA, 3MG acid) 是一种明显的C6二羧酸有机酸，可以用作单一的固态NMR标准化合物来执行除磁体匀场之外的所有校准步骤。
S3348	O-Acetyl-L-serine hydrochloride	O-Acetyl-L-serine (OAS, O-Acetylserine, O-Acetyl-L-serine) hydrochloride (HCl) 是一种细菌和植物中氨基酸半胱氨酸生物合成的中间体，其显示出一种信号功能，不论植物的硫状态如何，它都能改变特定基因的转录水平。
S3358	4-Acetamidobutyric acid	4-Acetamidobutanoic acid (N-acetyl GABA) 是一种 Gamma-aminobutyric acid (GABA) 的衍生物，由GABA氮原子的单乙酰化产生。
S3360	Bis(2-ethylhexyl) phthalate	Bis(2-ethylhexyl) phthalate (Dioctyl phthalate, DOP, Diplast O, ESBO-D 82, Ergoplast FDO, Ergoplast FDO-S, Etalon) 可诱导幼虫斑马鱼 Danio rerio 中的 DNA strand breaks 和基因表达改变。
S3095	Itaconic acid	Itaconic acid 是一种巨噬细胞特异性 (Mϕ-specific) 代谢产物，可介导巨噬细胞代谢与腹膜肿瘤之间的交互作用。Itaconic acid 还是聚合物，化学品和燃料的前体，可以由许多真菌合成。
S3096	L-Histidine monohydrochloride monohydrate	L-Histidine monohydrochloride monohydrate (L-Histidine hydrochloride hydrate, H-His-OH.HCl.H2O) 是必需氨基酸L-组氨酸的结构类似物，是 protein biosynthesis 的可逆抑制剂，可引起培养中非致瘤细胞和致瘤细胞的不同反应。
S3098	N-Acetylglycine	N-Acetylglycine (NAGly, Aceturic acid, Acetamidoacetic acid) 是许多食品的次要成分，没有遗传毒性或急性毒性。
S3097	5,6-Dimethylbenzimidazole	5,6-Dimethylbenzimidazole (5,6-DMB, Dimezol, Dimedazol, 5,6-Dimethyl-1H-benzo[d]imidazole, 5,6-Dimethyl-1H-benzimidazole) 是一种维生素B12的前体。
S3107	D-Pyroglutamic acid	D-Pyroglutamic acid (D-5-Oxoproline, D-Pyr-OH, 5-oxo-D-proline, (R)-5-Oxopyrrolidine-2-carboxylic acid) 是一种有效的内源性代谢产物，可对抗由N-methyl-D-aspartate receptor拮抗剂 AP-5 诱导的被动回避行为的中断。
S3109	N-Acetyl-L-leucine	N-acetyl-L-leucine 是一种有效的内源性代谢产物，通过在小脑和丘脑中起作用，加速单侧迷路切除后前庭代偿。
S3111	Pyridoxal hydrochloride	Pyridoxal hydrochloride (HQ) 是一种活性内源性代谢产物。
S3365	(S)-(-)-1-Phenylethanol	(S)-(-)-1-Phenylethanol ((S)-1-Phenylethanol, (S)-(-)-Phenylethanol) 是一种具有风味特性的1-Phenylethanol的对映异构体。
S3366	Monoethyl malonic acid	Monoethyl malonic acid (Ethyl hydrogen malonate, Monoethyl malonate, 3-Ethoxy-3-oxopropanoic acid) 是 ethyl 3-ethoxypropionate (EEP) 的主要尿代谢产物。
S3320	(R)-3-Hydroxybutanoic acid	(R)-3-Hydroxybutanoic acid (R-3HB, D-3-hydroxybutyric acid) 是PHB (poly[(R)-3-hydroxybutyrate])的单体，具有广泛的工业和医学应用。(R)-3-Hydroxybutanoic acid 也可以用作合成纯的可生物降解的PHB及其共聚酯的手性前体。
S3049	Calcium 2-hydroxy-4-(methylthio)butanoate	Calcium 2-hydroxy-4-(methylthio)butanoate 是一种活性内源性代谢物。
S3135	2-Amino-1-phenylethanol	2-Amino-1-phenylethanol (2-APE) 是一种去甲肾上腺素类似物。
S3221	Thymidine 5'-monophosphate disodium salt	Thymidine-5'-monophosphate (5'-Thymidylic acid) disodium salt 是一种活性内源性代谢物。
S3311	Myosmine	Myosmine 是次要的烟草生物碱之一，并存在于各种食品中。Myosmine 对 a4b2 nicotinic acetylcholinergic receptors (nAChR) 具有低亲和力，Ki为3300 nM。
S3321	N-Methylnicotinamide	N-Methylnicotinamide (MNA, Nicotinyl Methylamide, N-Methyl-3-pyridinecarboxamide) 是一种活性内源性代谢产物，可通过调节ADMA-DDAH轴改善内皮功能障碍并减轻动脉粥样硬化。
S3325	L-Cysteic acid monohydrate	L-Cysteic acid monohydrate (CAM) 是一种活性内源性代谢物。
S3329	(L)-Dehydroascorbic acid	(L)-Dehydroascorbic acid (DHA) 是一种l-Ascorbic acid (AsA)的氧化形式，其在硫醇的存在下可有效地清除非热等离子体诱导的羟基自由基，而自身不能清除羟基自由基。
S3342	Petroselinic acid	Petroselinic acid (PSA) 是一种从香菜果实的植物油中分离出来的油酸的位置异构体。Petroselinic acid 可用于新槐糖脂的发酵。
S3344	Serotonin creatinine sulfate monohydrate	Serotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate 是一种活性内源性代谢产物。
S3346	1-Methylnicotinamide chloride	1-Methylnicotinamide (1-MNA, 3-Carbamoyl-1-methylpyridin-1-ium, Trigonellamide) chloride 是烟酰胺的活性内源性代谢产物，具有抗炎和抗血栓形成的作用。1-Methylnicotinamide 可增强肿瘤血管的形成，并显著地增加 prostacyclin (PGI2) 的生成。
S3349	Phosphocholine chloride calcium salt tetrahydrate	Phosphocholine (Phosphorylcholine) chloride calcium salt tetrahydrate 是一种活性内源性代谢物。
S3350	Cholesteryl linoleate	Cholesteryl linoleate 是一种人鼻液中极性较低的脂质，助力固有的抗菌活性。
S3352	Tricosanoic acid	Tricosanoic acid 是一种脂族羧酸，具有很强的生发作用。
S3353	Lithium acetoacetate	Lithium acetoacetate (LiAcAc, Acetoacetic acid lithium salt, Lithium 3-oxobutanoate) 是一种活性内源性代谢产物，可影响细胞系的生长。Lithium acetoacetate 可用作乙酰乙酸盐标准品，用于测量生物样品中的乙酰乙酸。
S3354	DL-2,3-Diaminopropionic acid monohydrochloride	DL-2,3-Diaminopropionic acid monohydrochloride (2,3-Diaminopropanoic acid hydrochloride) 是一种活性内源性代谢物。
S3355	3-Hydroxyanthranilic acid	3-Hydroxyanthranilic Acid (3-HAA, 3-HANA)是一种色氨酸代谢物具有免疫调节作用，可能是通过抑制 PI3K/Akt/mTOR 和 NF-κB 活性，减少促炎性介质的产生。
S3356	Phosphonoacetic acid	Phosphonoacetic acid (PAA) 是一种活性内源性代谢产物，具有限制 DNA biosynthesis 的潜力。Phosphonoacetic acid 具有抗病毒的活性。
S3357	Elaidic acid	Elaidic acid 是一种主要的反式脂肪酸，可抑制细胞活力，并通过增强氧化应激 oxidative stress 来促进细胞的凋亡。Elaidic acid 可用作药物溶剂。
S3359	Isomaltulose hydrate	Isomaltulose (Palatinose) hydrate 是一种 disaccharide carbohydrate，广泛应用于在运动期间维持血糖和水合作用。
S3361	(3-Carboxypropyl)trimethylammonium chloride	(3-Carboxypropyl)trimethylammonium chloride (γ-Butyrobetaine, γBB hydrochloride) 是小鼠饮食中L-carnitine被肠道微生物分解的中间代谢产物。
S3362	D-Gulonic acid γ-lactone	D-Gulonic acid γ-lactone (Gulonolactone, D-Gulono-1,4-lactone, 1,4-D-Gulonolactone) 是一种活性内源性代谢物。
S3363	DL-Mandelic acid	DL-Mandelic acid (MA, 2-Hydroxy-2-phenylacetic acid, Amygdalic acid, Almond acid) 可通过阴离子交换反应嵌入到Zn-Al层状双氢氧化物(LDH)中，从而构建新型的抗菌分层材料。
S3367	cis-4-Hydroxy-D-proline	cis-4-Hydroxy-D-proline (H-D-cis-Hyp-OH) 是一种内源性代谢产物，可用于研究D-丙氨酸脱氢酶的特异性和动力学。
S3368	Uridine-5'-diphosphate disodium salt	Uridine-5'-diphosphate (UDP) disodium salt 是一种有效的、选择性的 P2Y₆ receptor 的天然激动剂，其EC50值为300 nM，pEC50值为 6.52。Uridine-5'-diphosphate (UDP) disodium salt 也是 P2Y₁₄ receptor 的拮抗剂，pEC50值为 7.28。
S3371	N-Acetyl-D-mannosamine	N-Acetyl-D-mannosamine (ManNAc, N-acetyl-beta-mannosamine) 是唾液酸的前体，可改善年龄相关的突触传递和长期增强(LTP)的衰减。N-Acetyl-D-mannosamine 的治疗是认知功能障碍的潜在治疗应用。
S3088	(±)-Methyl Jasmonate	(±)-Methyl Jasmonate (MeJA, Methyl jasmonate, Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate)，是一种植物激素，在植物中起着至关重要的细胞调节剂的作用，是调节炎症性肠病(IBDs)的新候选药物，可调节 caspase 型蛋白酶家族主要类型的表达。
S3169	2'-Deoxyuridine 5'-monophosphate disodium salt	2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP) 是胸苷酸合酶的底物，并可被转化为deoxythymidine monophosphate (dTMP)。在甲基化步骤中，dUMP对dTMP的抑制作用是控制细菌和真核细胞生长的关键。
S3322	Nicotinuric acid	Nicotinuric acid (NUA) 是烟酸的主要排毒产物，可以作为烟酸在肝脏生物转化中的简单定量指标。
S3332	D-Mannosamine hydrochloride	D-Mannosamine hydrochloride ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride) 是一种活性的内源性代谢产物。
S3364	3-Hydroxyphenylacetic acid	3-Hydroxyphenylacetic acid (3-HPAA) 是一种酚酸，主要存在于橄榄油废水中，也是膳食类黄酮槲皮素flavonoid quercetin的肠道代谢产物。3-Hydroxyphenylacetic acid 具有抗菌性能。
S3040	Isocitric acid trisodium salt	Isocitric acid (DL-Isocitric acid) trisodium salt 是一种活性的内源性代谢产物。
S3089	12-Hydroxydodecanoic acid	12-Hydroxydodecanoic acid (G12) 是一种活性内源性代谢产物。
S3341	Palmitoleic acid	Palmitoleic acid (POA, Palmitoleate) 可通过依赖于PPARα的 AMPK 和 FGF-21 活化来刺激肝脏中葡萄糖的摄取。
S2989	Nα-Acetyl-L-asparagine	Nα-Acetyl-L-asparagine (N-Acetylasparagine, (S)-2-acetamido-4-amino-4-oxobutanoic acid) 是一种存在于人脑中的内源性代谢产物。
S2991	Thiamine monophosphate chloride dihydrate	Thiamine monophosphate chloride dihydrate (Vitamin B1 Monophosphate Chloride, Sineurina, Phosphothiamine) 是一种内源性代谢物。
S2992	Sodium mesoxalate monohydrate	Sodium mesoxalate monohydrate (sodium 2,2-dihydroxymalonate) 是一种内源性代谢产物。
S2993	D-Saccharic acid potassium salt	D-Saccharic acid potassium salt (D-Glucaric acid potassium, Potassium bisaccharate) 是一种内源性代谢产物。
S2999	Acetic acid octyl ester	Acetic acid octyl ester (Octyl acetate) 是野生 parsnip (Pastinaca sativa) 的外壳或油管中精油的主要成分之一。Acetic acid octyl ester 具有抗氧化活性。
S3006	Methyl isoeugenol	Methyl isoeugenol (Methylisoeugenol) 是从 Acori Tatarinowii Rhizoma 分离得到的丁香酚类似物异丁香酚。Methyl isoeugenol 是一种对Z. diversus极具吸引力的诱剂，可作为监控和雄性灭计划中的引诱剂。
S3009	Menthone	Menthone 是薄荷精油(Mentha piperita L.)的主要挥发性成分之一。Menthone 可用作抗氧化剂，具有良好的补偿作用，可显着减少精子细胞中的 DNA damages。
S3091	Methyl acetoacetate	Methyl acetylacetate (MAA, Acetoacetate methyl ester, Methyl 3-oxobutanoate, Methyl 3-oxobutyrate, Methyl acetoacetate, Methyl acetylacetate) 是一种内源性代谢产物，可用作合成药物的化学试剂。
S2998	Isophorone	Isophorone (IPHO) 是一种α,β-不饱和环状酮，是一种透明的液体，带有樟脑样的气味。Isophorone 可用作聚合物的前体。
S3313	Nudifloric Acid	Nudifloric acid (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid)，是从一种抗氧化、抗癌、抗炎、抗糖尿病、抗肥胖、抗血管生成和抗伤害感受活动飞虫草 Cordyceps bassiana 中分离出来的。
S3317	cis-3-Hexenyl hexanoate	Cis-3-Hexenyl hexanoate ((Z)-3-hexenyl hexanoate) 是一种植物挥发物，可将热带和果肉风味与柑橘和绿色细腻感带入各种水果风味。
S3327	Disodium 5'-inosinate monohydrate	Disodium 5'-inosinate monohydrate (Inosine 5'-monophosphate disodium salt hydrate) 是一种内源性代谢物。
S3333	(2R,3R)-(-)-2,3-Butanediol	(2R,3R)-(-)-2,3-Butanediol ((2R,3R)-Butane-2,3-diol) 是内源性代谢产物。
S2990	Dihydroxyfumaric acid hydrate	Dihydroxyfumaric acid hydrate (DHF) 是一种内源性代谢物。Dihydroxyfumaric acid hydrate (DHF) 的二酯衍生物已专门用作有机合成中的亲电子试剂。
S2988	DL-5-Hydroxylysine hydrochloride	DL-5-Hydroxylysine hydrochloride 是一种内源性代谢产物，是5-羟基赖氨酸D-和L-对映体的外消旋混合物，可用作自由基诱导的蛋白质氧化的潜在靶标。
S2994	DL-Homocysteine	DL-Homocysteine 是一种弱神经毒素，会影响脑中 kynurenic acid (KYNA) 的产生。DL-Homocysteine 可抑制KYNA生物合成酶、kynurenine aminotransferases (KATs) I和II的活性。
S3099	δ-Valerolactone	δ-Valerolactone (Tetrahydro-2H-pyran-2-one, 5-Valerolactone, oxan-2-one) 是一种内源性代谢物。
S3328	N-Formyl-L-methionine	N-Formyl-L-methionine (For-Met-OH) 是一种内源性代谢产物。
S6955	Insulin (human)	Insulin (human) (Insulin regular) 是一种调节葡萄糖水平的多肽激素。Insulin 通常用于治疗糖尿病患者的高血糖症。效价(potency)：29 units/mg。
S2986	9-Methoxycanthin-6-one	9-Methoxycanthin-6-one 是存在于完整的植物部分和不同外植体的愈伤组织中的具有抗肿瘤活性的成分。
S3108	2,5-Dimethylpyrazine	2,5-Dimethylpyrazine (NSC 49139) 是一种内源性代谢产物。
S2996	L-DAB HBR	L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) 是一种 GABA (Gamma-aminobutyric acid) transaminase 的抑制剂，IC50值大于500 μM。L-DAB HBR 表现出抗肿瘤活性。
S3029	Malonic acid	Malonic acid (MOA) 是气溶胶中的主要dicarboxylic acids (DCAs)之一，通过实验和计算得出，它是一种强酸。Malonic acid (MOA) 可充当形成基于SA-A的纯簇的中介桥。
S3086	Maleic acid	Maleic acid 可抑制 glutamate decarboxylase (GAD) 的活性，从而增强 Listeria monocytogenes 的酸敏感性。Maleic acid 会影响细胞外 GABA 的水平。
S3090	trans-Aconitic acid	trans-Aconitic acid (TAA) 是Echinodorus grandiflorus（一种在巴西用于治疗类风湿性关节炎的药用植物）的叶子中的丰富成分。
S3101	2-Deoxy-D-ribose	2-Deoxy-D-ribose (Thyminose, Deoxyribose) 是一种内源性代谢产物。
S3118	L-Homoserine	L-Homoserine (L-Hse) 是苏氨酸，蛋氨酸和赖氨酸的重要生物合成中间体。
S3123	3-Methyl-2-buten-1-ol	3-Methyl-2-buten-1-ol (Prenol, Prenyl alcohol, Dimethylallyl alcohol) 是一种内源性代谢产物。
S3143	Pyruvic acid	Pyruvic acid (Acetylformic acid) 是一种重要的有机化学中间体，在心肌细胞的病理生理和治疗中发挥作用。Pyruvic acid 可显着提高 lactate dehydrogenase (LDH) 和 creatine kinase (CK) 的水平，并降低 Ca²⁺Mg²⁺-ATPase 和 Na⁺K⁺-ATPase 的水平。
S3084	Guanosine 5'-triphosphate trisodium salt	Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt 是鼠细胞中成肌细胞分化的增强剂。Guanosine 5'-triphosphate trisodium salt 可上调miRNA（特别是miR133a和miR133b）和肌原性调节因子，并诱导人肌原性前体细胞在细胞外环境中释放出被鸟苷基分子（主要是鸟苷）填充的外泌体。
S3125	N-Formylglycine	N-Formylglycine (2-formamidoacetic acid, For-Gly-OH, FGly) 是一种内源性代谢产物。
S3126	Sodium 2-hydroxybutanoate	Sodium 2-hydroxybutanoate (Sodium 2-hydroxybutyrate, Sodium DL-2-hydroxybutyrate)是由2-氨基丁酸转化而成的一种中间代谢物。
S3127	2,4-Dihydroxypyrimidine-5-carboxylic acid	2,4-Dihydroxypyrimidine-5-carboxylic Acid (Uracil 5-carboxylic acid, Isoorotic acid, 5-Carboxyuracil) 是一种内源性代谢产物。
S3128	N-Acetyl-D-galactosamine	N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) 是一种内源性代谢物。
S3131	L-(-)-Glucose	L-Glucose (L-(-)-Glucose) 是D-葡萄糖的对映异构体。L-Glucose 可促进食物摄取，而细胞不能将其用作能量来源，因为它不能被己糖激酶磷酸化。
S3134	D-(-)-Tartaric acid	D-(-)-Tartaric acid 是酒石酸的非天然异构体，它是具有广泛的工业和科学应用的重要手性化学构件。
S3141	Maleimide	Maleimide 显示出荧光猝灭能力，并且可以作为荧光探针用于硫醇分析物的特异性检测。Maleimide 还用于生产抗体偶联药物(ADC)，用于癌症研究。
S3142	Potassium sorbate	Potassium sorbate (Sorbic acid potassium) 是一种无毒的食品防腐剂，它是从 Sorbus aucuparia 中分离出来的。Potassium sorbate 是大多数霉菌，酵母菌和某些细菌的有效抑制剂。
S3145	Pimelic acid	Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) 是源自脂肪酸合成途径的枯草芽孢杆菌中生物素的前体。
S3152	Glutaric acid	Glutaric acid (GA) 是一种有吸引力的C5二羧酸，在生物化学工业中具有广泛的应用。
S3159	Citraconic acid	Citraconic acid (CA) 是一种存在于野生大豆中的甲基支链脂肪酸。
S3316	5-Hydroxy-1-tetralone	5-hydroxy-1-tetralone 是一种荧光标记 fluorescent labeling 的试剂，用于从少量生物样品中测定糖鞘脂。
S3330	Maleamic acid	Maleamic acid ((Z)-4-Amino-4-oxobut-2-enoic acid) 是一种内源性代谢产物。
S3339	3-(2-Hydroxyphenyl)propionic acid	3-(2-Hydroxyphenyl)propanoic acid (Melilotic acid, Melilotate, 2-hydroxybenzenepropanoic acid) 是一种内源性代谢产物。
S2987	4-Methyl-2-oxovaleric acid	4-Methyl-2-oxovaleric acid (Ketoleucine, 4-MOV, KIC, 4-Methyl-2-oxopentanoic acid, alpha-Ketoisocaproic acid, alpha-ketoisocaproate, 2-Oxoisohexanoate) 是由星形胶质细胞释放至神经元，可以通过氨基转移酶重新形成亮氨酸。4-Methyl-2-oxovaleric acid 可降低骨骼肌中蛋白质的降解速率。4-Methyl-2-oxovaleric acid 可通过抑制 alpha-ketoglutarate dehydrogenase (oxoglutarate dehydrogenase complex, OGDC) 的活性来发挥 oxidative phosphorylation (OXPHOS) 的解偶联剂和代谢抑制剂的功效。
S3266	L-Anserine nitrate salt	L-Anserine nitrate salt 是一种存在于大多数动物组织中的二肽，具有抗氧化、抗交联和抗糖基化的作用。L-Anserine 可防止内质网应激诱导物诱导的神经毒性。
S1273	Amarogentin	Amarogentin (AG) 是一种主要从 Swertia 和 Gentiana 根中提取的裂环烯醚苷，具有抗氧化、抗肿瘤和抗糖尿病的作用。Amarogentin 是苦味受体 TAS2R1 的激动剂，可抑制LAD-2细胞中substance P诱导的新合成的 TNF-α 的产生。Amarogentin 通过 G2/M 细胞周期的阻滞和 PI3K/Akt 信号通路诱导人胃癌细胞（SNU-16）的凋亡。Amarogentin (AG) 可与 AMP-activated protein kinase (AMPK) 的α2亚基相互作用，并激活三聚体激酶，其EC50值为277 pM。
S0923	Isoliquiritin apioside	Isoliquiritin apioside (ISLA, ILA) 是一种分离自 Glycyrrhizae radix rhizome (GR) 的成分，可显著地降低PMA诱导的 matrix metalloproteinase (MMP) 的活性增加并抑制了PMA-诱导 mitogen-activated protein kinase (MAPK) 和 NF-κB 的活化。Isoliquiritin apioside 在恶性癌细胞和EC中具有抗转移和抗血管生成的能力，并且没有细胞毒性。
S2869	Adamantane	Adamantane 是一种无色结晶的、带有类似樟脑气味的化合物，首次获得是从石油中分离出的。Adamantane 可用于治疗 influenza A virus 感染。
S9690	Caerulein (FI-6934)	Caerulein (Ceruletide, Cerulein, FI-6934) 是一种 cholecystokinin (CCK) receptor 的激动剂，也是一种安全有效的胆囊代谢药，是小肠和胰腺外分泌的兴奋剂。
S6924	D-Luciferin sodium salt	D-Luciferin (D-(-)-Luciferin, Firefly luciferin) sodium salt 是萤光素酶的天然底物，可催化生物发光昆虫产生光。
S3290	Procyanidin B2	Procyanidin B2 (PCB2) 是一种存在于常见食品中的天然类黄酮，具有抗炎、抗氧化和抗癌活性。Procyanidin B2 可激活 PPARγ 并诱导小鼠巨噬细胞M2极化。Procyanidin B2 可显著抑制百草枯在大鼠模型中肺组织中 NLRP3 炎性小体的活化。
S9700	Tapinarof	Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) 是一种 aryl hydrocarbon receptor (AhR) 的天然激动剂，可诱导永生化角质形成细胞(HaCaT)中AhR的核易位，EC50值为0.16 nM。Tapinarof 可以以剂量依赖的方式诱导CD4+ T细胞的凋亡，其IC50值为5.2 μM。
S6919	Brevilin A	Brevilin A (6-O-Angeloylplenolina) 是一种从Centipeda minima分离得到的倍半萜内酯，是 STAT3 的选择性抑制剂，可通过阻断JAKs酪氨酸激酶结构域 JH1 来减弱 JAKs 的活性。Brevilin A 可通过线粒体途径和 PI3K/AKT/mTOR 失活来诱导结肠腺癌细胞CT26的凋亡和自噬。
S0924	Pteryxin	Pteryxin ((+)-Pteryxin) 是一种在 Apiaceae 伞形科中发现的二氢吡喃香豆素衍生物，也是一种有效的 butyrylcholinesterase (BChE) 的抑制剂，IC50值为12.96 μg/ml。Pteryxin 可抑制LPS诱导的小鼠腹膜巨噬细胞中 nitric oxide 的产生，其IC50值为20 μM。Pteryxin 具有治疗阿尔茨海默氏病 (AD) 的潜力。
S0973	Wilforgine	Wilforgine 是 Tripterygium wilfordii Hook. F.中主要的生物活性倍半萜生物碱之一，可在M. separata larvae的肌肉中诱导显微结构和超微结构变化，其发挥作用的位置是肌肉系统中的 calcium receptors or channels。
S3254	Plantagoside	Plantagoside 是一种从 Plantago asiatica 的种子中分离出的黄烷酮葡糖苷，是一种特异性的、非竞争性的 alpha-mannosidase 的抑制剂，IC50值为5 μM。
S3253	Xylobiose	Xylobiose (1,4-β-D-Xylobiose, 1,4-D-Xylobiose) 是由木糖单体形成的二糖，是一种天然的底物，可以被来源于 Selenomonas ruminantium (SXA)的β-D-木糖苷酶/α-L-阿拉伯呋喃糖苷酶水解。
S3252	Xylotriose	Xylotriose (1,4-b-D-Xylotriose, 1,4-beta-D-xylotriose) 是一种天然的木寡糖底物，可以被来源于 Selenomonas ruminantium (SXA)的催化有效的β-D-木糖苷酶水解。
S3222	Raspberry ketone glucoside	Raspberry ketone glucoside (RKG) 是来源于树莓果实的天然产物，是一种抗氧化剂antioxidant，对黑色素 melanin 的合成具有抑制作用。
S3223	L-Quebrachitol	L-Quebrachitol (L-QCT) 是可从许多植物中分离出来的天然产物，促进增殖和细胞DNA合成。L-Quebrachitol 可上调 bone morphogenetic protein-2 (BMP-2)、runt-related transcription factor-2 (Runx2) 和 mitogen-activated protein kinase (MAPK) 相关调控基因和 Wnt/β-catenin 信号通路，同时下调 nuclear factor-κB(NF-κB) 配体 (RANKL) 受体激活剂的mRNA水平。
S3226	Dehydroabietic acid	Dehydroabietic acid (DAA, DHAA) 是一种天然的二萜树脂酸，衍生自针叶植物（如 Pinus 和 Picea）通过抑制 Src、Syk 和 TAK1 介导的通路来产生抗炎活性。
S3278	Kaempferol-3-O-neohesperidoside	Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside) 是一种从Primula latifolia Lapeyr. 和 Primula vulgaris Hudson 的叶提取物中分离出的类黄酮，通过 PI3K - GSK-3 信号通路和 MAPK - PP1 通路来刺激大鼠比目鱼肌中的糖原合成 glycogen synthesis。
S3289	Daphnoretin	Daphnoretin (Dephnoretin, Thymelol) 是一种从Wikstroemia indica C.A. Mey.中提取的具有生物活性的化合物，是 protein kinase C (PKC) 的激活剂。Daphnoretin 通过调节 Akt 信号通路的活性，来抑制肿瘤细胞的增殖、侵袭和迁移，促进其凋亡。
S3295	Taxifolin 7-rhamnoside	Taxifolin 7-rhamnoside (TR, Taxifolin 7-O-rhamnoside, Taxifolin 7-O-α-L-rhamnoside) 是一种从 Hypericum japonicum 中分离出的类黄酮，其具有对抗耐甲氧西林金黄色葡萄球菌 (MRSA).的临床分离株的抗菌活性。
S3224	Cinobufagin	Cinobufagin (Cinobufagine) 是 Venenum Bufonis 的活性成分，可抑制肿瘤发展。Cinobufagin 可提高 ATM 和 Chk2 并降低 CDC25C、CDK1 和 cyclin B。Cinobufagin 抑制 PI3K、AKT 和 Bcl-2，同时增加裂解的 caspase-9 和 caspase-3 水平。由此诱导细胞周期停滞在G2/M期及凋亡。
S3230	L-Fucitol	L-Fucitol (1-Deoxy-D-galactitol) 是一种分离自 Myristica fragrans (Nutmeg) 的半乳糖醇类似物，可抑制大肠杆菌K12的半乳糖醇阳性菌株。
S3233	Emetine hydrochloride	Emetine hydrochloride (NSC 33669) 是一种从吐根 ipecac 根部提取的主要生物碱，在临床上被用作催吐和抗原生动物药物，可降低 HIFs (hypoxia-inducible factors; HIF-1α and HIF-2α)、PDK1、RhoA、Rho-kinases (ROCK1 and ROCK2) 和 BRD4。Emetine hydrochloride 可抑制细胞的自噬，并具有抗疟疾、抗病毒、抗细菌和抗变形虫的作用。已取得危险化学品经营许可
S3236	Mesaconitine	Mesaconitine 是Aconiti tuber附子块茎中的附子生物碱之一，通过从细胞外空间流入Ca2+来增加内皮细胞中的[Ca2+]i水平。
S3238	Resibufogenin	Resibufogenin (Bufogenin, Recibufogenin) 是huachansu华蟾素中具有抗癌作用的成分，通过上调 receptor-interacting protein kinase 3 (RIP3) 和磷酸化 mixed lineage kinase domain-like protein 的Ser358位点来触发坏死病。Resibufogenin 可通过诱导 reactive oxygen species (ROS) 积累发挥细胞毒性作用。Resibufogenin 可诱导凋亡和 caspase-3 和 caspase-8 活性。Resibufogenin 增加 Bax/Bcl-2 表达，并抑制 cyclin D1、cyclin E、PI3K、p-AKT、p-GSK3β 和 β-catenin 的蛋白表达。
S3245	Nodakenetin	Nodakenetin (NANI) 是从Angelica decursiva中分离出的植物性香豆素，可抑制 α-glucosidase、PTP1B、rat lens aldose reductase (RLAR)、AChE、BChE 和 β-site amyloid precursor protein cleaving enzyme 1 (BACE1)。Nodakenetin 可改变 Bax 和 Bcl-2 的蛋白质表达，并促进线粒体凋亡。Nodakenetin 具有抗肿瘤活性。
S3251	Goitrin	Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) 是板蓝根 Radix isatidis 的主要成分之一，广泛用于治疗发烧、清热的传统中药。Goitrin 具有抗病毒和抗内毒素活性。
S3262	Scopolin	Scopolin 是一种从 Arabidopsis thaliana (Arabidopsis) 中分离的香豆素，它通过激活 SIRT1 介导的信号级联反应来减轻肝脏脂肪变性，SIRT1介导的信号通路是脂质稳态的有效调节剂。
S3267	Kaempferol-3-O-rutinoside	Kaempferol-3-O-rutinoside (Nicotiflorin, Nikotoflorin, Kaempferol 3-O-β-rutinoside) 是从 Carthamus tinctorius 中提取的黄酮，可改变受伤神经元的形状和结构，减少凋亡细胞，下调 p-JAK2、p-STAT3、caspase-3 和 Bax 的表达，并降低Bax免疫反应性，并增加 Bcl-2 蛋白表达和免疫反应性。
S3271	Caudatin	Caudatin (Cauldatin)，一种来源于 Cynanchum auriculatum (C. auriculatum) 的C-21类固醇激素，可通过触发细胞周期阻滞和凋亡，在体外和体内均有效地抑制人神经胶质瘤的生长。
S3273	Hypericin	Hypericin (Hyp, HY) 是一种在 common St. John's Wort (Hypericum species) 中发现的天然物质，具有抗抑郁、抗肿瘤和抗病毒 (人类免疫缺陷病毒HIV和丙型肝炎病毒HCV) 活性。Hypericin 对 MAO (monoaminoxidase)、PKC (protein kinase C)、dopamine-beta-hydroxylase、reverse transcriptase、telomerase 和 CYP (cytochrome P450)。
S3291	Myristicin	Myristicin (Myristicine) 是一种在 Myristica fragrans 的种子 Nutmeg 中的萜烯样活性成分，是 monamine oxidase (MAO) 的弱抑制剂和 CYP1A2 的机理抑制剂。
S3296	Hispidulin	Hispidulin (Dinatin) 是一种在许多传统中草药中存在的天然活性成分，对癌蛋白激酶 Pim-1 具有抑制活性，其IC50值为2.71 μM。Hispidulin 通过 mitochondrial dysfunction 来诱导凋亡，并可抑制HepG2癌细胞中的 P13k/Akt 的信号通路。Hispidulin 通过激活 AMPK 信号通路发挥抗骨质疏松和骨吸收减弱的作用。
S3300	Desoxyrhaponticin	Desoxyrhaponticin (DC, DES) 是一种来自中国传统的营养食品 Rheum tanguticum Maxim. ex Balf. (rhubarb) 的对称二苯代乙烯配糖体，是 fatty acid synthase (FAS/FASN) 的抑制剂。Desoxyrhaponticin (DC, DES) 也是竞争性的 glucose 摄取的抑制剂，在兔肠膜囊泡和大鼠肠翻肠中的IC50值分别为148.3 μM和30.9 μM。Desoxyrhaponticin 对人癌细胞具有凋亡作用。
S3301	Cynarin	Cynarin (Cynarine) 是一种来自artichoke洋蓟的植物化学成分，具有多种药理特性，包括自由基清除、抗氧化剂、抗组氨酸和抗病毒活性。Cynarin 可阻断T细胞受体的 CD28 和抗原呈递细胞的 CD80 之间的相互作用。Cynarin 可触发 Nrf2 的核易位，恢复 glutathione (GSH) 和 reactive oxygen species (ROS) 的平衡，并抑制线粒体去极化。
S3305	Medicagenic acid	Medicagenic acid (Castanogenin) 是一种分离自 Herniaria glabra L. 的具有生物活性的三萜类五环糖苷，对 xanthine oxidase、collagenase、elastase 和 tyrosinase 具有低抑制活性。
S3240	Phaseoloidin	Phaseoloidin 是一种来自烟草毛状线虫的高纯酸糖苷，有助于植物抵抗鳞翅目草食动物。Phaseoloidin 具有抗补体 anti-complement 的作用。
S3242	Loureirin B	Loureirin B (LB, LrB)，是从Dracaena cochinchinensis中提取的类黄酮，是 PAI-1 的抑制剂，其IC50值为26.10 μM。Loureirin B 可下调TGF-β1刺激的成纤维细胞中的 p-ERK 和 p-JNK。Loureirin B 主要通过增加Pdx-1、MafA、细胞内ATP水平来促进胰岛素分泌，抑制 K_ATP 电流，Ca²⁺ 进入细胞内。
S3246	Picfeltarraenin IB	Picfeltarraenin IB 是从 Picriafel-terrae 中分离出的葫芦素糖苷，是 acetylcholinesterase (AChE) 的抑制剂。Picfeltarraenin IB 可用于治疗疱疹感染，癌症和炎症。
S3260	3'-hydroxy Puerarin	3'-hydroxy Puerarin 是从 Puerariae Lobatae Radix 中分离出的异黄酮。
S3264	Atractyloside potassium salt	Atractyloside potassium salt (ATR potassium salt) 是一种从 Xanthium sibiricum (Cang'erzi) 果实中分离出的毒性二萜糖苷，是一种有效的、特异性的 mitochondrial ADP/ATP carriers的抑制剂。Atractyloside potassium salt 可抑制大鼠心脏线粒体膜的 chloride channels。
S3269	Acetylcorynoline	Acetylcorynoline 是衍生自中草药 Corydalis bungeana 的主要生物碱成分，具有抗炎特性。Acetylcorynoline 可能通过降低 egl-1 的表达来抑制细胞凋亡通路，并增加 rpn5 的表达来增强 proteasomes 的活性。
S3270	Genipin 1-O-beta-D-gentiobioside	Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) 是从栀子 Gardenia jasminoides Ellis 中分离到的一种生物活性类环烷苷，具有保肝、抗炎、抗氧化和抗血栓形成的功能。
S3275	Senkyunolide I	Senkyunolide I (SEI, SENI) 是一种从 Ligusticum chuanxiong 中提取的口服活性化合物，具有止痛、抗偏头痛、神经保护、抗氧化和抗凋亡的活性。Senkyunolide I (SEI, SENI) 可上调 Erk1/2 的磷酸化，并诱导 Nrf2 的核易位，伴随着HO-1和NQO1的表达增强。Senkyunolide I (SEI, SENI) 可提高 Bcl-2/Bax 的比例，并抑制裂化的 caspase 3 和 caspase 9 的表达。
S3297	Hosenkoside A	Hosenkoside A 是从 impatiens balsamina 种子中分离出来的一种生物活性的葡糖苷。
S3303	Cyperotundone	Cyperotundone (CYT) 是在 Chuanxiong Rhizoma 和 Cyperi Rhizoma (CRCR) 中治疗偏头痛的有效成分。
S3307	Galangin 3-methyl ether	Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分，具有很强的抗细菌和抗真菌作用。
S3308	Caftaric acid	Caftaric acid (CA, Caffeoyl tartaric acid) 是一种具有抗氧化和抗炎作用的天然产物。
S3276	Hosenkoside K	Hosenkoside K 是从 impatiens balsamina 种子中分离出来的一种生物活性的葡糖苷。
S6906	Capric acid	Capric acid (DA, Decanoic acid, Decylic acid) 是在椰子油和棕榈油中天然存在的中链甘油三酯的成分，可通过直接抑制 AMPA receptor 来控制癫痫发作。癸酸还是 PPARs 的调节配体。由于其特殊的熔化范围，产品可能是固体、液体或半固体状态。
S6899	Licochalcone D	Licochalcone D (Lico D, LCD, LD) 是一种从中草药甘草 Glycyrrhiza inflata 中分离出的类黄酮，具有抗氧化、抗炎和抗癌的特性。Licochalcone D 可抑制LPS信号通路中NF-κB p65的磷酸化。Licochalcone D 可抑制 JAK2、EGFR 和 Met (c-Met) 活性，并诱导ROS依赖性的凋亡。Licochalcone D 还可诱导 caspases 的活化和 poly (ADP-ribose) polymerase (PARP) 的裂解。
S3265	9''-Methyl salvianolate B	9''-Methyl salvianolate B (9'-methyllithospermate B, 9'-Methyl lithospermate B, 9'''-Methyl salvianolate B) 是丹参 Radix Salviae Miltiorrhizae 的乙醇提取物中的活性成分。
S6885	Ailanthone	Ailanthone (AIL, Δ13-Dehydrochaparrinone) 是一种来自臭椿Ailanthus altissima的天然通过抗肝癌(HCC)成分，可通过降低 cyclins 和 CDKs 的表达、提高 p21 和 p27 的表达来诱导G0/G1期细胞周期阻滞。Ailanthone 可触发DNA损伤，其特征为 ATM/ATR 通路的激活。Ailanthone 可在Huh7细胞中诱导线粒体介导、涉及 PI3K/AKT 信号通路的细胞凋亡。Ailanthone 也是全长 Androgen Receptor (AR-FL)和组成型活性截断AR剪接变体(AR-Vs, AR_1-651)的抑制剂，对应的IC50值分别为69 nM和309 nM。
S0917	Allosecurinin	Allosecurinine (Phyllochrysine) 是一种从 M.indica 和 M.discoidea 分离的具有抗真菌活性的Securinega生物碱。
S0906	6-Methoxydihydroavicine	6-Methoxydihydroavicine (6-Methoxy Dihydrosanguinarine) 是一种从是博落回果实中分离得到的生物碱。
S3288	Absinthin	Absinthin (Absynthine) 是一种来自 Artemisia absinthium 的天然三萜内酯，具有抗炎特性。Absinthin (Absynthine) 可显著地增强 matrix metalloproteinase-8 (MMP-8) 的表达，并且是潜在的急性肺损伤(ALI)的候选治疗药物。
S3287	Rosamultin	Rosamultin 是一种从 Potentilla anserina L. 分离的19 α-hydroxyursane-type三萜，可抑制 HIV-1 protease。Rosamultin 对H₂O₂诱导的氧化损伤和细胞凋亡具有保护作用。
S6340	Guanidinoacetic acid	Guanidinoacetic acid (Guanidino acetic acid, GAA, Glycocyamine, Guanidinoacetate) 正在作为一种饮食制剂被研究。Guanidinoacetic acid 对体育锻炼的男性和女性均具有潜在的人体工程学益处。
S3220	Trigonelline	Trigonelline (Trigenolline) 是一种植物生物碱，是咖啡和葫芦巴的主要成分，具有抗脱粒、抗糖尿病、抗氧化、抗炎和神经保护的作用。 Trigonelline 可抑制FcεRI介导的细胞内信号通路，例如 PLCγ1、PI3K 和 Akt 的磷酸化。Trigonelline (Trigenolline) 还可抑制RBL-2H3细胞中 microtubule 的形成。
S3235	Sinapine	Sinapine 是一种从十字花科物种的种子中分离出来的生物碱，具有抗氧化、抗肿瘤和放射防护的作用。Sinapine 通过下调 P-glycoprotein 来抑制Caco-2细胞的增殖。
S3261	Myrislignan	Myrislignan 是一种分离自Myristica fragrans Houtt的木脂素并具有抗炎活性。Myrislignan 可抑制 interleukin-6 (IL-6) 和 tumour necrosis factor-α (TNF-α)。Myrislignan 剂量依赖性地抑制LPS刺激的巨噬细胞中 inducible NO synthase (iNOS) 和 cyclooxygenase-2 (COX-2) 的表达。Myrislignan 可抑制 NF-κB 信号通路的激活。
S3279	Polyphyllin B (Formosanin C)	Polyphyllin B (Formosanin C, FC) 是一种从Paris formosana分离得到的薯蓣皂苷，也是一种具有抗肿瘤活性的免疫调节剂。Polyphyllin B (Formosanin C, FC) 可诱导凋亡。
S3280	Linderene	Linderene (Lindenenol) 是从Lindera pulcherrima中分离出来的呋喃倍半萜类，具有抗菌和抗氧化活性。
S3281	Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside	Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside (Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobiosiden, Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) 是一种Descurainiae Semen的活性成分。
S3298	Caulophylline (N-Methylcytisine)	Caulophylline (N-Methylcytisine, Caulophyllin, NMC) 是一种具有抗炎活性的三环喹喔啉生物碱。Caulophylline 可与鱿鱼视神经节的 nicotinic acetylcholine receptors (nAChR) 结合，Kd值为50 nM。Caulophylline 可显著地降低 myeloperoxidase (MPO) 的活性，并通过抑制 IκB 和 IKK 磷酸化来阻断 NF-κB 的活化。
S3302	β,β-dimethyl-acryl-alkannin	β,β-dimethyl-acryl-alkannin (AN-I, β,β-Dimethylacrylalkannin) 是一种从 Arnebia nobilis Reichb.f. 的根中分离出来的萘醌，有潜力成为抗衰老成分。
S3304	Stylopine	Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) 可降低LPS刺激引起的 nitric oxide (NO)、prostaglandin E2 (PGE2)、tumor necrosis factor-alpha (TNF-alpha)、interleukin-1beta (IL-1beta) 和 IL-6 的生成，以及 cyclooxygenase-2 (COX-2) 的活性。Stylopine 是 Chelidonium majus L 的叶子的主要成分。
S3306	1,1,1,1-Kestohexaose	1,1,1,1-Kestohexaose 是crested wheatgrass叶中的主要DP 6果聚糖。
S3205	Perillaldehyde	Perillaldehyde (Perilladehyde, Perillal, PAE, PA) 是紫苏 Perilla frutescens（一种传统的抗氧化剂）的主要成分，可抑制BaP诱导的 AHR 的活化和 ROS 的产生，抑制 BaP/AHR 介导的 CCL2 chemokine 的释放，并激活 NRF2/HO1 抗氧化剂途径。
S3227	5,7-Dimethoxyflavone	5,7-Dimethoxyflavone (5,7-DMF) 是一种 cytochrome P450 (CYP) 3As 的抑制剂，可显著地降低肝脏中CYP3A11和CYP3A25的表达。5,7-Dimethoxyflavone (5,7-DMF) 也是一种有效的 Breast Cancer Resistance Protein (BCRP, ABCG2) 的抑制剂。5,7-Dimethoxyflavone (5,7-DMF) 是Kaempferia parviflora的主要成分之一，具有抗肥胖、抗炎和抗肿瘤作用。
S3237	Deoxyaconitine	3-Deoxyaconitine 是一种从 Aconitum Carmichaeli Debx 的根中分离出来的二萜类生物碱。
S3241	Loureirin A	Loureirin A 是一种黄酮类化合物，从被称为龙血的来源于Dracaena cochinchinensis的红色树脂中提取出来。Loureirin A 可通过破坏 PI3K/Akt 信号传导来抑制血小板platelet活化。Loureirin A 可抑制 Akt 磷酸化。
S3247	Icariside I	Icariside I (Icarisid I) 是 Epimedii Folium 的主要成分之一，可显着刺激细胞增殖和成骨细胞分化。
S3249	Corypalmine	Corypalmine ((R)-(+)-Corypalmine)，一种从 Stephania cepharantha 分离的生物碱，是 prolyl endopeptidase/oligopeptidase (PREP/POP) 的抑制剂，IC50值为128.0 μM。
S3255	Pectolinarigenin	Pectolinarigenin 是 Cirsium chanroenicum 中的一种抗炎活性成分，是 cyclooxygenase-2 (COX-2) 和 5-lipoxygenase (5-LOX) 的双效抑制剂。
S3256	Tectochrysin	Tectochrysin (Techtochrysin, NSC 80687) 是Alpinia oxyphylla Miquel的主要类黄酮之一。Tectochrysin 可显著地增加DR3、DR4 和 Fas的表达，并抑制 NF-κB 的活性。Tectochrysin 可诱导细胞凋亡。
S3257	Rebaudioside B	Rebaudioside B (Reb B) 是一种从甜叶菊 Stevia rebaudiana 分离的次要甜菊醇糖苷(SGs)之一，并且比许多主要SG具有更好的口感品质。
S3259	Rebaudioside D	Rebaudioside D (Reb D) 是在甜叶菊 Stevia rebaudiana (Bertoni) 的叶子中发现的几种糖苷(SGs)之一，这种糖已被鉴定为潜在的甜味剂。
S3272	Steviol (Hydroxydehydrostevic acid)	Steviol (Hydroxydehydrostevic acid, Hydroxy Dehydrostevic Acid, NSC 226902) 是甜味化合物甜菊糖的主要代谢产物，可抑制 CFTR 的活性，降低 AQP2 的表达并促进AQP2降解。
S3274	Glucosyl-vitexin	Glucosyl-vitexin (Glucosylvitexin) 是小米中主要的C-糖基黄酮，可抑制 thyroid peroxidase (TPO) 的活性。
S3282	Rebaudioside M	Rebaudioside M 是一种从甜叶菊Stevia rebaudiana Bertoni中分离的天然无热量潜在甜味剂，可应用于食品和饮料产品。
S3283	Marmesin	Marmesin (S-(+)-Marmesin, (+)-Marmesin, (S)-Marmesin) 是一种具有 COX-2 和 5-LOX 双重抑制作用的天然香豆素。
S3284	Tracheloside	Tracheloside 是一种从 Carthamus tinctorius 的种子中分离得到的木脂素糖苷，具有抗雌激素作用。Tracheloside 可显著地降低 alkaline phosphatase (AP)(一种雌激素诱导性标记酶) 的活性，IC50为 0.31 μg/ ml。Tracheloside 通过刺激 ERK1/2 来促进角质形成细胞的增殖。
S3285	Dihydrolycorine	Dihydrolycorine 是lycorine的衍生物，它是从 Lycoris radiata 草药中分离出来的生物碱。Dihydrolycorine 可阻断腹水细胞中的蛋白质合成并在体内稳定HeLa细胞多核糖体。Dihydrolycorine 具有降压和神经保护的作用。
S3299	Demethyleneberberine	Demethyleneberberine (DMB) 是黄柏Cortex Phellodendri Chinensis (CPC) 的成分，可显著地缓解体重减轻并降低 myeloperoxidase (MPO) 活性，同时显著地减少促炎细胞因子的生成，例如 interleukin (IL)-6 和 tumor necrosis factor-α (TNF-α)，并抑制 NF-κB 信号通路的激活。Demethyleneberberine (DMB) 可以通过激活 AMPK 途径改善NAFLD (非酒精性脂肪肝疾病)。
S0553	Butyl isobutyl phthalate	Butyl isobutyl phthalate (BIP) 是一种从 Laminaria japonica 的根状茎中分离出来的，α-glucosidase 的非竞争性抑制剂，其IC50值为38 μM。Butyl isobutyl phthalate 具有显著的降血糖作用和治疗糖尿病的潜力。
S3206	5a-Pregnane-3,20-dione	5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) 是一种内源性的孕酮代谢物。5a-Pregnane-3,20-dione 可使肌动蛋白actin解聚，并降低 actin 和 vinculin 的表达。5a-Pregnane-3,20-dione 可通过影响粘附和细胞骨架分子来参与促进乳腺瘤形成和转移。
S2440	Vindesine sulfate	Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, Desacetylvinblastine amide, DAVA, DVA, VDS) 是一种提取自 Catharanthus roseus的长春花生物碱，是一种有效的有丝分裂 mitosis 的抑制剂，并具有抗肿瘤的活性。Vindesine 与有丝分裂纺锤体的微管蛋白结合，可导致微管结晶和有丝分裂阻滞或细胞死亡。
S0949	Cucurbitacin IIb	Cucurbitacin IIb (CuIIb, Dihydrocucurbitacin F, 25-deacetyl hemslecin A) 可抑制 STAT3、JNK 和 Erk1/2 的磷酸化，而增强 IκB 和 NF-κB 的磷酸化，阻止 NF-κB 的核易位并降低 IκBα 和 TNF-α 的mRNA表达水平。Cucurbitacin IIb 是从Hemsleya amabilis 中分离出来的，具有抗炎活性并可诱导凋亡。
S6852	Gossypol	Gossypol (BL 193) 是一种从棉籽和根中分离出来的口服活性的多酚。Gossypol 是一种 5α-reductase 1 和 3α-hydroxysteroid dehydrogenase 的有效抑制剂，在无细胞试验中，对应的IC50值分别为3.33 μM和0.52 μM。Gossypol 还可抑制BH3肽与Bcl蛋白的结合，对 Bcl-XL 和 Bcl-2 的IC50值分别为0.4 μM和10 μM。Gossypol 在各种癌细胞中可诱导凋亡和细胞的生长抑制。
S3210	3'-Hydroxy-4'-methoxyacetophenone	3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) 是一种具有消炎潜能的活性多刺疟原虫提取物。
S3213	Veratryl alcohol	Veratryl alcohol (VA, Veratrole alcohol, 3,4-Dimethoxybenzyl alcohol) 是一种木质素降解真菌的次生代谢产物，是木质素过氧化物酶 Lignin peroxidase (LiP) 的天然底物。
S3214	Veratraldehyde (3,4-Dimethoxybenzaldehyde)	Veratraldehyde (3,4-dimethoxybenzaldehyde, VD, VAD, VAld, Verapamil Related Compound E, Methylvanillin) 是一种香兰素的衍生物，是从薄荷，生姜，波旁香草和树莓等水果中发现并分离出来的化学物质。Veratraldehyde 由于其令人愉悦的木质香气而被广泛用作调味剂和增香剂。Veratraldehyde 还可用作氧化还原循环剂。
S3215	2-O-α-D-Glucopyranosyl-L-ascorbic acid	2-O-α-D-Glucopyranosyl-l-ascorbic acid (AA-2G)，是抗坏血酸ascorbic acid (AA)的葡糖苷衍生物，在酶水解为抗坏血酸ascorbic acid后显示出维生素C的活性。AA-2G的抗肿瘤活性是由AA-2G快速水解释放的AA产生的ROS引起的。
S3203	D-Alanine	D-alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) 是一种 glycine site of the N-methyl-d-aspartate (NMDA) receptor 的内源性激动剂。
S3293	Gardenoside	Gardenoside 是一种从Gardenia栀子属果实中提取的天然化合物，具有保肝作用。Gardenoside 可抑制 TNF-α、IL-1β、IL-6 和 NFκB 的活化。Gardenoside 还对游离脂肪酸(FFA)诱导的细胞脂肪变性具有抑制作用。Gardenoside 可通过调节 P2X3 和 P2X7 受体来减轻慢性压迫性损伤大鼠的疼痛。
S3292	Falcarindiol	Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) 是一种天然的聚乙炔化合物，存在于伞形科的许多植物中。Falcarindiol 可抑制LPS刺激的 inducible nitric oxide synthase (iNOS)、tumor necrosis factor alpha (TNFα)、interleukin-6 (IL-6) 和 interleukin-1 beta (IL-1β) 的表达。Falcarindiol 可减弱LPS诱导的 JNK、ERK、STAT1 和 STAT3 信号分子的激活。
S3263	Agarotetrol	Agarotetrol 是一种在沉香树的水提取物中高浓度的酮衍生物。Agarotetrol 可通过加热产生LAC而有助于沉香木的香味。
S3216	Uridine 5'-diphosphoglucose disodium salt	Uridine-5'-diphosphoglucose (UDPG, UDP-Glc, UDP-D-Glucose, UDP-α-D-Glucose) 可激活神经免疫系统GPCR P2Y(14) receptor。Uridine-5'-diphosphoglucose 是动物组织和某些微生物中含葡萄糖的寡糖，多糖，糖蛋白和糖脂的前体。
S3250	Veratrine	Veratridine (Cevadine, Cevadin, Cevadene)是一种在百合科植物中发现的甾体生物碱，是 voltage-gated sodium channel 活化剂。Veratridine 会在大鼠中诱发类似焦虑的行为。
S7904	2',3'-cGAMP Sodium Salt	2',3'-cGAMP Sodium Salt (2'-3'-cyclic GMP-AMP Sodium)是响应哺乳动物细胞质中的DNA产生的，并能以高亲和力结合 STING，且有效地诱导 interferon-β (IFNβ)。2',3'-cGAMP 结合 STING 的Kd值为3.79 nM。
S6630	Dimethylcurcumin (ASC-J9)	Dimethylcurcumin (ASC-J9, Dimethyl curcumin, GO-Y025)是一种 androgen receptor (AR) 降解促进剂，可通过降解全长和剪接变异体的雄激素受体来抑制去势抵抗性前列腺癌的生长。
S2766	Glycerol	Glycerol (Glycerin)是一种透明，无色和粘稠的液体，可用作润肤剂，溶剂或甜味剂。Glycerol 可改变了聚丙烯酰胺核蛋白凝胶的分离特性。
S8587	Withaferin A	Withaferin A (WA, WFA)可通过对硫代烷基化敏感的氧化还原机制阻止肿瘤坏死因子诱导的IκB激酶β的激活，从而有效地抑制 NF-κB 激活。Withaferin A 可与中间丝状体蛋白(IF) vimentin 结合，并具有抗肿瘤和抗血管生成活性。Withaferin A 是一种从 Withania somnifera 分离的甾体内酯。
S2653	9-amino-CPT (9-Aminocamptothecin)	9-amino-CPT (9-Aminocamptothecin, 9-AC, Aminocamptothecin, 9-amino-20(S)-camptothecin)是一种 Topoisomerase I 抑制剂并具有有效的抗癌活性。9-amino-CPT (9-Aminocamptothecin) 是喜树碱的一种具有活性的、不溶于水的衍生物。
S8620	6-Diazo-5-oxo-L-norleucine	6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON)是一种从链霉菌中分离出来的抗生素，一种 glutaminase 的拮抗剂对cKGA（肾脏型谷氨酰胺酶）的IC50值约为1 mM。6-Diazo-5-oxo-L-norleucine 具有止痛，抗菌，抗病毒和抗癌的特性。
S2654	Neoruscogenin	Neoruscogenin 是从 R. rhizoma 中分离的天然皂苷元。Neoruscogenin 是一种有效且高亲和力的 RAR-related orphan receptor alpha (RORα or nuclear receptor NR1F1) 的激动剂。
S8970	HQNO	HQNO (2-heptyl-4-hydroxyquinoline-N-oxide)是一种由 P. aeruginosa 分泌的天然喹诺酮。HQNO 也是一种 electron transport chain 的有效抑制剂，其对呼吸链的泛醇-亚铁色素c氧化还原酶区段(Complex III)的Kd值为64 nM。在50 μM menadione存在下，HQNO 还是细菌和线粒体的 Type II NADH : quinone oxidoreductase (NDH-2) 的抑制剂，在50 μM menadione存在的条件下，其IC50值为7.3 μM。
S7895	Thapsigargin	Thapsigargin 是一种有效的、非竞争性的 the sarco/endoplasmic reticulum Ca²⁺ ATPase (SERCA) 的抑制剂，对carbachol诱导的[Ca2+]i瞬变在存不存在KCl预刺激条件下的IC50值分别为0.353 nM和0.448 nM。Thapsigargin 可诱导细胞凋亡。Thapsigargin 提取自植物Thapsia garganica。
S7905	3',3'-cGAMP	3',3'-cGAMP (3',3'-cyclic GMP-AMP, Cyclic GMP-AMP, cGAMP)可激活内质网(ER)内源性受体 stimulator of interferon genes (STING) ，从而诱导抗病毒状态和I型IFN的分泌。
S7821	Bufalin	Bufalin (BF)是类固醇受体共激活剂 SRC-3、SRC-1 和 Na+/K+-ATPase 的有效抑制剂。Bufalin 可与Na+/K+-ATPase的亚基α1、α2和α3结合，其Kd值分别为42.5 nM、45 nM和40 nM。Bufalin 是一种从中药蟾酥中分离出来的，具有抗癌活性的，类地高辛免疫反应的主要成分。
S7862	Rottlerin	Rottlerin (Mallotoxin, NSC 56346, NSC 94525)是一种从 Mallotus Philippinensis 纯化出来的天然化合物，一种特效的 Protein kinase 的抑制剂，对PKCδ(来自杆状病毒感染的Sf9昆虫细胞)、PKCδ(来自猪脾)和CaM kinase III的IC50值分别为3 μM、6 μM和5.3 μM。Rottlerin 还可以抑制PKCα、PKCγ、PKCβ、PKCη、CKII和PKA，其IC50值分别为30 μM、40 μM、42 μM、82 μM、30 μM和78 μM。
S2447	Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222)	Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) 是一种有效的微管蛋白聚合抑制剂，IC50为3.4 μM。
S6790	Ellipticine hydrochloride	Ellipticine Hydrochloride (NSC 71795, PZE)是一种有效的 DNA topoisomerase II 的抑制剂，并通过其与 cytochromes P450 (CYP) 和 peroxidases 的氧化作用介导形成共价DNA加合物。Ellipticine Hydrochloride 是从澳大利亚的夹竹桃科常绿乔木中分离出来的具有抗肿瘤活性的天然产物。
S8964	Actinomycin D (Dactinomycin)	Actinomycin D (Dactinomycin, Act D, RASP-101)是一种从链霉菌属的土壤细菌中分离出来的重要的多肽抗生素。Actinomycin D (Dactinomycin) 可抑制 DNA repair，并使 cell cycle 停滞在G1期，其IC50值分别为0.42 μM和0.4 nM。Actinomycin D (Dactinomycin) 是 autophagy 的激活剂，可在高危慢性淋巴细胞性白血病中诱导p53依赖性细胞的死亡并延长生存期。
S2288	Rubitecan	Rubitecan (9-NC, 9-Nitro-camptothecin, Partaject Orathecin, Partaject rubitecan, RFS 2000) 是一种拓扑异构酶I topoisomerase I 的抑制剂，从中国喜树的树皮和叶子中提取。Rubitecan 也是一种具有抗肿瘤活性的口服喜树碱。
S2009	Indirubin-3'-monoxime	Indirubin-3'-monoxime (Indirubin-3'-oxime)是一种选择性的CDK抑制剂，对CDK1-cyclinB, CDK2-cyclinA, CDK2-cyclinE, CDK4-cyclinD1, CDK5-p35的IC50分别为 0.18 μM, 0.44 μM, 0.25 μM, 3.33 μM, 0.065 μM。Indirubin-3'-monoxime是一种直接、选择性的5-lipoxygenase抑制剂，IC50为7.8-10 µM。
S1031	3-Hydroxybutyric acid	3-Hydroxybutyric acid (3-hydroxybutanoic acid, β-Hydroxybutyric acid, BHB)是一种在I型糖尿病中升高的小分子代谢产物。
S2342	Phloretin (RJC 02792)	Phloretin (RJC 02792, NSC 407292, Dihydronaringenin)是一种二氢查尔酮，含有多元酚。
S9440	Naringenin chalcone	Naringenin chalcone (Chalconaringenin, Isosalipurpol, trans-2'4'6'4-tetrahydroxychalcone) is the main active component of tomato skin extract, has been proposed as an antioxidant, an anti-inflammatory, and a regulator of fat and sex hormone metabolism.
S2325	Morin Hydrate	Morin hydrate (Aurantica) 是一种化学化合物，用来检测溶液中的铝或锡的存在，因为Morin hydrate与铝或锡可以形成特有的荧光配位络合物。
S6670	GPNA (L-γ-Glutamyl-p-nitroanilide)	GPNA (L-γ-Glutamyl-p-nitroanilide)是一种有效的谷氨酰胺 (Gln) 转运蛋白ASCT2(SLC1A5) 的选择性抑制剂，Ki为55 µM。
S2210	Sphingosine	鞘氨醇，Sphingosine (2-amino-4-trans-octadecene-1,3-diol, C18 Sphingosine)，是具有不饱和烃链的18个碳原子的氨基醇，它形成鞘脂的主要部分，鞘脂是一类细胞膜脂质，其中包括鞘磷脂，一种重要的磷脂。
S6674	Cytosporone B	Cytosporone B是天然存在的核孤儿受体Nur77(NR4A1) 激动剂，EC50为0.278 nM。
S6474	3,5-diiodo-L-thyronine (3,5-T2)	3,5-diiodo-L-thyronine (3,5-T2, NSC 90469)是甲状腺激素的内源性代谢产物。 3,5-Diiodo-l-thyronine是治疗肥胖和肝脏脂肪变性的潜在降血脂药。
S9218	Phytolaccagenin	Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phtolaccae.
S6653	Nigericin (NSC 292567) sodium salt	Nigericin (NSC 292567) sodium salt是从Streptomyces hygroscopicus衍生的抗生素，通过充当H⁺，K⁺和Pb²⁺的离子载体起作用。Nigericin可以激活NLRP3炎性体以诱导促炎和免疫刺激过程。
S3911	Veratramine	Veratramine (NSC 17821, NSC 23880), a major alkaloid from Veratrum nigrum L., has distinct anti-tumor and anti-hypertension effects. It is a good membrane permeant, undergoes rapid passive diffusion, and has a good stability in the gastrointestinal tract during its absorption.
S9403	Ecliptasaponin A	Ecliptasaponin A, a natural triterpenoid glucoside, has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-mesenchymal transition.
S3928	Baccatin Ⅲ	Baccatin Ⅲ is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It exhibits immunomodulatory and anticancer chemotherapeutic activities.
S4938	Cedrol	Cedrol是一种天然存在的倍半萜烯醇，是有效的、竞争性的抑制剂，抑制CYP2B6介导的安非他酮羟化酶(bupropion hydroxylase)，Ki值为0.9 μM。它还能抑制CYP3A4介导的咪达唑仑羟基化，Ki为3.4 μM。对CYP2C8, CYP2C9和CYP2C19的活性仅有微弱的抑制作用。
S3942	Cardamonin	Cardamonin (Alpinetin chalcone)天然存在于良姜属物种的果实中，具有抗炎和抗肿瘤活性。它是一种新型的hTRPA1离子通道拮抗剂，IC50为454 nM，而不与TRPV1和TRPV4相互作用。
S3756	Methyl salicylate	Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.
S3763	Cinnamaldehyde	Cinnamaldehyde is a flavonoid that is naturally synthesized by the shikimate pathway. Its supplementation can improve glucose and lipid homeostasis in diabetic animals; a TRPA1 agonist.
S3605	Borneol	Borneol是一种分离自药用植物如艾纳香、芳味冰片香木的双环类单萜化合物。它是TRPM8的激动剂，能够增加眼部表面湿润。
S4787	Methyl syringate	Methyl syringate (Syringic Acid Methyl Ester), a plant phenolic compound, is a specific and selective TRPA1 agonist.
S3867	(E)-Cardamonin	(E)-Cardamonin (Alpinetin chalcone, cardamomin) is a naturally occurring chalcone with strong anti-inflammatory activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor.
S4714	(-)-Menthol	(-)-Menthol (L-Menthol, Levomenthol, Menthomenthol, Menthacamphor) 是薄荷醇的左旋异构体，常被用作冷却剂，可激活TRPM8。
S2332	Neohesperidin	Neohesperidin (NSC 31048) 是一种抗氧化剂，在1,1-diphenyl-2-picryldydrazyl（DPPH）自由基清除测定中，IC50为22.31 μg/ml。
S5755	Methyl Eugenol	Methyl eugenol (4-allylveratrole, eugenyl methyl ether, O-methyleugenol), as a constituent in leaves, fruits, stems, and/or roots, is used as a flavoring agent, as a fragrance and as an anesthetic in rodents.
S2935	Nicotinamide Riboside Chloride	Nicotinamide Riboside Chloride是烟酰胺核糖(NR)的氯化物盐形式。NR是维生素B3的衍生物，可作为作为NAD或NAD⁺的前体。
S3607	Sarsasapogenin	Sarsasapogenin (SAR, Parigenin)是一种甾体皂甙元，能够诱发ROS的产生并激活unfolded protein response (UPR)信号通路。SAR能够有效地抑制NF-κB和MAPK的激活，在LPS刺激的巨噬细胞中抑制IRAK1、TAK1和IκBα的磷酸化。
S2425	Apocynin (NSC 2146)	Apocynin (NSC 2146, Acetovanillone, NSC 209524)是一种选择性NADPH氧化酶抑制剂，IC50 为10 μM.
S9332	(+)-Dipentene	(+)-Dipentene, occurring commonly in nature as the fragrance of oranges, is a flavoring agent in food manufacturing.
S5578	Cadaverine	Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue.
S5140	Cinene	Cinene (Limonene, Dipentene) is a clear, colorless liquid hydrocarbon classified as a cyclic monoterpene, and is the major component in oil of citrus fruit peels. It is usually used to make fragrances and flavors.
S5408	Isoprene	Isoprene, also called 2-methyl-1,3-butadiene, is usually used as a chemical raw materia.
S6206	1-Butanol	1-Butanol是糖类和其他碳水化合物发酵的次要产物，存在于许多食物和饮料中。
S6019	2-Phenylphenol	2-Phenylphenol，在柠檬中发现，是一种抗真菌剂和防腐剂，用于食品调味剂中。
S5429	Diallyl sulfide	Diallyl sulfide, a thioether found naturally in garlic, is a selective inhibitor and also a substrate of CYP2E1 with an IC50 of 17.3 μM. It has protective effects against alcohol- and acetaminophen-induced hepatotoxicity in many studies.
S6751	Brevianamide F	Brevianamide F, belonging to a class of naturally occurring 2,5-diketopiperazines, is the simplest member and the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketopiperazines that are produced by the fungi A.fumigates and Aspergillus sp..
S6359	Purine	Purine是一种杂环芳香有机化合物，在DNA和RNA中均发挥关键作用。它还是很多生物分子，如ATP、GTP、cAMP、NADH和辅酶A的重要组成成分。
S2353	Sapogenins Glycosides	Sapogenins glycosides (Saponins)是糖苷配基或非糖类，属于天然产品Saponins部分家族。
S3627	Tryptamine	Tryptamine是一种单胺生物碱，可能作为神经调节剂和神经递质发挥作用。它是hTAAR1的激动剂，还是非选择性的serotonin receptor激动剂和羟色胺-去甲肾上腺素-多巴胺释放剂(SNDRA)。
S5153	Tetrahydroberberine	Tetrahydroberberine (Canadine) is an isoquinoline alkaloid with micromolar affinity for dopamine D2 (antagonist, pKi = 6.08) and 5-HT1A (agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.
S3823	Schizandrol A	Schizandrol A is one of the effective components in the dried fruit of Schizandra chinensis Bail and works by increasing dopamine, a neurotransmitter, in the brain.
S5642	Homovanillic acid	Homovanillic acid (Vanillacetic acid) is a major catecholamine metabolite that is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain.
S9087	Tenuifolin	Tenuifolin, a secondary saponin isolated from hydrolysates of polygalasaponins, inhibits beta-amyloid synthesis in vitro and has nootropic activity in vivo via acetylcholine esterase inhibition and increases norepinephrine and dopamine production.
S2367	Tetrahydropapaverine HCl	Tetrahydropapaverine (Norlaudanosine) 是TIQs的一种，是Salsolinol 和 Tetrahydropapaveroline的类似物，对多巴胺神经元具有神经毒性作用。
S3937	Pterostilbene	Pterostilbene is a natural dietary compound and the primary antioxidant component of blueberries. It has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes.
S6428	Wilforlide A	Wilforlide A是雷公藤多甙中的活性化合物，是用于治疗自身免疫疾病的传统中药。
S5850	Vasicine	Vasicine，可分离自A. vasica，是一种生物碱。它是天然的cholinesterase（胆碱酯酶）抑制剂，在临床前模型中具有抗胆碱酯酶活性，可用于阿尔茨海默病的治疗药物开发。
S7956	Brusatol	Brusatol (NSC 172924)，可分离自B. javanica果实，是一种NRF2抑制剂。
S3781	Ginkgolide C	Ginkgolide C (BN-52022), isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease. It is an activator of MMP-9.
S9513	Senkyunolide A	Senkyunolide A is one of the major bioactive ingredients in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments.
S6049	(+)-(S)-Carvone	(+)-(S)-Carvone是一种主要存在于香菜和莳萝种子油中的单萜，用于化妆品、食品和药品制备中。
S6700	Castor oil	Castor oil is a popular natural treatment for various common conditions and often used in natural beauty products.
S3830	Protodioscin	Protodioscin (Furostanol I), a steroidal saponin compound found in a number of plant species, is able to stimulate testosterone production and it also has an androgen-mimetic action, binding and activating the testosterone receptors.
S8870	Epibrassinolide	Epibrassinolide是一种可从多种植物中分离而来的油菜素类固醇，减少毒性，在植物应激反应下刺激其健康生长。
S6701	Corn Oil	Corn oil 是一种精制的植物油，常用于脂溶性物质的载体。
S9326	Scopolamine	Scopolamine (Skopolamin) is a tropane alkaloid derived from plants of the nightshade family, specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties.
S3860	Allicin	Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S6493	n-Butylidenephthalide	n-Butylidenephthalide ((Z)-Butylidenephthalide, 3-Butylidenephthalide, Butylidenephthalide) 可从当归的氯仿提取物中分离出来，它具有多种生物活性，如减少心绞痛、血小板聚集、增殖、非特异性痉挛。
S6601	(±)-Equol	(±)-Equol是大豆异黄酮、黄豆苷和黄豆苷元的一种代谢物。
S3687	Urea	Urea (Carbonyldiamide, Ureophil) 是一种溶解度高的有机化合物，源自肝脏中由氨基酸脱氨基作用形成的氨。它是蛋白质分解代谢中的主要最终产物。
S3839	1-Deoxynojirimycin	1-Deoxynojirimycin (duvoglustat, moranolin) is a potent α-glucosidase inhibitor and most commonly found in mulberry leaves. It has therapeutic potency against diabetes mellitus.
S3190	N6-methyladenosine (m6A)	N6-methyladenosine (m6A, NSC-29409, 6-Methyladenosine, N-Methyladenosine) 是碱基修饰的腺苷类似物，在天然RNAs中作为稀有核苷。N6-methyladenosine(m6A)是mRNA的第五种碱基。
S2370	Ursolic Acid	Ursolic acid (NSC 167406, NSC-4060, Prunol, Urson, Malol)是一种五环三萜酸，在化妆品中使用。
S6426	Hesperidin methylchalcone	Hesperidin methylchalcone源于柑橘，具有强效的抗氧化活性。
S3821	Nuciferine	Nuciferine (Sanjoinine E, (-)-Nuciferine, VLT 049) is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn and possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities.
S9227	Sinensetin	Sinensetin (Pedalitin Permethyl ether), a natural polymethoxylated flavone, has potent antiangiogenesis activity.
S3973	L-SelenoMethionine	L-SelenoMethionine (SeMet), a naturally occurring amino acid, is a major food-form of selenium. It has been used as a supplement, and exhibits some important functions like cancer prevention and antioxidative defense.
S2324	Sodium Monensin (NSC 343257)	Sodium Monensin (NSC 343257)从 Streptomyces cinnamonensis中分离的, 是一种众所周知的天然的聚醚类离子载体抗生素的代表。
S2348	Rotenone (Barbasco)	Rotenone (Barbasco, Dactinol, Paraderil, Rotenon, Rotocide) 是一种植物杀虫剂，是线粒体电子传递mitochondrial electron transport的抑制剂。Rotenone 可抑制 NADH/DB oxidoreductase 和 NADH oxidase，对应的IC50值分别为28.8 nM和5.1 nM。Rotenone 可通过增强线粒体活性氧的产生来诱导凋亡。
S2265	Artesunate (WR-256283)	Artesunate (WR-256283) 是一种抗疟类药，作用于小细胞肺癌细胞系H69，IC50为< 5 μM。它是一种潜在的STAT3抑制剂，在体外对癌细胞有选择性细胞毒性作用；是有效的EXP1抑制剂。
S6176	Scyllo-Inositol	Scyllo-Inositol (Scyllitol, Cocositol, Quercinitol, AZD 103, Scyllo-Cyclohexanehexol)是一种天然存在的植物糖醇，在椰树中含量最为丰富。
S6292	(S)-2-Hydroxysuccinic acid	(S)-2-Hydroxysuccinic acid (L-Malic acid)是天然存在的苹果酸同分异构体，主要于酸性和未成熟的水果中被发现。
S6346	L-(+)-Arabinose	L-(+)-Arabinose (DL-Arabinose, Pectinose) 是一种用于鉴定、区分戊糖异构酶的底物。
S6061	DL-m-Tyrosine	DL-m-Tyrosine是一种有效的、广谱的植物毒素，从某些细叶羊茅的根部流出。
S6163	Traumatic acid	Traumatic acid (Trans-2-dodecenedioic acid)是一种植物激素，首次于损伤的绿豆中分离。它是一种有效的伤口愈合剂，是前列腺素合成的中间物。
S6264	Rutin hydrate	Rutin (Quercetin-3-O-rutinoside, Rutoside, Sophorin) 是在多种植物如柑橘中所发现的一种配糖。
S6112	Oxalacetic acid	Oxalacetic acid (Oxaloacetic acid, 2-Oxosuccinic acid, Ketosuccinic acid)是三羧酸循环的中间物，它与乙酰辅酶A经柠檬酸合酶催化反应生成柠檬酸盐。它还参与糖原异生、尿素循环、乙醛酸循环、氨基酸合成和脂肪酸合成等过程。Oxaloacetate是Complex II的抑制剂。
S6221	Methyl cinnamate	Methyl cinnamate 是花椒(Zanthoxylum armatum)的活性成分，是一种广泛使用的具有抗菌和 tyrosinase 抑制剂活性的天然香料化合物。Methyl cinnamate 通过激活3T3-L1前脂肪细胞中的 CaMKK2--AMPK 信号通路来抑制脂肪细胞分化。
S6008	p-Hydroxybenzaldehyde	p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol)，存在于兰花Gastrodia elata、Galeola faberi和香草中，是一种羟基苯甲醛，可与NAD+和H20反应生成4-hydroxybenzoate、NADH和两质子。
S6011	Acetamide	Acetamide (ethanamide, Acetic acid amide) 是一种有机化合物，可被用作塑化剂和工业溶剂。
S6018	2,3,4-Trihydroxybenzoic acid	2,3,4-Trihydroxybenzoic acid是转筋草中的酚组分，具有抗氧化活性。
S6043	3-Indoleacetonitrile	3-Indoleacetonitrile是一种植物生长激素，是光照诱导的生长素抑制性激素。
S6045	L-Arabinitol	L-Arabinitol (L-lyxitol)是一种糖醇，存在于所有生物中。在很多食物如甘薯、鹿果、乌头叶菜豆和欧洲栗中都有发现。
S6047	Lactose	Lactose是一种天然存在于奶及乳制品中的二糖。
S6071	3,5-Dimethoxyphenol	3,5-Dimethoxyphenol (Phloroglucinol dimethyl ether)是一种发现于红豆杉叶中的毒素代谢物。
S6076	Phenylacetylglutamine	Phenylacetylglutamine is a product formed by the conjugation of phenylacetate and glutamine. It is a normal constituent of human urine, but other mammals such as the dog, cat, rat, monkey, sheep, and horse do not excrete this compound.
S9564	p-Hydroxy-cinnamic Acid	p-Hydroxy-cinnamic Acid在体外具有抗疟活性和体内抗骨质疏松活性。
S2254	4-Demethylepipodophyllotoxin(NSC-122819,VM-26)	4-Demethylepipodophyllotoxin (NSC-122819, VM-26, DMEP) is an antimitotic agent which binds to monomeric tubulin, preventing micro-tubule polymerization. It is a potent inhibitor of microtubule assembly.
S2442	Inosine	Inosine (NSC 20262, INO 495) 是一种核苷，由次黄嘌呤通过β-N9-糖苷键结合到核糖环上形成。
S2280	Chlorogenic Acid	Chlorogenic acid (NSC 407296, Heriguard) 是一种羟基肉桂酸，是天然存在的有机化合物。
S6250	L-Lactic acid	L-Lactic acid是一种天然产物，可被用作食物添加剂。
S6275	(−)-β-Pinene	(−)-β-Pinene (Nopinene)是存在于很多植物中的天然有机化合物。它对滨藜第三龄幼虫具有致死性（LD50 = 65 μg/larva）、抑制感染性支气管炎病毒的肤质（IC50 = 1.32 mM），在Vero细胞中毒性浓度CC50大于10 mM。
S6287	3-Methylbutanoic acid	3-Methylbutanoic acid (Isovaleric acid, Delphinic acid, 3-Methylbutyric acid, Isopentanoic acid, β-methylbutyric acid)是一种天然脂肪酸，广泛存在于多种植物和精油中。
S6296	Octanoic acid	Octanoic acid (caprylic acid)天然存在于多种哺乳动物的乳汁（奶）中，是椰子油和棕榈仁油中的微量组分。它被用于生产香水酯类，也用于制作染料。
S6303	trans-2-Hexenal	Trans-2-hexenal (Leaf aldehyde)是α,β不饱和羰基化合物，可保护植物免受有害物质侵染。
S5887	Khellin	Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin)分离自阿密茴（伞形科）种子，被用于治疗多种疾病。
S2331	Neohesperidin Dihydrochalcone (Nhdc)	Neohesperidin dihydrochalcone(Nhdc, NCI-c60764) 是源于柑橘类的一种人造甜味剂。
S9432	Ginkgolic Acid	Ginkgolic acid, toxic phenolic compounds present in the fruits and leaves of Ginkgo biloba L., is a potent sumoylation inhibitor also reported to inhibit histone acetylation transferase (HAT).
S9445	Ginkgolic Acid (C13:0)	Ginkgolic Acid (C13:0) 是银杏中的一种天然抗龋剂，对变形链球菌(S. mutans)具有抗菌活性，并能抑制与其致龋性相关的特定毒力因子。银杏酸是一种有效的 sumoylation 抑制剂，据报道可抑制 histone acetylation transferase (HAT) 。
S2360	Solanesol (Nonaisoprenol)	Solanesol (Nonaisoprenol, Betulanonaprenol) is a long-chain polyisoprenoid alcohol compound with inhibitory activities toward FAK. It mainly accumulates in solanaceous crops, including tobacco, tomato, potato, eggplant, and pepper plants.
S2369	Troxerutin	Troxerutin 是一种黄酮醇类，是一种黄酮类化合物。
S5934	(-)-Fenchone	Fenchone是苦艾酒中的组分，是茴香中的香精油。在食物和香水中，它被用做调料（香料）。
S6055	(S)-(−)-Limonene	(S)-(−)-Limonene是一种发现于橘皮油中的香料单萜，天然存在于草本精油、茶树油和松节油中。
S6058	β-Caryophyllene	β-Caryophyllene是一种天然存在的双环倍半萜烯，是很多精油的组分之一。它是非类固醇的抗炎药物、香料和代谢物。
S6059	cis-3-Hexen-1-ol	cis-3-Hexen-1-ol (Leaf alcohol)是一种重要的芳香族化合物，用于果蔬香精和香水中，也是捕食性昆虫的引诱剂。
S6118	Terpinen-4-ol	Terpinen-4-ol是一种天然存在的单萜，是茶树油的主要活性成分，具有多种生物活性如抗真菌活性。
S6150	Farnesyl Acetate (mixture of isomers)	Farnesyl Acetate是一种香料化合物，可在一些食物如蓝莓中发现。
S6162	2-Octenoic acid	2-Octenoic acid (2-Octenoate)是一种正常的有机酸，由脂族醛通过肝脏微粒体氧化产生。它是天然存在于尿液和血浆中的代谢物。
S6164	(-)-Citronellal	(-)-Citronellal是香茅油的组分，用于活性化合物的合成。
S6185	Arachidonic acid	Arachidonic acid (Arachidonate)是非饱和必需脂肪酸，在动物和人类肝脏、脑部和腺器官脂肪中都有发现。它是前列腺素、凝血噁烷和白细胞三烯的生物合成的前体化合物。
S6208	Diethyl malonate	Diethyl malonate天然存在于葡萄和草莓中，用于合成其他化合物。
S9476	Dendrobine	Dendrobine是一种分离自石斛的植物碱，用于对石斛兰Dendrobium的质量控制和鉴别。
S9551	Uvaol	Uvaol是一种从橄榄渣油的非甘油酯组分发现的五环三萜，具有促炎-抗炎活性。
S4792	N-Acetylneuraminic acid	N-Acetylneuraminic acid (Neu5Ac, NeuAc, Acido aceneuramico, Acide aceneuramique, Acidium aceneuramicum, Sialic acid, NANA) is the predominant sialic acid found in mammalian cells. Sialic acids are negatively charged monosaccharides attached to the end of sugar chains, giving rise to a wide variety of glycoproteins and glycolipids in biological fluids and cell membranes.
S5526	β-Alanine	β-Alanine (beta-Alanine, 3-Aminopropanoic acid) is a naturally occurring beta amino acid formed in vivo by the degradation of dihydrouracil and carnosine. It acts as a neurotransmitter by activating glycine and GABA receptors.
S4676	Gluconolactone	Gluconolactone是一种天然存在的聚羟基酸，具有螯合金属离子、保湿、抗氧化活性。
S5851	4'-Methoxychalcone	4'-Methoxychalcone存在于柑橘属植物中，是一种查耳酮衍生物，具有多种药理活性，如抗肿瘤和消炎活性。
S9481	Blinin	Blinin可从Conyza blinii中分离，在中国的西南地区被用作民间药物。
S9557	Isobergapten	Isobergapten是一种香豆素，具有调节植物生长活性。
S9560	Anisodamine Hydrobromide	Anisodamine (6-Hydroxyhyoscyamine)是天然存在的阿托品（atropine）衍生物，具有消炎活性。它能抑制α1-adrenergic receptors和mAChRs。
S5865	Hyaluronic acid	Hyaluronic acid (HA, Hyaluronan, Hyaluronate)(透明质酸)是一种带阴离子的、非硫酸化的粘多糖，在结缔组织、上皮和神经组织中广泛分布。它常用于皮肤护理。
S9193	Aristolochic acid A	Aristolochic acid A (Aristolochic Acid I, Aristolochin, Aristolochine, TR 1736)是一种致癌、致突变和具有肾毒性的试剂，来源于马兜铃科的开花植物。Aristolochic acid A 可显著降低 activator protein 1 (AP-1) 和 nuclear factor-κB (NF-κB) 的活性。
S9563	Evodine	Evodine是一种天然产物（源于吴茱萸），在中国药典中被记载作为吴茱萸质量评估的生物标志物。Evodine 也是一种有效的 P-gp 的抑制剂。
S9554	Bakkenolide A	Bakkenolide A (Fukinanolid)分离自毛裂蜂斗菜，具有抗癌活性，可对炎性细胞因子的形成发挥保护作用。
S9552	Farrerol	Farrerol是杜鹃花中一种重要的活性成分，具有抗氧化和消炎活性。
S9487	Praeruptorin C	Praeruptorin C是源于白花前胡干燥根的天然产物，具有抑制破骨细胞形成和吸收的作用。它常常在中药中被用于治疗上呼吸道感染，是解热、镇咳和促黏液溶解的试剂。
S9484	Darutoside	Darutoside源于植物提取物，通过减少炎症反应和修复胶原发挥有效的再生活性。
S9480	Raspberry Ketone	Raspberry ketone (p-Hydroxybenzyl acetone, Frambinone, Oxyphenylon, Rheosmin, Rasketone)是一种天然存在的酚类化合物，是红莓中的主要芳香化合物。
S9473	Nuzhenide	Nuzhenide (Specnuezhenide)是橄榄仁中的重要成分，属于糖脂类。
S9474	Acetylharpagide	Acetylharpagide是来源于金疮小草（Ajuga decumbens）的一种单体化合物，广泛用于治疗传染性和炎症性疾病。
S5846	Apocarotenal	Apocarotenal是一种类胡萝卜素，可存在于菠菜和柑橘类水果中，是维他命A的前体。
S9475	Hupehenine	Hupehenine是来源于湖北贝母鳞茎的甾体生物碱，具有抑制乙酰胆碱、拮抗毒蕈碱性受体、抑制胆碱酯酶的潜力。
S9479	Complanatoside A	Complanatoside A是分离自沙苑子（Astragalus complanatus）中的一种黄酮苷，可被用作沙苑子的质量控制指标。
S9488	Praeruptorin D	Praeruptorin D是前胡中的成分，具有抗肿瘤和消炎活性。
S9491	(+)-Guaiacin	(+)-Guaiacin存在于草药和香料中，属于木脂素类。
S9555	Vincristine	Vincristine (Leurocristine, NSC-67574, 22-Oxovincaleukoblastine) 是长春花中的生物碱，具有抗肿瘤活性。Vincristine 可抑制有丝分裂纺锤体中的微管 microtubule 形成，其结合微管的Ki值为85 nM。
S9562	Pomolic acid	Pomolic acid是一种分离自野鸦椿（Euscaphis japonica）的五环三萜，可有效地抑制细胞生长和诱导凋亡。
S9192	Vitexin	Vitexin (Apigenin-8-C-glucoside), an naturally occuring apigenin flavone glycoside, acts as a platelet aggregation and alpha-glucosidase inhibitor and shows antineoplastic activity.
S3964	Mucic Acid	Mucic Acid (Schleimsaure, Saccharolactic acid, Tetrahydroxyadipic acid, D-Glucaric acid, Galactaric acid) is the dicarboxylic sugar acid resulting from oxidation glactose with dilute nitric acid. It is a substrate of galactarate O-hydroxycinnamoyltransferase.
S5928	Zerumbone	Zerumbone，分离自姜科植物，是一种天然存在的膳食化合物，具有多种生化活性，如抗增殖、抗氧化、消炎和抗癌活性。
S5794	Glycochenodeoxycholic acid	Glycochenodeoxycholic acid (Glycochenodeoxycholate, Chenodeoxycholylglycine, Glycine chenodeoxycholate)是由鹅去氧胆酸盐和甘氨酸在肝脏中形成的胆汁盐。它是一种去垢剂，能溶解脂肪，促进吸收。
S5820	L-Hydroxyproline	L-Hydroxyproline (trans-4-Hydroxy-L-proline)是一种胶原特异的氨基酸。它被用作骨转换和肝纤维化的诊断标记物。
S5824	Cinnamyl alcohol	Cinnamyl alcohol是一种存在于肉桂中的天然产物。
S5821	Linoleic acid	Linoleic acid (9,12-octadecadienoic acid)是一种必需脂肪酸，用于合成花生四烯酸，存在于细胞膜脂质中。
S5823	L-Pyroglutamic acid	L-pyroglutamic acid (L-pyroglutamate, 5-Oxoproline, pidolic acid)是一种天然营养物，是来源于谷氨酸的氨基酸。它是谷胱甘肽循环的代谢物，能通过5-羟脯氨酸酶转化为谷氨酸。
S5828	L-Abrine	L-Abrine (N-Methyl-L-tryptophan)是相思子根部的毒性清蛋白，可抑制核糖体。
S9367	Adenosine disodium triphosphate	Adenosine disodium triphosphate (ATP disodium) is the sodium salt form of adenosine triphosphate (ATP), a complex organic chemical that provides energy to drive many processes in living cells.
S5805	Allopregnanolone	Allopregnanolone是一种神经类固醇，在脑内由黄体酮合成而来，是高效的GABAA receptor正向别构调节剂。
S5771	Sulforaphane	Sulforaphane 是一种天然存在的异硫氰酸盐，存在于十字花科蔬菜如西兰花、卷心菜、羽衣甘蓝。它是 Nrf2 的诱导物。Sulforaphane 也是 histone deacetylase (HDAC) 和 NF-κB 的抑制剂。Sulforaphane 可增加 heme oxygenase-1 (HO-1)，并降低 reactive oxygen species (ROS) 的水平。Sulforaphane 诱导细胞周期停滞和凋亡。
S9334	2-Pentylfuran	2-Pentylfuran (2-Amylfuran)是天然存在的香料成分。
S9383	Methyl palmitate	Methyl palmitate (Methyl hexadecanoate, Palmitic acid methyl ester), a kind of fatty acid methyl ester, could be found in many plants and possesses acaricidal activity.
S9453	2-Undecanol	2-Undecanol (Methyl nonyl carbinol, 2-Hydroxyundecane, 2-Hendecanol) is a fatty alcohol lipid molecule.
S9454	Undecanoic acid	Undecanoic acid (Undecylic acid) is a medium chain length monocarboxylic acid that appears to be involved in the control of triacylglycerol synthesis.
S9385	Ligustilide	Ligustilide is the most abundant bioactive ingredient in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments. 现配现用
S9033	Incensole acetate	Incensole acetate, isolated from Boswellia Resin, is a novel anti-inflammatory compound that inhibits NF-κB activation.
S9043	6-Shogaol	6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties.
S9071	Nootkatone	Nootkatone, a natural ingredient that occurs in grapefruit and certain other plants, has antioxidant and anti-inflammatory effects.
S9094	Pogostone	Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
S9118	Beta-Asarone	Beta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects.
S9140	Pulegone	Pulegone, a naturally occurring organic compound, is a fragrance and flavour ingredient.
S9142	Sparteine	Sparteine, which could be extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent.
S9236	α-Cyperone	α-Cyperone (alpha-cyperone) 是香附子Cyperus rotundus的主要活性成分，表现出了如抗毒力、抗原毒性和抗菌活性等生物活性。α-Cyperone (alpha-cyperone) 与COX-2、IL-6、Nck-2、Cdc42 和 Rac1 的表达下调有关。
S9263	3-n-Butylphathlide	3-n-Butylphathlide, initially isolated from the seeds of Apium graveolens Linn., has shown significant neuroprotective effects.
S5370	10-Hydroxydecanoic acid	10-Hydroxydecanoic acid, a minor constituent of royal jelly, is a saturated fatty acid that has cytotoxic effects.
S9450	1-Undecanol	1-Undecanol (Undecyl alcohol, 1-Hendecanol), found naturally in many foods such as fruits (including apples and bananas), butter, eggs and cooked pork, is used as a flavoring ingredient.
S5761	Citric acid	Citric acid is a weak organic acid that occurs naturally in citrus fruits. It is an intermediate in the citric acid cycle.
S5763	D-Mannose	D-mannose is a naturally occurring simple sugar that may help your body cleanse the urinary tract and maintain a healthy bladder lining.
S5391	α-Boswellic acid	α-Boswellic acid is a naturally occuring triterpenoic acid.
S5757	Isoeugenol	Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
S5759	Methyl linoleate	Methyl linoleate (Linoleic acid methyl ester), found in cloves, is a fatty acid methyl ester of linoleic acid which is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes.
S5756	Methyl Stearate	Methyl Stearate (Methyl Octadecanoate, Stearic Acid methyl ester), found in cloves, is an antifoaming agent and fermentation nutrient.
S5577	6-Biopterin	6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects.
S5743	γ-Linolenic acid	γ-Linolenic Acid (18:3, n-6), the Δ6-desaturase product of linolenic acid, is an unsaturated fatty acid found primarily in vegetable oils.
S5600	Flavokawain A	Flavokawain A 是一种从 kava 提取的凋亡诱导剂和抗癌剂。 Flavokawain A 可以下调抗凋亡蛋白，例如 XIAP、 survivin 和 Bcl-xL，从而改变凋亡与抗凋亡分子之间的平衡、诱导肿瘤细胞死亡。
S5732	Sebacic acid	Sebacic acid (1,8-Octanedicarboxylic acid) is a saturated, straight-chain naturally occurring dicarboxylic acid
S5733	Stearic acid	Stearic acid (Octadecanoic acid, Isostearic acid, Cetylacetic acid) is a natural saturated fatty acid found in animal and vegetable fats. It could be used as a food additive and used in soaps, cosmetics and detergents.
S9375	2'-Hydroxyacetophenone	2'-Hydroxyacetophenone is a flavouring ingredient.
S9379	Dihydrocoumarin	Dihydrocoumarin, a compound found in Melilotus officinalis (sweet clover) and Dipteryx odorata Willd (tonka beans), is added as a flavoring agent to a wide variety of foods, including soft drinks, yogurt, and muffins, and is used as a common fragrance in cosmetics, lotions, and soaps.
S9382	Thymine	Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.
S9333	Gibberellins A4/A7	Gibberellins A4/A7 (Gibberellin A4 and A7) is the Gibberellin A4 Mixture With Gibberellin A7. Gibberellins A4/A7 promotes internode elongation & breaks certain dormancies in seeds. Gibberellins A4/A7 is an endogenous plant growth regulator, promotes the growth and elongation of cells.
S5691	Terpinyl Acetate	Terpinyl Acetate (alpha-Terpinyl), a naturally occuring compound found in several essential oils, is a flavouring agent.
S5616	4-Methylcatechol	4-Methylcatechol (P-Methylcatechol, 3,4-Dihydroxytoluene, Homocatechol) is an inducer of nerve growth factor. It is used to synthesize antimicrobial and antioxidant.
S9352	Homogentisic Acid	Homogentisic Acid (Melanic acid, 2,5-dihydroxyphenylacetic acid) is found in Arbutus unedo (strawberry-tree) honey or present in the bacterial plant pathogen Xanthomonas campestris pv. phaseoli as well as in the yeast Yarrowia lipolytica.
S5684	Lapachol	Lapachol (Tecomin, CI75490, Bethabarra wood, Greenhartin), a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
S5640	Ethyl caffeate	Ethyl caffeate, a naturally occurring compound found in Bidens pilosa, suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2 and PGE2 in vitro.
S5680	(-)-Verbenone	(-)-Verbenone (2-Pinen-4-one), an important component of the essential oil from rosemary, is an insect pheromone with a spicy odor and camphoraceous fragrance.
S5617	Myristic Acid	Myristic acid (Tetradecanoic acid) is a fatty acid that occurs naturally in some foods. Myristic acid inhibits the phosphorylation of poly E4Y by Src with an Ki of 35 μM.
S9046	Berberine	Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.
S9047	Leonurine Hydrochloride	Leonurine (SCM-198), a natural alkaloid extracted from Herba leonuri, is a promising anti-glycation agent with vasodilator, antioxidative, cardioprotective and neuroprotective effects.
S9037	Tenacissoside H	Tenacissoside H, a natural compound found in M. tenacissima, exerts anti-inflammatory and anti-tumor effects.
S9027	Corynoxine	Corynoxine, a natural oxindole alkaloid, is a new autophagy enhancer.
S9041	Corosolic acid	Corosolic acid (Glucosol, Colosic acid, 2α-Hydroxyursolic acid) is one of the pentacyclic triterpenoids isolated from Lagerstroemia speciose and has been reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells.
S9035	Isovitexin	Isovitexin (saponaretin, Apigenin-6-C-glucoside), an active component of many traditional Chinese medicines, has various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.
S9032	Sanguinarine	Sanguinarine (Pseudochelerythrine, Sanguinarin, Sanguinarium), a benzophenanthridine alkaloid known as an anti-inflammatory agent, is a potent inhibitor of NF-κB activation.
S9036	(20R)Ginsenoside Rh2	(20R)Ginsenoside Rh2, a natural compound found in Panax ginseng, shows antiviral and anticancer activities. It is a matrix metalloproteinase (MMP) inhibitor.
S9024	3-O-Acetyl-11-keto-β-boswellic acid (AKBA)	3-O-Acetyl-11-keto-β-boswellic acid (AKBA), the major active ingredient of the gum resin from Boswellia serrata and Boswellia carteri Birdw., exerts anti-inflammatory therapeutic effects and noncompetitively inhibits 5-lipoxygenase, topoisomerase, and leukocyte elastase.
S9044	Ginsenoside F2	Ginsenoside F2, a ginsenoside found in Panax species, is an autophagic initiater with anti-cancer, and anti-obesity activities.
S9042	Wedelolactone	Wedelolactone, a medicinal plant-derived natural compound, is an inhibitor of IKK that is critical for activation of NF-κB by mediating phosphorylation and degradation of IκBα. Wedelolactone is also an inhibitor of caspase-11.
S9030	Tenacissoside I	Tenacissoside I is a natural compound found in M. tenacissima at relatively high level.
S5677	Xanthopterin Hydrate	Xanthopterin, isolated from butterfly wings and found in many other sources, replace folic acid in the nutrition of many animal species.
S9353	L-serine	L-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
S9349	D-(+)-Raffinose pentahydrate	Raffinose is a trisaccharide composed of galactose, glucose, and fructose.
S9341	3,4-Dimethoxycinnamic acid	3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S9344	DL-Methionine	DL-Methionine is an amino acid that has a role in the defence of oxidative stress.
S9004	Chondroitin 4-sulfate	Chondroitin 4-sulfate is an important structural component of cartilage and has been used as a dietary supplement to treat symptoms of joint discomfort.
S9373	Neryl acetate	Neryl acetate (Nerol, Acetic acid neryl ester, cis-Geranyl), a chemical compound found in citrus oils, is a flavouring agent.
S9339	S-(-)-Cotinine	S-(-)-Cotinine, a constituent of tobacco products and the major metabolite of nicotine, stimulates nicotinic receptors to evoke the release of DA in a calcium-dependent manner from superfused rat striatal slices.
S9372	Ethyl palmitate	Ethyl palmitate (Ethyl hexadecanoate, Palmitic acid ethyl ester) is a long-chain fatty acid ethyl ester that is used as a hair- and skin-conditioning agent.
S4937	4'-Hydroxychalcone	4'-Hydroxychalcone (P-Cinnamoylphenol)，存在于草药、香料和茶叶中，是一种刺甘草查尔酮。它具有多种生物活性，能够抑制TNF-α诱导的NF-κB通路激活、并激活BMP信号通路。
S3622	Diammonium Glycyrrhizinate	Diammonium glycyrrhizinate (DG)是一种传统的中草药，从甘草中提取纯化而来。它具有抗炎活性，对生物氧化具有抗性、对膜具有保护性。DG通过抑制NF-κB、TNF-α和细胞间黏附分子1来减少炎症损伤。
S3769	Palmatine	Palmatine (Berbericinine, Burasaine), an isoquinoline alkaloid, has sedative, antidepressant, antioxidative, anti-ulcerative, antacid, anticancer, and anti-metastatic activities.
S3788	Carvacrol	Carvacrol (Cymophenol), monoterpenic phenol isomeric with thymol, has diverse activities such as antimicrobial, antitumor, an-timutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, AChE inhibitory, antielastase, insecticidal, antihepatotoxic and hepatoprotective activities.
S5176	Fructose	Fructose (D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose) is a simple ketonic monosaccharide found in many plants.
S5178	4-Hydroxy-2,5-dimethyl-3(2H)furanone	4-Hydroxy-2,5-dimethyl-3(2H)furanone (furaneol, HDMF) is a naturally occurring substance found in a variety of fruits and has been shown to have antimicrobial activity.
S5592	Vitamin A	Vitamin A (Retinol) is a naturally occuring fat-soluble vitamin that is important for normal vision, the immune system, and reproduction. It also plays roles in normal functioning of heart, lungs, kidneys, and other organs.
S5591	Ectoine	Ectoine ( THP(B)) is a natural amino acid derivate with membrane stabilizing and inflammation reducing capacities. It is produced by bacteria living under extreme harsh environmental conditions where it serves as osmoregulatory compatible solute.
S4888	Guanine	Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA.
S5505	2’-deoxyuridine	2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.
S5503	O-Acetyl-L-carnitine hydrochloride	O-Acetyl-L-carnitine (Acetyl-L-carnitine, O-acetyl-L-carnitine, O-Acetylcarnitine) can be synthesis or is naturally found in healthy humans. It could help transport fatty acids into the mitochondrial matrix where fatty acid metabolism occurs.
S9368	ADP	ADP (Adenosine diphosphate, adenosine pyrophosphate, Adenosine 5'-diphosphate) is an important organic compound in metabolism and is essential to the flow of energy in living cells.
S5550	Ethyl gallate	Ethyl gallat (Phyllemblin, gallic acid ethyl ester), which could be found naturally in a variety of plant sources, is a food additive with antimicrobial activity.
S9390	Astragaloside II	Astragaloside II, extracted from Astragalus membranaceus, has been reported to promote tissue wound repair and could be a potential adjunctive agent in cancer chemotherapy, enhancement of osteogenesis, and modulation of T cell activation.
S9166	Griffonilide	Griffonilide is a natural product that has been reported to induce bone remodeling activity resulting in structural changes.
S9169	Polygalasaponin F
S9198	Obtusifolin	Obtusifolin is anthraquinone found in the seeds of Cassia obtusifolia, has inhibitory effects on platelet aggregation and aldose reductase.
S9220	Stylopine hydrochloride	Stylopine (Tetrahydrocoptisine, Coptisine), a major component of the leaf of Chelidonium majus L., is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.
S9241	Polygalaxanthone III	Polygalaxanthone III 是一种天然产物，具有镇静，减轻感冒，消除痰液和消肿的功效。Polygalaxanthone III 抑制 CYP2E1 催化的氯唑沙宗6-羟基化反应，IC50值为50.56 μM。
S9259	Lithospermic acid	Lithospermic acid, an active component isolated from Salvia miltiorrhiza radix, is known to have multiple pharmacological actions such as antihypertensive and antioxidant effects.
S9262	Raddeanin A	Raddeanin A (Raddeanin R3, NSC382873), a triterpenoid saponin from Anemone raddeana Regel, displays moderate inhibitory activity against histone deacetylases (HDACs) and has high antiangiogenic potency, antitumor activity.
S9264	Decursin	Decursin (D), purified from Angelica gigas Nakai, shows potential anti-inflammatory activity and neuroprotective property.
S9306	Corynoxeine	Corynoxeine, which could be isolated from Uncaria rhynchophylla, is a useful and prospective compound in the prevention and treatment for vascular diseases. It is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation.
S9310	Isorhychophylline	Isorhynchophylline (IsoRhy, 7-Isorhyncophylline) is a major tetracyclic oxindole alkaloid isolated from the Chinese herbal medicine Uncaria rhynchophylla (Miq.)Jacks (Gouteng in Chinese). It acts as a neuronal autophagy inducer with therapeutic potential for cardiovascular and central nervous system diseases.
S9414	Cyasterone	Cyasterone is the main phytoecdysteroid component found in Cyathula capitata. It is a natural EGFR inhibitor and maybe a promising anti-cancer agent.
S9448	D-(+)-Turanose	D(+)-Turanose is a naturally occuring compound. It is a reducing disaccharide.
S5745	Glyceryl 1,3-dipalmitate	Glyceryl 1,3-dipalmitate acts as a metabolite of saccharomyces cerevisiae, plant and human.
S9507	(−)-Norepinephrine	(−)-Norepinephrine (Arterenol, Levarterenol, L-Noradrenaline)是一种天然存在的神经递质和激素。它是adrenergic receptors的激动剂，对α1, α2A和β1肾上腺素受体的Ki值分别为330 nM、56 nM和740 nM。
S9505	Oleanonic Acid	Oleanonic Acid (3-Ketooleanolic Acid, 3-Oxooleanolic acid), extracted from Pistacia terebinthus galls, is a cell cycle inhibitor and used as antitumor agents.
S5686	Tryptanthrin	Tryptanthrin is a natural alkaloidal compound having basic indoloquinazoline moiety. It has broad spectrum of biological activities including anticancer activity, anti-inflammatory, antiprotozoal, antiallergic, antioxidant, and antimicrobial.
S5690	Triacanthine	Triacanthine, which could be isolated from the leaves of G. triacanthos, shows hypertensive activity, also cardiotonic, antispasmodic and a respiratory analeptic.
S5554	Lanatoside C	Lanatoside C 是具有抗病毒和抗肿瘤活性的强心苷。Lanatoside C 通过减弱 MAPK，Wnt，JAK-STAT和PI3K/AKT/mTOR信号通路，诱导G2/M细胞周期停滞并诱导自噬和细胞凋亡。
S5312	Urolithin A	Urolithin A (3,8-Dihydroxy Urolithin, 2',7-Dihydroxy-3,4-benzocoumarin), a metabolite of ellagitannin, is a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption.
S3817	Harmine hydrochloride	Harmine (Telepathine)是属于β-咔啉家族化合物的一种荧光harmala生物碱，是一种高细胞渗透性的 DYRK1A 的激酶口袋结合ATP的竞争性抑制剂，与DYRK2结合IC50值高约60倍。Harmine 还可以抑制 monoamine oxidases (MAOs) 和 cdc-like kinases (CLKs)。Harmine 抑制 5-HT2A serotonin receptor 的Ki值为397 nM。
S5318	Acacetin	Acacetin (Linarigenin, 5,7-dihydroxy-4'-methoxyflavone, 4'-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.
S9345	Disodium 5'-Inosinate	Disodium 5'-Inosinate, widely distributed in all animal and plant tissues, is used as a flavor enhancer.
S9059	4'-O-Glucosylvitexin	4'-O-Glucosylvitexin is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida.
S9364	6-Hydroxycoumarin	6-Hydroxycoumarin demonstrates cytotoxic effect against the cancer cell lines.
S9365	Disodium uridine-5'-monophosphate	Disodium uridine-5'-monophosphate is a nucleotide that is a major component of ribonucleic acid.
S9366	5'-Adenylic acid	AMP, also known as 5'-Adenylic acid and Adenosine monophosphate, is a nucleotide that is found in RNA. It is used as a dietary supplement to boost immune activity, and is also used as a substitute sweetener to aid in the maintenance of a low-calorie diet.
S9369	Xanthosine	Xanthosine (Xanthine riboside) is an intermediate in purine metabolism, formed from IMP, and forming GMP.
S9370	Adenosine Cyclophosphate	Adenosine Cyclophosphate (Cyclic adenosine monophosphate, cAMP, cyclic AMP, 3',5'-cyclic adenosine monophosphate) is useful for improving myocardial hypoxia, dilating coronary artery and strengthening myocardiac contraction.
S9384	Sophocarpine Monohydrate	Sophocarpine, a naturally occurring tetracyclic quinolizidine alkaloid derived from Sophora alopecuroides L, has shown promising therapeutic properties, including anti-inflammatory, anti-nociceptive, and antivirus activities.
S9386	Polygalacic acid	Polygalacic acid 是从远志属植物（Polygala paenea L.）分离出的三萜类四羟酸。Polygalacic acid (0-100μM; 24h) 可以显著降低 MMP-3、MMP-9、MMP-13 和 COX-2 的mRNA表达，这些因子的表达由IL-1β诱导可显著增加，并呈现出剂量依赖性。
S9387	Maackiain	Maackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
S9388	(+)-Praeruptorin A	Praeruptorin A is a coumarin compound naturally occurring in the roots of Peucedanum praeruptorum Dunn., a commonly used traditional Chinese medicine for the treatment of certain respiratory diseases and hypertension. Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation. (+)-Praeruptorin A is one of enantiomers.
S9389	Phorbol	Phorbol is a natural, plant-derived organic compound that exerts a broad range of biological activities.
S9401	3,6'-Disinapoyl sucrose	3,6'-Disinapoyl sucrose (Disinapoyl sucrose), an oligosaccharide ester natural product originating from the root of wild Polygala tenuifolia, has neuroprotective effects and antidepressive activity in rats.
S9400	Rhynchophylline	Rhynchophylline (Mitrinermine), an active component isolated from species of the genus Uncaria, acts as a calcium channel blocker and is widely used in traditional Chinese medicine mainly for treating ailments of central nervous and cardiovascular systems, such as lightheadedness, convulsions, numbness, and hypertension.
S9398	Crassicauline A	Crassicauline A, a diterpenoid alkaloid in Aconitum herbs, is an analgesic drug clinically used in China.
S9397	Alliin	Alliin (S-allyl cysteine sulfoxide, ACSO, 3-(Allylsulphinyl)-L-alanine) is a sulfoxide that is a natural constituent of fresh garlic.
S9396	Geraniin	Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has been shown to possess significant antioxidant activity in vitro.
S9392	Praeruptorin B	Praeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.
S9402	(20R)-Protopanaxadiol	(20R)-Protopanaxadiol, isolated from the roots of Panax ginseng, has protective effect on myocardial ischemia.
S9404	Pristimerin	Pristimerin is a naturally occurring triterpenoid that has been shown to suppress the proliferation of various cancer cell lines at the concentration (IC50) range of 0.2-4 μM, including those of breast, glioma, prostate, pancreatic, ovarian, colon.
S9405	Sesamoside	Sesamoside, a main chemical ingredient iridoid glycoside from Lamiophlomic rotata, has analgesic and anti-inflammatory effects in animal studies.
S9406	Sauchinone	Sauchinone, one of the active lignan isolated from the roots of Saururus chinensis, possesses diverse pharmacological properties, such as hepatoprotective, anti-inflammatory and anti-tumor effects.
S9407	Angoroside C	Angoroside C, an important phenylpropanoid glycoside of the traditional Chinese medicine Scrophulariae Radix, possesses the effects of preventing ventricular remodeling, reducing pulmonary oedema, and reducing blood pressure, as well as having the properties of anti-platelet aggregation, hepatoprotection and anti-nephritis, etc.
S9408	Beta-Elemonic acid	Beta-Elemonic acid (3-Oxotirucallenoic Acid), a known triterpene isolated from Boswellia (Burseraceae), exhibits anti‑inflammatory effects.
S9409	Kavain	Kavain, the main kavalactone found mostly in the roots of the kava plant, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels.
S9410	Euphorbia factor L1	Euphorbia factor L1, a diterpenoid isolated from Euphorbia lathyris, inhibits osteoclastogenesis and induces osteoclast apoptosis.
S9411	Liensinine	Liensinine, an important functional compound in lotus seeds, has anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.
S9412	Flavokawain B	Flavokawain B is a natural chalcone first isolated from extracts of kava roots that induces apoptosis in cancer cells.
S9413	Yangonin	Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
S9416	Triptonide	Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical Wnt/β-catenin signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.
S9417	Homoplantaginin	Homoplantaginin (Hispidulin-7-glucoside) 是中草药丹参中的主要类黄酮，具有抗炎和抗氧化作用。Homoplantaginin 可抑制 TNF-α 和 IL-6 mRNA 表达，IKKβ 和 NF-κB 磷酸化。
S9420	Sinoacutine	Sinoacutine (Salutaridine), isolated from the Chinese drug Ching-fengteng, elicits mild antitussive properties.
S9421	Demethylnobiletin	Demethylnobiletin (5-Demethylnobiletin)是一种在柑橘类水果中发现的独特的类黄酮，具有潜在的化学预防人类癌症的作用。5-Demethylnobiletinin 是 5-LOX 的直接抑制剂，IC50值为0.1 μM，且不影响COX-2的表达。5-Demethylnobiletinin 具有抗炎活性，可抑制大鼠中性粒细胞中 leukotriene B 4(LTB4) 的形成和人中性粒细胞中elastase弹性蛋白酶 (elastase) 的释放，IC50为0.35 μM。
S9422	Diosbulbin B	Diosbulbin B is the main hepatotoxic compound in Airpotato yam, which is traditionally used for treating thyroid disease and cancer.
S9423	Narcissoside
S9425	Trifolirhizin	Trifolirhizin, a natural pterocarcan flavonoid extracted from Sophora flavescens, has many pharmacological activities, such as hepatoprotective, anti-inflammatory, anti-proliferation, and skin-whitening.
S9427	Tabersonine	Tabersonine is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus and shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.
S9428	Brazilin	Brazilin (Natural Red 24) is a red pigment obtained from the wood of the brazilwood family. It is used to dye fabric and has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties.
S9429	6α-Hydroxygeniposide	6α-Hydroxygeniposide, an iridoid glycoside, is a chemical constituents of Pittosporum glabratum Lindl.
S9430	Tomatidine Hydrochloride	Tomatidine Hydrochloride, a natural steroidal alkaloid, possesses potent antibacterial activity and has anti-inflammatory effects in macrophages.
S9431	Dehydrocorydalin	Dehydrocorydalin is an alkaloidal component isolated from Rhizoma corydalis. It has anti-inflammatory and anti-tumor effects and can protect the cardiovascular system.
S9433	Tubeimoside II	Tubeimoside II (Tubeimoside B), a natural triterpenoid saponin isolated from herb, show anti-inflammatory, antitumor, and antitumor-promoting effects.
S9434	8-Gingerol	8-Gingerol is a bioactive ingredient of ginger root (Zingiber officinale), a medicinal plant having anti-nausea, anti-inflammatory, and anti-carcinogenic properties and a carminative effect.
S9435	Secoxyloganin	Secoxyloganin is a secoiridoids that is extensively used in synthetic and biosynthetic studies of monoterpene indole alkaloids and related natural products.
S9436	Pinoresinol dimethyl ether	Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase.
S9437	Echinatin	Echinatin is a licorice extract that displays antioxidant properties and anti-inflammatory activities.
S9438	Isosakuranetin	Isosakuranetin (4'-Methylnaringenin), an O-methylated flavonoid, is the 4'-methoxy derivative of naringenin, a flavanone found in Citrus species.
S9120	Scutellarein	Scutellarein (6-Hydroxyapigenin), extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities.
S9439	Kaurenoic acid	Kaurenoic acid (kaurenoate, kaur-16-en-18-oic acid) is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, the mechanisms may through inhibition of iNOS and COX-2 expression.
S9441	Sibiricose A5	Sibiricose A5, which could be isolated from traditional Chinese medicine Polygalae Radix, shows potent antioxidant activity.
S9442	Bergaptol	Bergaptol (5-Hydroxypsoralen, 5-Hydroxyfuranocoumarin)是在柠檬、佛手柑等柑橘精油中发现的天然呋喃香豆素。Bergaptol 是有效的 CYP3A4 酶脱苄基活性抑制剂，IC50值为24.92 μM。
S9443	Schisantherin B	Schisantherin B is one bioactive of lignans isolated from Schisandra chinensis (Turcz.) Baill which has been commonly used as a traditional herbal medicine.
S9444	Tomatine	Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S9446	Dihydrokavain	Dihydrokavain (Marindinin) is a kavalactone source from kava beverages used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.
S9447	1F-Fructofuranosylnystose	1F-Fructofuranosylnystose is a kind of Fructooligosaccharides which are naturally occurring sugars with potentially beneficial nutritional effects.
S9503	Fraxetin	Fraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.
S9502	Madecassic acid	Madecassic acid (Brahmic acid) 是最早从积雪草中分离的天然三萜，具有多种消炎和抗糖尿病作用，阻断巨噬细胞中的 NF-κB 活化并导致 iNOS、COX-2、TNF-alpha、IL-1beta 和 IL-6 抑制。
S9001	Malic acid	Malic acid (Hydroxybutanedioic acid, 2-Hydroxysuccinic acid) is a common, naturally occurring ingredient in many foods. It is the main acid found in apples and other fruits.
S9002	L-Fucose	Fucose (6-Deoxy-L-Galactose, L-fucopyranose) is found on N-linked glycans on the mammalian, insect and plant cell surface. L-Fucose is claimed to have application in cosmetics, pharmaceuticals, and dietary supplements.
S9006	Perillartine	Perillartine (Perilla sugar, Peryllartine) is a sweetener.
S9014	AstragalosideⅠ	AstragalosideⅠ, is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.
S5083	Lentinan	Lentinan (A823605, Bromoduline)，分离纯化自香菇子实体水煮提取物，是一种真菌多糖免疫调制剂，具有抗肿瘤活性。
S9272	Koumine	Koumine, a Gelsemium alkaloid, possesses analgesic, anti-inflammatory and neurosteroid modulating activities.
S9273	Timosaponin BII	Timosaponin BII (BII, Prototimosaponin AIII) is a steroidal saponin showing potential anti-dementia and antioxidant activity.
S9274	Isochlorogenic acid B	Isochlorogenic acid B, naturally isolated from Laggera alata, has antioxidative and hepatoprotective properties.
S9275	Isoguanosine	Isoguanosine (Crotonoside)抑制 FLT3 和 HDAC3/6 治疗AML。Isoguanosine 是巴豆（Croton tiglium）种子中天然存在的鸟苷的活性异构体。
S9276	Alisol B	Alisol B, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways.
S9277	Alisol A	Alisol A is one of the major active triterpenes isolated from Rhizoma Alismatis (RA), a famous Traditional Chinese Medicine widely used for diuretic, hypolipidemic, anti-nephrolithic, anti-atherosclerotic, anti-inflammatory and anti-diabetic purposes.
S9278	Saikosaponin C	Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.
S9279	Euphorbia factor L3	Euphorbia factor L3 (5,15-Diacetyl-3-benzoyllathyrol), belonging to the lathyrane diterpenoids isolated from Caper Euphorbia Seed, shows potent cytotoxicity and induces apoptosis via the mitochondrial pathway in A549 cells.
S9280	Demethoxycurcumin	Demethoxycurcumin, a natural demethoxy derivative of curcumin, has anti-oxidant, anti-inflammatory, anti-cancer, and anti-angiogenesis properties.
S9281	Peimine	Peimine (Verticine, Wanpeinine A) is a major biologically active component of Fritillaria ussuriensis, exhibits anti-inflammatory and pain suppression properties at the cellular level.
S9267	Epimedin A	Epimedin A is a major component of Herba Epimedii with bioactivities.
S9268	Epmedin B	Epmedin B (Epimedin B) is a component extracted from Epimedii Folium and may have antiosteoporotic activity.
S9269	Epmedin C	Epmedin C (Epimedin C, Baohuoside VI), a flavonoid isolated from the herbs of Epimedium brevicornum Maxim, exhibits immunostimulatory and anticancer activities.
S9270	Dracohodin perochlorate	Dracohodin perochlorate, extracted from Dragon's blood, is widely used in traditional Chinese medicine, especially in wound healing.
S9271	Pulchinenoside A	Pulchinenoside A (Anemoside A3), a natural triterpenoid saponin, is a AMPARs and NMDAR modulator.
S9282	Isochlorogenic acid A	Isochlorogenic acid A (3,5-dicaffeoylquinic acid), isolated from Brazilian propolis and Suaeda glauca, exhibits hepatoprotective and cytotoxic activities.
S9283	Aristolone	Aristolone, which could be extracted from essential oil of Elyonurus hensii, is likely to induce an antalgic activity.
S9284	Aloesin	Aloesin (Aloe resin B) is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.
S9285	Fargesin	Fargesin is a neolignan isolated from Magnolia plants. It is a potential β1AR antagonist through cAMP/PKA pathway.
S9286	Neobavaisoflavone	Neobavaisoflavone, isolated from seeds of Psoralea corylifolia, exhibits inhibitory activity against DNA polymerase and platelet aggregation.
S9287	Genkwanin	Genkwanin (Apigenin 7-methyl ether) is one of the major non-glycosylated flavonoids in herbs. It has a variety of pharmacological effects including anti-inflammatory, anti-bacterial, antiplasmodial, radical scavenging, chemopreventive and inhibiting 17β-Hydroxysteroid dehydrogenase type 1 activities.
S9288	Casticin	Casticin (Vitexicarpin), as the major active substance in Lithospermum erythrorhyzon, had been reported to mediate multiple pharmacological activities such as antioxidation, antiviral, cardiovascular protection, antineoplastic and anti-inflammation.
S9289	Astragalin	Astragalin (kaempferol-3-glucoside, Kaempferol 3-O-glucoside, Kaempferol 3-D-glucoside), a flavonoid from leaves of persimmon and green tea seeds, has anti-tumor, anti-inflammatory and anti-oxidant activities.
S9290	Linarin	Linarin (Acaciin, Buddleoside, Acacetin-7-O-rutinoside), a natural flavonoid cpompound, has pharmacological effects, including anti-inflammatory, neuro-protective, cardioprotective and antioxidative effects.
S9291	Isopimpinellin	Isopimpinellin (5,8-Dimethoxypsoralen) is a natural product synthesized by numerous plant species. It may acts as an anticarcinogen.
S9292	Dictamnine	Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S9293	Isoliquiritin	Isoliquiritin (Neoisoliquritin) is a flavonoid glycoside compound from licorice possessing a broad spectrum of pharmacological activities including antioxidant, anti-inflammatory, and anti-depression activities.
S9294	Gelsemine	Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., is a highly toxic compound and may be a glycine receptor agonist with significantly higher binding affinity for some of these receptors than its native agonist, glycine.
S9295	Dauricine	Dauricine, a plant metabolite isolated from the Asian vine Menispermum dauricum, plays a variety of biological roles in the human body, from inhibiting cancer cell growth to blocking cardiac transmembrane Na+, K+, and Ca2+ ion currents.Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF‐κB signaling pathway in colon cancer cells.
S9296	Fraxin	Fraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
S9297	Kirenol	Kirenol is a biologically active substance isolated from Herba Siegesbeckiae. It has been reported to possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities.
S9298	Corylin	Corylin, a main compound isolated from Psoralea corylifolia L. (Fabaceae), has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties.
S9300	Methylprotodioscin	Methyl protodioscin, a bioactive natural compound isolated from Dioscorea collettii Makino (Dioscoreaceae), has numerous pharmacological activities, including anti-inflammation, lipid-lowering, and anticancer activities.
S9301	Verbenalin	Verbenalin (Verbenalol β-D-glucopyranoside, Verbenalol glucoside, Cornin), an iridoid glycoside found in Verbena officinalis, has been reported to exhibit uterine stimulant activity and demonstrated cardioprotection against experimental myocardial ischemic injury.
S9302	Polyphyllin VI	Polyphyllin VI derived from Paris polyphylla possess anti-cancer activities.
S9303	Saikosaponin B2	Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.
S9304	Platycodin D	Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anti-inflammatory, anti-allergic, cholesterol-lowering and neuroprotective properties.
S9305	Toosendanin	Toosendanin, a triterpenoid extracted from Melia toosendan Sieb et Zucc, possesses broad biological actions from blocking neurotransmission and antibotulism to inducing cell differentiation and apoptosis.
S9307	Shanzhiside methyl ester	Shanzhiside methylester is a principle effective iridoid glycoside of L. rotata and serves as a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist.
S9308	Pulsatilla saponin D	Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla koreana, targets c-Met and exerts antiangiogenic and antitumor activities.
S9309	Micheliolide	Micheliolide, a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, inhibits various inflammatory response and may serve as a neuroprotective agent in neuroinflammation-related neurodegenerative disorders.
S9311	Germacrone	Germacrone, a major activity component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antimicrobial activities.
S9312	Cyanidin-3-O-glucoside chloride	Cyanidin-3-O-glucoside chloride (Kuromanin, Chrysontemin, Glucocyanidin) is a natural product with anti-oxidant and neuroprotective effects.
S9313	Atractylenolide III	Atractylenolide III, a major component of Atractylodes rhizome, has anti-inflammatory and anti-angiogenesis activities.
S9314	Atractylenolide II	Atractylenolide II (AT-II, Asterolide, 2-Atractylenolide), a major sesquiterpenoids isolated from the dried Rhizome of Atractylodes macrocephala, shows a wide range of biological and pharmacological activities, for example, against insomnia and anxiety, neuroprotective, platelet activation and anti-cancer effect.
S9315	Praeruptorin A	Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.
S9316	Polyphyllin II	Polyphyllin II, a natural compound extracted from Rhizoma of Paris polyphyllin, shows hemolytic activity.
S9317	Forsythoside A	Forsythoside A, one of the main active ingredients in Forsythiae fructus, has been shown to possess anti-bacterial and immunomodulatory properties.
S9318	(20R)-Ginsenoside Rh1	(20R)-Ginsenoside Rh1, isolated from the root of Panax Ginseng, exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer.
S9319	Cryptochlorogenic acid	Cryptochlorogenic acid (4-Caffeoylquinic acid, 4-O-Caffeoylquinic acid), a phenolic acid found in various plant species, including Artemisia, honeysuckle, and H. sabdariffa, possesses antioxidant properties.
S9322	Neodiosmin	Neodiosmin (Diosmetin-7-neohesperidoside, Diosmetin-7-O-neohesperidoside), a flavone glycoside isolated from C. aurantium, is a strong antioxidant with potential applications in foods, beverages, and pharmaceutical preparations.
S9324	Alnustone	Alnustone, a naturally occuring compound found in the rhizomes of Curcuma xanthorrhiza, exhibits anti-inflammatory, antihepatotoxic and antiemetic activities.
S9329	Orcinol	Orcinol (5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene), occurs in many species of lichens including Roccella tinctoria and Lecanora, exhibits antimutagenic, antioxidant, antibacterial, radical-scavenging effects.
S9343	Sequoyitol	Sequoia alcohol (Sequoyitol) is isolated from Taxus natural organic compounds, it can be used to treat diabetes and other indications.
S9347	Allitol	Allitol (Allodulcitol) is a rare polyol found in nature that is useful not only as a sweetener, but also as the raw material for production of chemical compounds.
S9348	D-(+)-Trehalose Anhydrous	Trehalose is a non-reducing sugar. It is thought to provide plants and animals with the ability to withstanding periods of dehydration.
S9350	Ethyl 4-Methoxycinnamate	Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S9354	Oxalic acid	Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
S5636	Methyl furan-2-carboxylate	Methyl furan-2-carboxylate (Methyl pyromucate, Methyl 2-furoate) is found in cocoa and cocoa products. It is used in food flavouring and preparation of sesquiterpene lactone.
S3814	Tubeimoside I	Tubeimoside I (Lobatoside H, TBMS1), a triterpenoid saponin, isolated from the tubers of Bolbostemma paniculatum, shows potent antitumor and antitumor-promoting effects.
S8068	Chaetocin	Chaetocin，一类来自毛壳菌属的天然产物，是一类 histone methyltransferase 抑制剂，其对dSU(VAR)3-9，小鼠G9a和粗糙链孢霉 DIM5的IC50分别为0.8 μM, 2.5 μM和3 μM。Chaetocin是一种抗癌药物并是 thioredoxin reductase (TrxR) 的抑制剂。
S3790	Methyl gallate	Methyl Gallate (Methylgallate, Gallic acid methyl ester, Gallicin) is a plant polyphenol with antioxidant, anticancer, and anti-inflammatory activities.
S4800	Daminozide	Daminozide (Aminozide, DMASA, DIMG, B 995, Alar，Kylar，B-NINE, SADH), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1.5±0.7 μM for KDM2A. It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested, with IC50s of 2 μM or less against KDM2A, PHF8, and KIAA1718 and IC50s of 127 μM for KDM3A or greater (mM range) against other demethylases.
S9188	Magnoflorine chloride	Magnoflorine (Escholine, Thalictrine, Corytuberine methochloride), isolated from the rhizome of Sinomenium acutum and from Pachygone ovata, is usually used as an anxiolytic chemical with anti-oxidant, α-tyrosinase inhibitory and anti-inflammationary activities.
S9189	Oroxin A	Oroxin A (Baicalein 7-O-glucoside), an active component isolated from the herb Oroxylum indicum (L.) Kurz, activates PPARγ and inhibits α-glucosidase, exerting antioxidant activity.
S9190	Oroxin B	Oroxin B (Hypocretin-2), one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent, selectively induces tumor-suppressive ER stress in malignant lymphoma cells and has antioxidant activity. Oroxin B significantly inhibits proliferation and induce apoptosis, which may be strongly associated with the inhibiting COX-2/VEGF and PTEN/PI3K/AKT signaling pathway in SMMC-7721 cells, Oroxin B potentially be used as a novel therapeutic agent for liver cancer.COX-2, VEGF, PI3K, and p-AKT expression levels are downregulated, while PTEN is upregulated after Oroxin B treatment.
S9191	Loganic acid	Loganic acid (Loganate) is a naturally occurring iridoid monoterpeneglusoside involved in the biosynthesis of indole alkaloids in Vinca rosea.
S9194	Toddalolactone	Toddalolactone, a natural coumarin, inhibits the activity of recombinant human Plasminogen activator inhibitor-1 (PAI-1) in a dose-dependent manner, yielding an IC50 value of 37.31 ± 3.23 μM.
S9195	Maltotetraose	Maltotetraose, found in many foods, belongs to the class of organic compounds known as oligosaccharides.
S9196	Calceolarioside B	Calceolarioside B (Nuomioside A), found in the herbs of Ajuga becumbens Thunb., has anti-proliferation property.
S9199	Pseudoginsenoside F11	Pseudoginsenoside F11, a natural product found in American ginseng but not in Asian ginseng, is a novel partial PPARγ agonist.
S9200	Pneumocandin B0	Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S9203	Notopterol	Notopterol is a kind of furanocoumarin that possesses anti-inflammatory, analgesic, and anticancer activities.
S9204	Oroxylin A	Oroxylin A (6-Methoxybaicalein) is a flavonoid isolated from Scutellaria root that exhibits multiple pharmacological activities, including anti-oxidative, anti-inflammatory, anti-viral and anti-tumor properties.
S9205	Hydroxygenkwanin	Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, has anti-oxidant ability and can act as tissue factor (TF) inhibitor to prevent thrombosis.
S9206	Hydroprotopine	Hydroprotopine (W1171) is a kind of natural herbal extract.
S9514	Rotundic acid	Rotundic acid (Rutundic acid)是一种天然化合物，对人肝细胞癌（HepG2）、恶性黑色素瘤（A375）、SCLC（NCI-H446）、乳腺癌（MCF-7）和结肠癌（HT-29）细胞系表现出细胞毒活性。Rotundic acid 通过调节 AKT/mTOR and MAPK pathways 诱导细胞周期停滞、DNA损伤和细胞凋亡。
S9207	Gypenoside XVII	Gypenoside XVII (GP-17, Gynosaponin S), a ginsenoside found in Panax species, has neuroprotective effects and is widely used to prevent cardiovascular disease.
S9208	Ginsenoside Rb3	Ginsenoside Rb3 是从人参中提取的天然产物，在心血管疾病包括心肌的缺血/再灌注(I/R)损伤中起着重要作用。在人肾293T细胞中检测了Ginsenoside Rb3(0.1-10 μM)对肿瘤坏死因子TNF-α诱导的 nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) 荧光素酶报告基因的抑制作用，IC50值为8.2 μM。在用10 ng/mL TNF-α处理后的HepG2细胞中，Ginsenoside Rb3 还以剂量依赖性的方式抑制 cyclooxygenase-2 (COX-2) 和 inducible nitric oxide synthase (iNOS) 信使mRNA的诱导诱导表达。
S9209	Tritetradecanoin	Tritetradecanoin, found in Myristica fragrans Houtt., is used as an antiadhesion agent and lubricating agent.
S9210	Ginsenoside Rk1	Ginsenoside Rk1, one of the main elements of Sung Ginseng, has been confirmed as a new endothelial barrier enhancer recently and has anti-cancer activity.
S9211	Eriocitrin	Eriocitrin (eriodictyol 7-rutinoside, Eriodictyol glycoside, Eriodictioside) is a flavone glycoside mainly found in lemon with antioxidant activity.
S9213	Jujuboside A	Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis.
S9214	Jujuboside B	Jujuboside B, one of the saponins isolated from the seeds of Zizyphus jujuba var. spinosa, is used in traditional chinese medicine for treating cardiovascular diseases and neurodegenerative diseases.
S9215	Pinoresinol diglucoside	Pinoresinol diglucoside, one of the major lignans isolated from Eucommia ulmoides Oliver bark, has various pharmacological functions, including antihypertension and prevention of osteoporosis.
S9216	Esculentoside A	Esculentoside A, isolated from the Chinese herb phytolacca esculenta, possesses a broad inhibitory effect on a panel of pro-inflammation molecules with less toxicity.
S9217	Complanatuside	Complanatuside, a flavonoid compound isolated from Astragalus complanatus and Lysimachia christinae, has anti-inflammation, lipid-lowering and hepatoprotective effects.
S9219	Huperzine B	Huperzine B, a natural alkaloid existed in Lycopodium plants, is a novel acetylcholinesterase inhibitor and has neuroprotective effects.
S9221	Ferulaldehyde	Ferulaldehyde (Coniferaldehyde, Ferulyl aldehyde) is a natural intermediate of polyphenol metabolism of intestinal microflora.
S9222	Dipotassium glycyrrhizinate	Dipotassium glycyrrhizinate (Neubormitin) 是从甘草根中分离出来的一种广泛使用的抗炎药。
S9223	Talatisamine	Talatisamine, a delphinine type alkaloid extracted from Aconitum talassicum, is a newly identified K+ channel blocker with hypotensive and antiarrhythmic activities.
S9224	Dehydroandrographolide Succinate	Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S9226	Steviolbioside	Steviolbioside (CCRIS-6025), a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S9228	Schisandrin C	Schisandrin C, a dibenzocyclooctadiene lignan isolated from the fruits of Schisandra chinensis (Turcz.) Baill, has many characteristics including anti-inflammation, anti-tumor, and anti-oxidation.
S9229	Linderane	Linderane, isolated from Lindera strychnifolia vill., is an indirect PDE3 activator and possesses multiple biological effects, including superoxide anion radical-scavenging and antioxidative activity and protective activity against gastritis, gastric ulcers and backache.
S9230	Vaccarin	Vaccarin, a major flavonoid glycoside found in Semen vaccariae, exhibits extensive biological activities including vascular endothelial cell protective effects.
S9231	Schisanhenol	Schisanhenol (Gomisin K3) is a compound derived from the fruit of a traditional Chinese herb Schisandra rubriflora, exhibiting strong inhibition toward UGT2B7.
S9232	Crocin II	Crocin II (Crocin B, Crocetin gentiobiosylglucosyl ester, Tricrocin), a carotenoid chemical compound that is found in the flowers crocus and gardenia, is an antioxidant and neural protective agent.
S9233	Imperialine	Imperialine (Sipeimine, Kashmirine) is an alkaloid found in the bulbs of species of the genus Fritillaria.
S9234	Schaftoside	Schaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission.
S9235	Didymin	Didymin (Neoponcirin, Isosakuranetin-7-O-rutinoside) is a citrus-derived natural compound that kills p53 wild-type as well as drug-resistant p53-mutant neuroblastoma cells in culture. It possesses antioxidant, anti-inflammation and anti-cancer properties.
S9237	Berberrubine	Berberrubine (Beroline, 9-Berberoline), an isoquinoline alkaloid isolated from many medicinal plants, possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects.
S9238	Polygalic acid	Polygalic acid (Senegenic acid), a triterpenoid saponin, shows expectorant, emetic and stimulant effects.
S9239	Isocorynoxeine	Isocorynoxeine (7-Isocorynoxeine)是一种在钩藤(Uncaria rhynchophylla)中发现的主要生物碱，对心、脑血管系统具有广泛的有益作用。Isocorynoxeine 可抑制 5-HT2A receptor 介导的电流反应，IC50值为72.4 μM。
S9240	Isofraxidin	Isofraxidin (6,8-Dimethoxyumbelliferone), a bioactive coumarin compound isolated from the functional foods Siberian ginseng and Apium graveolens, is an anti-bacterial, anti-oxidant, and anti-inflammatory agent.
S9242	Narirutin	Narirutin (Naringenin-7-O-rutinoside, Isonaringin), a flavanone abundant in citrus fruits, possesses anti-inflammatory and anti-oxidative effects.
S9243	Protosappanin B	Protosappanin B (FT-0689654, Q-100961), extracted from Lignum Sappan, possesses anti-inflammation and anti-oxidation properties.
S9244	8-O-acetyl shanzhiside methyl ester	8-O-acetyl shanzhiside methyl ester (Barlerin, ND01), isolated from the leaves of Lamiophlomis rotata Kudo, promotes angiogenesis, which leads to the improvement of functional outcome after stroke.8-O-Acetyl shanzhiside methyl ester can inhibts NF-κB.
S9245	Phellodendrine chloride	Phellodendrine chloride, isolated from the Phellodrndron amurensis, exhibits immunosuppressive and anti-inflammatory activities.
S9246	Tiliroside	Tiliroside, a glycosidic flavonoid, possesses anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activities.
S9247	Isoliensinine	Isoliensinine is an alkaloid produced by the edible plant Nelumbo nucifera. It possesses anti-cancer, anti-fibrosis, anti-proliferative, antioxidant, and anti-inflammatory activities.
S9248	Homoorientin	Homoorientin (Isoorientin, Luteolin-6-C-glucoside) is a flavone that acts as a radical scavenger and an antineoplastic agent.
S9249	Securinine	Securinine, a major natural alkaloid product from the root of the plant Securinega suffruticosa, acts as a γ-amino butyric acid (GABA) receptor antagonist.
S9250	Isosilybin	Isosilybin (Silymarin, Silybin B, Isosilybinin, Q-100795)是一种在水飞蓟(S. marianum)果实提取物中发现的黄烷醇，具有抗氧化和抗癌活性。Isosilybin 抑制 CYP3A4 诱导，IC50为74 μM。
S9251	Oxypeucedanin	Oxypeucedanin is a major coumarin aglycone that can be extracted from Ostericum koreanum. It is a kind of open-channel blocker of the hKv1.5 channel.
S9252	Corydaline	Corydaline is a bioactive alkaloid with various anti-acetylcholinesterase, anti-allergic, and anti-nociceptive activities found in the medicinal herb Corydalis Tubers.
S9253	Coixol	Coixol (6-methoxybenzoxazolone, MBOA) acts as a central muscle relaxant with an anti-convulsant effect.
S9254	Skimmin	Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent.
S9255	Isoscopoletin	Isoscopoletin (7-Methoxyesculetin) is a member of the class of compounds known as hydroxycoumarins. Isoscopoletin can be found in coriander and eggplant, which makes isoscopoletin a potential biomarker for the consumption of these food products.
S9256	Isobavachin	Isobavachin is a flavonoid compound obtained from Psoralea Corylifolia Linn.
S9257	Acetylshikonin	Acetylshikonin is a biologically active compound with anti-cancer and anti-inflammatory activity, which is isolated from the roots of Lithospermum erythrorhizoma. It is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s.
S9258	(+)-Isocorynoline	Isocorynoxeine, a major bioactive tetracyclic oxindole alkaloids found in Uncaria rhynchophylla, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM and shows various beneficial effects, including lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage.
S9260	Nodakenin	Nodakenin ((+)-Marmesinin), a coumarin compound, acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM.
S9265	7-Epitaxol	7-Epitaxol (7-Epipaclitaxel) is the major derivative of taxol found in cells. Taxol (paclitaxel) is a well-known natural-source cancer drug.
S9266	Ginsenoside Rc	Ginsenoside Rc, isolated from Panax ginseng, may exert various activities including anti-cancer, anti-inflammatory, antiobesity, and anti-diabetic effects.
S9186	Liensinine perchlorate	Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
S9187	Phillygenin	Phillygenin (Sylvatesmin), a bioactive intergradient in Osmanthus fragrans, has anti-inflammatory, anti-obesity and antipyretic activities. It could reduce blood lipid levels and low density lipoprotein.
S9517	Liriope muscari baily saponins C	Liriope muscari baily saponins C, extracted from the roots of Liriope muscari (Decne.) Baily, induces autophagy and has an anti-thrombotic activity.
S9201	Levistilide A	Levistilide A (Diligustilide), a natural compound isolated from the traditional Chinese herb Ligusticum chuanxiong Hort, is a potential P-gp modulator and used for treating cancer.
S9512	1,3-Dicaffeoylquinic acid	1,3-Dicaffeoylquinic acid (Cynarin; Cinarine; 1,5-Dicaffeoylquinic acid) is a phenolic compound found in artichoke. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.
S9114	Polyphyllin I	Polyphyllin I 是从巴黎茶树素中提取的小分子单体，用于治疗传染病和癌症。 Polyphyllin I 抑制U251细胞增殖并诱导其凋亡。 Polyphyllin I 是 JNK 信号传导途径的激活剂，具有潜在的抗神经胶质瘤作用。
S9115	Wogonoside	Wogonoside (Oroxindin, Wogonin 7-O-glucuronide, Glychionide B), the main flavonoid component derived from the root of Scutellaria baicalensis Georgi, displays anti-inflammatory, anti-angiogenic, and anticancer chemotherapeutic activities.
S9116	Chikusetsusaponin IVa	Chikusetsusaponin IVa (Calenduloside F) 是三萜类皂苷的主要活性成分，具有多种药理活性，包括对各种癌细胞的细胞毒活性，抗炎活性，预防龋齿和诱导人五味子霉素肾毒性。Chikusetsusaponin IVa 也是一种新型的 AMPK 激活剂。
S9117	(20S)Ginsenoside Rg2	(20S)Ginsenoside Rg2, a constituent existing in red ginseng, has been reported to exert strong inhibitory action on various cancer cells.
S9119	Leonuride	Leonuride (Ajugol), an active alkaloid that is extracted from Traditional Chinese Medicine Herba leonuri, is a terpene glycoside that can be used for some gynecological disease.
S9121	Irigenin	Irigenin, an O-methylated isoflavone, can be isolated from the rhizomes of the leopard lily (Belamcanda chinensis), and Iris kemaonensis.
S9122	Tectorigenin
S9123	Eriodictyol	Eriodictyol, a flavonoid extracted from yerba santa, has anti-inflammatory and antioxidant activities and taste-modifying properties.
S9125	Apigetrin	Apigetrin (Cosmetin, Cosmosioside, Thalictiin, Cosmosin, Apigenin 7-glucoside), a flavonoid found in many plant leaves and seeds, has been known to possess antimutagenic, anti-cancer, antioxidant and anti-inflammatory properties.
S9126	Schizandrol B	Schizandrol B (Gomisin A, Besigomsin, Wuweizi alcohol B, Gamma-Schisandrin), extracted from the fruit of Schisandra chinensis Baill., exhibits potent antitumor activities.
S9127	Carnosol	Carnosol is a naturally occurring phenolic diterpene found in rosemary. It has anti-oxidant, anti-inflammatory and anti-cancer activities.
S9128	Isoacteoside	Isoacteoside, a phenylethanoid isolated from Monochasma savatieri Franch. ex Maxim., is an anti‐inflammatory herb widely used in traditional Chinese medicine.
S9129	20(S)-Ginsenoside Rh1	20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1)是从红参中提取的主要生物活性化合物之一，在世界范围内，红参已越来越多地用于增强认知和身体健康。它具有抗发炎、抗氧化、免疫调节作用和对神经系统有积极作用的有效特性。20(S)-Ginsenoside Rh1 可抑制 PPAR-γ、TNF-α、IL-6 和 IL-1β 的表达。
S9130	Rubusoside	Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties.
S9131	Punicalagin	Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.
S9132	Harpagide	Harpagide, isolated from the secondary roots of Harpagophytum procumbens (Hp), has valuable medicinal properties, such as anti-inflammatory, analgesic and potential antirheumatic effects.
S9133	Chicoric acid	Chicoric acid (Dicaffeoyltartaric acid), identified in many plants, exerts various properties include anti-cancer, anti-obesity, antiviral, and anti-diabetic effects.
S9134	Spinosin	Spinosin (Flavoayamenin), a ﬂavone-C-glycoside, is a bioactive ingredient isolated from a traditional Chinese herb Zizyphi Spinosi Semen. It acts as a plant metabolite and an anxiolytic drug.
S9135	Artemisic acid	Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.
S9136	Neochlorogenic acid	Neochlorogenic acid (Neochlorogenate, 5-O-Caffeoylquinic acid) is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S9137	Erianin	Erianin, a natural product derived from Dendrobium chrysotoxum, has been used as an analgesic in traditional Chinese medicine and is a potential anti-tumor agent. Erianin can inhibit IDO-induced tumor angiogenesis.
S9138	Picfeltarraenin IA	Picfeltarraenin IA is an AChE inhibitior, and an potential PI3K and EGFR inhibitor. It also acts as an inhibitor on both the classical and alternative pathways of the complement system.
S9141	Berbamine	Berbamine (BA, BBM) 是一种从中草药黄芦木中分离而来的双苄基异喹啉类天然产物。它是bcr/abl的新型抑制剂，具有有效的抗白血病活性，是NF-κB的抑制剂。Berbamine (BA, BBM) 通过靶向 Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) 抑制癌细胞的生长，并诱导人骨髓瘤细胞凋亡。
S9143	Ammonium Glycyrrhizate	Ammonium glycyrrhizate (Glycamil, Glycyrram) is an ammonium salt extract isolated from licorice root and is commonly used as a flavoring agent and is also used in fragrances, and skin and hair care products.
S9144	Solasonine	Solasonine, a natural glycoalkaloid compound, has anti-inflammation and anti-tumor properties.
S9145	Solamargine	Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum, induces potent, non-selective cytotoxicity and P-gp inhibition.
S9146	Anwuligan	Anwuligan (Macelignan), a natural compound isolated from Myristica fragrans Houtt, has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities.
S9148	Peiminine	Peiminine (Verticinone, Zhebeinone, Raddeanine), a biologically active component extracted from Fritillaria walujewii Regel, has been reported to have potent anti-inflammatory, antitussive, and expectorant effects. It induces autophagic cell death thus represses colorectal carcinoma tumor growth.
S9149	Benzoylpaeoniflorin	Benzoylpaeoniflorin, a natural product isolated from Chinese paeony root, could inhibit COX-1 and COX-2 in vitro.
S9150	Daurisoline	Daurisoline, a bis-benzylisoquinoline alkaloid isolated from the rhizomes of Menispermum dauricum, is a potent autophagy blockers with antiarrhythmic effects.
S9151	Praeruptorin E	Praeruptorin E, isolated from Peucedanum praeruptorum Dunn., is a cardiotonic agent with selective cardiac calcium channel agonistic effect.
S9152	Epiberberine	Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean).
S9153	Betulinicaldehyde	Betulinicaldehyde (Betulinal, Betunal), isolated from the bark of tectona grandis., is an anti-tumor agent.
S9154	Chelidonine	Chelidonine (Stylophorin, Helidonine), a major bioactive, isoquinoline alkaloid ingredient in Chelidonium majus, exhibits anti-inflammatory properties and acetylcholinesterase and butyrylcholinesterase inhibitory activity.
S9155	Aurantio-obtusin	Aurantio-obtusin is a natural effective compound isolated from Semen Cassiae, which possesses hypotensive and hypolipidemic effects.
S9156	Chonglou Saponin VII	Chonglou Saponin VII (Dioscinin, Polyphyllin-VII, Paris saponin-VII), a kind of steroidal saponins from Chonglou (Rhizoma Paridis Chonglou), inhibits EMT and reduces the invasion of ovarian cancer cells via the GSK-3β/β-catenin signaling pathway.
S9157	Neoandrographolide	Neoandrographolide, a principle diterpenoids isolated from A. paniculata, exerts a wide range of therapeutic actions, including immunosuppressant, antithrombotic, anti-inflammatory, antineoplastic, anti-viral, anti-bacterial, anti-diabetic, anti-oxidative stress, antipyretic, anti-edematogenic, and anti-nociceptive activities.
S9159	momordin-Ic	Momordin Ic, a natural triterpenoid saponin, is a novel SENP1 (SUMO-specific protease 1) inhibitor that inhibited proliferation of prostate cancer cells in vitro and in vivo.
S5742	Deferoxamine mesylate (Ba 33112)	Deferoxamine mesylate (Ba 33112, Desferrioxamine B, DFOM, NSC 644468)是Deferoxamine的甲磺酸盐，它可形成铁络合物并用作螯合剂。Deferoxamine 是一种铁死亡的抑制剂，可在体外低氧和高血糖状态下稳定 HIF-1α 的表达并改善HIF-1α的活性。Deferoxamine 可降低 beta-amyloid (Aβ) 的沉积并诱导自噬。
S9160	Ziyu-glycoside I	Ziyuglycoside I is one of the major active ingredients in Sanguisorba officinalis and could be used as an active ingredient for cosmetics.
S9161	Ziyuglycoside II	Ziyuglycoside II is an active compound of Sanguisorba officinalis L. that has anti-inflammation, antioxidation, antibiosis, and homeostasis properties.
S9162	Rubimaillin	Rubimaillin (Mollugin), found in the Chinese medical plant Rubia cordifola, is a dual inhibitor of acetyl-CoA cholesterol acyltransferase 1 (ACAT1) and acetyl-CoA cholesterol acyltransferase 2 (ACAT2), but is more selective for the ACAT2 isozyme.
S9163	Rhapontigenin	Rhapontigenin (Protigenin), produced from rhapontin isolated from a methanol extract of Rheum undulatum roots by enzymatic transformation, is a selective inactivator of cytochrome P450 1A1 (IC50 = 400 nM).
S9164	Curdione	Curdione, one of the major components of Curcuma zedoaria, shows an excellent antithrombotic activity in vivo.
S9165	Poncirin	Poncirin (Isosakuranetin-7-neohesperidoside), extracted from trifoliate orange, has anti-bacterial and anti-inflammatory activities.
S9167	Columbin	Columbin, a diterpenoid furanolactone, is a potential anti-inflammatory drug.
S9168	Periplogenin	Periplogenin (Desoxostrophanthidin, 5-beta-Hydroxydigitoxigenin), isolated from Lagenaria siceraria, has potent anti-psoriatic effects in vitro and in vivo.
S9171	Harpagoside	Harpagoside, a natural product found in the plant Harpagophytum procumbens, has potent anti-rheumatic, anti-inflammatory and analgesic effects.
S9172	Phellodendrine	Phellodendrine, a quaternary ammonium alkaloid extracted from the dried bark of Phellodendrom chinensis Schneid and Phellodendrom amurense Rupr, has the effect of suppressing cellular immune response, reducing blood pressure and antinephritis.
S9173	Sec-O-Glucosylhamaudol	Sec-O-Glucosylhamaudol (Hamaudol 3-glucoside) is one of the major bioactive compounds of the Saposhnikoviae Radix.
S9174	Xanthotoxol	Xanthotoxol (8-Hydroxypsoralen, 8-Hydroxypsoralene, 8-Hydroxyfuranocoumarin, Psoralen), a biologically active linear furocoumarin found in a large number of plants, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
S9175	Macranthoidin A	Macranthoidin A, found in the herbs of Lonicera japonica Thunb., has anti-inflammation activity.
S9176	Pimpinellin	Pimpinellin is a furocoumarin that acts as antagonist of proteins with GABA receptor activity.
S9177	Gypenoside XLIX	Gypenoside XLIX, a naturally occurring gynosaponin, is a selective peroxisome proliferator-activated receptor (PPAR)-alpha activator.
S9178	Sinapine thiocyanate	Sinapine thiocyanate is the thiocyanate salt form of Sinapine, which shows favorable biological activities such as antioxidant and radio-protective activities.
S9179	Catharanthine hemitartrate	Catharanthine hemitartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine.
S9180	Tussilagone	Tussilagone, isolated from the flower of buds of Tussilago farfara (Compositae), is a sesquiterpenoid that is used as a traditional oriental medicine for asthma and bronchitis. It shows anti-inflammatory activity in in vitro studies.
S9181	Periplocin	Periplocin (Periplocoside)是从传统草药皮质骨膜中提取的，具有心脏和抗癌活性。Periplocin 可以显著地促进成纤维细胞L929细胞的增殖、迁移和刺激胶原蛋白的产生，这取决于 Na/K-ATPase 介导的Src/ERK和PI3K/Akt信号通路的激活，从而促进伤口愈合。
S9182	Crebanine	Crebanine, an aporphine alkaloid isolated from the crude hexane extract of the dried tuber of Stephania venosa, exhibits anti-cancer effects.
S9183	Ruscogenin	Ruscogenin, a major steroidal sapogenin of traditional Chinese herb Radix Ophiopogon japonicus, has been reported to exert significant anti-inflammatory and anti-thrombotic activities.
S9184	Forsythoside B	Forsythoside B 是从中药民间植物轮枝（Lamiophlomis rotata Kudo）的叶子中分离出来的一种苯乙胺类苷。Forsythoside B 具有有效的神经保护作用，并具有抗发炎、抗氧化和防腐特性。Forsythoside B 可以抑制 TNF-alpha、IL-6、IκB 并调节 NF-κB。
S9185	Nitidine Chloride	Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
S9455	Isorhamnetin 3-O-neohesperoside	Isorhamnetin 3-O-neohesperoside is the major active substance of Puhuang, a traditional herb medicine widely used in clinical practice to tackle many chronic diseases. It has signiﬁcant biological and pharmacological activities, including antioxidant, antiatherogenic and antimicrobial effects.
S9511	Crocin I	Crocin-I是藏红花素家族的主要成员之一，具有抗抑郁活性，并可改善慢性皮质酮诱导的小鼠脂质代谢破坏和肠道菌群失调。
S9515	Polyphyllin VII	Polyphyllin VII (Y-0166), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.
S5129	D-Aspartic acid	D-Aspartic acid (D-Asp, Aminosuccinic acid, asparagic acid, asparaginic acid) is an endogenous amino acid occurring in several tissues and cells of both invertebrates and vertebrates. It can regulate testosterone synthesis and may act on a stimulatory receptor (NMDA).
S9055	Salvianolic acid A	Salvianolic acid A (Dan Phenolic Acid A), a water-soluble compound extracted from Radix Salvia miltiorrhiza (Danshen), is an antioxidant and free radical scavenging compound that also acts as an inhibitor of the protein-protein interaction mediated by SH2 domains of Src-family kinases Src and Lck.
S9052	Auraptene	Auraptene (7-geranyloxycoumarin)是源自柑橘类植物的天然香豆素，具有重要的药理特性，包括抗癌，抗炎，抗幽门螺杆菌，抗原毒性和神经保护作用。Auraptene 可抑制 matrix metalloproteinase 2 (MMP-2) 以及关键的炎症介质，包括 IL-6、IL-8 和 chemokine (C-C motif) ligand-5(CCL5)。
S9045	Triptophenolide	Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
S9061	Hydroxy safflor yellow A	Hydroxy safflor yellow A, a monomer extracted from Carthamus tinctorius L., possesses various kinds of bio-activities, including anti-oxidation, anti-inflammatory actions, anti-platelet aggregation, anti-tumor and anti-myocardial injury effects.
S9062	4-Hydroxyisoleucine	4-Hydroxyisoleucine, an atypical branched-chain amino acid derived from fenugreek, has effects on the glucose and lipid metabolism, stimulates glucose-dependent insulin secretion and reduces insulin resistance in muscle and/or liver.
S9063	Harringtonine	Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S9064	Trilobatin	Trilobatin (P-Phlorizin), a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S9065	Songorine	Songorine, a ubiquitous alkaloid in the genus Aconitum, is a novel antagonist of the GABAA receptor in rat brain and has antiarrhythmic, antinociceptive, anti-inflammatory, regenerative and CNS-modulating properties.
S9066	Specnuezhenide	Specnuezhenide (Nuezhenide), one of the main ingredients of Chinese medicine, has anti-angiogenic and vision improvement effects.
S9067	Pseudoprotodioscin	Pseudoprotodioscin is a steroidal saponin from plants and exhibits anti-inflammatory and anticancer activities. Pseudoprotodioscin inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides.
S9068	Trillin	Trillin (Disogluside, Diosgenin glucoside) is an active ingredient isolated from Trillium tschonoshii Maxim and acts as a potential anti-inflammatory drug for chronic hepatic inflammation.
S9069	Jatrorrhizine chloride	Jatrorrhizine chloride (Neprotine, Yatrorhizine) is the hydrochloride salt form of jatrorrhizine, which is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S9070	Isoxanthohumol	Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S9072	Sweroside	Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S9073	Lithospermoside	Lithospermoside (Griffonin), extracted from the roots of Lithospermum purpurocaeruleum and L.officinale (Borginaceae), and Thalictrum rugosum and T. dasycarpum (Ranunculaceae), has anti-oxidant, anti-tumor promoting activities.
S9074	Buddlejasaponin IVb	Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells.
S9075	Mulberroside A	Mulberroside A 是从 Morus alba 根的乙醇提取物中分离出的，具有抗酪氨酸酶和抗氧化活性，并被广泛用作化妆品中的活性成分。Mulberroside A 降低 TNF-α、IL-1β 和 IL-6 的表达并抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。
S9076	Typhaneoside	Typhaneoside is a flavonoid glycoside plant extract that has an inhibitory effect on the proliferation of human umbilical arterial smooth muscle cell(HUASMC).
S9077	Plantamajoside	Plantamajoside (Y0160, C10485), a hydroxycinnamic acid, is used as a biomarker in chemotaxonomical studies, and is a compound with numerous biological applications and considerable pharmacological potential.
S9078	Epigoitrin	Epigoitrin (Goitrin, BA-51-090278), the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
S9079	Ginsenoside Rb2	Ginsenoside Rb2 (Ginsenoside C) is a ginsenoside found in Panax ginseng that has a role as a plant metabolite, an antiviral agent and a hypoglycemic agent.
S9080	Anhydroicaritin	Anhydroicaritin (Cycloicaritin), a prenylated flavonoid natural product, is commonly recognized as one of the effective compounds of Epimedii Herba and exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. It is a potent inhibitor of transcription factor SREBPs.
S9081	Anemoside B4	Anemoside B4 (Pulchinenoside B4, Chinensioside A, Pulchinenoside C, Pulsatilla saponin B4), extracted from the herb of Pulsatilla chinensis (Bge.) Regel, is a potential antiviral constituent and inhibits the secretion of IL-10.
S9082	Manninotriose	Manninotriose, found in many foods, is a novel and important player in the RFO metabolism of red dead deadnettle.
S9083	Rhapontin	Rhapontin (Ponticin, Rhaponticin, Rhapontigenin glucoside), a stibene-type glycoside distributed widely in medicinal plants of Rheum genus (Polygonaceae), has anti-inflammatory effect and anti-proliferative activity.
S9084	Rhoifolin	Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
S9085	Corynoline	Corynoline is one of the major active components of many ethnopharmacological plants and exhibits anti-tumor, anti-inflammatory and hepatoprotective activities, etc.
S9111	Isorhamnetin	Isorhamnetin (3-methylquercetin, 3'-Methoxyquercetin, Isorhamnetol), a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.
S9112	Kaempferitrin	Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S9113	Ononin	Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
S9101	Ingenol	Ingenol, a plant-derived diterpenoid, is a weak PKC activator and possesses important anticancer activity.
S9019	Quillaic acid	Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity.
S9020	Dihydrotanshinone I	Dihydrotanshinone I (15,16-dihydrotanshinone I) is a naturally occurring compound extracted from Salvia miltiorrhiza Bunge, also known as Chinese sage, red sage root, and the Chinese herbal Dan Shen. It is a potent inhibitor of the HuR:RNA interaction, active in the low nanomolar range, mainly by limiting the association rate of HuR with RNA.
S9021	(20R)Ginsenoside Rg3	(20R)Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It has a role as an antioxidant and a plant metabolite.
S9022	20S-Ginsenoside Rg3	20S-Ginsenoside Rg3 is extracted from traditional Chinese medicine, red ginseng. It exihits neuromodulatory, cognition enhancing, anti-inflammatory, antioxidative, anti-angiogenic, and anticancer activities.
S9023	20S-Ginsenoside Rh2	20S-Ginsenoside Rh2 is a ginsenoside found in Panax species and inhibits cancer development, progression, and metastasis.
S9026	Hastatoside	Cimifugin is a bioactive component of Saposhnikovia divaricata, a Chinese herb for treating allergy.
S9029	Prim-o-glucosylcimifugin	Prim-O-glucosylcimifugin (Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside) 是防风(Radix Saposhnikovia)中的主要成分，长期以来一直应用于传统中医药中治疗发热、风湿和癌症，它表现出潜在的抗癌活性。在LPS激活的 RAW 264.7 巨噬细胞，Prim-O-glucosylcimifugin 可以浓度依赖性的方式下调 NO synthase (iNOS) 和 cyclooxygenase 2 (COX-2) 的mRNA和蛋白质表达。
S9031	Gambogenic acid	Gambogenic Acid, identified from Gamboge, is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects. Gambogenic acid acts is also an effective inhibitor of EZH2 that specifically and covalently binds to Cys668 within the EZH2-SET domain, and triggers EZH2 ubiquitination.
S9034	Isochlorogenic acid C	Isochlorogenic acid C (3,4-Dicaffeoylquinic acid; 4,5-Dicaffeoylquinic acid), which is a di-O-caffeoyl derivative of chlorogenic acid, is a well-known antioxidant from herbal plants and shows anti-viral effects against EV71.
S9039	Albiflorin	Albiflorin, a natural product isolated from Paeoniae Radix, is a novel 5-HT and NE reuptake inhibitor with high selectivity.
S9040	Maslinic acid	Maslinic Acid (Crategolic Acid, 2α-Hydroxyoleanoic Acid), a Natural Triterpene, exerts a wide range of biological activities, i.e. antitumor, antidiabetic, antioxidant, cardioprotective, neuroprotective, antiparasitic and growth-stimulating. MA significantly suppresses the DNA-binding activity of NF-κB p65 in LPS-induced RAW 264.7 cells.
S9054	Pectolinarin	Pectolinarin 是Cirsium setidens的一种主要化合物，具有抗炎活性。Pectolinarin 可抑制 IL-6 和 IL-8 的分泌以及 PGE2 和 NO 的产生。Pectolinarin 通过 PI3K/Akt 信号通路的失活来诱导凋亡。
S9050	Boldine	Boldine, isolated from Peumus boldus, has alpha-adrenergic antagonist activities in vascular tissue with anti-oxidant, hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.
S9049	Parishin A	Parishin A, isolated from the rhizomes of Gastrodia elata, has good neuroprotective effects against brain disorders.
S9060	Nystose	Nystose (1,1-Kestotetraose, Fungitetraose), a constituent of seeds of onions and roots of Asparagus, is a low-calorie sweetening agent for food and chewing gum.
S9092	Norisoboldine	Norisoboldine (Laurelliptine), a natural aryl hydrocarbon receptor (AhR) agonist, attenuates ulcerative colitis (UC) and induces the generation of Treg cells.
S9093	Nardosinone	Nardosinone, isolated from Nardostachys root, an important Chinese herbal medicine, is an enhancer of nerve growth factor and possesses a wide range of pharmacological effects, including sedative, adaptogen-like, anti-depressive, anti-leukemic, anti-tumorous, and anti-trypanosomal activities.
S9097	Alisol B Acetate	Alisol B acetate, a triterpene from Alismatis rhizoma, induces Bax up-regulation and nuclear translocation, the activation of initiator caspase-8 and caspase-9, and executor caspase-3, suggesting the involvement of both extrinsic and intrinsic apoptosis pathways.
S9098	Dehydrodiisoeugenol	Dehydrodiisoeugenol, a naturally occurring lignan from Aristolochia taliscana (Aristolochiaceae), acts as a potent anti-inflammatory agent and shows various pharmacological activities, including anti-lipid peroxidation, anti-bacteial function, and hepatic drug metabolism enzyme inhibition.
S9099	Orientin	Orientin (Lutexin, Luteolin-8-glucoside), isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S9100	Fraxinellone	Fraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities.
S9102	Magnolin	Magnolin is a natural compound abundantly found in Magnolia flos targeting ERK1 (IC50=87 nM) and ERK2 (IC50=16.5 nM) and inhibits cell transformation induced by tumor promoters such as epidermal growth factor (EGF).
S9103	Ginsenoside Ro	Ginsenoside Ro (Chikusetsusaponin V), one of the high-abundance saponins in ginseng, is widely used as a dietary supplement and has many health-promoting effects.
S9104	Maltopentaose	Maltopentaose is a substrate for energy metabolism and carbon for E. coli.
S9105	Ginsenoside CK	Ginsenoside CK is a ginsenoside found in Panax species and has a role as a plant metabolite, an antineoplastic agent, a hepatoprotective agent, an anti-allergic agent and an anti-inflammatory agent.
S9108	Timosaponin A3	Timosaponin A3 (Filiferin B, AneMarsaponin A3), one of the major steroidal saponin components isolated from Anemarrhena asphodeloides, displays promising pharmacological activity in improving learning, memory, and antineoplastic activity.
S9056	Tuberostemonine	Tuberostemonine, a natural product found in Stemona phyllantha and Stemona tuberosa, is an alkaloid and a metabolite.
S9053	Irisflorentin	Irisflorentin derived from the roots of Belamcanda chinensis (L.) DC. is an herb which has been used for the treatment of inflammatory disorders in traditional Chinese medicine.
S9051	Asperuloside	Asperuloside, an iridoid glycoside found in Herba Paederiae, is a component from traditional Chinese herbal medicine and exerts anti-inflammatory effect.
S9048	(+)-Gallocatechin	(+)-Gallocatechin, found notably in green tea, has moderate affinity to the human cannabinoid receptor and acts as an antioxidant.
S9057	Sinigrin	Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
S9058	Gallocatechin gallate	Gallocatechin galleate (GCG) is a polyphenol originally derived from a variety of sources, including green tea, coffee, safflower, and almonds.
S9086	Dihydrocapsaicin	Dihydrocapsaicin (6,7-Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide, CCRIS1589), found in pepper (C. annuum), is a potential nutriceutical.
S9088	Calycosin-7-O-beta-D-glucoside	Calycosin-7-O-beta-D-glucoside, an isoflavone glycoside isolated from A. mongholicus and A. membranaceus, has antioxidant, anti-inflammatory, and neuroprotective biological activities.
S9089	Magnoflorine	Magnoflorine (Escholin, Thalictrin), an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.
S9090	Corilagin	Corilagin, discovered in many medicinal plants such as Phyllanthus speices etc., has multiple activities including anti-oxidative, anti-inflammatory, anti-apoptotic, hepatoprotective and others. It is an inhibitor of TNF-α.
S9091	10-Gingerol	10-Gingerol is a bioactive compound found in ginger with anti-inflammatory and antioxidant activity.
S9095	Senegenin	Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity.
S9096	ligustroflavone	Ligustroflavone (Nuezhenoside), isolated from the leaves of Turpinia montana, shows high antioxidant capacity and is reported to be an AMPK activator.
S9106	Eleutheroside E	Eleutheroside E, a principal component of Eleutherococcus senticosus (ES), has anti-inflammatory effects by inhibiting NF-κB and protecting against myocardial infarction.
S9107	Glycitein	Glycitein is an aglycone isoflavone found in soy and red clover and exhibits a wide variety of beneficial properties, including neuroprotective, antioxidative, anticancer, anti-osteoporotic, and anti-atherosclerotic activities.
S9109	1-Kestose	1-Kestose (1F-beta-D-Fructosylsucrose), a fructooligosaccharide, could efficiently stimulates Faecalibacterium prausnitzii as well as Bifidobacteria in humans.
S9110	Morin	Morin (Al-Morin, Aurantica, Calico Yellow, Toxylon pomiferum), a constituent of various woods, has a role as an antioxidant, a metabolite, an antihypertensive agent, a hepatoprotective agent, a neuroprotective agent, an anti-inflammatory agent, an antineoplastic agent, an antibacterial agent, a DNA topoisomerase inhibitor and an angiogenesis modulating agent.
S4700	4-Aminobutyric acid (GABA)	4-Aminobutyric acid (4-Aminobutanoic acid, GABA, Gamma-aminobutyric acid, Piperidic acid)是一种天然存在的神经递质，具有抑制中枢神经系统的活性。
S5580	Arabic gum	Arabic gum, derived from exudates of Acacia senegal or Acacia seyal trees, is a complex polysaccharide indigestible to both humans and animals and considered as a safe dietary fiber.
S3774	Dehydroandrographolide Succinate Potasium Salt	Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.
S9008	20-Deoxyingenol	20-Deoxyingenol is a natural compound isolated from the seeds of Euphorbia lathyris L.
S5145	Protoporphyrin IX	Protoporphyrin IX (PPIX) is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway.
S5288	Estropipate	Estropipate (Piperazine estrone sulfate, Estrone sulfate piperazine salt, Pipestrone) is a natural estrogenic substance composed of estrone sulfate and piperazine and is used mainly in menopausal hormone therapy in the treatment of menopausal symptoms.
S3917	Tetrahydrocurcumin	Tetrahydrocurcumin (Tetrahydrodiferuloylmethane, Tetrahydro Curcumin), a major metabolite of curcumin, possesses strong antioxidant and cardioprotective properties.
S5675	Yamogenin	Yamogenin, a sapogenin found in fenugreek, inhibits lipid accumulation through the suppression of gene expression in fatty acid synthesis in hepatocytes.
S5373	Pseudolaric Acid B	Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
S5676	Zearalenone	Zearalenone (F2 toxin, RAL) is a non-steroidal estrogenic mycotoxin that acts by binding the estrogen receptor (ER).
S5678	trans-Zeatin-riboside	Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process, and activate gene expression and metabolic activity.
S5705	Raceanisodamine	Raceanisodamine (7β-Hydroxyhyoscyamine) is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.
S3843	Madecassoside	Madecassoside (Asiaticoside A)是积雪草草药的主要活性三萜烯成分，积雪草是一种传统中药，用于治疗创伤修复和疤痕管理。
S5560	Midecamycin	Midecamycin (Espinomycin A, Medecamycin A1, Platenomycin B1, Rubimycin, Turimycin P3) is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S5559	Tetrahydropalmatine	Tetrahydropalmatine, a plant alkaloid used as an ingredient in dietary supplement products, is a potent and selective D1 receptor antagonist.
S5466	Saikosaponin A	Saikosaponin A is a triterpene saponin derived from the medicinal plant, Bupleurum chinensis DC. (Umbelliferae). It has a variety of pharmacological benefits, including anti-inﬂammatory, immunomodulatory, and anti-bacterial activities.
S5622	Prohydrojasmon	Prohydrojasmon is a newly launched plant growth regulator, which has jasmonic acid activity.
S5493	Atropine sulfate	Atropine Sulfate (Sulfatropinol, Atropette, Tropintran) is the sulfate salt of atropine, which is a natural alkaloid anticholinergic agent and has potent antimuscarinic effects.
S5102	Stachyose	Stachyose is a natural sugar found in many foods like beans and vegetables.
S4545	Warfarin	Warfarin (Athrombine K, Coumadin, Coumafene, WARF 42, Zoocoumarin) 是一种广泛使用的抗凝剂，用来抗血栓形成和血栓栓塞、阻止血管中血凝块的形成和迁移。
S3991	Ketoisophorone	Ketoisophorone (4-Oxoisophorone), also known as 4-Oxoisophorone, is the major component of saffron spice.
S3992	D-(+)-Trehalose dihydrate	Trehalose是一种非还原糖，提高植物和动物对脱水的抵抗力。
S3993	Ethyl Vanillate	Ethyl vanillin (Bourbonal, Ethylprotal) 是一种香草醛类似物，可用作调味剂和杀真菌剂，具有很强的抗氧化活性。Ethyl Vanillate 抑制 17β-HSD2 的IC50值为1.3 µM。
S3994	Methyl Cholate	Methyl Cholate (Cholic acid methyl ester) is methyl ester form of Cholic acid that is a primary bile acid mainly produced by the liver.
S3995	Guaiazulene	Guaiazulene (Azulon, Vetivazulen) 是一种双环倍半萜烯，是一些精油的组成成分。
S3996	Thioctic acid	Thioctic acid (DL-α-Lipoic acid)是环状二硫抗氧化剂，可与其还原性二硫酚形式相互转换。
S3998	(+)-α-Lipoic acid	(+)-α-Lipoic acid ((R)-(+)-α-Lipoic acid, α-Lipoic acid, Alpha-Lipoic acid)是thioctic acid的生理形式之一，是一种强效的抗氧化剂，可减轻糖尿病神经性症状。它比其外消旋体具有更优越的抗氧化性。R(+)-α-lipoic acid 是线粒体酶复合物的必要辅助因子。R(+)-α-lipoic acid 抑制 NF-κB 依赖性HIV-1 LTR 活化。
S5157	Thymol	Thymol (2-isopropyl-5-methylphenol, IPMP), a naturally occurring monocyclic phenolic compound derived from Thymus vulgaris (Lamiaceae), has been reported to exhibit anti-inflammatory property in vivo and vitro.
S5161	1-Octacosanol	1-Octacosanol (n-Octacosanol, Octacosyl alcohol, Octanosol, Montanyl alcohol, Cluytyl alcohol) is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. It is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties.
S5172	1-Triacontanol	1-Triacontanol (n-Triacontanol, Melissyl alcohol, Myricyl alcohol) is a fatty alcohol found in plant cuticle waxes and in beeswax. It is a growth stimulant for many plants, most notably roses.
S5143	Citropten	Citropten (5,7-Dimethoxycoumarin, Citroptene, Limettin, Limetin) is a natural organic compound which belongs to coumarins and derivatives class.
S5142	D-(+)-Melezitose	Melezitose (D-Melezitose, (+)-Melezitose, D-melicitose, (+)-melicitose, melicitose) is a nonreducing trisaccharide sugar that is produced by many plant sap eating insects.
S5141	Pyrithioxin	Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
S5132	Casanthranol	Casanthranol is a purified mixture of te antranol glycosides derived from Cascara sagrada.
S5128	Orsellinic acid ethyl ester	Orsellinic acid (Ethyl Orsellinate), a phenolic acid, is of importance in the biochemistry of lichens, from which it can be extracted.
S4954	Djenkolic Acid	Djenkolic Acid (Jengkolic acid, Djenkolate, S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans. It is toxic to humans, often causing kidney failure.
S4827	Manganese chloride	Manganese chloride在自然界中以矿物质形式存在。它常被用作其他锰化合物的合成前体。
S4969	Tropine	Tropine (Pseudotropine, 3alpha-Tropanol) 是一种天然存在的莨菪烷生物碱，是多种具有生物活性的生物碱合成的中间体，这些生物碱大多具有有效的神经学作用。
S4940	Maltol	Maltol (Larixinic acid, Palatone, Veltol)是一种天然有机化合物，可作为香味增强剂和调味剂。
S4859	TriacetonaMine	TriacetonaMine (Tempidon, Tmpone, Odoratine, Vincubine)，作为一种哌啶酮（Piperidinone），是一种具有极弱酸性的化合物，存在于绿色植物和茶中。
S4863	4-Hydroxyphenylacetic acid	4-Hydroxyphenylacetic acid (p-Hydroxyphenylacetic acid, parahydroxy phenylacetate) 是一种存在于橄榄油和啤酒中的化合物，作为一种化学中间体用于合成阿替洛尔（atenolol）和3,4-dihydroxyphenylacetic acid。
S4864	2-Furoic acid	2-Furoic acid (2-Furancarboxylic acid, Pyromucic acid, 2-Carboxyfuran, α-furancarboxylic acid, α-furoic acid)是一种广泛用于食品生产的有机化合物，作为防腐剂和增味剂。
S4949	Nonanoic acid	Nonanoic acid (Pelargonic acid, Nonoic acid) 是一种天然存在于蔬菜和动物脂肪中的脂肪酸。
S4862	Squalene	Squalene (Spinacene, Supraene, trans-Squalene)，自然存在于植物、动物和人体中，是一种添加在疫苗中佐剂，用于增强免疫反应。
S4943	Isovanillin	Isovanillin (5-Formylguaiacol, 3-Hydroxy-p-anisaldehyde, 3-Hydroxy-4-methoxybenzaldehyde)是醛脱氢酶（aldehyde oxidase）的可逆性抑制剂。它被广泛用作药物中间体，应用于食物和饮料行业、化学合成香料和化学分析领域。
S4951	L-Threonine	L-Threonine是一种必需氨基酸，处于活化形式。它对于胶原蛋白、弹性蛋白和牙釉质的形成十分重要，连同天冬氨酸、甲硫氨酸一起发挥滋养肝脏、抗脂肪肝的作用。
S4952	Fumaric acid	Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) 是三羧酸循环中的中间产物。细胞利用三羧酸循环从食物中产生能量（ATP形式）。Fumaric acid还是尿素循环的产物。
S4953	Usnic acid	Usnic acid (Usniacin)是存在于lichen（地衣）中的一种呋喃二酮，广泛应用于化妆品、除臭剂、牙膏和药用霜、中草药成品中。它具有抗病毒、抗原生动物、抗增殖和抗炎、止痛活性。Usnic acid 可通过抑制VEGFR2介导的 AKT 和 ERK1/2 信号通路来抑制乳腺肿瘤血管生成和生长。
S4960	Jasmone	Jasmone是一种天然有机化合物，分离自茉莉花油的挥发成分。
S4957	Linalool	Linalool (Phantol)是一些芳香剂中的香精油的主要成分。它是NMDA receptors的竞争性拮抗剂。
S4941	Farnesol	Farnesol是一种天然的倍半萜烯醇，有效地治疗抗代谢障碍、具有抗炎、抗氧化、抗肿瘤和抗菌活性。
S5122	Abietic Acid	Abietic acid (Sylvic acid, Abietate, Rosin Acid), an abietane diterpenoid, inhibited soybean 5-lipoxygenase with an IC50 of 29.5 ± 1.29 μM.
S5126	Aleuritic Acid	Aleuritic Acid (Aleuritolic acid, 9,10,16-trihydroxy-palmitic acid), a major constituent acid of lac resin (shellac), is isolated from the resin and mainly used in the perfumery industry as a starting material for the preparation of "musk" aroma compounds as well as medicinal and bioactive compounds.
S5134	D(-)-Arabinose	D-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast.
S5135	Hydroferulic acid	Hydroferulic acid (Dihydroferulic acid, Dihydroconiferylic acid) is classified as a member of the phenylpropanoic acids. It is slightly soluble in water and acidic.
S4828	Sodium carbonate	Sodium Carbonate (Disodium carbonate, Soda Ash, Carbonic acid disodium salt) 是碳酸的二钠盐形式，具有碱化特性。
S4939	cis-Aconitic acid	Cis-Aconitic acid (cis-aconitate, Achilleic acid, Citridinic acid, Equisetic acid, Pyrocitric acid)是三羧酸循环中的中间产物，由柠檬酸脱水形成。
S4946	2,3-Dihydroxybenzoic acid	2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) 是一种天然酚类，存在于西印度醋栗和水生蕨类Salvinia molesta，也是人体中阿司匹林的代谢产物。它是一种潜在的铁螯合药物，具有抗菌特性。
S4962	Agmatine sulfate	Agmatine sulfate是精氨酸的活性代谢产物，能够提高一氧化氮水平、减少血糖水平并提高生长激素水平。
S4893	Cytosine	Cytosine (4-Amino-2-hydroxypyrimidine, Cytosinimine)是存在于DNA和RNA中的四种主要碱基中的一种，被细胞用于储存和传输遗传信息。
S4958	Glycocholic acid	Glycocholic acid (Cholylglycine, Glycocholate) 是一种天然的次级胆汁酸，参与脂肪的乳化。
S4820	Diastase	Diastase是天然存在的、可催化淀粉分解为麦芽糖的酶。
S4959	Skatole	Skatole (3-methylindole, Scatole)是一种具有轻度毒性的白色结晶有机化合物，天然存在于排泄物中，具有相当广泛的抑菌作用。
S4963	Purpurin	Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。
S4966	4-Methylesculetin	4-methylesculetin是香豆素衍生物，具有强大的抗氧化和抗炎活性。4-Methylesculetin 可抑制 myeloperoxidase (MPO) 活性并降低 IL-6 水平。
S4968	Cholesteryl Acetate	Cholesteryl Acetate (Acebrochol, Cholesterol, Cholesterin)，天然存在于不同液体、器官和食物中，是一种正常的人类胆甾醇酯。
S4830	Maltose	Maltose (Maltobiose, Malt Sugar, Beta-Maltose, D-Maltose)，一种能够提供能量的非必需营养物，是糖原和淀粉的肠道消化过程中的中间产物，存在于发芽的谷物或其他植物、蔬菜中。
S5160	4-Methoxysalicylic acid	4-Methoxysalicylic acid (2-Hydroxy-p-anisic Acid), an arabinose derivative, is used in the synthesis of 1,3,4-oxadiazole derivatives.
S5162	Isovanillic acid	Isovanillic acid (Acide isovanillique, 3-Hydroxyanisic acid, 3-Hydroxy-p-anisic acid), a metabolite of isovanillin, is a selective inhibitor of aldehyde oxidase.
S5163	7-Methoxycoumarin	7-Methoxycoumarin (Herniarine), also known as Herniarin, is a methoxy derivative of coumarin and substrate for dealkylase. It has been used in the synthesis of anti-first-pass effect compounds and detergents.
S3950	Maltitol	Maltitol (Maltisorb, 4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute. It is especially useful in the production of sweets, including sugarless hard candies, chewing gum, chocolates.
S3951	Tannic acid	Tannic acid (Gallotannic acid) 是一种多酚化合物，是一种具有抗血管生成，抗炎和抗肿瘤活性的 CXCL12/CXCR4 的抑制剂。
S5113	Propyl gallate	Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
S4799	Indole-3-acetic acid	Indole-3-acetic acid (indolylacetic acid, 1H-Indole-3-acetic acid, indoleacetic acid, heteroauxin, IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.
S5167	Benzyl cinnamate	Benzyl cinnamate (Cinnamein, Benzylcinnamoate, Benzyl 3-phenylpropenoate, Cinnamic acid benzyl ester), a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative.
S5168	Anthraquinone	Anthraquinones (Anthradione, anthracenedione, dioxoanthracene) are the main active constituents in herbs often used to relieve constipation.
S5174	Kojic acid	Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
S5175	(-)-Ambroxide	Ambroxide, a naturally occurring terpenoid, is one of the key constituents responsible for the odor of ambergris and an autoxidation product of ambrein.
S4762	2,4-Dihydroxyacetophenone	2,4-Dihydroxyacetophenone (Resacetophenone, 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron.
S4765	Syringaldehyde	Syringaldehyde (Syringic aldehyde) is an organic compound that occurs naturally in trace amounts. It possesses worthy bioactive properties and is, therefore, used in pharmaceuticals, food, cosmetics, textiles, pulp and paper industries, and even in biological control applications.
S4768	Melibiose	Melibiose (Galalpha1-6Glcbeta) is a nondigestible disaccharide that consists of one galactose and one glucose moiety in an alpha (1-6) glycosidic linkage.
S5110	Safflower Yellow	Safflower Yellow (Safflor Yellow, SY), the main active constituent of the traditional Chinese medicine Safflower, is known as a neuroprotective agent that indirectly attenuates neuroinflammation.
S5116	Bilibubin	Bilibubin (Bilirubin) is a tetrapyrrole and a breakdown product of heme catabolism that acts as a physiological, chain-breaking antioxidant.
S4769	L-5-Hydroxytryptophan	5-Hydroxytryptophan (5-HTP, L-oxitriptan), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
S4770	Creatine phosphate disodium salt	Phosphocreatine, also known as creatine phosphate (CP) or PCr (Pcr), is a phosphorylated creatine molecule that serves as a rapidly mobilizable reserve of high-energy phosphates in skeletal muscle and the brain to recycle adenosine triphosphate, the energy currency of the cell.
S4771	β-thujaplicin	β-Thujaplicin (β-TH, Hinokitiol, 4-Isopropyltropolone) is a toxic tropolone derivative present in the heartwood of western red cedar (Thuja plicata) and is used as a preservative and antimicrobial additive in a number of commercial goods. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
S4772	alpha-Asarone	Alpha (α)-asarone (trans-Asarone) is one of the main pharmacologically active compounds present in Acorus calamus Linn (Acoraceae), Acorus tatarinowii Schott (Acoraceae), and Acorus gramineus Solander. It has anticonvulsant, neuroprotective, anxiolytic and nootropic effects.
S4773	Adrenosterone	Adrenosterone (Reichstein's substance G, 11-ketoandrostenedione, 11-oxoandrostenedione) is endogenous steroid hormone that has been promoted as a dietary supplement capable of reducing body fat and increasing muscle mass.
S4774	Xanthurenic Acid	Xanthurenic acid (xanthurenate, 8-Hydroxykynurenic acid, 4,8-Dihydroxyquinaldic acid), a molecule arising from tryptophan metabolism by transamination of 3-hydroxykynurenine, activates mGlu2/3 Metabotropic glutamate receptors (mGlu2 and mGlu3).
S4776	Harmaline	Harmaline, a natural occurrence β-carboline alkaloid, is a central nervous system stimulant and an acetylcholinesterase (AChR) inhibitor; also inhibits histamine N-methyltransferase.
S4777	Plumbagin	Plumbagin (Plumbagine, Plumbaein, Plumbagone), a quinoid constituent isolated from the root of the medicinal plant Plumbago zeylanica L, exerts anticancer and antiproliferative activities in animal models and in cell culture.
S3896	(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine	(1R,2R)-trans-N-Boc-1,2-cyclohexanediamine is an intermediate in organic synthesis.
S3897	(-)-Arctigenin	(-)-Arctigenin, a lignan found in certain plants of the Asteraceae, exerts biological activities including anti-inflammatory, antiviral and anticancer.
S4781	Xanthoxyline	Xanthoxylin (Brevifolin), isolated from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree), is a cytotoxic and fungicidal compound with the characteristics of a typical phytoalexin.
S3899	Hederagenin	Hederagenin (Caulosapogenin, Hederagenol, Hederagenic acid, Astrantiagenin E) is a highly water insoluble triterpenoid compound that can be found in various plants including Hedera helix and Chenopodium quinoa. It exhibits a variety of biological activities, including potent antitumor properties both in vitro and in vivo. Hederagenin inhibits LPS-stimulated expression of iNOS, COX-2, and NF-κB.
S3900	Betulonic acid	Betulonic acid (Liquidambaric acid), derived from betulinol, a pentacyclic styrene, has shown a highly specific anti-prostate cancer activity in in vitro cell cultures.
S4783	Benzyl isothiocyanate	Benzyl isothiocyanate (BITC, Benzoylthiocarbimide, Isothiocyanic Acid Benzoyl Ester) is an isothiocyanate originally found in cruciferous vegetables that exhibits immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiogenic, anti-metastatic, anticancer chemotherapeutic, and chemopreventive activities.
S3902	Ursonic acid	Ursonic acid (Prunol, Malol, beta-Ursolic acid, NSC4060, CCRIS 7123, TOS-BB-0966), present in many plants, is a pentacyclic triterpenoid that can be used as a cosmetics additive and serve as a starting material for synthesis of more potent bioactive derivatives, such as experimental antitumor agents.
S4784	Phloracetophenone	Phloracetophenone, or 2,4,6-trihydroxyacetophenone (THA), the aglycone component of phloracetophenone glucoside, is a naturally occurring compound obtained from the rhizome of Curcuma comosa (Family Zingiberaceae).
S3903	Lycorine	Lycorine (Galanthidine, Amarylline, Narcissine, Licorine, Belamarine) is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.
S3904	Isoimperatorin	Isoimperatorin, a natural furanocoumarin that can be isolated from a variety of plant parts, has analgesic, antimicrobial, vascular relaxing and anticancer activities.
S3905	Iso-Steviol	Isosteviol (ISV) is mainly obtained by acid hydrolysis of stevioside, the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni). It possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant effects.
S4788	L-α-Phosphatidylcholine	L-α-phosphatidylcholine, a surfactant and a constituent of the liposomal carrier system, has shown hepatoprotection in the various hepatotoxicity model.
S4791	S-allyl-L-cysteine	S-Allyl cysteine (SAC, S-Allylcysteine), a natural constituent of fresh garlic, has antioxidant and anticancer properties in animals.
S4793	Cedryl acetate	Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
S4809	3-Indolepropionic acid	3-Indolepropionic acid (IPA, indole-3-propionic acid), a gut microbial metabolite, is a potent neuroprotective antioxidant and plant auxin.
S5124	DL-Citrulline	L-Citrulline (Citrulline, Cit) is a naturally occurring nonessential amino acid which is the key intermediate in the urea cycle.
S5136	Calcium folinate	Calcium folinate (Leucovorin calcium, Folinic acid calcium salt, Wellcovorin) is a metabolically active, reduced form of folic acid that is rapidly absorbed and extensively metabolized in the liver to other folic acid derivatives.
S3980	Pyridoxine	Pyridoxine (Pyridoxol, Vitamin B6, Gravidox), also known as vitamin B6, is a form of vitamin B6 found commonly in food and used as dietary supplement. It is a cofactor for both glutamic acid decarboxylase and GABA transaminase.
S3967	Flavone	Flavone (2-Phenylchromone, 2-Phenyl-4-chromone, 2-Phenyl-4-benzopyron), a class of flavonoids, mainly found in spices and red or purple plant foods with antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders etc.
S3975	Protocatechuic acid	Protocatechuic acid (PCA, 3,4-Dihydroxybenzoic acid, Protocatechuate), a dihydroxybenzoic acid, is a type of widely distributed naturally occurring phenolic acid.
S3976	Acetylvanillin	Acetylvanillin (Acetovanillin, Vanillin acetate, 4-Acetoxy-3-methoxybenzaldehyde, 4-Formyl-2-methoxyphenyl acetate) is found in pulses and is a flavouring material.
S3977	(-)-Borneol	(-)-Borneol (L-Borneol), one of enantiomers of borneol, has a camphoraceous and evident woody odor.
S4821	Glycine	Glycine (2-Aminoacetic acid, Aminoacetic acid, Glycocoll) is a non-essential, non-polar, non-optical, glucogenic amino acid that is primarily found in gelatin and silk fibroin. It is involved in the body's production of DNA, phospholipids and collagen, and in release of energy.
S4826	Aluminium hydroxide	Aluminium hydroxide (Aluminic), found in nature as the mineral gibbsite, is amphoteric (i.e., it has both basic and acidic properties). It is used to treat symptoms of increased stomach acid, such as heartburn, upset stomach, sour stomach, or acid indigestion; also reduce phosphate levels in people with certain kidney conditions.
S3986	L-Arabinose	L-Arabinose (L-Ara) 是一种植物糖，不存在于动物中。它是细胞壁的成分之一，可能用于天然药物的合成。
S3987	L-Tryptophan	L-tryprophan是必需氨基酸，是一种天然的情绪调节剂，为婴幼儿正常生长、成人氮平衡所必需。
S3989	L-Histidine	L-Histidine (Glyoxaline-5-alanine) 是一种α-氨基酸，是人类生长和组织修复所必需，被用于蛋白质的生物合成。
S3990	Trans-Anethole	Trans-anethole (4-Propenylanisole)是苯丙烯衍生物，存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。
S4972	Choline Glycerophosphate	Choline Glycerophosphate (Glycerophosphorylcholine) 是胆碱衍生物，是胞浆中两种主要的胆碱储存形式之一。
S4981	Cyclogalegenol	Cyclogalegenol (Astramembrangenin, Cyclosieversigenin) 是astragaloside A的糖苷配基衍生物，存在于多种紫云英属物种中，可能可激活端粒酶。
S4982	2,2':5',2''-Terthiophene	2,2':5',2''-Terthiophene是来源于金盏花的天然产物，具有受紫外线增强的抗菌活性。
S4983	Sorbic acid	Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
S2323	Methyl-Hesperidin	Methyl-Hesperidin 是一种在柑橘类水果中广泛存在的黄酮苷（黄酮）（C28H34O15），其苷元形式被称为橙皮素。
S5090	4-Isopropylbenzyl Alcohol	4-Isopropylbenzyl Alcohol (Cumic alcohol, Cuminyl alcohol, Cuminic alcohol)，分离自赤桉，是一种具有杀虫作用的化合物。
S5091	Geranyl acetate	Geranyl acetate (Geraniol acetate, Geranyl ethanoate) 是一种天然有机化合物，主要用作面霜和肥皂的香料或是调味成分。
S5089	4-Isopropylbenzaldehyde	4-Isopropylbenzaldehyde (Cuminaldehyde, Cuminic aldehyde, Cuminal)，一种天然有机化合物，是一种药物中间体，具有宜人的香味，有助于香精油中的香气。
S5086	p-Anisaldehyde	p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde)，茴芹种子提取物，具有抗真菌活性，对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。
S5220	D-Pantethine	Pantethine (Bis-pantethine, Pantetina, Pantomin, Pantosin)是一种天然产物，在体内由泛酸（维生素B5）通过半胱胺的加入合成，被用作一种食品添加剂，降低血胆固醇和三酸甘油脂。
S3982	Batyl alcohol	Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
S5156	4-Methoxysalicylaldehyde	4-Methoxysalicylaldehyde (2-Hydroxy-4-methoxybenzaldehyde), a naturally occurring product, has a range of industrial applications in the preparation of organic compounds, drugs and therapeutic agents.
S5154	Tetrahydropiperine	Tetrahydropiperine (Cosmoperine), derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.
S5155	Raffinose	Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.
S5226	L-carnosine	L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.
S3970	Vindoline	Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly.
S5570	Arachidic acid	Arachidic acid (eicosanoic acid, Icosanoic Acid) is a natural saturated fatty acid used for the production of detergents, photographic materials and lubricants.
S3971	Fusidine	Fusidine (Fusidic Acid), isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S3972	Lobeline hydrochloride	Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine. It is also a VMAT2 ligand and an antagonist of μ-opioid receptors.
S5562	2-Hydroxybenzyl alcohol	2-Hydroxybenzyl alcohol (Salicyl alcohol, Salicain, Diathesin, Saligenin, Saligenol, o-Methylolphenol, α,2-Toluenediol), which can be found in a number of food items such as red huckleberry, rye, jerusalem artichoke, and ceylon cinnamon, is precursor of salicylic acid and is formed from salicin by enzymatic hydrolysis by Salicyl-alcohol beta-D-glucosyltransferase or by acid hydrolysis.
S5335	Corey Lactone Diol	Corey Lactone Diol is a pharmaceutical intermediate.
S5336	Hecogenin	Hecogenin (Hocogenin), a steroid saponin isolated from Agave sisalana, is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM.
S5338	L(-)-Sorbose	L(-)-Sorbose (L(-)-Sorbopyranose) is a ketose sugar that is commonly used in the commercial synthesis of ascorbic acid.
S5343	Vanillic acid	Vanillic acid (4-hydroxy-3-methoxybenzoic acid) is a flavoring agent which is also an intermediate in the production of vanillin from ferulic acid. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.
S5337	Rauwolscine hydrochloride	Rauwolscine hydrochloride (Isoyohimbine, α-Yohimbine, corynanthidine) is the hydrochloride salt form of Rauwolscine, a specific and potent α2 antagonist with Ki of 12 nM.
S5342	Dihydrojasmone	Dihydrojasmone, belonging to the family of ketones, is an aroma compound for perfumery uses.
S5339	4-Allylanisole	4-Allylanisole (Estragole, p-Allylanisole, Methyl chavicol) is a natural organic compound that is a component of various trees and plants. It is used in the preparation of fragrances.
S3785	Notoginsenoside R1	Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.
S5345	Nerolidol	Nerolidol (Peruviol) is a naturally occurring sesquiterpene found in the essential oils of many types of plants and flowers. It has diverse range of pharmacological and biological activities including antioxidant, anti-microbial, anti-biofilm, anti-parasitic, insecticidal, anti-ulcer, skin penetration enhancer, anti-tumor, anti-nociceptive and anti-inflammatory properties.
S5347	2-Phenylethylamine	2-Phenylethylamine (β-Phenylethylamine, benzeneethanamine, β-aminoethylbenzene) is a natural monoamine alkaloid that functions as a monoaminergic neuromodulator or a neurotransmitter in the human central nervous system.
S5348	Pherocon (4-(4-Acetoxyphenyl)-2-butanone)	Pherocon (4-(4-Acetoxyphenyl)-2-butanone, 4-(p-Acetoxyphenyl)-2-butanone, 4--(3-Oxobutyl)phenyl acetate) is a standard melon fly attractant for detection programs.
S5440	Berberine Sulfate	Berberine sulfate (Umbellatine), an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
S3772	5-Hydroxymethylfurfural	5-Hydroxymethylfurfural (5-HMF) is an important bio-sourced intermediate, formed from carbohydrates such as glucose or fructose and used for production of fuels and chemical intermediates.
S3792	Guggulsterone E&Z	Guggulsterone is one of the active constituent of Commiphora mukul. It occurs in two isomeric forms, namely Z-GS and E-GS. Guggulsterone act as antagonist ligands for the bile acid receptor, farnesoid X receptor, and as active ingredients responsible for the hypolipidemic activity.
S5407	Squalane	Squalane (Perhydrosqualene, Dodecahydrosqualene) is a naturally occuring lipid in both plants and animals. It is usually used as an emollient and moisturizer in cosmetics manufacturing.
S3805	Stevioside	Stevioside is a natural sweetener extracted from leaves of Stevia rebaudiana (Bertoni) Bertoni.
S5583	Cinnamyl acetate	Cinnamyl acetate (3-Phenylallyl acetate) is a naturally occuring compound used as a flavouring agent.
S5584	Citronellol	Citronellol (Dihydrogeraniol, (±)-β-Citronellol), a constituent of rose and geranium oils, is used in perfumes and insect repellents. Citronellol can cause necrotic apoptosis of NCI-H1299 cells by up-regulating TNF-α, RIP1 / RIP3 activities, and down-regulating caspase-3 / caspase-8 activities. Citronellol also results in a biphasic increase in ROS production at 1 h and at 12 h in NCI-H1299 cells.
S5419	1,4-Cineole	1,4-Cineole (Isocineole) is a flavor constituent of Citrus aurantifolia and Piper cubeba.
S3894	Cycloastragenol	Cycloastragenol (CAG, TA-65, Cyclogalegigenin, Astramembrangenin) is a saponin comprising a group of oil glucosides naturally present in a number of plants. It is a potent telomerase activator in neuronal cells.
S5380	7-Hydroxyflavone	7-Hydroxyflavone is a potent inhibitor of CYP1A1 with a Ki value of 0.015 μM and exhibits 6-fold greater selectivity for CYP1A1 over CYP1A2. It also has excellent antioxidant properties and great potential to be applied as medicines.
S3895	Sophoridine	Sophoridine (5-Epidihydrosophocarpine, Dihydro-5-episophocarpine), a natural product obtained from medicinal plants, has a variety of pharmacological effects, including anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems.
S5381	Behenic Acid	Behenic Acid (docosanoic acid) is a long-chain saturated fatty acid that exists naturally as a triglyceride in canola. It act as a lubricant that helps restore the skin's natural oils and improve overall levels of hydration.
S3849	D-Galactose	D-Galactose (D-Galactopyranose, D-(+)-Galactose) is an aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.
S3850	Glucosamine sulfate	Glucosamine sulfate (D-Glucosaminesulfate, D-Glucosamine sulphate) is a dietary supplement commonly used in the treatment of osteoarthritis. It is a type of glycosaminoglycan, which is a naturally occurring major component of joint cartilage and joint fluid.
S3851	Camphor	Camphor (2-Bornanone, Bornan-2-one, 2-Camphanone, Formosa) is a bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora and used topically as a skin antipruritic and as an anti-infective agent.
S3852	L-Theanine	L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
S3854	Tetrahydropalmatine hydrochloride	Tetrahydropalmatine (THP, Gindarine, 1-Tetrahydropalmitine) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda. It is a potent muscle relaxant.
S3855	Ethyl ferulate	Ethyl ferulate (Ferulic acid ethyl ester) is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferative activities.
S3856	Allantoin	Allantoin (Glyoxyldiureide, 5-Ureidohydantoin), produced from uric acid, is a major metabolic intermediate in most organisms including animals, plants and bacteria.
S3857	4-Hydroxybenzyl alcohol	4-hydroxybenzyl alcohol (P-Methylolphenol, 4-Methylolphenol), an important phenolic constituent of Gastrodia elata Blume (GEB), has been shown to have many beneficial effects in different animal models of neurological disorders, such as, headaches, convulsive behavior, dizziness, and vertigo.
S3858	Lawsone	Lawsone (Hennotannic acid, 2-hydroxy-1,4-naphthoquinone) is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
S3859	Vanillyl Alcohol	Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol, Vanillin alcohol, Vanillic alcohol, 3-Methoxy-4-hydroxybenzyl alcohol), derived from vanillin, is used to flavor food.
S5618	Hippuric acid	Hippuric Acid (2-Benzamidoacetic acid, Benzoylglycine) is an acyl glycine produced by the conjugation of benzoic acid and glycine, found as a normal component in urine as a metabolite of aromatic compounds from food.
S3862	Gallic acid trimethyl ether	Gallic acid trimethyl ether (Eudesmic acid, Tri-O-methylgallic acid, Benzoic acid, 3,4,5-Trimethoxybenzoic acid) is an O-methylated trihydroxybenzoic acid that is found in olive.
S3864	Dulcitol	Dulcitol (Galactitol, D-Galactitol, Dulcose) is a naturally occurring product of plants obtained following reduction of galactose.
S3865	Taurochenodeoxycholic acid	Taurochenodeoxycholic acid (Taurochenodeoxycholic acid (Taurochenodeoxycholate, TCDCA, Chenodeoxycholyltaurine)), a bile acid formed in the liver of most species, is used as a cholagogue and choleretic.
S3866	Galanthamine	Galanthamine (Galantamine, Nivalin, Razadyne, Razadyne ER, Reminyl, Lycoremine) is a phenanthrene alkaloid and a reversible, competitive acetylcholinesterase inhibitor with IC50 of 0.35 μM, exhibits 50-fold selectivity against butyryl-cholinesterase. It is studied as a treatment for Alzheimer's disease and other central nervous system disorders.
S3868	Harmine	Harmine (Telepathine) is an alkaloid of the β-carboline family that regulates PPARγ expression through inhibition of the Wnt signaling pathway. It also selectively binds to MAO-A and reversibly inhibits monoamine oxidase A (MAO-A) but not the variant MAO-B.
S3870	D-Pinitol	D-pinitol (Methylinositol, Pinitol, 3-O-Methyl-D-chiro-inositol, D-(+)-Pinitol, Inzitol) is a naturally occurring compound derived from soy and has significant pharmacological activitites such as inhibition of the T-helpercell-1 response, antiviral, larvicidal, antiinflammatory, antihyperlipidemic, cardioprotective, inhibition of ovalbumin-induced airway inflammation and antioxidant.
S3872	Guaiacol	Guaiacol (O-methoxyphenol, 2-hydroxyanisole, O-methylcatechol) is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a precursor to various flavorants, such as eugenoland vanillin. Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.
S5461	Cimicifugoside	Cimicifugoside is a triterpenoid originating from the rhizomes of Cimicifuga simplex, and acts to inhibit the subcellular transport of nucleosides.
S5454	Saikosaponin D	Saikosaponin D, a calcium mobilizing agent (SERCA inhibitor), is a type of Saponin derivative, which is a component extracted from Bupleurum falactum. Saikosaponin D has anti-cancer activities.
S3981	Sinapinic Acid	Sinapinic acid (Sinapic acid) 是一种天然的小羟基肉桂酸，属于苯基丙烷类，通常在MALDI质谱中用作基质。Sinapinic acid (Sinapic acid) 作为 HDAC 的抑制剂，IC50为2.27 mM，并且还抑制 ACE-1 活性。
S3983	Caryophyllene oxide	Caryophyllene oxide是存在于多种植物精油中的氧化萜类化合物，在食物、药物和化妆品中被用作防腐剂，具有消炎、抗癌和增强皮肤渗透活性。
S3984	Nordihydroguaiaretic acid (NDGA)	Nordihydroguaiaretic acid (NDGA)是一种天然存在的酚类防老剂。它是公认的脂肪氧合酶 lipoxygenase抑制剂，具有抗氧化、清除自由基的活性。Nordihydroguaiaretic acid (NDGA) 是一种具有细胞毒性的 insulin-like growth factor-I receptor (IGF-1R)/HER2 的抑制剂，可诱导细胞凋亡。Nordihydroguaiaretic acid (NDGA) 可抑制 p300 并激活自噬。Nordihydroguaiaretic acid (NDGA) 可保护细胞免于铁死亡。
S5105	Proanthocyanidins	Proanthocyanidins (PAs), also known as condensed tannins, are a class of polyphenols found in a variety of plants. They are very powerful antioxidants that remove harmful free oxygen radicals from cells.
S5148	2-Methylenebutyrolactone	2-Methylenebutyrolactone (Tulipalin A, MBL, α-methylene-γ-butyrolactone)，也被称作α-methylene-γ-butyrolactone (MBL) 或Tulipalin A，是一种倍半萜内酯，被认为是最常见乙烯基单体甲基丙烯酸甲酯（MMA）的环状类似物。
S5119	Olivetol	Olivetol (5-Pentylresorcinol, 5-n-Amylresorcinol) is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.
S5150	Phytosterols	Phytosterols，也被称作植物甾醇或醇酯，存在于植物中，结构类似于人体中胆固醇。
S5151	Gypenoside	Gypenoside (GP)是绞股蓝中的主要有效成分，具有消炎和抗氧化活性。
S3956	Tetramethylpyrazine	Tetramethylpyrazine (ligustrazine, TMP) is a natural compound isolated from Chinese herbal medicine Ligusticum wallichii (Chuan Xiong) with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S3957	Gamma-Oryzanol	Gamma-oryzanol (GO), a nutriactive phytochemical naturally occurring in crude rice bran oil, is an antioxidant compound used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.
S3959	(+)-Borneol	(+)-Borneol is one of enantiomers of borneol which is a valuable medical material, senior aromatic spice, and chemical material and has been used in food and also folk medicine.
S3962	Dihydroactinidiolide	Dihydroactinidiolide is known to be a bioactive molecule in animals. It is a component of pheromones in insects, such as red fire ants and in mammals such as the Cat and the Red Fox.
S3963	DL-Glutamine	DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
S3968	Histamine	Histamine, an organic nitrogenous compound, is involved in local immune responses regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus. It is a potent H1 and H2 receptor agonist.
S5120	Elemicin	Elemicin (3,4,5-trimethoxyallylbenzene) is a constituent of the oleoresin and the essential oil of Canarium luzonicum.
S5121	Phytol	Phytol (Trans-Phytol), a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, shows antinociceptive and antioxidant activities as well as anti-inflammatory and antiallergic effects. It is a specific activator of PPARα.
S5139	Methyl Dihydrojasmonate	Methyl dihydrojasmonate (Hedione, Kharismal) is a flavouring ingredien with the smell vaguely similar to jasmin.
S5138	Citral	Citral (Geranialdehyde) is an α,β-unsaturated aldehyde present in the oils of several plants. It is an aroma compound used in perfumery for its citrus effect and is also used as a flavor and for fortifying lemon oil.
S4754	Betulin	Betulin (BE, betulinol, betuline, betulinic alcohol), also known as betulinol, betuline, or betulinic alcohol, is a pentacyclic lupane-type triterpenoid naturally distributed in many plants and displays a broad spectrum of biological and pharmacological properties such as anticancer and chemopreventive activity.
S3955	Uric Acid	Uric Acid (2,6,8-Trioxypurine, 2,6,8-Trihydroxypurine, 2,6,8-Trioxopurine), a normal component of urine, is a product of the metabolic breakdown of purine nucleotides.
S4766	Gibberellic acid	Gibberellic acid (Gibberellin, Gibberellin A3, GA3, GA), a plant hormone stimulating plant growth and development, is a tetracyclic di-terpenoid compound.
S3948	Spermine	Spermine (4,9-Diaza-1,12-dodecanediamine) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria.
S2283	Cinchonine(LA40221)	Cinchonine (LA40221)是一种生物碱，是cinchonidine的立体异构体和假对映异构体。.
S3654	Tauroursodeoxycholic Acid (TUDCA)	Tauroursodeoxycholic acid (TUDCA)是乌索脱氧胆酸的牛磺酸共轭产物，在多种神经退行性疾病，如阿尔茨海默病、帕金森疾病和亨廷顿疾病中，可作为线粒体稳定剂和抗凋亡试剂。
S3752	isoleucine	Isoleucine (Ile) is a non-polar, uncharged (at physiological pH), aliphatic amino acid that is used in the biosynthesis of proteins.
S3753	L-Leucine	Leucine ((S)-Leucine, Leu) is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing.
S3653	Spermidine trihydrochloride	Spermidine (4-Azaoctamethylenediamine) 是一种从腐胺和dcSAM中，通过亚精胺合成酶合成的天然聚胺。它是新型的自噬诱导剂，负向调控N-methyl-d-aspartate (NMDA)。
S3754	4-Hydroxybenzoic acid	4-Hydroxybenzoic acid (p-hydroxybenzoic acid, PHBA, para-Hydroxybenzoic acid, 4-hydroxybenzoate), also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. It is the most widely distributed aromatic organic acid in the vegetable kingdom.
S3893	Bornyl acetate	Bornyl acetate (Isobornyl, Bornyl acetic ether, 2-Camphanol), the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, exhibits anti-inflammatory property and it is used as an analgesic.
S3758	Sinomenine hydrochloride	Sinomenine (SN, Cucoline, Kukoline, Sabianine A), extracted from the Chinese medicinal plant, sinomenium acutum, is a potent anti-inflammatory and neuroprotective agent.
S3755	Betaine	Betaine (trimethylglycine, glycine betaine, lycine, oxyneurine), a methyl derivative of glycine first isolated from sugar beets, has been shown to have potential benefits for fighting heart disease, improving body composition, and helping promote muscle gain and fat loss because of its abilities to promote protein synthesis in the body.
S3757	2'-Deoxyinosine	2’-Deoxyinosine (Guanine deoxyriboside, Deoxyinosine) is the nucleoside form of hypoxanthine. It is a product of DNA damage that is formed from 2’-deoxyadenosine by adenosine deaminase or reactive nitrogen species. 2’-deoxyinosine enhances apoptosis induced by 5-fluorouracil in HT-29 and SW620 cancer cells.
S3770	Sodium Aescinate	Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.
S3681	Vitamin E Acetate	Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits. It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant.
S3853	Perillyl alcohol	Perillyl alcohol (Perilla alcohol, Isocarveol) is a monoterpene isolated from the essential oils of lavendin, peppermint, spearmint, cherries, celery seeds, and several other plants.
S3871	Muscone	Muscone (3-Methylcyclopentadecanone, Methylexaltone)是一种增香成分，一种有机化合物，是麝香气味的主要来源，也是一种有效的消炎剂。Muscone 可显著地下调LPDM诱导的炎症细胞因子水平，并抑制BMDM中 NF-κB 和 NLRP3 炎性小体的活化。Muscone 还可以显著地降低炎性细胞因子inflammatory cytokines (IL-1β, TNF-α, IL-6) 的水平。
S3762	Methylnonylketone	Methylnonylketone (2-Undecanone, IBI-246), also known as 2-Undecanone and IBI-246, is a natural non-toxic insect repellant compound.
S3789	Tiglic acid	Tiglic acid (Cevadic acid, Sabadillic acid, Tiglinic acid) is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. It is used in making perfumes and flavoring agents.
S3791	Succinic acid	Succinic acid (1,4-Butandioic Acid, 1,2-Ethanedicarboxylic acid, Amber acid, Asuccin, Butanedioic acid) is a crystalline organic acid which occurs in living tissue as an intermediate in glucose metabolism.
S3793	Phytic acid	Phytic acid (Inositol polyphosphate, Inositol hexakisphosphate) is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining.
S3794	Palmitic acid	Palmitic acid (Hexadecanoic acid, Cetylic acid) is the most common saturated fatty acid found in animals, plants and microorganisms with anti-tumor activity.
S3795	Phloretic acid	Phloretic acid (Desaminotyrosine, Hydro-p-coumaric acid, Phloretate, 3-(4-Hydroxyphenyl)propanoic acid) is a naturally occurring phenolic compound which can be produced by the hydrogenation of p-coumaric acid or synthesized from phloretin, a by-product of apple tree leaves.
S3796	Rebaudioside A	Rebaudioside A (Stevia Extract, Reb A, Glycoside A3, Stevioside A3), an natural sweetening ingredient extracted from the stevia leaf, is used in powder or liquid form to heighten sweetening intensity and improve taste.
S3797	Helicide	Helicide (4-formylphenyl-O-β-d-allopyranoside), a main active constituent from seeds of the Chinese herb Helicia nilagirica, has been reported to exert a sedative, analgesic and hypnotic effect, and is used clinically to treat neurasthenic syndrome, vascular headaches and trigeminal neuralgia.
S3799	Gentisic acid	Gentisic acid (2,5-dihydroxybenzoic acid, 5-Hydroxysalicylic acid, Hydroquinonecarboxylic acid, DHB), an active metabolite of salicylic acid degradation, has a broad spectrum of biological activity, such as anti-inflammatory, antirheumatic and antioxidant properties.
S3717	Testosterone Enanthate	Testosterone Enanthate (Testosterone heptanoate, NSC-17591)是一种雄激素和合成代谢类固醇，用于治疗雄性素补疗。
S3802	Trigonelline Hydrochloride	Trigonelline (Nicotinic acid N-methylbetaine, Coffearine, Gynesine), a major alkaloid component of fenugreek, has hypoglycemic, hypolipidemic, neuroprotective, antimigraine, sedative, memory-improving, antibacterial, antiviral, and anti-tumor activities, and also has been shown to reduce diabetic auditory neuropathy and platelet aggregation.
S3803	Angelic acid	Angelic acid ((Z)-2-Methylbut-2-enoic acid) is a monocarboxylic unsaturated organic acid that is mostly found in the plants of the family Apiaceae.
S3812	Monocrotaline	Monocrotaline (MCT, Crotaline) is an 11-membered macrocyclic pyrrolizidine alkaloid (PA) that causes a pulmonary vascular syndrome in rats characterized by proliferative pulmonary vasculitis, pulmonary hypertension, and cor pulmonale.
S3886	Quinic acid	Quinic acid (Chinic acid, Kinic acid) is a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid.
S3887	α-L-Rhamnose monohydrate	α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate, α-L-Rhamnopyranose monohydrate) is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
S3742	Cholic acid	Cholic acid是一种天然胆汁酸，在水中不可溶，用来治疗具有合成胆汁酸遗传缺陷的患者。
S3679	Flavanone	Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one)具有较强的抗氧化和清除自由基活性，可能可减少某些慢性疾病的风险、阻滞一些心血管疾病以及某些癌症。Flavanones还具有抗病毒、抗菌、消炎活性，对毛细管脆性有一定改善效果、抑制人血小板凝聚、抗溃疡、降低过敏反应。
S4808	L-Cystine	L-Cystine is the oxidized dimer form of the amino acid L-cysteine which is a non-essential amino acid of the human body. It is required for wound healing and formation of epithelial tissue.
S4811	VitaMin U	Vitamin U (Methylmethioninesulfonium Chloride, Cabagin-U, Smethylmethionine) is a vitamin found in green vegetables. It is used in the treatment of peptic ulcers, colitis, and gastritis and has an effect on secretory, acid-forming, and enzymatic functions of the intestinal tract.
S5107	Riboflavin phosphate sodium	Riboflavin phosphate sodium (Flavin mononucleotide, riboflavin-5'-phosphate, FMN, Vitamin B2 Phosphate Sodium Salt) is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue-light photo receptors.
S5108	Tylosin	Tylosin (Fradizine, Tylocine, Tylosine, Tylosin A) is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
S3626	Sesamol	Sesamol (1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol)是一种天然有机化合物，是油中主要的抗氧化成分，具有化学防癌、抗诱变剂和抗毒肝素活性。它能诱导癌细胞和心血管细胞凋亡。
S3625	Tyramine	Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) 是一种来源于氨基酸酪氨酸的天然微量胺，是一种儿茶酚胺释放试剂。
S3624	Quinolinic acid	Quinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN)是犬尿氨酸途径中的具有神经活性的代谢物，是N-methyl-D-aspartate (NMDA)受体的激动剂。
S3629	Syringic acid	Syringic acid (NSC 2129, SYRA) 是一种有效的抗氧化中草药，是一种新兴的营养食品。它具有潜在的抗血管生成、抗糖基化、抗高血糖、神经保护和增强记忆的活性。
S3630	Methyl Vanillate	Methyl Vanillate是枳椇子成分之一，在体外能激活Wnt/β-catenin信号通路并诱导成骨分化。
S5362	Citicoline	Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.
S5368	Lactitol	Lactitol is a versatile, reduced calorie sweetener derived from natural milk sugar, used in a wide variety of sweetening applications.
S4955	Acetosyringone	Acetosyringone (Acetosyringenin) is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions.
S5571	L-Asparagine	L-Asparagine (2-Aminosuccinamic acid, alpha-aminosuccinamic acid) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
S5594	α-Terpineol	α-Terpineol, a natural monoterpene, is the major component of essential oils of several species of aromatic plants such as Origanium vulgare L. and Ocimum canum Sims which are widely used for medicinal purposes. It is widely used in the manufacturing of cosmetics, soaps, perfumes, antiseptic agents and is considered one of the most frequently used fragrance compounds.
S5576	Benzyl acetate	Benzyl acetate (Acetic acid benzyl ester, Benzyl ethanoate, Phenylmethyl), usually found in alcoholic beverages, is a flavouring agent.
S5585	Citronellal	Citronellal (Rhodinal, 2,3-Dihydrocitral), a monoterpenoid found in oil of citronella, lemon, and lemon grass, has insect repellent properties and is used in perfumes.
S5598	p-Cymene	p-Cymene (4-Isopropyltoluene, 4-Methylcumene, Paracymene) is a naturally occurring aromatic organic compound produced by high purity separate technique which is applied in distilling of gum turpentine oil.
S3675	Umbelliferone	Umbelliferone (7-hydroxycoumarin, hydrangine, skimmetine, beta-umbelliferone) is a 7-hydroxycoumarin that is a pharmacologically active agent. It is a fluorescing compound used as a sunscreen agent and shows good inhibitions of DPPH, hydroxyl, superoxide anion and ABTS radicals with anti-inflammatory, anti-hyperglycaemic, molluscicidal and anti-tumor activities.
S3677	Cinnamic acid	Cinnamic acid (Benzenepropenoic acid, Isocinnamic acid, trans-Cinnamic acid, Phenylacrylic acid), a naturally occurring aromatic fatty acid of low toxicity, induces cytostasis and a reversal of malignant properties of human tumor cells in vitro.
S3661	2-Methoxy-1,4-naphthoquinone	2-Methoxy-1,4-naphthoquinone, isolated from the leaves of Impatiens glandulifera, specifically suppressed the expression of PKC βI, δ, and ζ in a concentration-dependent manner in Raji cells.
S3652	3-Nitropropionic acid	3-Nitropropionic acid (β-Nitropropionic Acid, 3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain.
S5513	Calcium D-saccharate tetrahydrate	Calcium D-saccharate tetrahydrate (Calcium Saccharate, D-Saccharic acid calcium salt, D-Glucaric acid calcium salt) is the calcium salt form of glucaric acid, a natural substance found in many fruits and vegetables, with potential anti-cancer property.
S5518	D-Glucose 6-phosphate disodium salt	D-Glucose 6-phosphate disodium salt is the disodium salt form of D-Glucose 6-phosphate, a common form of glucose within the cell, participating in two major metabolic pathways: glycolysis and the pentose phosphate pathway. It can be coverted to glycogen or starch for storage.
S2416	Chondroitin sulfate	Chondroitin sulfate是一种硫酸化糖胺多糖（GAG），组成交替糖分包括乙酰半乳糖胺和葡萄糖醛酸。
S5327	Meisoindigo	Meisoindigo (N-Methylisoindigotin, Methylisoindigotin, Dian III), a derivative of Indigo naturalis, is an active compound of a Chinese anti-leukemia medicine that has been effectively used in the treatment of chronic myelogenous leukemia (CML).
S5599	Sodium cholate	Sodium cholate (NaCh) is the sodium salt of the naturally occurring cholic acid, a bile salt produced by the liver, with strong solubilization capacity of water-insoluble substances.
S5575	2-Benzoxazolinone	2-Benzoxazolinone (BOA, 2-Hydroxybenzoxazole), a well-known allelochemical with strong phytotoxicity, is a potential herbicidal candidate and probably functions via interfering with auxins or disrupting membrane integrity.
S5579	Chelidonic acid	Chelidonic acid (Jerva acid, Jervaic acid, γ-Pyrone-2,6-dicarboxylic acid) 是在几种植物中发现的次级代谢产物，对实验动物的过敏性疾病具有治疗潜力。Chelidonic acid 通过阻断HMC-1细胞中的 NF-κB 和 caspase-1 来抑制 IL-6 的产生。Chelidonic acid 也是 glutamate decarboxylase 的抑制剂，其Ki值为1.2 μM。
S5588	Creatine	Creatine (Methylguanidoacetic acid) 是一种天然存在于脊椎动物中的含氮有机酸。Creatine 可以通过抑制 IFN-γ receptors 与 JAK2 的相互作用来抑制 JAK-STAT1 信号传递，以ATP非依赖性的方式促进三磷酸腺苷（ATP）的循环，从而抑制下游促炎基因表达。
S5614	(+)-Longifolene	(+)-Longifolene is a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins.
S3619	Citicoline sodium	Citicoline (CDP-choline) 是细胞膜主要的磷脂--卵磷脂合成的必要中间产物。它能够提高血浆促肾上腺皮质激素水平以及强化血清促甲状腺素水平。
S5595	3-Carene	3-Carene (Carene, Delta-3-Carene)是在从松树中提取的精油中的双环单萜。 3-Carene对 COX-2 过表达和LPS诱导的Raw264.7巨噬细胞迁移具有强大的药理作用。3-Carene被证明可显着刺激 alkaline phosphatase 的活性和表达，是成骨细胞分化的早期标志。
S5376	Decyl aldehyde	Decyl aldehyde (Decanal, Capraldehyde, Decanaldehyde) is a naturally occuring organic compound that is used in fragrances and flavoring.
S5551	6-Paradol	6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities.
S5379	Fenchyl Alcohol	Fenchyl Alcohol is used as a flavoring agent to provide a pine, herbal, lemon, or floral taste to food and drink.
S5530	Geraniol	Geraniol is a terpene alcohol occurring in the essential oils of several aromatic plants used in the flavour and fragrance industries. It also exhibits insecticidal and repellent properties and used as a natural pest control agent exhibiting low toxicity.
S5237	Dihydroartemisinic acid	Dihydroartemisinic acid is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal herb that is widely used to treat Malaria.
S5516	Ellagic Acid hydrate	Ellagic acid is a potent inhibitor of protein kinase CK2 with IC50s of 0.04, 2.9 and 3.5 μM for CK2, Lyn and PKA respectively. It shows potent antioxidant, anti-mutagenic and antidepressant properties.
S3612	Rosmarinic acid	Rosmarinic acid (RA, Rosemary acid) 是一种天然的羟化化合物。它具有阻止补体结合、抑制脂肪氧合酶和环氧煤活性的功能，通过抑制NF-κB激活信号中IKK-β的活性、抑制CCL11和CCR3的表达。
S3609	Berbamine dihydrochloride	Berbamine (BA, BBM) dihydrochloride 是一种从中草药黄芦木中分离而来的双苄基异喹啉类天然产物。它是bcr/abl的新型抑制剂，具有有效的抗白血病活性，是NF-κB的抑制剂。Berbamine (BA, BBM) dihydrochloride 通过靶向 Ca²⁺/calmodulin-dependent protein kinase II (CaMKII) 抑制癌细胞的生长，并诱导人骨髓瘤细胞凋亡。
S5459	Aucubin	Aucubin (Rhinanthin), an iridoid glycoside existing in medicinal plants, has been reported to show an anti-inflammatory activity by suppression of TNF-α production in murine macrophages.
S5471	Monotropein	Monotropein, an iridoids glycoside isolated from the roots of Morinda officinalis How, has been demonstrated to exhibit anti-inflammatory activity.
S5452	Sanguinarine chloride	Sanguinarine, a plant alkaloid, is a potent and specific protein phosphatase (PP) 2C inhibitor.
S5458	Verbascoside	Verbascoside (Acteoside, Kusaginin), a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.
S5467	Asarinin	Asarinin (Sesamin, Fagarol, Pseudocubebin, Episesamin, Eleutheroside B4), isolated as a racemate from the shrub Zanthoxylum alatum, is usually used as a dietary fat-reduction supplement.
S5455	Akebia saponin D	Akebia saponin D (Asperosaponin VI), the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
S5553	Kasugamycin hydrochloride	Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S5529	Galangin	Galangin (3,5,7-trihydroxyflavone; Norizalpinin), a naturally occuring flavonoid found in herbs, is a well-known antioxidant and also an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor.
S5453	Hyperoside	Hyperoside (Hyperin, Quercetin 3-galactoside), a naturally occuring flavonoid compound, exerts multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.Hyperoside can inhibit activation of the NF-κB signaling pathway.
S5460	Vitexin-2-O-rhaMnoside	Vitexin-2-O-rhamnoside (2''-O-Rhamnosylvitexin, Apigenin-8-C-glucoside) is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge. var major N. E. Br. It has many biological and pharmacological activities, such as antioxidation and treating heart disease.
S5468	Kaempferol-3-O-glucorhamnoside	Kaempferol 3-neohesperidoside (Kaempferol 3-neohesperidoside), isolated from the herbs of Delphinium grandiflorum L., has insulin-like properties in terms of glucose lowering.
S5465	Morroniside	Morroniside, an iridoid glycoside, is the main active ingredient from Cornus officinalis Sieb. et Zucc. and Sambucus williamsii Hance. It has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption.
S5463	Curcurbitacin IIA	Curcurbitacin IIA (Cucurbitacin Iia, CuIIa, Hemslecin A, Dihydrocucurbitacin Q1) is the major active component of the Helmseya amabilis root and is known to have antiviral and anti-inflammatory effects.
S5469	Bavachin	Bavachin (Corylifolin) is a phytoestrogen purified from natural herbal plants such as Psoralea corylifolia. It acts as a weak phytoestrogen by binding and activating the ER.
S5462	5-O-Methylvisammioside	5-O-Methylvisammioside is a naturally occuring product isolated from Saposhnikovia Divaricata and has analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation effects.
S5451	Ferulic acid methyl ester	Ferulic acid methyl ester (Methyl Ferulate, Methyl 4'-hydroxy-3'-methoxycinnamate) is a lipophilic derivative of ferulic acid, which is a hydroxycinnamic acid that is abundant in plants. It shows the strongest antioxidant activity and can protect against inflammation and cancer.
S5456	Isobavachalcone	Isobavachalcone (Corylifolinin), a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S5512	Juglone	Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone), a natural naphthoquinone found in the black walnut and other plants, has moderate antifungal activity and growth-stimulating effects to many types of plants. It sometimes can be used as an herbicide, as a dye for cloth and inks, and as a coloring agent for foods and cosmetics.
S3880	Schisantherin A	Schisantherin A (Gomisin C, Schisanwilsonin H, Arisanschinin K)是一种五味子红素，具有止咳、镇静、消炎、抗骨质疏松、神经保护、增强认知和心脏保护活性。Schisantherin A 也可通过IκBα降解抑制p65-NF-κB向核内移位。
S3882	Brassinolide	Brassinolide是来源于Brassica napus pollen的植物类脂醇，可促进细胞延长、细胞分裂，从而调节植物生长和发育。
S2376	Ammonium Glycyrrhizinate	Ammonium Glycyrrhizinate (AMGZ, Glycyram, Glycyrrhizin ammonium salt, Glycyrrhizic acid ammonium salt)是来自Licorice root的一种独特产品，具有极高的甜味。Ammonium Glycyrrhizinate 是 HMGB1 的直接抑制剂，具有抗炎、抗肿瘤、抗糖尿病的作用。Ammonium Glycyrrhizinate 可抑制几种不相关的DNA和RNA病毒的生长和细胞病理。Ammonium Glycyrrhizinate 还可抑制 hepatic delta 4-5-reductase 和 11 beta-hydroxysteroid dehydrogenase。
S2291	Diosgenin	Diosgenin 是一种类固醇皂甙元，为半合成孕激素的前体，在早期与口服避孕药一起使用。
S3776	Sophoricoside	Sophoricoside (SOPH)是一种分离自槐花（豆科）的异黄酮，具有多种药理作用，如消炎、抗癌、抑制免疫力等效应。
S5249	Coptisine chloride	Coptisine (Q-100696, NSC-119754)是一种分离自黄连的吲哚联啶生物碱，具有抗糖尿病、抗菌、抗病毒、抗肝癌和抗白血病效应。Coptisine chloride 也是一种有效的非竞争性 IDO 的抑制剂，对应的IC50值和Ki值分别为6.3 μM和5.8 μM。
S3879	Kaempferide	Kaempferide (4'-Methylkaempferol, 4'-O-Methylkaempferol, Kaempferol 4'-methyl ether) 是一种从山柰根中提取的天然产物，具有多种生物活性，包括抗癌、抗炎、抗氧化、抗菌抗病毒等活性。
S5049	Thiocolchicoside	Thiocolchicoside (Thiocolchicine 2-glucoside analog, Coltramyl) 是一种天然存在的配糖体，来源于嘉兰百合的花种中，具有抗炎和止痛活性，同时具有显著的惊厥作用。它也是GABAA receptor的拮抗剂。
S8279	Shikonin (C.I. 75535)	Shikonin (C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844)是一种 Pyruvate kinase M2 (PKM2) 有效的、特异的抑制剂。它是紫草的主要成分，紫草是一种中草药，具有多种生物活性。在细胞荧光淬灭试验中，Shikonin也是TMEM16A氯离子通道的抑制剂。Shikonin 通过抑制 tumor necrosis factor-α (TNF-α) 发挥抗炎作用，并可通过抑制 proteasome 来阻止 nuclear factor-κB (NF-κB) 信号途径的激活。
S3822	Schisandrin A	Schisandrin A (Sch A, Deoxyschizandrin, Wuweizisu A) is an active component of Schisandrae Fructus with liver-protective, antitumor, and antioxidant activities. It is an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM.
S4738	Arctiin	Arctiin (Arctigenin-4-Glucoside, NSC 315527) 是脂联素受体1的激动剂，具有抗肿瘤活性。
S3807	Dehydroandrographolide	Dehydroandrographolide, isolated from Andrographis paniculata (Burm. F.) Nees (Chuan-xin-lian), is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity.
S8132	Deguelin	Deguelin，一种从植物中分离出来的天然产物，是PI3K/Akt的抑制剂。
S3824	Quercitrin	Quercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.
S2383	Gastrodin	Gastrodin (Gastrodine) 是一种多元酚，是4-羟基苄醇的葡糖苷。
S2387	Lappaconite HBr	Lappaconite HBr是从Aconitum sinomontanum Nakai 提取的一种生物碱，具有抗炎作用。
S3910	4',7-Dimethoxyisoflavone	4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S3832	Euphorbiasteroid	Euphorbiasteroid (Euphorbia factor L1)是Euphorbia lathyris L.的成分之一，通过激活AMPK信号通路抑制3T3-L1细胞的脂肪形成，并通过促进Bcl-2/Bax信号通路诱导HL-60细胞凋亡。
S4884	Trans-Zeatin	Trans-Zeatina ((E)-Zeatin) 是植物生长激素的成员之一，属于细胞分裂素，可调节细胞分裂、发育和营养加工。Trans-Zeatina ((E)-Zeatin) 可抑制UVB诱导的 MMP-1 表达，c-Jun 活化和 ERK，JNK 磷酸化和 p38 MAP kinases (MAPKs) 呈剂量依赖性。
S2250	(-)-Epigallocatechin Gallate	(-)-Epigallocatechin Gallate(EGCG) 是从绿茶中分离的一种有效的抗氧化剂Polyphenol flavonoid。抑制telomerase和DNA methyltransferase，阻滞EGF受体和HER-2受体的激活，抑制脂肪酸合成酶以及谷氨酸脱氢酶的活性。
S2290	Dihydroartemisinin (DHA)	Dihydroartemisinin (DHA, Dihydroqinghaosu, β-Dihydroartemisinin, Artenimol)是一种Artemisinin 的半合成衍生物，从传统中药Artemisia annua分离而来的。Dihydroartemisinin 可通过抑制 NF-κB 激活来诱导自噬和凋亡。
S7409	Anisomycin	Anisomycin (Flagecidin, Wuningmeisu C) 是一种从Streptomyces griseolus提取的抗菌性抗生素，抑制蛋白质合成，也是一种 JNK 激活剂。Anisomycin 可促进自噬与凋亡。
S2295	Emodin	Emodin 是Rhubarb, Buckthorn 和 Japanese Knotweed (Fallopia japonica)中的一种泻药树脂，是6-甲基-1,3,8-三羟蒽醌.
S2320	Luteolin	Luteolin (Luteoline, Luteolol, Digitoflavone)是一种非选择性的PDE抑制剂，作用于PDE1-5，K_i分别为15.0 μM， 6.4 μM， 13.9 μM， 11.1 μM和9.5 μM。Phase 2.
S3818	Tectoridin	Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
S2302	Glycyrrhizin (NSC 167409)	Glycyrrhizin (NSC 167409, Glycyrrhizic Acid)是一种直接的高迁移率族蛋白1(HMGB1)的抑制剂，抑制依赖于HMGB1的炎症分子表达和氧化应激反应。调节p38和p-JNK信号通路，而不影响p-ERK信号通路。同时也能抑制11 beta-hydroxysteroid dehydrogenase。
S4603	Gallic acid	Gallic acid (3,4,5-Trihydroxybenzoic acid, Gallate, Benzoic acid)是一种在多种食物和草药中发现的有机酸，是有效的抗氧化剂。
S3841	Eleutheroside B	Eleutheroside B (syringin, Syringoside, Lilacin) is a phenylpropanoid glycoside first isolated from A. senticosus and has neuroprotective, tonic, adaptogenic, and immune-modulating properties.
S3845	Panaxadiol	Panaxadiol (20(R)-Panaxadiol) is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. It inhibits Ca2+ channels, decreasing channel open time and open state probability in vitro and displaying anti-arrhythmic potential.
S3847	Panaxatriol	Panaxatriol is a triterpene sapogenin originally found in species of Panax (ginseng) and exhibits anti-inflammatory, hepatoprotective, anti-arrhythmic, and antioxidative activities.
S3848	Hydroxytyrosol Acetate	Hydroxytyrosol acetate (HTy-Ac), an extra virgin olive oil (EVOO) polyphenol, exhibits antioxidant and anti-inflammatory effects.
S3778	Patchouli alcohol	Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S3912	Cephalotaxine	Cephalotaxine is a naturally occurring alkaloid which is the structural motif of a number of compounds and has shown promising anti-cancer properties.
S3930	Liquiritin	Liquiritin (LIQ, Liquiritoside, Liquiritigenin-4'-O-glucoside) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
S4758	Crocin	Crocin (Alpha-Crocin, Gardenia Yellow)是藏红花中的一种水溶性类胡萝卜色素，被用于调味品和着色食品中的香料。在传统中药中，被用作止痛剂或镇定剂。
S3874	Curcumenol	Curcumenol, a sesquiterpene isolated from Curcuma zedoaria, is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation.
S3877	Lysionotin	Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.
S3809	Imperatorin	Imperatorin (Ammidin, Marmelosin, Pentosalen, 8-Isoamylenoxypsoralen), a naturally occurring psoralen-type furanocoumarin, is a potent myorelaxant agent and acts as a calcium antagonist on vascular smooth muscle.
S3892	Isopsoralen	Isopsoralen (Angelicin), also known as angelicin, is a constituent of roots and leaves of angelica with anti-inflammatory activity and regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. It also shows antiviral activity against gammaherpesviruses.
S3908	4'-Demethylpodophyllotoxin	4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
S3938	Bisdemethoxycurcumin (BDMC)	Bisdemethoxycurcumin (BDMC)是一种天然纯在的姜黄素去甲氧基衍生物，具有多种生物活性，如消炎和抗癌活性。
S3890	Leonurine	Leonurine, an active alkaloid extracted from Traditional Chinese Medicine Herba leonuri, exerts several biological effects, such as antidiabetic, cardiovascular, and bovine mastitis protection.
S3816	Dehydroevodiamine	Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.
S5144	Neferine	Neferine ((R)-1,2-Dimethoxyaporphine) 是 Nelumbo nucifera 的天然成分，具有抗肿瘤功效。Neferine 可诱导肾癌细胞凋亡。Neferine 通过激活肌肉细胞中的 Akt/mTOR 通路和 Nrf2 来防止自噬。Neferine 可抑制 NF-κB 的激活。Neferine具有多种治疗作用，例如抗糖尿病，抗衰老，抗微生物，抗血栓形成，抗心律不齐，抗炎甚至抗HIV。
S4761	Thymoquinone	Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa with anti-inflammatory and anti-oxidant effects.
S3906	Astragalus polyphenols	Astragalus is a wonderful immune enhancing herb that has strong anti-viral activity and produces extra interferon in the body. It contains rich polyphenol with various effects including antioxidant and antiinflammatory actions.
S3907	Bulleyaconi cine A	Bulleyaconi cine A (Bulleyaconitine A, BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an "aconitine-like" alkaloid. It is a potent use-dependent blocker for both Nav1.7 and Nav1.8 Na+ currents.
S3909	Catalpol	Catalpol (Catalpinoside, Digitalis purpurea L), an iridoid glucoside contained richly in the roots of the small flowering plant species Rehmannia glutinosa Libosch, has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.
S3922	(-)-epigallocatechin	(-)-Epigallocatechin, widespread in plants, has been shown to exhibit anti-tumor, anti-cancer and anti-inflammatory functions.
S3923	Ginsenoside Rg1	Ginsenoside Rg1 (Ginsenoside A2, Panaxoside A, Panaxoside Rg1, Sanchinoside C1, Sanchinoside Rg1)是人参的主要活性成分之一，被确定为原人参三醇型，对多种癌症具有药理作用，例如神经保护和抗肿瘤作用。Ginsenoside Rg1 可降低 cerebral Aβ 水平并减少 NF-κB 核转移。
S3924	Ginsenoside Rb1	Ginsenoside Rb1 (Gypenoside Ⅲ) is a protopanaxadiol that has diverse in vitro and in vivo effects, including neuroprotective, anti-inflammatory, and anti-obesity actions. Ginsenoside Rb1, a main constituent of the root of Panax ginseng, inhibits Na+, K+-ATPase activity with IC50 of 6.3±1.0 μM. Ginsenoside also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. Ginsenoside Rb1 reduces the expressions of TLR3, TLR4 and TRAF-6, and down-regulates the levels of TNF-α, IFN-β and iNOS.
S3925	(-)-Epicatechin gallate	(-)-Epicatechin gallate (ECG) 是一种 cyclooxygenase-1 (COX-1) 的抑制剂，IC50值为7.5 μM。
S3926	Forsythin	Forsythin (FOR, Phillyrin) is an active ingredient extracted from the fruit of the medicinal plant Forsythia suspensa (Thunb.) Vahl and has been shown to have antioxidant, antibacterial and antiinflammatory properties.
S2317	L-(+)-Rhamnose Monohydrate	L-(+)-Rhamnose Monohydrate 是一种天然存在的脱氧糖。
S3901	Astragaloside IV	Astragaloside IV (AST-IV, AS-IV) is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. AS-IV suppresses activation of p-Akt, p-mTOR, p-NF-κB and p-Erk1/2.
S3915	Gracillin	Gracillin, a kind of steroidal saponin isolated from the root bark of wild yam Dioscorea nipponica, has been reported to exert antitumor activity.
S3916	Macranthoidin B	Macranthoidin B (Macranthoiside I) is a major bioactive saponin in rat plasma after oral administration of extraction of saponins from Flos Lonicerae.
S3920	7β-Hydroxylathyrol	7β-Hydroxylathyrol (7beta-Hydroxylathyrol, 7-Hydroxylathyrol) is natural occuring product extracted from the seeds of Euphorbia lathyris L.
S3921	Lathyrol	Lathyrol is a natural product that is used for cancer treatment.
S3931	Ginsenoside Rd	Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.
S3765	Picroside II	Picroside II (6-Vanilloylcatalpol, Vanilloyl catalpol) is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological activities.
S3875	Alpinetin	Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities.
S3878	Bavachinin	Bavachinin (7-O-Methylbavachin) ia a novel natural pan-PPAR agonist from the fruit of the traditional Chinese glucose-lowering herb malaytea scurfpea. It shows stronger activities with PPAR-γ than with PPAR-α and PPAR-β/δ (EC50 = 0.74 μmol/l, 4.00 μmol/l and 8.07 μmol/l in 293T cells, respectively).
S3881	Scopoletin	Scopoletin (Esculetin 6-methyl ether, Gelseminic acid, 6-Methylesculetin, Chrysatropic acid) is the main bioactive constituent of flower buds from Magnolia fargesii with anti-inflammatory, hypouricemic, and antioxidant activities.
S3883	Protopine	Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.
S3884	Jatrorrhizine	Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
S3800	Lycorine hydrochloride	Lycorine (Galanthidine, Amarylline, Narcissine, Licorine), a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. It is an HCV inhibitor with strong activity.
S3801	Sodium Houttuyfonate	Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
S3804	Alpha-Mangostin	Alpha-mangostin is the main xanthone purified from mangosteen and has health promoting benefits including anti-bacterial, anti-inflammatory, anti-oxidant, anti-cancer and cardioprotective activities. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. Alpha-mangostin is also an agonist of human STING.
S3808	Mangiferin	Mangiferin (Alpizarin, Chinomin, Hedysarid) is a bioactive compound that demonstrates many health perspectives and has been used to prepare medicinal and food supplements. Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50.
S3810	Scutellarin	Scutellarin (Breviscapine, Breviscapin, Scutellarein-7-glucuronide)是从中草药黄芩Scutellaria baicalensis和灯盏细辛Erigeron breviscapus中提取的主要活性类黄酮，具有许多药理作用，例如抗氧化、抗肿瘤、抗病毒和抗炎活性。Scutellarin 可以下调HCC细胞中的 STAT3/Girdin/Akt 信号传导，并抑制破骨细胞中RANKL介导的 MAPK 和 NF-κB 信号通路。
S3811	Ginsenoside Re	Ginsenoside Re (Ginsenoside B2, Panaxoside Re, Sanchinoside Re, Chikusetsusaponin Ivc)是三七的提取物、人参中的主要人参皂苷，属于20(S)-原人参三醇组 (protopanaxatriol group)。它具有多种体外和体内作用，包括血管舒张作用，抗氧化剂，抗高血脂和血管生成作用。Ginsenoside Re 会降低 β-amyloid protein (Aβ) 并通过抑制 JNK 和 NF-κB 起到抗炎的作用。
S3891	Vincamine	Vincamine (Angiopac, Devincan, Equipur, Minorin, Novicet, Oxybral, Perval, Sostenil, Tripervan), an indole alkaloid found in the leaves of V. minor and C. roseus, is a peripheral vasodilator that increases blood flow to the brain.
S3813	Bakuchiol	Bakuchiol ((S)-(+)-Bakuchiol) is a meroterpene phenol abundant in seeds and leaves of the plant Psoralea corylifolia. It has anti-inflammatory and antimicrobial activities.
S3919	Hederacoside C	Hederacoside C (HDC, Kalopanaxsaponin B) is one of the active ingredients in Hedera helix leaf extract (Ivy Ex.) and used to treat respiratory disorders.
S3837	Echinocystic acid	Echinocystic acid (EA), a natural triterpone enriched in various herbs, displays a range of pharmacological activities including anti-inflammatory and antioxidant effects.
S3844	Rosavin	Rosavin, a cinnamyl alcohol glycoside found in the plant Rhodiola rosea, possesses antidepressant and anxiolytic activities.
S3846	Eupatilin	Eupatilin (NSC 122413), a major flavonoid from Artemisia plants, possesses various beneficial biological effects including anti-inflammation, anti-tumor, anti-cancer, anti-allergy, and anti-oxidation activity.
S3779	cis-Anethole	Anethole ((Z)-Anethole, Cis-p-Propenylanisole, Cis-p-Anethole) has two isomers, the cis(Z) isomer being 15-38 times more toxic to animal than the trans(E) isomer. cis-Anethole is found in anise and Only a low level is permitted in flavours.
S3782	Neomangiferin	Neomangiferin (Mangiferin 7-glucoside), a natural xanthone C-glycoside mainly obtained from the well-known traditional Chinese medicine rhizoma of Anemarrhena asphodeloides, exhibits antidiabetic activity and antiosteoporotic action.
S3783	Echinacoside	Echinacoside, a natural polyphenolic compound, has various biological activities, such as antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative actions.
S3777	Gentiopicroside	Gentiopicroside (GE, Gentiopicrin), a naturally occurring iridoid glycoside, inhibits CYP2A6 and CYP2E1 with IC50 values of 21.8μg/ml and 594μg/ml, respectively in human liver microsomes, and dose not inhibit CYP2C9, CYP2D6, CYP1A2 or CYP3A4 activities.
S3784	Obacunone (AI3-37934)	Obacunone (AI3-37934, CCRIS 8657), a natural compound present in citrus fruits, has been demonstrated for various biological activities including anti-cancer and anti-inflammatory properties. It significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM; also a novel activator of Nrf2.
S3786	Glabridin	Glabridin (Q-100692, KB-289522, LS-176045), one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory.
S3787	Picroside I	Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S3780	Secoisolariciresinol diglucoside	Secoisolariciresinol diglucoside (SDG), a plant lignan isolated from flaxseed, has strong antioxidant activity, cardioprotective effects, reduces the blood levels of low-density lipoprotein cholesterol, and reduces the risk of hormone related cancer.
S3914	α-Hederin	α-hederin is a water-soluble pentacyclic triterpenoid saponin which has shown hemolytic and apoptotic properties.
S3929	Liquiritigenin	Liquiritigenin (4',7-Dihydroxyflavanone), the most active estrogenic compound from the root of Glycyrrhizae uralensis Fisch, selectively binds to ERβ with an IC50 value of 7.5 μM and activates multiple ER regulatory elements and native target genes with Erβ but not ERα.
S3932	Astilbin	Astilbin (Isoastilbin, Neoastilbin, Neoisoastilbin, Taxifolin 3-O-rhamnoside), a flavonoid compound isolated from the rhizome of Smilax glabra Roxb, displays anticancer, antioxidative, anti-inflammatory, and immunosuppressive activities.
S3760	Stachydrine hydrochloride	Stachydrine is isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits. It has potent anti-metastatic activity and cardioprotective effects. Stachydrine hydrochloride is the major active constituent of Herba Leonuri, which is a potential therapy for cardiovascular diseases. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities.
S3764	Isoferulic Acid	Isoferulic acid (Hesperetic acid, Hesperetate, Isoferulate), a major active ingredient of Cimicifuga heracleifolia, shows anti-inflammatory, antiviral, antioxidant, and antidiabetic properties.
S3766	Tanshinone IIA sulfonate sodium	Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA isolated as the main pharmacologically active natural compound from a traditional Chinese herbal medicine, the dried root of Salvia miltiorrhiza Bunge known as Danshen. Sodium tanshinone IIA sulfonate (STS) is a potent negative allosteric modulator of the human purinergic receptor P2X7. Sodium tanshinone IIA sulfonate (STS) inhibits the activity of CYP3A4 and store-operated Ca2+ entry (SOCE) through store-operated Ca2+ channels (SOCC) via downregulating the expression of transient receptor potential canonical proteins (TRPC).
S3771	Stachydrine	Stachydrine (Proline betaine, L-stachydrine, Methyl hygrate betaine) is a quaternary ammonium derivative of proline that occurs widely in Medicago species. It is an osmoprotective compound found in urine. Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.
S3773	Tyrosol	Tyrosol (4-Hydroxyphenylethanol, 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethanol) is an antioxidant that is naturally present in several foods such as wines and green tea and is present most abundantly in olives. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
S3775	Ligustrazine hydrochloride	Ligustrazine hydrochloride (Tetramethylpyrazine, Tetrapyrazine) is a chemical compound found in natto and in fermented cocoa beans with anti-inflammation, antioxidant, antiplatelet, and antiapoptosis activities.
S5101	Tabersonine hydrochloride	Tabersonine, an ingredient extracted from the bean of Voacanga africana, is a potent inhibitor against Aβ(1−42) aggregation and toxicity.
S2318	Lappaconitine	Lappaconitine (LC) is a natural diterpenoid alkaloid (DTA), acting as a human heart sodium channel blocker and possessing a wide range of biological activities, including anti-arrhythmic, anti-inflammatory, antioxidative, anticancer, epileptiform etc.
S3815	Mogroside V	Mogroside V is a natural cucurbitane glycoside which has a sweetening strength of 250 times that of sucrose and is derived from mature fruit of luo-han-guo (Siraitia grosvenorii, monk fruit).
S3819	Decursinol angelate	Decursinol angelate is a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.
S3820	Dehydroevodiamine hydrochloride	Dehydroevodiamine (DHE), a major phytochemical in fruits of Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.
S3825	Glycitin	Glycitin (Glycitein-7-β-O-glucoside), a natural isoflavone isolated from legumes, has antibacterial, antiviral and estrogenic activities and may exerts preventative effects on alcoholism, cardiovascular and cerebrovascular diseases and some types of cancer.
S3826	Hydroxytyrosol	Hydroxytyrosol (3,4-dihydroxyphenylethanol) is one of the main phenolic components of olive oil with excellent antioxidant, antimicrobial and anticarcinogenic activities.
S3827	Royal jelly acid	Royal jelly acid (10-Hydroxy-trans-2-decenoic acid, 10H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysaccharide (LPS)- and interferon (IFN)-γ-stimulated macrophage responses, inhibition of T-cell proliferation and anti-rheumatoid activity.
S3828	Orcinol glucoside	Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.
S3829	Isoalantolactone	Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S3834	Astaxanthin	Astaxanthin (β-Carotene-4,4'-dione, Trans-Astaxanthin), a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability.
S3835	Loganin	Loganin (Loganoside) is an iridoid glycoside first isolated from the seeds of Strychnos nux-vomica, a member of the Loganiaceae family. It is a non-competitive inhibitor of BACE1 with IC50 of 47.97 μM an also inhibits AChE and BChE with IC50 values of 3.95 μM and 33.02 μM, respectively.
S3836	6-Gingerol	6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.
S3838	Carnosic acid	Carnosic acid (Salvin) is a phenolic diterpene, endowed with antioxidative and antimicrobial properties. It is increasingly used within food, nutritional health and cosmetics industries.
S3840	Baohuoside I	Baohuoside I (Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.
S3842	Isoquercitrin	Isoquercitrin (Hirsutrin, 3-Glucosylquercetin, Quercetin 3-o-glucopyranoside), a flavonoid compound with anticancer activity isolated from Bidens bipinnata L, is an inhibitor of Wnt/β-catenin that acts downstream of the β-catenin nuclear translocation.
S3833	Amentoflavone	Amentoflavone (Didemethyl Ginkgetin) is a biflavonoid originally isolated from Selaginella with antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities.
S3943	Lycopene	Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. It is a natural antioxidant.
S3960	Higenamine hydrochloride	Higenamine (Norcoclaurine, (+-)-Demethylcoclaurine), also known as Norcoclaurine HCl, is a non-selective β2 adrenoceptor agonist which is a chemical compound naturally occurring in a number of plants.
S3941	Pinocembrin	Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone)是制药工业中多功能黄酮类分子，它具有很多药学活性，如抗菌、消炎、抗氧化和抗癌活性。
S5104	Tea polyphenol	Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.
S3939	4'-Methoxyresveratrol	4-Methoxyresveratrol is a stibenoid found in the Chinese herb Gnetum cleistostachyum. 4'-Methoxyresveratrol alleviates AGE-induced inflammation through suppressing RAGE-mediated MAPK/NF-κB signaling pathway and NLRP3 inflammasome activation.
S3940	3'-Hydroxypterostilbene	3'-Hydroxypterostilbene (3'-HPT)是苦马豆和紫檀木心中的活性成分之一，可能对治疗不同类型的恶性血液肿瘤有效。3'-Hydroxypterostilbene 可通过诱导凋亡和自噬，从而有效地抑制人结肠癌细胞的生长，对COLO 205，HCT-116和HT-29 cells的IC50值分别为9.0 µM、40.2 µM和70.9 µM。3'-Hydroxypterostilbene 会抑制 PI3K/Akt/mTOR 信号通路中的p70S6K 和 p38MAPK信号通路，而激活ERK1/2, JNK1/2 信号通路。
S3614	Lupeol	Lupeol (Clerodol, Monogynol B, Fagarasterol, Farganasterol) 是一种显著的白桦脂酸型三萜烯，存在于植物、真菌和动物中，具有抗癌、抗原生动物、化学预防、消炎作用。
S3747	Levothyroxine sodium	Levothyroxine (L-T4, L-Thyroxine) 是源于甲状腺的主要激素，是甲状腺激素受体α和β的激动剂。
S3668	Thymopentin	Thymopentin (TP5) has immuno-regulatory activities. The immuno-regulatory actions of thymopentin on peripheral T cells are mediated by intracellular cyclic GMP elevations in contrast to the intracellular cyclic AMP elevations induced in precursor T cells that trigger their further differentiation to T cells.
S3608	Demethylzeylasteral (T-96)	Demethylzeylasteral (T-96)是从Tripterygium wilfordii Hook F.中分离出的活性成分，能够抑制UDP-glucuronosyltransferase (UGT)的亚型UGT1A6和UGT2B7，具有免疫抑制活性。
S3610	Cordycepin	Cordycepin (3'-Deoxyadenosine) is an adenosine analogue, which is readily phosphorylated to its mono-, di-, and triphosphate intracellularly. It has a very potent anti-cancer, anti-oxidant and anti-inflammatory activities.
S3613	Scoparone	Scoparone (6,7-dimethoxycoumarin, Aesculetin dimethyl ether, 6,7-Dimethylesculetin, Escoparone)是一种天然的有机化合物，是从中草药猪毛蒿中提取而来，具有抗凝、降血脂、抗氧化和抗炎作用。
S3615	Dehydrocostus Lactone	Dehydrocostus lactone (DHE)是一种天然的倍半萜内酯，抑制IKKβ活性、IκBα的磷酸化和降解、共激活子p300的招募、p50/p65 NF-κB的核转位及它们结合于COX2启动子上的能力。DHE具有抗炎、抗溃疡、抗肿瘤作用和免疫调节活性。
S3616	Asiaticoside	Asiaticoside (Ba 2742, BRN0078195, CCRIS8995, NSC166062, Emdecassol,Madecassol) 是Centella asiatica（积雪草）中的主要活性成分，通过抑制紫外线A诱导的ROS生成、阻止紫外线A依赖性的光老化。它还能通过MITF减少DNA结合。
S3606	Fangchinoline	Fangchinoline是双苄基异喹啉类生物碱，是HIV-1的新型抑制剂，具有缓解疼痛、降低血压和抗菌活性。
S4757	Dihydrotestosterone (DHT)	Dihydrotestosterone (DHT, androstanolone, stanolone, 5α-DHT)是一种内源性的雄激素性类固醇和激素，是雄激素受体的激动剂，其亲和力比睾酮高2-3倍，诱导雄激素受体信号的效力比睾酮高3倍。
S4752	Corticosterone (NSC-9705)	Corticosterone (NSC-9705, 17-deoxycortisol, 11β,21-dihydroxyprogesterone)是主要的压力激素，一种肾上腺皮质类固醇，具有作为盐皮质激素和糖皮质激素的活性。
S8291	Atractylenolide I	Atractylenolide I 是A. macrocephala根茎的主要类倍半萜烯类化合物。具有广谱的药理活性，如抗炎、促消化、抗氧化作用。
S4742	Rebaudioside C	Rebaudioside C (Dulcoside B) 属于甜菊糖苷（Steviol Glycosides）家族。它是甜叶菊Stevia rebaudiana Bertoni中的天然组分，是糖尿病患者和控制碳水化合物的治疗饮食中的天然甜味剂。
S4743	Wogonin	Wogonin (Vogonin)，在植物中发现的天然活性黄酮类化合物，是CDK9的抑制剂。在抑制CDK9的浓度下，对CDK2、CDK4和CDK6没有抑制作用。也可抑制N-acetyltransferase。
S4741	Danshensu	Danshensu (Salvianic acid A)，是一种传统中药中的中草药，具有潜在的抗肿瘤和抗血管生成的效果。Danshensu 可抑制 CYP2E1 和 CYP2C9，对应的IC50值分别为36.63 μm和 75.76 μm。
S4739	Oxyresveratrol	Oxyresveratrol (Tetrahydroxystilbene, 2,3',4,5'-tetrahydroxystilbene)是从Morus alba L.发现的天然化合物，对酪氨酸酶的多巴氧化酶活性具有有效抑制作用，能催化黑色素生物合成的限速步骤。
S4746	(20S)-Protopanaxadiol	20(S)-Protopanaxadiol (PPD, 20-Epiprotopanaxadiol)，人参皂苷在肠道的主要代谢物，是人参中的活性成分之一。20(S)-Protopanaxadiol 可在耐多种药物的癌细胞中抑制 P-glycoprotein。
S4735	Salvianolic acid B	Salvianolic acid B (Sal B, Lithospermate B, Lithospermic acid B)是一种抗氧化剂和自由基清除化合物，是从丹参中提取出来的最丰富的生物活性化合物。
S8318	Alantolactone	Alantolactone (helenin, helenine, Eupatal)，一种天然的桉烷类倍半萜内酯，能诱导activin/SMAD3信号、干扰Cripto-1/activin受体ⅡA型受体的相互作用。
S4707	Oleic Acid	油酸 Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid)是一种天然存在于多种动物和植物脂肪和油类中的脂肪酸。它常被用作制作油酸和乳液，并作为一种药物溶剂。
S4722	(+)-Catechin	(+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) 是抗氧化类黄酮，主要以(+)-catechin和(-)-epicatechin的形式存在于木本植物中。
S4723	(-)Epicatechin	(−)Epicatechin (L-Epicatechin, (-)-Epicatechol)是一种类黄酮，在可可、绿茶、红酒中常见。具有强的抗氧化、胰岛素类似作用，能改善心脏健康。
S4726	Lauric Acid	Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid)是饱和中链脂肪酸，在多种植物、动物油脂中都天然存在，是椰子油和棕榈仁油的主要成分。
S4719	Kynurenic acid	Kynurenic acid (Quinurenic acid, Kynurenate)是色氨酸通过犬尿氨酸途径代谢的天然代谢物，是一种广谱的兴奋性氨基酸拮抗剂。它是NMDAR, kainate receptor和AMPA receptor的拮抗剂。
S4711	Esculetin	Esculetin (Cichorigenin, Aesculetin)是在很多种天然植物产物中发现的香豆素衍生物，具有抗水肿、抗炎、抗肿瘤的生物和药理学特性，能抑制脂肪氧合酶。
S4728	3,3'-Diindolylmethane	3,3'-Diindolylmethane(DIM) 是indole-3-carbinol的主要消化产物，而indole-3-carbinol是十字花科蔬菜中一种潜在的抗癌物质。3,3'-Diindolylmethane(DIM) 是一种纯粹的 androgen receptor (AR) 的强拮抗剂。
S4708	Palmitoylethanolamide	Palmitoylethanolamide (PEA, Palmidrol, N-palmitoylethanolamine) 是一种内源性的脂肪酸酰胺，能在体外选择性激活PPAR-α，EC50为3.1±0.4 μM。
S4690	Escin	Escin (Aescin) 是在欧洲七叶树中所发现的皂苷混合物，具有抗炎、血管收缩的、血管保护作用。
S4686	Vitamin E	Vitamin E (D-alpha-Tocopherol) 是一种脂溶性的维生素，具有有效的抗氧化特性。它是有效的过氧化氢自由基清除剂并在很多组织中，非竞争性地抑制环氧酶活性。同时通过抑制VEGF基因转录，抑制血管生成和肿瘤休眠。
S4706	Eugenol	Eugenol (4-Allyl-2-methoxyphenol, 4-Allylguaiacol, Eugenic acid, Allylguaiacol)是一种自然存在的香味化合物，发现于丁香油和其他植物中。Eugenol通过增加组胺释放和细胞免疫发挥其生理作用。
S4539	Salicylic acid	Salicylic acid (2-Hydroxybenzoic acid)是一种水杨酸，植物中的天然化合物，是乙烯生物合成和环氧酶活性的抑制剂。
S4507	17-Hydroxyprogesterone	17-Hydroxyprogesterone (17-OHP)是一种内源性孕激素，是其他类固醇激素生物合成过程中的化学中间体。
S7867	Oleuropein	Oleuropein 是一种从橄榄叶中分离出的抗氧化多酚。Oleuropein 具有抗氧化、抗炎和抗动脉粥样硬化的作用，并在体外抑制脂肪细胞的分化。Oleuropein 抑制 PPARγ 活性。Oleuropein 通过直接抑制PPARγ转录活性发挥抗脂肪形成作用。Oleuropein 还可抑制aromatase。Oleuropein 可诱导凋亡。Phase 2。
S7594	Abscisic Acid (Dormin)	Abscisic Acid (Dormin, Abscisin II)是一种植物激素，参与许多植物发育过程，调节离子平衡和新陈代谢，并且抑制植物发芽和幼苗生长。
S7582	Anacardic Acid	Anacardic Acid (6-pentadecylsalicylic Acid)是一个有效的p300及p300/CBP相关因子 histone acetyltranferases的抑制剂，也具有抗细菌和抗微生物活性，抑制前列腺素合成，并抑制酪氨酸酶和脂肪氧合酶。
S8036	Butein	Butein，一种从漆树中分离的植物多酚，可以抑制酪氨酸激酶，NF-κB，STAT3和EGFR活化。
S7025	Embelin	Embelin (Embelic Acid, NSC 91874)，从矮地茶中分离的一种醌类化合物，是一种细胞凋亡的X染色体抑止剂(XIAP)的抑制剂，无细胞试验中IC50为4.1 μM。
S4916	Cyanidin Chloride	Cyanidin chloride 是一种花青素酚类抗氧化化合物，具有保护细胞的效果。
S4033	Sennoside A	Sennoside A (NSC 112929)，一种从大黄根茎中分离得到的刺激性泻药，在肠道中引起通便作用。
S4018	Sennoside B	Sennoside B，一种从大黄根茎中分离得到的刺激性泻药，抑制PDGF刺激的细胞增殖。
S2252	(+)-Usniacin	(+)-Usniacin (D-Usnic Acid)是在一些地衣中发现的天然存在的二苯并呋喃类衍生物。
S2253	3-Indolebutyric acid (IBA)	3-Indolebutyric acid(IBA)是一种植物激素，用于使许多商业植物生根园艺产品。
S2424	Hypoxanthine	Hypoxanthine是天然存在的嘌呤类衍生物，是尿酸合成的中间产物，由腺嘌呤核苷酸代谢而来，为黄嘌呤前体。
S2374	5-hydroxytryptophan (5-HTP)	5-Hydroxytryptophan (5-HTP, NSC-92523)，在Vitamin B6存在时，通过酶芳香族-L-氨基酸脱羧酶脱羧成羟色胺（5-hydroxytryptamine 或5-HT）。
S2256	4-Methylumbelliferone (4-MU)	4-Methylumbelliferone (4-MU)是透明质酸(HA)合成抑制剂，IC50为0.4 mM。
S2375	Aloin	Aloin (Barbaloin, Barbalin) 是有效的酪氨酸酶抑制剂，作用于HeLaS3细胞，IC50为97 μM。
S2258	Esculin	Esculin (Aesculin) 是一种在Horse chestnuts中发现的葡萄糖苷。
S2377	Biochanin A	Biochanin A (4-Methylgenistein) 是O-甲基异黄酮，是黄酮类的一种天然有机化合物。
S2259	Aloe-emodin	Aloe-emodin (NSC 38628, Rhabarberone) 是一种干扰素诱导剂，作用于JEV，IC50为1 μg/mL，作用于EV71，IC50为0.33 μg/mL。
S3071	Vanillin	Vanillin (FEMA 3107),香草醛,是一种食品添加剂。
S2260	Amygdalin	Amygdalin 最初从Prunus dulcis树的种子中分离的一种糖苷，也被称为苦杏仁。
S2379	Dioscin	Dioscin (Collettiside III, Saponin) 是皂苷提取的，Polygonatum Zanlanscianense Pamp分离的，抑制MDA-MB-435, H14, HL60, 和 HeLa 细胞系，IC50分别为 2.6, 0.8, 7.5, 和 4.5 μM。
S2261	Andrographolide	Andrographolide是一种Labdane类二萜，是药用植物Andrographis paniculata的主要生物活性成分
S2380	Diosmetin	Diosmetin (Luteolin 4-methyl ether)是在Spearmint, Oregano, 和许多其他植物中发现的生物类黄酮。
S2262	Apigenin (LY 080400)	Apigenin (NSC 83244, LY 080400)是一种有效的CYP2C9抑制剂，K_i为2 μM.。
S2263	Arbutin	Arbutin (Uva, p-Arbutin, β-Arbutin) 是一种酪氨酸酶 tyrosinase 抑制剂，对Monophenolase和Diphenolase的IC50值分别为0.9 mM 和 0.7 mM。
S2382	Evodiamine	Evodiamine (Isoevodiamine)是Evodiae Fructus中提取的一种生物碱。它能通过抑制IkB kinase活性抑制NF-kB的激活。
S2384	Hematoxylin	Hematoxylin (Hydroxybrazilin)易与某些金属离子，尤其是Fe（III）和Al（Ⅲ）盐，形成有色络合物。
S2266	Asiatic Acid	Asiatic acid (Dammarolic acid, Asiantic acid)是积雪草苷的糖苷配基，从植物积雪草中分离而来的，常用于伤口愈合。
S2386	Indirubin (NSC 105327)	Indirubin (NSC 105327) 是一种有效的细胞周期依赖性激酶和GSK-3β抑制剂，IC50约为 5 μM和0.6 μM。
S2267	Azomycin	Azomycin (2-Nitroimidazole) 是Nocardia mesenterica产生的抗生素。
S2268	Baicalein	Baicalein是CYP2C9和脯氨酰肽链内切酶抑制剂。
S2269	Baicalin (NSC-661431)	Baicalin (NSC-661431)是一种脯氨酰肽链内切酶抑制剂，影响GABA受体。
S2389	Naringin Dihydrochalcone	Naringin Dihydrochalcone 是一种新型甜味剂，是来自柚皮苷的一种人工甜味剂。也是一种CYP enzymes的抑制剂。
S2270	Bergenin	Bergenin (Cuscutin)是三羟基酸苷和4-O-甲基没食子酸的C-苷。
S2390	Polydatin	Polydatin (Piceid) 是从多年生草本Polygonum Cuspidatum Sieb.et Zucc的根茎提取的一种结晶组分。
S2271	Berberine chloride (NSC 646666)	Berberine chloride (NSC 646666, Natural Yellow 18)是异喹啉类生物碱的季铵盐。Berberine chloride 可激活 caspase 3 和 caspase 8，分裂 poly ADP-ribose polymerase (PARP) 和释放 cytochrome c。Berberine chloride 可降低 c-IAP1，Bcl-2 和 Bcl-XL 的表达。Berberine chloride 可通过 JNK 和 p38 MAPK 的持续磷酸化以及产生 ROS 来诱导凋亡。Berberine chloride 是一个 topoisomerase I 和 II 的双效抑制剂。Berberine chloride 也是一个潜在的自噬调节剂。
S2391	Quercetin (NSC 9221)	Quercetin (NSC 9221, Sophoretin, C.I. 75720)是蔬菜水果和白酒中的天然黄酮类化合物，是一种体外重组Sirt1蛋白的激活剂同时也是PI3K抑制剂，IC50为2.4 – 5.4 μM。Quercetin 可诱导凋亡和保护性的自噬。Phase 4。
S3600	Schisandrin B (Sch B)	Schisandrin B (Sch B)是中草药五味子(Turcz.)中含量最丰富的二苯并环辛二烯木酚素。它是一种安全的ATR和P-gp抑制剂。
S2273	β-Sitosterol	β-Sitosterol (SKF 14463, 22,23-Dihydrostigmasterol)是一种植物甾醇，与胆固醇具有相似的化学结构。
S2392	Sesamin	Sesamin (Fagarol, Fsesamin) 是从Fagara植物的树皮和芝麻油中分离的一种木脂素。
S2448	Gambogic Acid	Gambogic Acid (Guttatic Acid, Guttic Acid, Beta-Guttiferrin)激活caspases，EC50为0.78 - 1.64 μM，且完全抑制Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 和 Mcl-1，IC50分别为1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM 和 0.79 μM。
S2276	Bilobalide	Bilobalide 是一种存在于Ginkgo biloba中的有生物活性的萜内酯。
S2277	Caffeic Acid	Caffeic Acid是一种羟基肉桂酸，是一种天然存在的有机化合物。
S2281	Chrysin	Chrysin (NSC 407436) 是一种天然存在的Flavone，是由Passiflora caerulea花化学提取而来的。
S2282	Cinchonidine	Cinchonidine是一种生物碱，在有机化学中用于不对称合成。
S2422	Ipriflavone (Osteofix)	Ipriflavone (Osteofix)是小分子物质，用于抑制骨吸收。
S2285	Cryptotanshinone	Cryptotanshinone 是一种STAT3抑制剂，无细胞试验中IC50为4.6 μM，强烈抑制STAT3 Tyr705磷酸化，对STAT3 Ser727作用效果弱，对STAT1和STAT5没有作用效果。Cryptotanshinone 可诱导ROS依赖的自噬和线粒体介导的凋亡。
S2423	(S)-10-Hydroxycamptothecin	(S)-10-Hydroxycamptothecin (10-HCPT)是DNA拓扑异构酶I抑制剂，具有有效的抗肿瘤活性。
S2437	Rotundine	Rotundine是一种选择性多巴胺D1受体拮抗剂， IC50为166 nM。
S2287	Cytisine	Cytisine (Baphitoxine, Sophorine)是一种烟碱型乙酰胆碱受体激动剂。
S2289	Daidzin	Daidzin (Daidzoside, Daidzein 7-O-glucoside, Daidzein 7-glucoside)，一种植物天然有机化合物，也是一种异黄酮，是有效的、选择性的人类线粒体醛脱氢酶抑制剂，选择性抑制ALDH-I（Ki=20 nM）；而对ALDH-Ⅱ的效力至少低500倍（Ki=10 μM）。
S2385	Hordenine	Hordenine是一种苯乙胺生物碱具有抗菌特性。
S2394	Naringenin	Naringenin (NSC 34875, S-Dihydrogenistein, NSC 11855, Salipurol)是来自于食用植物的一种天然的主要黄酮类化合物，有益人体健康，具有生物活性，是一种抗氧化剂，自由基清除剂，抗炎，碳水化合物代谢启动子及免疫系统的调制剂。
S2292	Diosmin	Diosmin 是一种 aryl hydrocarbon receptor (AhR) 的激动剂。Diosmin 是一种半合成Phlebotropic药物，也是一种在各种柑橘类水果中发现的类黄酮。
S1973	Cyclocytidine HCl	Cyclocytidine (NSC 145668) 是Cytarabine的前体药物，是一种嘧啶核苷类似物，抑制DNA synthesis，主要用于治疗白血病。
S2296	Enoxolone	Enoxolone (Glycyrrhetin) 是一种通过甘草酸水解得到的β-香树脂醇型五环三萜衍生物。
S2395	Rheochrysidin	Rheochrysidin (Physcione)是大承气汤的主要成分之一，用于治疗炎症。
S2297	Ergosterol	Ergosterol是甾醇，是vitamin D2的生物前体（一种维生素原）。
S2396	Salidroside	Salidroside (Rhodioloside) 是一种糖苷类化合物，作用于SACC-2细胞增殖，IC50为4.99±0.23 μg/mL。
S2298	Fisetin	Fisetin 是有效的Sirtuin活化化合物(STAC)，可以调节Sirtuin。
S2397	Palmatine chloride	Palmatine chloride 是Palmatine的盐酸盐，是一种小檗碱类生物碱。
S2299	Formononetin	Formononetin (Formononetol, Biochanin B)是Astragalus根部的一种植物雌激素，是O-甲基异黄酮。
S2398	Coenzyme Q10 (CoQ10)	Coenzyme Q10 (CoQ10) 组成电子传递链，并参与细胞有氧呼吸。
S2300	Ferulic Acid	Ferulic Acid (Fumalic) 是一种羟基肉桂酸，是在Ferula assafoetida L或Ligusticum chuanxiong中发现的一种有机化合物。Ferulic acid 是一种新型的 fibroblast growth factor receptor (FGFR) 抑制剂，对FGFR1和FGFR2的IC50分别为3.78 μM和12.5 μM。
S2399	Dihydromyricetin	Dihydromyricetin (Ampelopsin, Ampeloptin)是具有良好性能的天然抗氧化剂。
S2301	Genistin (Genistoside)	Genistin (Genistoside, Genistine, Genistein 7-glucoside, Genistein glucoside)是在很多可以食用植物（如大豆和野葛）中发现的一种异黄酮。Genistin 通过调节 Estrogen Receptor α (ERα) 信号传导途径来减弱细胞生长并促进凋亡细胞死亡。
S2400	Rheic Acid	Rhein (Monorhein, NSC 38629, Rheinic) 是Rhubarb的组成部分，是从Rheum coreanum Nakai新鲜根茎分离得到的，具有抗炎和抗肿瘤活性。Rhein 是一种FTO (mRNA N⁶-methyladenine demethylase)的抑制剂，并且还可抑制 AlkB repair enzymes。
S2401	Sodium Danshensu	Sodium Danshensu是丹参素的单钠盐，是从Salvia miltiorrhiza Bge中分离的天然酚酸，是咖啡酸衍生物。
S2303	Gossypol Acetate	Gossypol Acetate (Gossypol Acetic acid, Pogosin, AT101) 是多酚醛，可渗透细胞，是一些脱氢酶（如乳酸脱氢酶、NAD-linked enzymes）的抑制剂。
S2402	Cyclovirobuxine D	Cyclovirobuxine D (Cyclovirobuxin D, Cyclovirobuxine, Bebuxine, CVB-D) 是从Buxus microphylla中提取的活性化合物，用于治疗急性心肌缺血。
S2304	Gramine	Gramine (Donaxine) 是一种从巨型芦苇中分离出的天然吲哚生物碱，是一种活性脂联素受体（AdipoR）激动剂，对AdipoR2和AdipoR1的IC50分别为3.2 µM和4.2 µM。禾胺也是人和小鼠 β2-Adrenergic receptor (β2-AR) 激动剂。
S2403	Tetrandrine (NSC-77037)	Tetrandrine (NSC-77037, Fanchinine, d-Tetrandrine)是来源于千金藤根部的一种双苯基异喹啉，一种钙离子通道抑制剂。
S2306	Gynostemma Extract	Gynostemma Extract (Gynostemma Pentaphyllum, Gypenoside)是一种从Gynostemma pentaphyllum提取而得的皂甙。
S2308	Hesperetin	Hesperetin是一种生物类黄酮，更具体而言，是一种二氢黄酮。
S2309	Hesperidin	Hesperidin (Cirantin)是在柑橘类水果中广泛存在的黄酮苷。
S2404	Isoliquiritigenin	Isoliquiritigenin 是Glycyrrhiza glabra根系分泌的一种类黄酮，能抑制醛糖还原酶，IC50为320 nM。具有抗肿瘤活性。
S2405	Sophocarpine	Sophocarpine 是人类ether-à-go-go相关基因(HERG)抑制剂，IC(50)为0.2 mM。
S2311	Hyodeoxycholic acid (HDCA)	Hyodeoxycholic (HDCA, NSC 60672) acid 是一种次要的胆汁酸，是肠道细菌的代谢产物之一。
S2406	Chrysophanic Acid	Chrysophanic Acid (Chrysophanol) 是Dianella longifolia中的一种天然蒽醌，是一种EGFR/mTOR通道抑制剂。
S2312	Icariin	Icariin是一种cGMP特异性的PDE5抑制剂，IC50为0.432 μM，作用于PDE5比作用于PDE4选择性高167倍。
S2407	Curcumol	Curcumol是常见的传统中药，具有抗肿瘤活性。
S2313	Indole-3-carbinol	Indole-3-carbinol是通过降解硫代葡萄糖酸盐芸苔葡萄糖硫苷而来的,广泛存在于十字花科蔬菜中。它能够抑制NF-κB和IκBα激酶的激活。
S2314	Kaempferol (NSC 407289)	Kaempferol (NSC 407289, Robigenin)是一种黄酮，是ERRα和ERRγ的反向激动剂。抑制topoisomerase I催化的DNA再连接和fatty acid synthase的活性。
S1450	Nanchangmycin	Nanchangmycin是一种聚醚抗生素，与Dianemycin结构相似，非常有效地防治广谱的有害线虫和昆虫，而对哺乳动物和植物没有作用效果。
S2316	Kinetin	Kinetin (6-Furfuryladenine) 是一种细胞分裂素，是一类植物激素，促进细胞分裂。通常用于植物组织培养，诱导愈伤组织形成（与生长素联用），且诱导再生芽的发生。
S2319	Limonin	Limonin又称Limonoate D-ring-lactone 和 Limonoic acid di-delta-lactone，化学上属于Furanolactone类化合物。
S2415	Astragaloside A	Astragaloside A是从黄芪中分离的一种纯化的皂苷，广泛应用于治疗心血管疾病。
S2321	Magnolol	Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-KB的激活。
S2322	(+)-Matrine	(+)-Matrine是一种在植物Sophora属中发现的生物碱，具有多种药理作用，包括抗癌作用，是κ阿片受体激动剂。
S3032	Bindarit (AF 2838)	Bindarit (AF 2838) 是天然化合物，具有特定抗炎活性，因为选择性抑制炎症趋化因子亚家族，包括单核细胞趋化蛋白MCP-1/CCL2, MCP-3/CCL7, 和 MCP-2/CCL8。
S2326	Myricetin	Myricetin, 一种具有抗氧化和抗肿瘤活性的天然黄酮，是新型的MEK1抑制剂，抑制JB6 P+小鼠表皮细胞的转化。它还能抑制PI3Kγ，Kd=0.17 μM。
S2327	Myricitrin	Myricitrin (Myricitrine) 是一种化学化合物，可从Myrica cerifera (Bayberry属, 小乔木，原产于北美)的根皮中分离得到。
S2439	Guanosine	Guanosine是一种嘌呤核苷。
S2329	Naringin	Naringin (Naringoside) 是一种黄酮苷，是葡萄柚中的主要的类黄酮，具有柚子汁的苦味。具有抗氧化，降血脂，抗肿瘤活性，并且对cytochrome P450有抑制作用。
S2333	Nobiletin (NSC 76751)	Nobiletin (NSC 76751, Hexamethoxyflavone)是O-甲基黄酮，是从柑橘果皮如橘子分离的一种黄酮类化合物。具有抗炎和抗肿瘤活性。
S2334	Oleanolic Acid	Oleanolic Acid (Caryophyllin)是一种天然存在的三萜类，广泛分布于食用和药用植物，与桦木酸相关，具有相对无毒的，抗肿瘤，保肝，及抗病毒的特性。
S2335	Oridonin (NSC-250682)	Oridonin (Isodonol, Rubescenin, NSC-250682) 是从Rabdosia rubescens中分离的对映贝壳杉烷二萜,是一种具有抗肿瘤、抗细菌和抗感染效果的传统中药。Oridonin 抑制AKT1 和 AKT2的激酶活性，对应的IC50值分别为8.4 μM 和 8.9 μM。
S2336	Orotic acid (6-Carboxyuracil)	Orotic acid (6-Carboxyuracil) 是杂环化合物，是一种酸。
S2337	Osthole	Osthole 是一种香豆素类化合物。
S2338	Oxymatrine	Oxymatrine (Matrine N-oxide)是一种从Sophora flavescens的根部分离的喹唑啉生物碱，具有抗炎症、抗纤维化、抗肿瘤活性，抑制iNOS表达和TGF-β/Smad通路。被用于治疗病毒性肝炎、癌症、病毒性心肌炎、胃肠出血和皮肤疾病。
S2339	Paeonol	Paeonol (Peonol) 是从中草药牡丹皮和Cynanchum paniculatum中提取的主要成分。
S3603	Betulinic acid	Betulinic acid (ALS-357, Lupatic acid, Betulic acid)是一种天然的五环三萜类化合物，具有抗病毒，抗疟药，抗发炎和抗肿瘤的特性。Betulinic acid也是 NF-kB 的活化剂。Phase 1/2
S2341	(-)-Parthenolide	(-)-Parthenolide, Nuclear Factor-κB抑制剂，可特异性地耗尽HDAC1蛋白，而不影响其他I/II类 HDACs。促进MDM2的泛素化并激活p53的细胞功能。
S2343	Phlorizin	Phlorizin (Phloridzin) 是有毒的2'-葡萄糖苷根皮素，属于二氢查尔酮，是一种黄酮类化合物。Phlorizin 是一种非选择性的 SGLT 的抑制剂，对hSGLT1 和 hSGLT2的Ki值分别为300 nM 和 39 nM。Phlorizin 也是 Na+/K+-ATPase 的抑制剂。
S3604	Triptolide (PG490)	Triptolide (PG490, NSC 163062)是一种三环氧二萜类化合物,是从中草药雷公藤中提取的免疫抑制剂。它是一种NF-κB抑制剂，抑制NF-κB转录活性，破坏p65/CBP的相互作用，减少p65蛋白。Triptolide (PG490) 可抑制 heat shock transcription factor 1 (HSF1) 的反式激活。Triptolide 可抑制 MDM2 并通过一个p53非依赖性通路来诱导凋亡。
S2344	Piperine	Piperine (1-Piperoylpiperidine) 是一种生物碱，是造成黑胡椒和长胡椒辛辣的原因，也用于一些传统医学领域，且作为杀虫剂。
S2346	Puerarin	Puerarin (Kakonein) 是一种5-HT2C受体和苯二氮位点拮抗剂。
S2347	Quercetin Dihydrate	Quercetin (Sophoretin) 是一种多酚类黄酮，存在于多种植物性食品中，例如苹果，洋葱，浆果和红酒，由于其神经系统和抗癌作用而被用于许多不同的文化中。Quercetin (Sophoretin) 作为天然类黄酮，是重组SIRT1和PI3K抑制剂的刺激物，对PI3Kγ，PI3Kδ和PI3Kβ的IC50分别为2.4μM，3.0μM和5.4μM。
S2349	Rutaecarpine	Rutaecarpine (Rutecarpine) 是从 Evodia rutaecarpa和相关草药中分离的indolopyridoquinazolinone生物碱。是一种新型的COX2抑制剂。
S2350	Rutin	Rutin (Rutoside)是在许多植物中发现的一种黄酮苷，包括Buckwheat; Tobacco; Forsythia; Hydrangea; Viola, 等。
S2351	Salicin	Salicin (Salicoside, Salicine)是一种醇-β-糖苷，含有D-葡萄糖。是柳树皮产生的一种抗炎剂。它是一种天然的、非选择性的COX1和COX2抑制剂。
S2354	Sclareol	Sclareol 是一种芳香化合物，在Clary sage(Salvia sclarea)中发现而因此命名，被归类为双环二萜醇。
S2355	Sclareolide	Sclareolide (Norambreinolide) 是一种倍半萜内酯天然产物，来源于各种植物，包括Salvia sclarea, Salvia yosgadensis, 和 cigar tobacco。
S2356	Shikimic Acid	Shikimic acid (Shikimate) 通常所知的是其阴离子形式Shikimate，在植物和微生物中，是一种重要的生化中间体。
S2357	Silibinin (NSC 651520)	Silibinin (NSC 651520, Silybin, Silibinin A, Silymarin I, Flavobin)是Silymarin的主要活性成分。
S2358	Silymarin	Silymarin (Silybin B)是一种强效的新型自由基清除剂，用于治疗急性脑梗死患者。
S2359	Sinomenine	Sinomenine (Cucoline, Kukoline) 是一种传统中草药，用于治疗风湿病和关节炎。
S2361	Stigmasterol	Stigmasterol 是一种不饱和植物甾醇，具有抗癌，解热，抗炎和免疫调节作用。
S2362	Synephrine	Synephrine (Oxedrine)是从苦橘及其他柑橘属植物中提取的一种不饱和的植物甾醇，常用于减肥。
S2363	Tangeretin	Tangeretin (Tangeritin)是一种柑橘类黄酮。
S2364	Tanshinone I	Tanshinone I 由丹参分离而来的。
S2365	Tanshinone IIA	Tanshinone IIA (Tanshinone B) 是丹参和Salviae miltiorrhizae Radix中最丰富的二萜醌类，用于治疗心血管疾病和炎症性疾病。是天然的monoacylglycerol lipase抑制剂。
S2366	Taxifolin (Dihydroquercetin)	Taxifolin(Dihydroquercetin)是一种二氢黄酮醇类，是一种黄酮类化合物。是I型VEGFR2 kinase的抑制剂。
S2368	Theobromine	Theobromine (3,7-Dimethylxanthine)是黄嘌呤生物碱，作为一种支气管扩张剂，血管扩张剂。
S2371	Vanillylacetone	Vanillylacetone (NSC 15335) 在化学结构上与其他香料，如Vanillin 和 Eugenol类似，用来作为一种香味味添加剂。Vanillylacetone (Zingerone) 可减轻氧化应激和炎症，下调NF-κB介导的信号通路。Zingerone 充当抗有丝分裂剂，并抑制神经母细胞瘤细胞的生长。
S2372	Xanthone	Xanthone (Genicide)是一种有机化合物，可以由加热水杨酸苯酯制备而得到。
S2373	Yohimbine HCl	Yohimbine (Antagonil) 是一种瞳孔放大剂，用于治疗阳痿，也是一种春药。
E0538	Rhodionin	Fucoxanthin is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities.
S3286	Lycobetaine	Lycobetaine is a quaternary phenanthridinium alkaloid from <i>Lycoris radiata</i> of the Amaryllidaceae family, with significant cytotoxic activity against Lewis lung carcinoma.
S3243	Zeaxanthin	Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye with antioxidant effects.
E0776	Isoneochamaejasmine A	Isoneochamaejasmin A, a biflavonoid isolated from the dried root of <i>Stellera chamaejasme</i> L., is a widely used traditional Chinese medicine.
E2552	Salvigenin	Salvigenin, a natural polyphenolic compound, possesses neuroprotective effect, antitumor cytotoxic and immunomodulatory properties.
E2553	Teucvin	Teucvidin is a diterpenoid from <i>Teucrium</i> species.
E2554	N-Feruloyloctopamine	N-Feruloyloctopamine, an antioxidant constituent, significantly decreases the phosphorylation levels of Akt and p38 MAPK.
E2555	O-AcetylgalanthaMine	O-acetylgalanthamine, one of acetylated alkaloids, is reported for the first time as a natural product isolated from <i>Narcissus pseudonarcissus</i> in 1995.
E2556	Ombuin	Ombuin, an active ingredient isolated from <i>Zanthoxylum armatum</i>, displays broad spectrum antibacterial effect with minimum inhibitory concentrations (MICs) ranges from 125 to 500 μg/mL.
E2557	Prudomestin	Prudomestin, an active ingredient isolated from the heartwood of <i>Prunus domestica</i>, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6 µM).
E2558	Jolkinolide B	Jolkinolide B, a bioactive diterpene isolated from the roots of <i>Euphorbia fischeriana</i> Steud., induces apoptosis in cancer cells.
E2559	N-benzylpentadecanamide	N-benzylpentadecanamide is a member of the N-benzylamides series derived from Maca (<i>Lepidium meyenii</i>).
E2560	Worenine	Worenine, one of the bioactive components isolated from <i>Coptis chinensis</i>, shows dehydrogenization, hydrogenation, hydroxylation and demethylene reactions in phase I metabolism, sulfation and glucuronidation in phase II metabolism in rat.
E2561	Arnicolide C	Arnicolide C, a sesquiterpene lactone isolated <i>Centipeda minima</i>, exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner.
E2562	14-Deoxyandrographolide	14-Deoxyandrographolide, a labdane diterpene with calcium channel blocking activity, desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.
E2563	Deoxyandrographolide	Deoxyandrographolide suppresses LPS induced increase in mRNA levels of iNOS as well as production of proinflammatory mediators TNF-α and IL-6.
E2564	5-O-caffeoylshikimic acid	5-O-Caffeoylshikimic acid can be used in the study for non small cell lung cancer (NSCLC).
E2565	Glabrone	Glabrone, an isoflavone isolated from <i>Glycyrrhiza glabra</i> roots, exhibits anti-influenza and significant PPAR-γ ligand-binding activities.
E2566	2-O-β-D-Glucopyranosyl-L-ascorbic acid	2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG), a bioactive compound isolated from Lycium fruit, is a stable vitamin C analog with anti-tumor activity.
E2567	Lupiwighteone	Lupiwighteone (8-prenylgenistein), an isoflavone present widely in wild-growing plants with antioxidant, antimicrobial and anticancer effects, induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.
E2568	Licoflavone C	Licoflavone C is a prenyl-flavone extracted from <i>Genista ephedroides</i>, reduces the genotoxicity of cancer drugs in human peripheral lymphocytes.
E2569	Tetrahydroepiberberine	Tetrahydroepiberberine, an isoquinoline alkaloid isolated from <i>Corydalis impatiens</i> (Pall.), has antifungal and selective inhibition against the PI-3 virus activities.
E2570	Evocarpine	Evocarpine, a quinolone alkaloid isolated from <i>Evodiae fructus</i>, inhibits Ca<sup>2+</sup> influx through voltage-dependent calcium channels, also possesses antimycobacterial activity.
E2571	rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan	Rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan is a chemical constituent of the fruits of <i>Myristica fragrans</i>.
E2572	Tetrahydrocolumbamine	Tetrahydrocolumbamine ((-)-Isocorypalmine) is a dopamine receptor ligand isolated from the crude base fraction of <i>Corydalis chaerophylla</i>.
E2573	Dihydroevocarpine	Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity.
E2574	Coniferin	Coniferin (Laricin), a glucoside of coniferyl alcohol, inhibits fungal growth and melanization.
E2575	6-Demethoxytangeretin	6-Demethoxytangeretin, a citrus flavonoid isolated from <i>Citrus depressa</i>, exerts anti-inflammatory and anti-allergic activity, and suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways.
E2576	7,3′,4′-Trimethoxyquercetin	3',4',7-Trimethoxyquercetin (Quercetin 3′,4′,7-trimethyl ether), a polymethoxylated flavone isolated from the plant of genus <i>Taraxacum</i>, has antioxidant activity.
E2577	Viscidulin III	Viscidulin III is a natural compound isolated from the roots of <i>Scutellaria viscidula</i> Bge, inhibiting the proliferation of some cancer cell lines.
E2578	12-O-Methylcarnosic acid	12-O-Methylcarnosic acid (12-Methoxycarnosic acid), a diterpene carnosic acid isolated from the acetone extract of <i>Salvia microphylla</i>, is an active constituent of 5α-reductase inhibition with an IC<sup>50</sup> value of 61.7 μM. 12-O-Methylcarnosic acid inhibits proliferation in LNCaP cells. 12-O-Methylcarnosic acid has antioxidant, anti-cancer and antimicrobial activity.
E2579	Calycanthine	Calycanthine, the principal alkaloid of the order Calycanthaceae, has been isolated from a species of the genus <i>Psychotria</i>, and is a central nervous system toxin, causing convulsions.
E2580	Benzo(a)-1,3-benzodioxolo(4,5-g)quinolizinium	Benzo(a)-1,3-benzodioxolo(4,5-g)quinolizinium, 8,9-dimethoxy-6-methyl- is a natural product found in <i>Fumaria capreolata</i>, or <i>Fumaria indica</i>.
E2581	17-Hydroxyisolathyrol	17-Hydroxyisolathyrol is a macrocychc lathyrol derivative isolated from seeds of <i>Euphorbla luthyrrs</i>.
E2582	kamebakaurin	Kamebakaurin is a natural compound isolated from <i>Isodon japonicus</i>. Kamebakaurin is a potent inhibitor of <b>NF-κB</b> activation by directly targeting DNA-binding activity of p50.
E2583	N-Feruloylserotonin	N-Feruloylserotonin ((E/Z)-Moschamine), an antioxidative component and bioactive serotonin derivative, from the Seed of <i>Carthamus tinctorius</i> L., ameliorates atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.
E2584	Licoflavonol	Licoflavonol, a minor flavone from the roots of <i>Glycyrrhiza uralensis</i>, is an inhibitor of the <b>Salmonella type III secretion system (T3SS) </b>.
E2585	Isolicoflavonol	Isolicoflavonol potently inhibits hCES2A (Human carboxylesterase 2)-mediated fluorescein diacetate hydrolysis in a reversible and mixed inhibition manner, with K<sup>i</sup> values less than 1.0 μM.
E2525	Picein	L-picein, a naturally occurring glucoside, acts as a competitive inhibitor of the broad-specificity beta-glucosidase (Ki 0.65 mM) which is a substrate for this enzyme (Km 0.63 mM; Vmax. 277,000 units/mg).
E2526	Phenethyl ferulate	Phenethyl ferulate, a major constituent of Qianghuo, shows inhibitory activities against cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) with IC50s of 4.35 and 5.75 μM, respectively.
E2527	Knidilin	Knidilin (Cnidilin) is isolated from the roots of <i>Angelica dahurica</i>.
E2528	Phellopterin	Phellopterin, a natural product isolated from <i>P. trifoliata</i>, reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
E2529	4',7-Di-O-methylnaringenin	4',7-Di-O-methylnaringenin is a flavonoid found in <i>Renealmia alpinia</i>.
E2530	Isofebrifugin	Isofebrifugine is a natural quinazolinone alkaloid with antimalarial effect.
E2531	Febrifugine	Febrifugine is a quinazolinone alkaloid found in the roots and leaves of <i>Dichroa febrifuga</i>, with antimalarial activity.
E2532	Continentalic acid	Continentalic acid, an active constituent isolated from <i>Aralia continentalis</i>, has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against <i>S. aureus</i>.
E2533	Capsiate	Capsiate, a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.
E2534	Inulicin	Inulicin (1-O-Acetylbritannilactone), an active compound that inhibits VEGF-mediated activation of Src and FAK, inhibits LPS-induced PGE2 production, COX-2 expression, and NF-κB activation and translocation.
E2535	Dihydrocapsiate	Dihydrocapsiate, a compound of capsinoid family, is an orally active TRPV1 agonist, which can be used for the research of metabolism disease.
E2536	Przewaquinone A	Przewaquinone A is a natural product of quinones found in <i>Salvia densiflora</i> and <i>Salvia miltiorrhiza</i> with anti-tumor activity.
E2537	N-trans-Feruloyltyramine	N-trans-Feruloyltyramine (Moupinamide), an alkaloid from <i>Piper nigru</i>, is an inhibitor of COX1 and COX2 with potential antioxidant properties, and possesses anti-inflammatory activity.
E2538	Laurolitsine	Lancifoliaine is a bisbenzylisoquinoline from the bark of <i>Litsea lancifolia</i>.
E2539	Irisolidone	Irisolidone, a major isoflavone found in <i>Pueraria lobata</i> flowers, exhibits potent hepatoprotective activity, also shows the high efficacy for volume-regulated anion channels (VRAC) blockade (IC50=9.8 μM).
E2540	Salvianolic acid F	Salvianolic acid F is a kind of salvianolic acids, which are the most effective and abundant compounds extracted from <i>Salvia miltiorrhiza</i> with good anti-oxidative activity.
E2541	Kumatakenin	Kumatakenin, a flavonoid isolated from cloves, shows the effect of inducing apoptosis in ovarian cancer cells.
E2542	Pilloin	Pilloin, a flavonoid isolated from <i>Marrubium cylleneum</i>, exerts a cytotoxic action targeted at the transformed lymphoblasts, also possesses anti-inflammatory activity.
E2543	Neocryptotanshinone	Neocryptotanshinone, a fatty diterpenoid from <i>Salvia miltiorrhiza</i>, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways.
E2544	Lotusine	Lotusine, a pure alkaloid extracted from the green seed embryo of <i>Nelumbo nucifera</i> Gaertn., shows effect on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.
E2545	3-O-Methylquercetin	3-O-Methylquercetin (3-MQ), a main constituent of <i>Rhamnus nakaharai</i>, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis, with IC50 ranging from 1.6-86.9 μM for PDE isozymes (PDE1-5).
E2546	Homodihydrocapsaicin I	Homodihydrocapsaicin I is a kind of capsaicinoid from the fruits of <i>Capsicum annuum</i>.
E2547	Licoflavone A	Licoflavone A is a flavonoid isolated from the roots of <i>Glycyrrhiza uralensis</i>, inhibits protein tyrosine phosphatase-1B (PTP1B) with an IC50 of 54.5 μM.
E2548	N-(p-Coumaroyl) Serotonin	N-(p-Coumaroyl) Serotonin, a polyphenol isolated from the seeds of safflower, has antioxidative, anti-atherogenic and anti-inflammatory properties.
E2549	(-)-Licarin B	(-)-Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of <i>Myristica fragrans</i>, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway.
E2550	Cheilanthifoline	Cheilanthifoline, an alkaloid isolated from <i>Corydalis calliantha</i>, exhibits antiplasmodial activities against <i>Plasmodium falciparum</i> with IC50s of 0.90 and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively.
E2551	Scoulerin	Scoulerine (Discretamine), an isoquinoline alkaloid, is an inhibitor of BACE1 (ß-site amyloid precursor protein cleaving enzyme 1), also is a potent antimitotic compound which inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells.
E2437	Denudatine	Denudatine is primarily isolated from plants of the genera Aconitum and Delphinium. Denudatine has effects on the action potential of ventricular fibers and inhibits the arrhythmogenic action of aconitine.
E2438	Ginsenoside Rg3	Ginsenoside Rg3 is a natural product found in <i>Panax ginseng</i> and <i>Panax notoginseng</i>. Ginsenoside Rg3 has a role as an apoptosis inducer, an antineoplastic agent, a plant metabolite and an angiogenesis modulating agent.
E2439	4-Hydroxyacetophenone	4-Hydroxyacetophenone (P-hydroxyacetophenone) is a key hepatoprotective and choleretic compound in <i>Artemisia capillaris</i> and <i>A. morrisonensis</i>, also has an anti-hepatitis B virus effect and anti-inflammatory effect.
E2440	Pseudoginsenoside RT5	Pseudoginsenoside RT5 is isolated from <i>Panax quinquefolium</i>.
E2441	Qingyangshengenin	Qingyanshengenin (NSC 379666), a pregnane glycoside, is a C21 steroidal aglycone isolated from the root of <i>Cynanchumot ophyllum</i> (Asclepiadaceae). Qingyanshengenin has anti-cancer activity.
E2442	Ganoderic acid D	Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of <i>Ganoderma lucidum</i>. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells. Ganoderic acid D induces HeLa human cervical carcinoma apoptosis.
E2443	Corynoxine B	Corynoxine B is an oxindole alkaloid isolated from <i>Uncaria rhynchophylla</i> (Miq.) Jacks (Gouteng in Chinese); a Beclin-1-dependent autophagy inducer.
E2444	Neotriptophenolide	Neotriptophenolide is a sesquiterpene pyridine alkaloid isolated from the root barks of <i>Tripterygium hypoglaucum</i>.
E2445	Thonningianin A	Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, <i>Thonningia sanguinea</i>. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation, and metal chelation. Anti-cancer activities.
E2446	Methylophiopogonone A	Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of <i>Ophiopogon japonicas</i>, shows anti-inflammatory activity.
E2447	Guajavarin	Guaijaverin is a <b>urease</b> inhibitor with an IC<sup>50</sup> of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities.
E2448	Demethoxydeacetoxypseudolaric acid B	Demethoxydeacetoxypseudolaric acid B is a metabolite of the glucoside of pseudolaric acid C2 (PC2).
E2449	Eleutheroside A	Eleutheroside A (Daucosterol) is a natural sterolin, displaying the neuroprotective activity.
E2450	Escin IB	Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (<i>Aesculus hippocastanum</i>). Escin IB shows an inhibitory effect on pancreatic lipase activity.
S9847	Methyllycaconitine citrate	Methyllycaconitine citrate is a specific antagonist of <b>α7 neuronal nicotinic acetylcholine receptor (α7nAChR)</b>.
E2451	(+)-peucedanol	(+)-Peusedanol is a coumarin isolated from <i>Peucedanumjaponicum</i>.
E2452	Platycodin D2	Platycodin D2 is a saponin isolated from <i>Platycodon grandiflorum</i>, with anti-cancer activity.
E2453	Rosiridin	Rosiridin inhibits <b>MAO A</b> and <b>MAO B</b> with potential beneficial effect in depression and senile dementia.
E2454	Soyasaponin Aa	Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome prolifer

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