激酶药物库 (Kinase Inhibitor Library)

目录号 L1200

1255种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选。

规格

价格

预溶于DMSO或水
100uL/well (2mM or 10mM solution)	RMB 169082.94
2x100uL/well (2mM or 10mM solution)	RMB 259049.96

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全国免费电话：400-668-6834 | Email：info@selleck.cn

分/子/库/可/定/制:

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Kinase Inhibitor Library目录

点击下载Kinase Inhibitor Library - SDF

点击下载Kinase Inhibitor Library - XLSX

客户使用该分子库发表的文献101篇：

Nat Med,2017,23(4):405-408

PubMed: 28388612 ( click the link to review the publication )

Cancer Cell,2017,32(5):684-700

PubMed: 29107533 ( click the link to review the publication )

Gastroenterology,2017,153(5):1429-1443

PubMed: 28764929 ( click the link to review the publication )

Cancer Cell,2015,28(2):240-52

PubMed: 26267537 ( click the link to review the publication )

Nat Med,2014,20(8):954-60

PubMed: 24997607 ( click the link to review the publication )

Eur J Immunol,2020,50(1):73-85

PubMed: 31621069 ( click the link to review the publication )

Genome Biol,2019,20(1):253

PubMed: 31771620 ( click the link to review the publication )

Nat Commun,2019,10(1):2197

PubMed: 31097693 ( click the link to review the publication )

Nat Commun,2019,10(1):5444

PubMed: 31784510 ( click the link to review the publication )

Sci Adv,2019,5(5):eaav2249

PubMed: 31106268 ( click the link to review the publication )

Sci Adv,2019,5(6):eaav9784

PubMed: 31249867 ( click the link to review the publication )

Clin Cancer Res,2019,25(14):4530-4541

PubMed: 30940655 ( click the link to review the publication )

Proc Natl Acad Sci U S A,2019,116(39):19541-19551

PubMed: 31501330 ( click the link to review the publication )

NPJ Genom Med,2019,4:7

PubMed: 30962949 ( click the link to review the publication )

Neuropsychopharmacology,2019,10.1038/s41386-018-0266-7

PubMed: 30518933 ( click the link to review the publication )

J Exp Clin Cancer Res,2019,38(1):56

PubMed: 30728057 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):77

PubMed: 31262335 ( click the link to review the publication )

Breast Cancer Res,2019,21(1):37

PubMed: 30845991 ( click the link to review the publication )

Development,2019,146(14)

PubMed: 31142539 ( click the link to review the publication )

Cell Chem Biol,2019,26(5):765-777

PubMed: 30956147 ( click the link to review the publication )

ACS Infect Dis,2019,5(10):1764-1771

PubMed: 31434474 ( click the link to review the publication )

Neurobiol Aging,2019,76:24-34

PubMed: 30640040 ( click the link to review the publication )

Biochem Pharmacol,2019,169:113640

PubMed: 31536726 ( click the link to review the publication )

Sci Rep,2019,9(1):13308

PubMed: 31527768 ( click the link to review the publication )
Sci Rep,2019,9(1):16452

PubMed: 31712618 ( click the link to review the publication )

Cancer Gene Ther,2019,10.1038/s41417-019-0127-5

PubMed: 31383953 ( click the link to review the publication )

J Biol Chem,2019,294(47):17941-17950

PubMed: 31597699 ( click the link to review the publication )

Stem Cells Int,2019,2019:3435901

PubMed: 31871467 ( click the link to review the publication )

Biochem J,2019,476(21):3197-3209

PubMed: 31652302 ( click the link to review the publication )

Cancer Manag Res,2019,11:8391-8405

PubMed: 31571995 ( click the link to review the publication )

Breast Cancer Res Treat,2019,178(2):263-274

PubMed: 31388935 ( click the link to review the publication )

Breast Cancer Res Treat,2019,10.1007/s10549-019-05504-5

PubMed: 31784862 ( click the link to review the publication )

Acta Pharmacol Sin,2019,10.1038/s41401-019-0246-4

PubMed: 31197246 ( click the link to review the publication )

Cell Signal,2019,67:109508

PubMed: 31866490 ( click the link to review the publication )

Eur J Pharm Sci,2019,10.1016/j.ejps.2019.105088

PubMed: 31626963 ( click the link to review the publication )

Virology,2019,541:41-51

PubMed: 31826845 ( click the link to review the publication )

BMC Cancer,2019,19(1):936

PubMed: 31601188 ( click the link to review the publication )

Exp Gerontol,2019,126:110691

PubMed: 31421186 ( click the link to review the publication )

J Bone Oncol,2019,19:100268

PubMed: 31832331 ( click the link to review the publication )

Anal Biochem,2019,569:46-52

PubMed: 30707898 ( click the link to review the publication )

Bioengineered,2019,10(1):98-107

PubMed: 31023186 ( click the link to review the publication )

Kaohsiung J Med Sci,2019,10.1002/kjm2.12051

PubMed: 30896891 ( click the link to review the publication )

Methods Mol Biol,2019,1888:21-43

PubMed: 30519939 ( click the link to review the publication )

Methods Mol Biol,2019,1888:115-126

PubMed: 30519943 ( click the link to review the publication )

Cell Rep,2018,22(5):1185-1199

PubMed: 29386107 ( click the link to review the publication )

Mol Cancer Ther,2018,10.1158/1535-7163.MCT-18-0179

PubMed: 30523050 ( click the link to review the publication )

Stem Cell Res Ther,2018,9(1):319

PubMed: 30463599 ( click the link to review the publication )

Cancer Sci,2018,109(4):1220-1229

PubMed: 29453896 ( click the link to review the publication )
Antimicrob Agents Chemother,2018,10.1128/AAC.01744-18

PubMed: 30455231 ( click the link to review the publication )

Hum Gene Ther,2018,29(8):886-901

PubMed: 29641320 ( click the link to review the publication )

Sci Rep,2018,8(1):3521

PubMed: 29476067 ( click the link to review the publication )

Sci Rep,2018,8(1):14800

PubMed: 30287839 ( click the link to review the publication )

Sci Rep,2018,8(1):13106

PubMed: 30166612 ( click the link to review the publication )

J Cell Physiol,2018,233(1):422-433

PubMed: 28294327 ( click the link to review the publication )

Cell Stress,2018,10.15698/cst2018.04.131

PubMed: ( click the link to review the publication )

FEBS Open Bio,2018,9(1):82-91

PubMed: 30652076 ( click the link to review the publication )

Antiviral Res,2018,158:226-237

PubMed: 30149038 ( click the link to review the publication )

Biomedical Sciences,2018,December, 2018

PubMed: no ( click the link to review the publication )

Oncotarget,2018,9(57):31018-31031

PubMed: 30123424 ( click the link to review the publication )

Nat Commun,2017,8:15289

PubMed: 28474672 ( click the link to review the publication )

Nat Chem Biol,2017,13(6):616-623

PubMed: 28346404 ( click the link to review the publication )

Cell Rep,2017,21(9):2639-2646

PubMed: 29186697 ( click the link to review the publication )

Cancer Lett,2017,405:73-78

PubMed: 28756008 ( click the link to review the publication )

Anal Chem,2017,89(12):6678-6685

PubMed: 28520400 ( click the link to review the publication )

J Mol Biol,2017,429(13):2042-2045

PubMed: 28137420 ( click the link to review the publication )

Biochim Biophys Acta,2017,1861(4):947-957

PubMed: 28161478 ( click the link to review the publication )

Antimicrob Agents Chemother,2017,62(1)

PubMed: 29061736 ( click the link to review the publication )

J Biol Chem,2017,292(41):17037-17045

PubMed: 28821610 ( click the link to review the publication )

Front Plant Sci,2017, 10.3389/fpls.2017.00852.

PubMed: 28603531 ( click the link to review the publication )

ChemMedChem,2017,12(22):1857-1865

PubMed: 28952188 ( click the link to review the publication )

Biochem Biophys Res Commun,2017,493(1):58-63

PubMed: 28919416 ( click the link to review the publication )

J Mol Cell Cardiol,2016,97:106-13

PubMed: 27130278 ( click the link to review the publication )
Pharmacol Res,2016,113(Pt A):216-227

PubMed: 27543462 ( click the link to review the publication )

ChemMedChem,2016,10.1002/cmdc

PubMed: 27472906 ( click the link to review the publication )

ChemMedChem,2016,11(11):1137-44

PubMed: 27135311 ( click the link to review the publication )

Bioorg Med Chem,2016,24(19):4647-51

PubMed: 27519462 ( click the link to review the publication )

PLoS One,2016,11(2):e0149848

PubMed: 26919709 ( click the link to review the publication )

Sensors (Basel),2016,16(3)

PubMed: 26999137 ( click the link to review the publication )

Clin Cancer Res,2015,21(5):1172-82

PubMed: 25549722 ( click the link to review the publication )

Biosens Bioelectron,2015,68:699-704

PubMed: 25668591 ( click the link to review the publication )

J Control Release,2015,204:20-9

PubMed: 25681050 ( click the link to review the publication )

Oncogene,2015,34(32):4199-210

PubMed: 25362855 ( click the link to review the publication )

Mol Cancer Ther,2015,14(5):1213-23

PubMed: 25777964 ( click the link to review the publication )

Biochim Biophys Acta,2015,10.1016/j.bbapap.2015.04.023

PubMed: 25936777 ( click the link to review the publication )

Breast Cancer Res Treat,2015,149(3):715-26

PubMed: 25667100 ( click the link to review the publication )

Cell Cycle,2015,14(1):109-22

PubMed: 25602521 ( click the link to review the publication )

BMC Cancer,2015,15:239

PubMed: 25885472 ( click the link to review the publication )

PLoS One,2015,10(2):e0118346

PubMed: 25706943 ( click the link to review the publication )

PLoS One,2015,10(11):e0142655

PubMed: 26569102 ( click the link to review the publication )

Biochem Biophys Res Commun,2015,463(4):888-93

PubMed: 26056008 ( click the link to review the publication )

Oncotarget,2015,6(3):1531-43

PubMed: 25605238 ( click the link to review the publication )

Head Neck,2015,37(12):1722-32

PubMed: 24986420 ( click the link to review the publication )

Mol Cancer Ther,2014,13(2):353-63

PubMed: 24398428 ( click the link to review the publication )

Mol Cancer Res,2014,12(5):703-13

PubMed: 24554781 ( click the link to review the publication )

ACS Chem Biol,2014,9(5):1160-71

PubMed: 24568369 ( click the link to review the publication )

PLoS One,2014,9(7):e102741

PubMed: 25048812 ( click the link to review the publication )
Mol Med Rep,2014,10(6):3348-56

PubMed: 25323421 ( click the link to review the publication )

Oncotarget,2014,5(15):6512-25

PubMed: 25156567 ( click the link to review the publication )

Curr Protoc Chem Biol,2014,4:177-191

PubMed: 26705509 ( click the link to review the publication )

PLoS One,2013,8(4):e60334

PubMed: 23593196 ( click the link to review the publication )

PLoS One,2013,8(5):e63240

PubMed: 23667592 ( click the link to review the publication )

描述及优势

•1255种激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选

•作用于激酶，如EGFR、PI3K、Aurora激酶、CDK和MEK

•其中一些激酶抑制剂已得到FDA批准

•大部分为ATP竞争性抑制剂

•结构多样，药效显著，可渗透细胞

•具有充分详细的结构说明及客户反馈资料

•NMR和HPLC技术保证产品高纯度

详细信息

配制:	1201个化合物预溶于10mM DMSO，13个化合物预溶于10mM水，41个化合物预溶于2mM DMSO
容器:	带有螺旋盖和二维码的96孔储存管
储存条件:	1年 -20°C溶于DMSO
储存条件:	2年 -80°C溶于DMSO
发货:	干冰或蓝冰物流
包装:	惰性气体

Kinase Inhibitor Library组成

HTS Facility Partners

查看其他分子库

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2684种获得上市批准的原料药的独特集合，可用于高通量筛选和高内涵筛选。
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Express-Pick Library

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Anti-Aging Compound Library

1504种抗衰老化合物的集合，可用于衰老相关研究。
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Antibiotics compound Library

308种抗生素的独特集合，可用于鉴定药物靶标并探索治疗人类疾病的新机制和方法。
Anti-cancer Compound Library

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Anti-diabetic Compound Library

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Anti-infection Compound Library

930种抗感染化合物的独特集合，具有抗细菌，抗真菌，抗病毒等生物活性。
Antioxidant Compound Library

429种化合物的独特集合，用于探索抗氧化与衰老，癌症，阿尔茨海默病，帕金森病，糖尿病等疾病之间的关系。
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349种抗病毒化合物的独特集合，用于探索新型抗病毒药物。
Apoptosis Compound Library

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120种小分子化合物的独特集合，用于研究细胞周期和相关疾病。
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307个独特的血脑屏障通透化合物集合，具有生物活性，可用于神经系统研究。
Covalent Inhibitor Library

81种共价抑制剂的独特集合，用于高通量筛选（HTS）和高含量筛选（HCS）。
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185种化合物的独特集合，用于研究细胞骨架以及细胞骨架间的相互作用。
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用于DNA损伤和修复研究的179种小分子的独特集合，靶向PARP，ATM / ATR，拓扑异构酶，DNA / RNA合成等。
Epigenetics Compound Library

具有生物活性的467种化合物的独特集合，用于表观遗传学研究和相关分析
Ferroptosis Compound Library

76种化合物的独特集合，用于探索一种铁依赖性的非凋亡性细胞死亡即铁死亡的机制
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112种具有生物活性的小分子的独特集合，用于组蛋白修饰研究和相关分析。
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提供232种离子通道配体化合物集合，可用于多种类型离子通道实验研究。
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50个小分子的独特集合，用于研究JAK-STAT信号通路
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提供94种MAPK抑制剂药物集合，可用于MAPK信号通路实验研究。
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研究领域

产品类型