Abbreviation |
Description |
Abl |
V-abl Abelson murine leukemia viral oncogene homolog 1 |
ALK |
anaplastic lymphoma kinase |
ATM |
Ataxia telangiectasia mutated |
B-Raf |
B-Raf proto-oncogene serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma viral oncogene homolog B1 |
Bcl-2 |
B-cell lymphoma 2 |
Bcr |
breakpoint cluster region |
Caspases |
cysteine-aspartic proteases or cysteine-dependent aspartate-directed proteases |
CCR5 |
co-receptors chemokine receptor 5 |
CDK |
Cyclin-dependent kinase |
CFTR potentiator |
Cystic fibrosis transmembrane conductance regulator |
CTSK |
Cathepsin K |
c-Kit |
CD117 (cluster of differentiation 117), also called KIT or C-kit receptor |
c-Met |
mesenchymal-epithelial transition |
DNA-PK |
DNA-dependent protein kinase |
DPP-4 |
Dipeptidyl peptidase-4 |
EGFR |
Epidermal growth factor receptor |
Factor Xa |
Stuart-Prower factor, an enzyme of the coagulation cascade |
FGFR |
Fibroblast growth factor receptor |
FLT-3 |
fms-like tyrosine kinase-3 |
FTS |
Farnesyl thiosalicylic acid |
GSK-3 |
Glycogen synthase kinase 3 |
HER2 |
Human epidermal growth factor receptor 2 |
HDAC |
Histone deacetylase |
HIF |
Hypoxia-inducible factor |
HSP-70 |
heat-shock protein-70 |
HSP-90 |
heat-shock protein-90 |
IGF-1R |
Insulin-like growth factor 1 receptor |
JAK |
Janus kinase |
JNK |
c-Jun N-terminal kinases |
Ksp |
Kinesin spindle protein |
MAPK |
Mitogen-activated Protein Kinase |
MEK |
MAPK/ERK kinase |
mGluRs |
metabotropic glutamate receptors |
mTOR |
Mammalian target of rapamycin |
NF-kB |
Nuclear factor-κB |
p38 MAPK |
p38 Mitogen-activated Protein Kinase |
p53 |
protein 53 or tumor protein 53 |
PARP |
Poly (ADP-ribose) polymerase |
PDGFR |
platelet-derived growth factor receptor |
PDK-1 |
phosphoinositide-dependent kinase-1 |
Rho |
ρ factor |
PI3K |
Phosphatidylinositol 3-kinases |
PKC |
protein kinase C |
PLK |
Polo-like kinase |
Ras |
renin-angiotensin system |
RNAP |
RNA Polymerase or RNApol |
S1PR1 |
Sphingosine-1-phosphate receptor (S1P1) also known as endothelial differentiation gene 1 (EDG1) |
sPLA2 |
Secreted phospholipase A2 |
Src |
Rous sarcoma oncogene cellular homolog |
Stat |
Signal Transducers and Activator of Transcription |
Survivin |
baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5 |
TGF |
Transforming growth factor |
TNF |
Tumor necrosis factor |
VEGFR |
Vascular Endothelial Growth Factor Receptor |
Wnt |
a portmanteau of int and Wg and stands for "Wingless-related integration site" |