| 目录号 |
产品目录 |
产品描述 |
| S9321 |
Topotecan |
|
| S4021 |
Tolcapone |
Tolcapone是一种有效和选择性的可逆硝基酚类儿茶酚-O-甲基转移酶(COMT)抑制剂，Ki为30nM。 |
| S4589 |
Amodiaquine dihydrochloride dihydrate |
Amodiaquine在人红细胞中是一种有效的、非竞争性的组胺N-甲基转移酶抑制剂，其Ki值为18.6 nM。它也被用作抗疟疾药和消炎药。 |
| S4635 |
Cyproheptadine hydrochloride |
Cyproheptadine hydrochloride是非选择性的5HT2拮抗剂，其IC50为0.6 nM。它同时还是一个SETD7/9的抑制剂。 |
| S3639 |
Tacrine hydrochloride hydrate |
Tacrine是胆碱酯酶（cholinesterase）抑制剂，可对抗骨骼肌松弛药的作用，可作为呼吸兴奋剂并用于治疗阿兹海默病和其他中枢神经系统障碍。它也是组胺N-甲基转移酶（histamine N-methyltransferase）
|
| S3147 |
Entacapone |
Entacapone抑制儿茶酚-O-甲基转移酶(COMT)活性，IC50为151 nM。 |
| S4245 |
Sodium ascorbate |
Sodium ascorbate作为抗氧化剂和酸度调节剂，在消除慢性和急性感染方面发挥重要作用。 |
| S1026 |
Imatinib Mesylate (STI571) |
Imatinib Mesylate (STI571)是一种口服生物有效的Imatinib甲磺酸盐，是一种多靶点抑制剂，作用于v-Abl，c-Kit和PDGFR，在无细胞和细胞试验中，IC50分别为0.6 μM，0.1 μM 和0.1 μM。 |
| S1011 |
Afatinib (BIBW2992) |
Afatinib (BIBW2992)不可逆地抑制EGFR/ErbB，包括EGFR(wt)，EGFR(L858R)，EGFR(L858R/T790M)，ErbB2（HER2）和ErbB4（HER4），在无细胞试验中IC50分别为0.5 nM，0.4 nM，10 nM，14 nM和1 nM。 |
| S5077 |
Regorafenib Monohydrate |
Regorafenib是一种新型口服的多重激酶抑制剂，对VEGFR1、小鼠VEGFR2、小鼠VEGFR3、PDGFR-β、KIT、RET、RAF-1、B-RAF和B-RAF(V600E)的IC50分别为13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM。 |
| S1311 |
Pamidronate Disodium |
Pamidronate Disodium 为含氮的双磷酸盐类药物，用于预防骨质疏松症。 |
| S5739 |
Nebivolol |
Nebivolol is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure. |
| S5741 |
Quetiapine |
Quetiapine is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. |
| S1791 |
Bacitracin Zinc |
Bacitracin是一种抗生素，能够干扰C55-isoprenyl pyrophosphate的去磷酸化，C55-isoprenyl pyrophosphate是一种膜载体分子，参与转运构成肽聚糖细菌细胞壁内膜外部成分。Bacitracin抑制甲硫啡肽中Tyr的裂解，IC50为10 μM。 |
| S5206 |
Benzylpenicillin potassium |
Benzylpenicillin potassium是青霉素G的钾盐形式，青霉素G是广谱的青霉素抗生素。 |
| S5476 |
Rolapitant |
Rolapitant is a selective and competitive antagonist of human substance P/NK1 receptors with antiemetic activity. It has a high affinity for the human NK1 receptor of 0.66 nM and high selectivity over the human NK2 and NK3 subtypes of >1000-fold, as well as preferential affinity for human, guinea pig, gerbil and monkey NK1 receptors over rat, mouse and rabbit. |
| S5719 |
Ceftizoxime sodium |
Ceftizoxime sodium is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. |
| S4692 |
Succimer |
Succimer (DMSA) is an orally active metal chelator is used to treat heavy metal poisoning. |
| S5656 |
Diphenylpyraline hydrochloride |
Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline, which is an antihistamine used in the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| S5301 |
Carglumic Acid |
Carglumic Acid is an orally active, synthetic structural analogue of N-acetylglutamate (NAG) and carbamoyl phosphate synthetase 1 (CPS 1) activator, with ammonia lowering activity. |
