激酶药物库 (Kinase Inhibitor Library)

目录号 L1200

1188种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选。

规格

价格

预溶于DMSO或水
100uL/well (2mM or 10mM solution)	RMB 160058.14
2x100uL/well (2mM or 10mM solution)	RMB 245225.12

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分/子/库/可/定/制:

特定分子选择规格分子所置板上位置粉末或DMSO溶液

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Kinase Inhibitor Library目录

点击下载Kinase Inhibitor Library - XLSX

点击下载Kinase Inhibitor Library - SDF

客户使用该分子库发表的文献65篇：

Nat Med,2017,23(4):405-408

PubMed: 28388612 ( click the link to review the publication )

Gastroenterology,2017,153(5):1429-1443

PubMed: 28764929 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Nat Commun,2019,10(1):2197

PubMed: 31097693 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

NPJ Genom Med,2019,4:7

PubMed: 30962949 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

J Exp Clin Cancer Res,2019,38(1):56

PubMed: 30728057 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Development,2019,146(14)

PubMed: 31142539 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Anal Biochem,2019,569:46-52

PubMed: 30707898 ( click the link to review the publication )

Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

Methods Mol Biol,2019,1888:115-126

PubMed: 30519943 ( click the link to review the publication )

Methods Mol Biol,2019,1888:21-43

PubMed: 30519939 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

Mol Cancer Ther,2018,10.1158/1535-7163.MCT-18-0179

PubMed: 30523050 ( click the link to review the publication )

Stem Cell Res Ther,2018,9(1):319

PubMed: 30463599 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

Antimicrob Agents Chemother,2018,10.1128/AAC.01744-18

PubMed: 30455231 ( click the link to review the publication )

Hum Gene Ther,2018,29(8):886-901

PubMed: 29641320 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )
Cell Stress,2018,10.15698/cst2018.04.131

PubMed: ( click the link to review the publication )

FEBS Open Bio,2018,9(1):82-91

PubMed: 30652076 ( click the link to review the publication )

Antiviral Res,2018,158:226-237

PubMed: 30149038 ( click the link to review the publication )

Nat Commun,2017,8:15289

PubMed: 28474672 ( click the link to review the publication )

Cell Rep,2017,21(9):2639-2646

PubMed: 29186697 ( click the link to review the publication )

Cancer Lett,2017,405:73-78

PubMed: 28756008 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

J Mol Biol,2017,429(13):2042-2045

PubMed: 28137420 ( click the link to review the publication )

Biochim Biophys Acta,2017,1861(4):947-957

PubMed: 28161478 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,62(1)

PubMed: 29061736 ( click the link to review the publication )

J Biol Chem,2017,292(41):17037-17045

PubMed: 28821610 ( click the link to review the publication )

Front Plant Sci,2017, 10.3389/fpls.2017.00852.

PubMed: 28603531 ( click the link to review the publication )

ChemMedChem,2017,12(22):1857-1865

PubMed: 28952188 ( click the link to review the publication )

Biochem Biophys Res Commun,2017,493(1):58-63

PubMed: 28919416 ( click the link to review the publication )

J Mol Cell Cardiol,2016,97:106-13

PubMed: 27130278 ( click the link to review the publication )

Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

ChemMedChem,2016,11(11):1137-44

PubMed: 27135311 ( click the link to review the publication )

ChemMedChem,2016,10.1002/cmdc

PubMed: 27472906 ( click the link to review the publication )

Bioorg Med Chem,2016,24(19):4647-51

PubMed: 27519462 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

J Control Release,2015,204:20-9

PubMed: 25681050 ( click the link to review the publication )
Oncogene,2015,34(32):4199-210

PubMed: 25362855 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Breast Cancer Res Treat,2015,149(3):715-26

PubMed: 25667100 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

BMC Cancer,2015,15:239

PubMed: 25885472 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Mol Cancer Ther,2014,13(2):353-63

PubMed: 24398428 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

ACS Chem Biol,2014,9(5):1160-71

PubMed: 24568369 ( click the link to review the publication )

PLoS One,2014,9(7):e102741

PubMed: 25048812 ( click the link to review the publication )

Mol Med Rep,2014,10(6):3348-56

PubMed: 25323421 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

PLoS One,2013,8(5):e63240

PubMed: 23667592 ( click the link to review the publication )

PLoS One,2013,8(4):e60334

PubMed: 23593196 ( click the link to review the publication )

描述及优势

•1188种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选

•作用于激酶，如EGFR、PI3K、Aurora激酶、CDK和MEK

•其中一些激酶抑制剂已得到FDA批准

•大部分为ATP竞争性抑制剂

•结构多样，药效显著，可渗透细胞

•具有充分详细的结构说明及客户反馈资料

•NMR和HPLC技术保证产品高纯度

详细信息

配制:	1137个化合物预溶于10mM DMSO，12个化合物预溶于10mM水，39个化合物预溶于2mM DMSO
容器:	带有螺旋盖和二维码的96孔储存管
储存条件:	1年 -20°C溶于DMSO
储存条件:	2年 -80°C溶于DMSO
发货:	干冰或蓝冰物流
包装:	惰性气体

Kinase Inhibitor Library组成

HTS Facility Partners

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研究领域

产品类型