| Abbreviation |
Description |
| Abl |
V-abl Abelson murine leukemia viral oncogene homolog 1 |
| ALK |
anaplastic lymphoma kinase |
| ATM |
Ataxia telangiectasia mutated |
| B-Raf |
B-Raf proto-oncogene serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma viral oncogene homolog B1 |
| Bcl-2 |
B-cell lymphoma 2 |
| bcr |
breakpoint cluster region |
| Caspase |
cysteine-aspartic proteases or cysteine-dependent aspartate-directed proteases |
| CCR5 |
co-receptors chemokine receptor 5 |
| CDK |
Cyclin-dependent kinase |
| CFTR potentiator |
Cystic fibrosis transmembrane conductance regulator |
| CTSK |
Cathepsin K, abbreviated CTSK |
| c-Kit |
CD117, also called KIT or C-kit receptor |
| c-Met |
mesenchymal-epithelial transition factor |
| DNA-PK |
DNA-dependent protein kinase |
| DPP-4 |
Dipeptidyl peptidase-4 |
| EGFR |
Epidermal growth factor receptor |
| Factor Xa |
also known by the eponym Stuart-Prower factor or as prothrombinase |
| FGFR |
Fibroblast growth factor receptor |
| FLT-3 |
fms-like tyrosine kinase receptor-3 |
| FTS |
farnesyl thiosalicylic |
| GSK-3 |
Glycogen synthase kinase 3 |
| HER2 |
Human Epidermal growth factor Receptor 2 |
| Hedgehog |
an intercellular signaling molecule called Hedgehog (Hh) |
| HDAC |
Histone deacetylase |
| HIF |
Hypoxia-inducible factor |
| HSP-70 |
heat-shock protein-70 |
| HSP-90 |
heat-shock protein-90 |
| IGF-1R |
Insulin-like growth factor 1 receptor |
| JAK |
Janus kinase |
| JNK |
c-Jun N-terminal kinases |
| Ksp |
Kinesin spindle protein |
| MAPK |
Mitogen-activated Protein Kinase |
| MEK |
MAPK/ERK kinase |
| mGlu2/3 receptors |
metabotropic glutamate receptors |
| mTOR |
Mammalian target of rapamycin |
| NF-kB |
Nuclear factor κ B |
| p38 MAPK |
p38 Mitogen-activated Protein Kinase |
| p53 |
protein 53 or tumor protein 53 |
| PARP |
Poly (ADP-ribose) polymerase |
| PDGFR |
platelet-derived growth factor receptor |
| PDK-1 |
phosphoinositide-dependent kinase-1 |
| Rho |
ρ factor |
| PI3K |
Phosphatidylinositol 3-kinases |
| PKC |
protein kinase C |
| PLK |
Polo-like kinase |
| Ras |
renin-angiotensin system |
| RNA Polymerase I |
RNAP or RNApol |
| S1PR1 |
sphingosine-1-phosphate receptor 1，also known as S1P1 or EDG1 (endothelial differentiation gene 1) |
| sPLA2 |
Secreted phospholipases A2 |
| Src |
Rous sarcoma oncogene cellular homolog |
| Stat |
Signal Transducers and Activator of Transcription |
| Survivin |
also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5 |
| TGF-beta |
Transforming growth factor |
| TNF-alpha |
Tumor necrosis factors |
| VEGFR-PDGFR |
Vascular Endothelial Growth Factor Receptor -platelet derived growth factor receptor |
| Wee1 |
Small cell protein, a mitotic inhibitor kinase |
| Wnt |
a combination of Wg (wingless) and Int |
