激酶药物库 (Kinase Inhibitor Library)

目录号 L1200

1234种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选。

规格

价格

预溶于DMSO或水
100uL/well (2mM or 10mM solution)	RMB 166257.91
2x100uL/well (2mM or 10mM solution)	RMB 254717.68

询价/订购，请联系我们

全国免费电话：400-668-6834 | Email：info@selleck.cn

分/子/库/可/定/制:

特定分子选择规格分子所置板上位置粉末或DMSO溶液

定制您的分子库

Kinase Inhibitor Library目录

点击下载Kinase Inhibitor Library - SDF

点击下载Kinase Inhibitor Library - XLSX

客户使用该分子库发表的文献75篇：

Nat Med,2017,23(4):405-408

PubMed: 28388612 ( click the link to review the publication )

Gastroenterology,2017,153(5):1429-1443

PubMed: 28764929 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Nat Commun,2019,10(1):2197

PubMed: 31097693 ( click the link to review the publication )

Sci Adv,2019,5(5):eaav2249

PubMed: 31106268 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

Clin Cancer Res,2019,25(14):4530-4541

PubMed: 30940655 ( click the link to review the publication )

NPJ Genom Med,2019,4:7

PubMed: 30962949 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

J Exp Clin Cancer Res,2019,38(1):56

PubMed: 30728057 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):77

PubMed: 31262335 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Development,2019,146(14)

PubMed: 31142539 ( click the link to review the publication )

Cell Chem Biol,2019,26(5):765-777

PubMed: 30956147 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Biochem Pharmacol,2019,169:113640

PubMed: 31536726 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,178(2):263-274

PubMed: 31388935 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Eur J Pharm Sci,2019,10.1016/j.ejps.2019.105088

PubMed: 31626963 ( click the link to review the publication )

Exp Gerontol,2019,126:110691

PubMed: 31421186 ( click the link to review the publication )

Anal Biochem,2019,569:46-52

PubMed: 30707898 ( click the link to review the publication )

Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )
Methods Mol Biol,2019,1888:21-43

PubMed: 30519939 ( click the link to review the publication )

Methods Mol Biol,2019,1888:115-126

PubMed: 30519943 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

Mol Cancer Ther,2018,10.1158/1535-7163.MCT-18-0179

PubMed: 30523050 ( click the link to review the publication )

Stem Cell Res Ther,2018,9(1):319

PubMed: 30463599 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )

Antimicrob Agents Chemother,2018,10.1128/AAC.01744-18

PubMed: 30455231 ( click the link to review the publication )

Hum Gene Ther,2018,29(8):886-901

PubMed: 29641320 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

Cell Stress,2018,10.15698/cst2018.04.131

PubMed: ( click the link to review the publication )

FEBS Open Bio,2018,9(1):82-91

PubMed: 30652076 ( click the link to review the publication )

Antiviral Res,2018,158:226-237

PubMed: 30149038 ( click the link to review the publication )

Nat Commun,2017,8:15289

PubMed: 28474672 ( click the link to review the publication )

Cell Rep,2017,21(9):2639-2646

PubMed: 29186697 ( click the link to review the publication )

Cancer Lett,2017,405:73-78

PubMed: 28756008 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

J Mol Biol,2017,429(13):2042-2045

PubMed: 28137420 ( click the link to review the publication )

Biochim Biophys Acta,2017,1861(4):947-957

PubMed: 28161478 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,62(1)

PubMed: 29061736 ( click the link to review the publication )

J Biol Chem,2017,292(41):17037-17045

PubMed: 28821610 ( click the link to review the publication )

Front Plant Sci,2017, 10.3389/fpls.2017.00852.

PubMed: 28603531 ( click the link to review the publication )

ChemMedChem,2017,12(22):1857-1865

PubMed: 28952188 ( click the link to review the publication )

Biochem Biophys Res Commun,2017,493(1):58-63

PubMed: 28919416 ( click the link to review the publication )
J Mol Cell Cardiol,2016,97:106-13

PubMed: 27130278 ( click the link to review the publication )

Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

ChemMedChem,2016,11(11):1137-44

PubMed: 27135311 ( click the link to review the publication )

ChemMedChem,2016,10.1002/cmdc

PubMed: 27472906 ( click the link to review the publication )

Bioorg Med Chem,2016,24(19):4647-51

PubMed: 27519462 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

J Control Release,2015,204:20-9

PubMed: 25681050 ( click the link to review the publication )

Oncogene,2015,34(32):4199-210

PubMed: 25362855 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Breast Cancer Res Treat,2015,149(3):715-26

PubMed: 25667100 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

BMC Cancer,2015,15:239

PubMed: 25885472 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Mol Cancer Ther,2014,13(2):353-63

PubMed: 24398428 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

ACS Chem Biol,2014,9(5):1160-71

PubMed: 24568369 ( click the link to review the publication )

PLoS One,2014,9(7):e102741

PubMed: 25048812 ( click the link to review the publication )

Mol Med Rep,2014,10(6):3348-56

PubMed: 25323421 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )
Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

PLoS One,2013,8(5):e63240

PubMed: 23667592 ( click the link to review the publication )

PLoS One,2013,8(4):e60334

PubMed: 23593196 ( click the link to review the publication )

描述及优势

•1234种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选

•作用于激酶，如EGFR、PI3K、Aurora激酶、CDK和MEK

•其中一些激酶抑制剂已得到FDA批准

•大部分为ATP竞争性抑制剂

•结构多样，药效显著，可渗透细胞

•具有充分详细的结构说明及客户反馈资料

•NMR和HPLC技术保证产品高纯度

详细信息

配制:	1180个化合物预溶于10mM DMSO，13个化合物预溶于10mM水，41个化合物预溶于2mM DMSO
容器:	带有螺旋盖和二维码的96孔储存管
储存条件:	1年 -20°C溶于DMSO
储存条件:	2年 -80°C溶于DMSO
发货:	干冰或蓝冰物流
包装:	惰性气体

Kinase Inhibitor Library组成

HTS Facility Partners

查看其他分子库

FDA-approved Drug Library

2572种获得上市批准的原料药的独特集合，可用于高通量筛选和高内涵筛选。
Drug Repurposing Library

2829种已经上市或通过临床I期的药物集合，可用于高通量筛选(HTS)和高内涵筛选(HCS)。
Preclinical and Clinical Compound Library

提供2569种临床前和临床药物，可用于高通量筛选和高内涵筛选。
Bioactive Compound Library-I

6836种具有生物活性的化合物的独特集合，可用于高通量筛选和高内涵筛选。
Bioactive Compound Library-Ⅱ

5309种具有生物活性的化合物的独特集合，可用于高通量筛选和高内涵筛选。
Express-Pick Library

具有不同的核心结构的4208种化合物的独特集合，适用于高通量筛选（HTS）和高含量筛选（HCS）。
Natural Product Library

2054种天然产物的独特集合，可用于高通量筛选和高内涵筛选。
Human Endogenous Metabolite Compound Library

提供408种人类内源代谢物小分子集合，涉及多个代谢通路，可用于高通量筛选和高内涵筛选，为人类开辟肿瘤等多种疾病治疗的新途径
Angiogenesis Related compound Library

用于血管生成研究的113种小分子的独特集合，靶向Bcr-Abl，BTK，HIF，VEGFR，FGFR，FAK等。
Anti-alzheimer's Disease Compound Library

用于探索阿尔茨海默病机制的487种小分子的独特集合。
Antibiotics compound Library

308种抗生素的独特集合，可用于鉴定药物靶标并探索治疗人类疾病的新机制和方法。
Anti-cancer Compound Library

针对多种癌症：乳腺癌，白血病，肺癌，淋巴瘤等的1933种抗癌化合物的独特集合
Anti-cancer Metabolism Compound Library

用于癌症代谢研究的195种小分子的独特集合。
Anti-diabetic Compound Library

提供152种与糖尿病发展相关的化合物集合，可用于糖尿病学的研究。
Anti-infection Compound Library

930种抗感染化合物的独特集合，具有抗细菌，抗真菌，抗病毒等生物活性。
Apoptosis Compound Library

提供693种凋亡相关化合物集合，靶向作用于Bcl-2,Caspase,p53,TNF-alpha,Mdm2,survin等，可用于高通量筛选和高内涵筛选。
Autophagy Compound Library

提供822种自噬化合物集合，这些药物同自噬诱发的相关通路关联，可用于高通量筛选和高内涵筛选。
Cambridge Cancer Compound Library

与麻省理工学院Koch研究所的研究人员合作而获得的一个高附加值的分子库，提供247种抗癌化合物的独特集合。
Cell Cycle compound library

120种小分子化合物的独特集合，用于研究细胞周期和相关疾病。
CNS-Penetrant Compound Library

307个独特的血脑屏障通透化合物集合，具有生物活性，可用于神经系统研究。
Covalent Inhibitor Library

81种共价抑制剂的独特集合，用于高通量筛选（HTS）和高含量筛选（HCS）。
DNA Damage/DNA Repair compound Library

用于DNA损伤和修复研究的179种小分子的独特集合，靶向PARP，ATM / ATR，拓扑异构酶，DNA / RNA合成等。
Epigenetics Compound Library

具有生物活性的470种化合物的独特集合，用于表观遗传学研究和相关分析
Fragment Library

提供1015种片段小分子集合，可用于基于片段的新药发现(FBDD)
GPCR Compound Library

提供739种靶向G蛋白偶联受体的小分子，可用于高通量筛选和高内涵筛选。
HIF-1 Signaling Pathway Compound Library

449种HIF-1信号通路化合物的集合，可用于细胞氧感知相关研究。
Highly Selective Inhibitor Library

提供320种高选择性抑制剂药物集合，涵盖123个靶点，可用于高通量筛选和高内涵筛选。
Histone modification compound library

112种具有生物活性的小分子的独特集合，用于组蛋白修饰研究和相关分析。
HTS Library for Drug Discovery

提供99040种化合物，类药性强，结构多样，可用于高通量筛选和高内涵筛选。
Immunology/Inflammation Compound Library

提供1057种免疫/炎症相关化合物集合，可用于高通量筛选和高内涵筛选。
Inhibitor Library

2774种抑制剂的独特集合，可用于高通量筛选和高内涵筛选。
Ion Channel Ligand Library

提供232种离子通道配体化合物集合，可用于多种类型离子通道实验研究。
JAK/STAT compound library

50个小分子的独特集合，用于研究JAK-STAT信号通路
MAPK Inhibitor Library

提供94种MAPK抑制剂药物集合，可用于MAPK信号通路实验研究。
Metabolism Compound Library

提供1367种代谢相关的小分子集合，涉及多个代谢通路，可用于高通量筛选和高内涵筛选。
Neuronal Signaling Compound Library

提供1098种具有生物活性的小分子化合物集合，用于神经信号学相关的高通量筛选和高内涵筛选。
NF-κB Signaling Compound Library

40种小分子的独特集合，可用于在免疫/炎症和癌症中起关键作用的NF-κB信号通路研究。
PI3K/Akt Inhibitor Library

提供173种PI3K/Akt 抑制剂集合，可用于PI3K/Akt/mTOR 信号通路实验研究。
Protease Inhibitor Library

提供227种蛋白酶抑制剂药物集合，可用于化学基因组学、高通量筛选和高内涵筛选。
Small Molecule Immuno-Oncology Compound Library

90种免疫肿瘤小分子的独特集合，用于与其他药物联合的肿瘤治疗。
Stem Cell Signaling Compound Library

298种干细胞小分子化合物的独特集合，具有生物活性，用于干细胞调节和信号转导通路研究。
TGF-beta/Smad compound library

60种具有生物活性的小分子的独特集合，用于TGF-β/ Smad信号通路研究。
Tyrosine Kinase Inhibitor Library

提供394种酪氨酸激酶抑制剂的集合，可用于高通量筛选和高内涵筛选。
Ubiquitination Compound Library

151个小分子的独特集合，用于泛素化相关研究。

研究领域

产品类型