Shikonin

别名: C.I. 75535, Anchusin, Anchusa acid, Alkanna Red, Isoarnebin 4, NSC 252844 中文名称:紫草素

Shikonin是一种 Pyruvate kinase M2 (PKM2) 有效的、特异的抑制剂。它是紫草的主要成分,紫草是一种中草药,具有多种生物活性。在细胞荧光淬灭试验中,Shikonin也是TMEM16A氯离子通道的抑制剂。Shikonin 通过抑制 tumor necrosis factor-α (TNF-α) 发挥抗炎作用,并可通过抑制 proteasome 来阻止 nuclear factor-κB (NF-κB) 信号途径的激活。

Shikonin Chemical Structure

Shikonin Chemical Structure

CAS: 54952-43-1

规格 价格 库存 购买数量
10mM (1mL in DMSO) RMB 810.81 现货
20mg RMB 794.69 现货
100mg RMB 2433.41 现货
更大包装 有超大折扣

400-668-6834

info@selleck.cn

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客户使用Selleck的Shikonin发表文献32

产品质控

批次: 纯度: 99.03%
98.33

Shikonin相关产品

PKM抑制剂选择性比较

细胞实验数据示例

细胞系 实验类型 给药浓度 孵育时间 活性描述 文献信息
HCT116 Cytotoxicity assay 24 hrs Cytotoxicity against MDR1 Pgp under-expressing human HCT116 cells after 24 hrs by MTT assay, IC50=0.23μM. 17949858
HepG2 Cytotoxicity assay 24 hrs Cytotoxicity against MDR1 Pgp overexpressing human HepG2 cells after 24 hrs by MTT assay, IC50=0.24μM. 17949858
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50=0.63μM. 20403646
K562/ADR Cytotoxicity assay 72 hrs Cytotoxicity against human K562/ADR cells after 72 hrs by MTT assay, IC50=0.67μM. 20403646
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50=1.03μM. 20403646
HL60/ADR Cytotoxicity assay 72 hrs Cytotoxicity against human HL60/ADR cells after 72 hrs by MTT assay, IC50=1.41μM. 20403646
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50=1.45μM. 20403646
K562 Cytotoxicity assay 24 hrs Cytotoxicity against human K562 cells after 24 hrs by MTT assay, IC50=0.6μM. 20970893
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50=1.9μM. 20970893
HT-29 Cytotoxicity assay 24 hrs Cytotoxicity against human HT-29 cells after 24 hrs by MTT assay, IC50=15.8μM. 20970893
CNE Antitumor assay 24 hrs Antitumor activity against human CNE cells after 24 hrs by MTT assay, IC50=0.7μM. 21620530
L929 Cytotoxicity assay 24 hrs Cytotoxicity against mouse L929 cells after 24 hrs by MTT assay, IC50=3.2μM. 21620530
MDA-MB-231 Antitumor assay 24 hrs Antitumor activity against human MDA-MB-231 cells after 24 hrs by MTT assay, IC50=6.6μM. 21620530
HCT15 Antitumor assay 24 hrs Antitumor activity against human HCT15 cells after 24 hrs by MTT assay, IC50=7.3μM. 21620530
MIAPaCa2 Cytotoxicity assay 72 hrs Cytotoxicity against human MIAPaCa2 cells assessed as reduction in cell growth after 72 hrs by cell titer glo assay, IC50=0.04μM. 27080175
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell growth after 72 hrs by cell titer glo assay, IC50=3.94μM. 27080175
MCF10 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF10 cells assessed as reduction in cell growth after 72 hrs by cell titer glo assay, IC50=4.56μM. 27080175
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by cell titer glo assay, IC50=5.49μM. 27080175
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by cell titer glo assay, IC50=6.42μM. 27080175
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTS assay, IC50=1.84μM. 28688274
NCI-H1299 Antiproliferative assay 48 hrs Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay, IC50=1.88μM. 28688274
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay, IC50=2.45μM. 28688274
BEAS2B Cytotoxicity assay 48 hrs Cytotoxicity against human BEAS2B cells assessed as reduction in cell viability after 48 hrs by MTS assay, IC50=5.36μM. 28688274
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay, IC50=0.86μM. 29174813
Bel7402 Cytotoxicity assay 48 hrs Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay, IC50=1.24μM. 29174813
HSF Cytotoxicity assay 48 hrs Cytotoxicity against human HSF cells after 48 hrs by MTT assay, IC50=1.25μM. 29174813
MGC803 Cytotoxicity assay 48 hrs Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay, IC50=1.51μM. 29174813
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50=2.4μM. 29174813
LO2 Antiproliferative assay 24 hrs Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay, IC50=3.41μM. 29268130
A549 Antiproliferative assay 24 hrs Antiproliferative activity against human A549 cells after 24 hrs by MTT assay, IC50=3.53μM. 29268130
HeLa Antiproliferative assay 24 hrs Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay, IC50=6.86μM. 29268130
HepG2 Antiproliferative assay 24 hrs Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay, IC50=6.92μM. 29268130
MDA231 Antiproliferative assay 24 hrs Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay, IC50=8.75μM. 29268130
HCT15 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50=0.86μM. 30677614
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50=1.02μM. 30677614
HSF Cytotoxicity assay 72 hrs Cytotoxicity against human HSF cells after 72 hrs by MTT assay, IC50=1.25μM. 30677614
MGC803 Cytotoxicity assay 72 hrs Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay, IC50=1.51μM. 30677614
MCF7 Function assay 72 hrs Inhibition of topoisomerase 2 in human MCF7 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=5.7μM. 30846253
HepG2 Function assay 72 hrs Inhibition of topoisomerase 2 in human HepG2 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=6.2μM. 30846253
HeLa Function assay 72 hrs Inhibition of topoisomerase 2 in human HeLa cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=6.7μM. 30846253
MDA-MB-231 Function assay 72 hrs Inhibition of topoisomerase 2 in human MDA-MB-231 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=7.8μM. 30846253
CNE1 Function assay 72 hrs Inhibition of topoisomerase 2 in human CNE1 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=12.5μM. 30846253
L02 Cytotoxicity assay 72 hrs Cytotoxicity against human L02 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay, IC50=13μM. 30846253
A549 Function assay 72 hrs Inhibition of topoisomerase 2 in human A549 cells assessed as reduction in cell growth measured after 72 hrs by MTT assay, IC50=16μM. 30846253
HEK293T Cytotoxicity assay 24 hrs Cytotoxicity against HEK293T cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=1.52μM. 31404864
L02 Cytotoxicity assay 24 hrs Cytotoxicity against human L02 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.22μM. 31404864
MDA-MB-231 Cytotoxicity assay 24 hrs Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.5μM. 31404864
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.5μM. 31404864
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.5μM. 31404864
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.5μM. 31404864
THP1 Cytotoxicity assay 24 hrs Cytotoxicity against human THP1 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=0.82μM. 31563013
Jurkat Cytotoxicity assay 24 hrs Cytotoxicity against human Jurkat cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=0.97μM. 31563013
U937 Cytotoxicity assay 24 hrs Cytotoxicity against human U937 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=1.2μM. 31563013
HL60 Cytotoxicity assay 24 hrs Cytotoxicity against human HL60 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=1.2μM. 31563013
MONO-MAC-6 Cytotoxicity assay 24 hrs Cytotoxicity against human MONO-MAC-6 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=2.6μM. 31563013
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=2.7μM. 31563013
SW982 Cytotoxicity assay 24 hrs Cytotoxicity against human SW982 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=2.8μM. 31563013
PBMC Cytotoxicity assay 24 hrs Cytotoxicity against human PBMC cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=5μM. 31563013
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=7.3μM. 31563013
LS174T Cytotoxicity assay 24 hrs Cytotoxicity against human LS174T cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent cell viability assay, IC50=8.9μM. 31563013
Sf9 Function assay 30 mins Inhibition of C-terminal His-tagged N-terminal GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus infected Sf9 cells after 30 mins in presence of gamma-[32p-ATP] binding assay, IC50=0.1392μM. 31648877
NCI-H1975 Antiproliferative assay 24 hrs Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=4.28μM. 31648877
H460 Antiproliferative assay 24 hrs Antiproliferative activity against human H460 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=5.04μM. 31648877
A549 Antiproliferative assay 24 hrs Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=6.13μM. 31648877
HeLa Antiproliferative assay 24 hrs Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=7.84μM. 31648877
MCF7 Antiproliferative assay 24 hrs Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50=9.55μM. 31648877
LO2 Cytotoxicity assay 24 hrs Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 24 hrs by MTT assay, CC50=12.2μM. 31648877
Daoy Growth inhibition assay Inhibition of human Daoy cell growth in a cell viability assay, IC50=0.15877μM. SANGER
RPMI-7951 Growth inhibition assay Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50=0.15609μM. SANGER
IGR-1 Growth inhibition assay Inhibition of human IGR-1 cell growth in a cell viability assay, IC50=0.15398μM. SANGER
DEL Growth inhibition assay Inhibition of human DEL cell growth in a cell viability assay, IC50=0.15381μM. SANGER
MEL-HO Growth inhibition assay Inhibition of human MEL-HO cell growth in a cell viability assay, IC50=0.14882μM. SANGER
REH Growth inhibition assay Inhibition of human REH cell growth in a cell viability assay, IC50=0.14696μM. SANGER
ACHN Growth inhibition assay Inhibition of human ACHN cell growth in a cell viability assay, IC50=0.14638μM. SANGER
NTERA-S-cl-D1 Growth inhibition assay Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50=0.14357μM. SANGER
J82 Growth inhibition assay Inhibition of human J82 cell growth in a cell viability assay, IC50=0.14255μM. SANGER
SR Growth inhibition assay Inhibition of human SR cell growth in a cell viability assay, IC50=0.14073μM. SANGER
KYSE-450 Growth inhibition assay Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50=0.13815μM. SANGER
NCI-H2342 Growth inhibition assay Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50=0.13445μM. SANGER
M059J Growth inhibition assay Inhibition of human M059J cell growth in a cell viability assay, IC50=0.13419μM. SANGER
A204 Growth inhibition assay Inhibition of human A204 cell growth in a cell viability assay, IC50=0.12654μM. SANGER
KASUMI-1 Growth inhibition assay Inhibition of human KASUMI-1 cell growth in a cell viability assay, IC50=0.12371μM. SANGER
MZ7-mel Growth inhibition assay Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50=0.11372μM. SANGER
SK-LMS-1 Growth inhibition assay Inhibition of human SK-LMS-1 cell growth in a cell viability assay, IC50=0.10841μM. SANGER
A431 Growth inhibition assay Inhibition of human A431 cell growth in a cell viability assay, IC50=0.10697μM. SANGER
GR-ST Growth inhibition assay Inhibition of human GR-ST cell growth in a cell viability assay, IC50=0.10218μM. SANGER
MRK-nu-1 Growth inhibition assay Inhibition of human MRK-nu-1 cell growth in a cell viability assay, IC50=0.10193μM. SANGER
NKM-1 Growth inhibition assay Inhibition of human NKM-1 cell growth in a cell viability assay, IC50=0.1012μM. SANGER
NCI-H1963 Growth inhibition assay Inhibition of human NCI-H1963 cell growth in a cell viability assay, IC50=0.10011μM. SANGER
AM-38 Growth inhibition assay Inhibition of human AM-38 cell growth in a cell viability assay, IC50=0.09631μM. SANGER
HLE Growth inhibition assay Inhibition of human HLE cell growth in a cell viability assay, IC50=0.08831μM. SANGER
8-MG-BA Growth inhibition assay Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50=0.08556μM. SANGER
A498 Growth inhibition assay Inhibition of human A498 cell growth in a cell viability assay, IC50=0.0819μM. SANGER
AN3-CA Growth inhibition assay Inhibition of human AN3-CA cell growth in a cell viability assay, IC50=0.07965μM. SANGER
RT-112 Growth inhibition assay Inhibition of human RT-112 cell growth in a cell viability assay, IC50=0.07037μM. SANGER
NCI-H2052 Growth inhibition assay Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50=0.06113μM. SANGER
SW982 Growth inhibition assay Inhibition of human SW982 cell growth in a cell viability assay, IC50=0.06023μM. SANGER
HMV-II Growth inhibition assay Inhibition of human HMV-II cell growth in a cell viability assay, IC50=0.0564μM. SANGER
IGROV-1 Growth inhibition assay Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50=0.05561μM. SANGER
KS-1 Growth inhibition assay Inhibition of human KS-1 cell growth in a cell viability assay, IC50=0.0415μM. SANGER
MES-SA Growth inhibition assay Inhibition of human MES-SA cell growth in a cell viability assay, IC50=0.04132μM. SANGER
SK-PN-DW Growth inhibition assay Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50=0.03655μM. SANGER
GCIY Growth inhibition assay Inhibition of human GCIY cell growth in a cell viability assay, IC50=0.03598μM. SANGER
CAL-51 Growth inhibition assay Inhibition of human CAL-51 cell growth in a cell viability assay, IC50=0.02085μM. SANGER
NCI-H2009 Growth inhibition assay Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50=0.02054μM. SANGER
MZ1-PC Growth inhibition assay Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50=0.01928μM. SANGER
A427 Growth inhibition assay Inhibition of human A427 cell growth in a cell viability assay, IC50=0.01799μM. SANGER
KU812 Growth inhibition assay Inhibition of human KU812 cell growth in a cell viability assay, IC50=0.008306μM. SANGER
A253 Growth inhibition assay Inhibition of human A253 cell growth in a cell viability assay, IC50=0.007493μM. SANGER
SK-UT-1 Growth inhibition assay Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50=0.007438μM. SANGER
ST486 Growth inhibition assay Inhibition of human ST486 cell growth in a cell viability assay, IC50=0.006179μM. SANGER
SW1710 Growth inhibition assay Inhibition of human SW1710 cell growth in a cell viability assay, IC50=0.00291μM. SANGER
NALM-6 Growth inhibition assay Inhibition of human NALM-6 cell growth in a cell viability assay, IC50=0.002797μM. SANGER
TE-441-T Growth inhibition assay Inhibition of human TE-441-T cell growth in a cell viability assay, IC50=0.002238μM. SANGER
A101D Growth inhibition assay Inhibition of human A101D cell growth in a cell viability assay, IC50=0.0007121μM. SANGER
CAL-85-1 Growth inhibition assay Inhibition of human CAL-85-1 cell growth in a cell viability assay, IC50=0.16073μM. SANGER
SNU-423 Growth inhibition assay Inhibition of human SNU-423 cell growth in a cell viability assay, IC50=0.16307μM. SANGER
PANC-03-27 Growth inhibition assay Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50=0.1674μM. SANGER
CHL-1 Growth inhibition assay Inhibition of human CHL-1 cell growth in a cell viability assay, IC50=0.1678μM. SANGER
SIG-M5 Growth inhibition assay Inhibition of human SIG-M5 cell growth in a cell viability assay, IC50=0.16986μM. SANGER
DU-4475 Growth inhibition assay Inhibition of human DU-4475 cell growth in a cell viability assay, IC50=0.17984μM. SANGER
QIMR-WIL Growth inhibition assay Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50=0.18189μM. SANGER
COLO-679 Growth inhibition assay Inhibition of human COLO-679 cell growth in a cell viability assay, IC50=0.18401μM. SANGER
HOS Growth inhibition assay Inhibition of human HOS cell growth in a cell viability assay, IC50=0.18608μM. SANGER
CA46 Growth inhibition assay Inhibition of human CA46 cell growth in a cell viability assay, IC50=0.19185μM. SANGER
DU-145 Growth inhibition assay Inhibition of human DU-145 cell growth in a cell viability assay, IC50=0.19309μM. SANGER
HAL-01 Growth inhibition assay Inhibition of human HAL-01 cell growth in a cell viability assay, IC50=0.19573μM. SANGER
SCC-9 Growth inhibition assay Inhibition of human SCC-9 cell growth in a cell viability assay, IC50=0.19675μM. SANGER
IST-SL2 Growth inhibition assay Inhibition of human IST-SL2 cell growth in a cell viability assay, IC50=0.20014μM. SANGER
PA-1 Growth inhibition assay Inhibition of human PA-1 cell growth in a cell viability assay, IC50=0.20128μM. SANGER
BT-474 Growth inhibition assay Inhibition of human BT-474 cell growth in a cell viability assay, IC50=0.20836μM. SANGER
EFM-19 Growth inhibition assay Inhibition of human EFM-19 cell growth in a cell viability assay, IC50=0.2121μM. SANGER
NB69 Growth inhibition assay Inhibition of human NB69 cell growth in a cell viability assay, IC50=0.21273μM. SANGER
SBC-5 Growth inhibition assay Inhibition of human SBC-5 cell growth in a cell viability assay, IC50=0.21546μM. SANGER
KYSE-270 Growth inhibition assay Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50=0.21692μM. SANGER
P30-OHK Growth inhibition assay Inhibition of human P30-OHK cell growth in a cell viability assay, IC50=0.22048μM. SANGER
T47D Growth inhibition assay Inhibition of human T47D cell growth in a cell viability assay, IC50=0.22306μM. SANGER
HSC-2 Growth inhibition assay Inhibition of human HSC-2 cell growth in a cell viability assay, IC50=0.22318μM. SANGER
HGC-27 Growth inhibition assay Inhibition of human HGC-27 cell growth in a cell viability assay, IC50=0.22834μM. SANGER
YKG-1 Growth inhibition assay Inhibition of human YKG-1 cell growth in a cell viability assay, IC50=0.22891μM. SANGER
COR-L105 Growth inhibition assay Inhibition of human COR-L105 cell growth in a cell viability assay, IC50=0.23034μM. SANGER
LB647-SCLC Growth inhibition assay Inhibition of human LB647-SCLC cell growth in a cell viability assay, IC50=0.23278μM. SANGER
G-401 Growth inhibition assay Inhibition of human G-401 cell growth in a cell viability assay, IC50=0.23492μM. SANGER
MKN1 Growth inhibition assay Inhibition of human MKN1 cell growth in a cell viability assay, IC50=0.23576μM. SANGER
NCI-H1770 Growth inhibition assay Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50=0.24314μM. SANGER
BB30-HNC Growth inhibition assay Inhibition of human BB30-HNC cell growth in a cell viability assay, IC50=0.24349μM. SANGER
KE-37 Growth inhibition assay Inhibition of human KE-37 cell growth in a cell viability assay, IC50=0.24445μM. SANGER
MONO-MAC-6 Growth inhibition assay Inhibition of human MONO-MAC-6 cell growth in a cell viability assay, IC50=0.24477μM. SANGER
A4-Fuk Growth inhibition assay Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50=0.24973μM. SANGER
MHH-PREB-1 Growth inhibition assay Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50=0.25157μM. SANGER
KYSE-510 Growth inhibition assay Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50=0.2527μM. SANGER
MG-63 Growth inhibition assay Inhibition of human MG-63 cell growth in a cell viability assay, IC50=0.25677μM. SANGER
HT-1080 Growth inhibition assay Inhibition of human HT-1080 cell growth in a cell viability assay, IC50=0.25995μM. SANGER
WSU-NHL Growth inhibition assay Inhibition of human WSU-NHL cell growth in a cell viability assay, IC50=0.26033μM. SANGER
DoTc2-4510 Growth inhibition assay Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50=0.26279μM. SANGER
639-V Growth inhibition assay Inhibition of human 639-V cell growth in a cell viability assay, IC50=0.26501μM. SANGER
EW-13 Growth inhibition assay Inhibition of human EW-13 cell growth in a cell viability assay, IC50=0.26674μM. SANGER
HCT-15 Growth inhibition assay Inhibition of human HCT-15 cell growth in a cell viability assay, IC50=0.26758μM. SANGER
RKO Growth inhibition assay Inhibition of human RKO cell growth in a cell viability assay, IC50=0.2703μM. SANGER
SNG-M Growth inhibition assay Inhibition of human SNG-M cell growth in a cell viability assay, IC50=0.27237μM. SANGER
MV-4-11 Growth inhibition assay Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50=0.27363μM. SANGER
HT-1197 Growth inhibition assay Inhibition of human HT-1197 cell growth in a cell viability assay, IC50=0.27582μM. SANGER
MIA-PaCa-2 Growth inhibition assay Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50=0.27649μM. SANGER
BL-70 Growth inhibition assay Inhibition of human BL-70 cell growth in a cell viability assay, IC50=0.27802μM. SANGER
ME-180 Growth inhibition assay Inhibition of human ME-180 cell growth in a cell viability assay, IC50=0.27891μM. SANGER
BFTC-905 Growth inhibition assay Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50=0.28361μM. SANGER
H4 Growth inhibition assay Inhibition of human H4 cell growth in a cell viability assay, IC50=0.28393μM. SANGER
no-10 Growth inhibition assay Inhibition of human no-10 cell growth in a cell viability assay, IC50=0.29023μM. SANGER
OCI-AML2 Growth inhibition assay Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50=0.29837μM. SANGER
EW-16 Growth inhibition assay Inhibition of human EW-16 cell growth in a cell viability assay, IC50=0.29915μM. SANGER
U-698-M Growth inhibition assay Inhibition of human U-698-M cell growth in a cell viability assay, IC50=0.30087μM. SANGER
COR-L23 Growth inhibition assay Inhibition of human COR-L23 cell growth in a cell viability assay, IC50=0.3015μM. SANGER
LB1047-RCC Growth inhibition assay Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50=0.30244μM. SANGER
8305C Growth inhibition assay Inhibition of human 8305C cell growth in a cell viability assay, IC50=0.30484μM. SANGER
EB2 Growth inhibition assay Inhibition of human EB2 cell growth in a cell viability assay, IC50=0.31095μM. SANGER
A375 Growth inhibition assay Inhibition of human A375 cell growth in a cell viability assay, IC50=0.31111μM. SANGER
OS-RC-2 Growth inhibition assay Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50=0.31389μM. SANGER
Ramos-2G6-4C10 Growth inhibition assay Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50=0.31503μM. SANGER
ALL-PO Growth inhibition assay Inhibition of human ALL-PO cell growth in a cell viability assay, IC50=0.31512μM. SANGER
NB13 Growth inhibition assay Inhibition of human NB13 cell growth in a cell viability assay, IC50=0.31693μM. SANGER
EFO-27 Growth inhibition assay Inhibition of human EFO-27 cell growth in a cell viability assay, IC50=0.33034μM. SANGER
BxPC-3 Growth inhibition assay Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50=0.33358μM. SANGER
HSC-3 Growth inhibition assay Inhibition of human HSC-3 cell growth in a cell viability assay, IC50=0.33666μM. SANGER
HCC2157 Growth inhibition assay Inhibition of human HCC2157 cell growth in a cell viability assay, IC50=0.33783μM. SANGER
OPM-2 Growth inhibition assay Inhibition of human OPM-2 cell growth in a cell viability assay, IC50=0.34326μM. SANGER
786-0 Growth inhibition assay Inhibition of human 786-0 cell growth in a cell viability assay, IC50=0.34375μM. SANGER
GT3TKB Growth inhibition assay Inhibition of human GT3TKB cell growth in a cell viability assay, IC50=0.3455μM. SANGER
LCLC-103H Growth inhibition assay Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50=0.3456μM. SANGER
MN-60 Growth inhibition assay Inhibition of human MN-60 cell growth in a cell viability assay, IC50=0.34788μM. SANGER
KP-N-YS Growth inhibition assay Inhibition of human KP-N-YS cell growth in a cell viability assay, IC50=0.3517μM. SANGER
CMK Growth inhibition assay Inhibition of human CMK cell growth in a cell viability assay, IC50=0.35213μM. SANGER
ONS-76 Growth inhibition assay Inhibition of human ONS-76 cell growth in a cell viability assay, IC50=0.35807μM. SANGER
647-V Growth inhibition assay Inhibition of human 647-V cell growth in a cell viability assay, IC50=0.35852μM. SANGER
SW620 Growth inhibition assay Inhibition of human SW620 cell growth in a cell viability assay, IC50=0.35855μM. SANGER
LC4-1 Growth inhibition assay Inhibition of human LC4-1 cell growth in a cell viability assay, IC50=0.36029μM. SANGER
SW872 Growth inhibition assay Inhibition of human SW872 cell growth in a cell viability assay, IC50=0.36748μM. SANGER
SJRH30 Growth inhibition assay Inhibition of human SJRH30 cell growth in a cell viability assay, IC50=0.3692μM. SANGER
HUTU-80 Growth inhibition assay Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50=0.3702μM. SANGER
SH-4 Growth inhibition assay Inhibition of human SH-4 cell growth in a cell viability assay, IC50=0.37135μM. SANGER
SW1573 Growth inhibition assay Inhibition of human SW1573 cell growth in a cell viability assay, IC50=0.3718μM. SANGER
KYSE-140 Growth inhibition assay Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50=0.37393μM. SANGER
RPMI-2650 Growth inhibition assay Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50=0.37474μM. SANGER
SCC-25 Growth inhibition assay Inhibition of human SCC-25 cell growth in a cell viability assay, IC50=0.38264μM. SANGER
OVCAR-3 Growth inhibition assay Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50=0.38281μM. SANGER
YT Growth inhibition assay Inhibition of human YT cell growth in a cell viability assay, IC50=0.38389μM. SANGER
COLO-320-HSR Growth inhibition assay Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50=0.38448μM. SANGER
MZ2-MEL Growth inhibition assay Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50=0.38522μM. SANGER
HCT-116 Growth inhibition assay Inhibition of human HCT-116 cell growth in a cell viability assay, IC50=0.38626μM. SANGER
S-117 Growth inhibition assay Inhibition of human S-117 cell growth in a cell viability assay, IC50=0.3871μM. SANGER
MC-IXC Growth inhibition assay Inhibition of human MC-IXC cell growth in a cell viability assay, IC50=0.38738μM. SANGER
HCC1599 Growth inhibition assay Inhibition of human HCC1599 cell growth in a cell viability assay, IC50=0.38827μM. SANGER
HCE-4 Growth inhibition assay Inhibition of human HCE-4 cell growth in a cell viability assay, IC50=0.38884μM. SANGER
LB373-MEL-D Growth inhibition assay Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50=0.39074μM. SANGER
DMS-273 Growth inhibition assay Inhibition of human DMS-273 cell growth in a cell viability assay, IC50=0.39579μM. SANGER
TE-15 Growth inhibition assay Inhibition of human TE-15 cell growth in a cell viability assay, IC50=0.40031μM. SANGER
COLO-684 Growth inhibition assay Inhibition of human COLO-684 cell growth in a cell viability assay, IC50=0.40053μM. SANGER
VA-ES-BJ Growth inhibition assay Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50=0.40058μM. SANGER
SW780 Growth inhibition assay Inhibition of human SW780 cell growth in a cell viability assay, IC50=0.40552μM. SANGER
C8166 Growth inhibition assay Inhibition of human C8166 cell growth in a cell viability assay, IC50=0.40751μM. SANGER
TE-9 Growth inhibition assay Inhibition of human TE-9 cell growth in a cell viability assay, IC50=0.40752μM. SANGER
EVSA-T Growth inhibition assay Inhibition of human EVSA-T cell growth in a cell viability assay, IC50=0.4098μM. SANGER
MOLT-4 Growth inhibition assay Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50=0.41012μM. SANGER
LOXIMVI Growth inhibition assay Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50=0.41185μM. SANGER
PANC-10-05 Growth inhibition assay Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50=0.41563μM. SANGER
RS4-11 Growth inhibition assay Inhibition of human RS4-11 cell growth in a cell viability assay, IC50=0.41676μM. SANGER
MCF7 Growth inhibition assay Inhibition of human MCF7 cell growth in a cell viability assay, IC50=0.43485μM. SANGER
BV-173 Growth inhibition assay Inhibition of human BV-173 cell growth in a cell viability assay, IC50=0.43595μM. SANGER
SCC-4 Growth inhibition assay Inhibition of human SCC-4 cell growth in a cell viability assay, IC50=0.4406μM. SANGER
NCI-H2087 Growth inhibition assay Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50=0.44072μM. SANGER
NCI-H747 Growth inhibition assay Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50=0.44139μM. SANGER
SHP-77 Growth inhibition assay Inhibition of human SHP-77 cell growth in a cell viability assay, IC50=0.44554μM. SANGER
EW-11 Growth inhibition assay Inhibition of human EW-11 cell growth in a cell viability assay, IC50=0.44716μM. SANGER
RD Growth inhibition assay Inhibition of human RD cell growth in a cell viability assay, IC50=0.44906μM. SANGER
MEG-01 Growth inhibition assay Inhibition of human MEG-01 cell growth in a cell viability assay, IC50=0.45125μM. SANGER
NB6 Growth inhibition assay Inhibition of human NB6 cell growth in a cell viability assay, IC50=0.4544μM. SANGER
OVCAR-8 Growth inhibition assay Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50=0.46005μM. SANGER
CAS-1 Growth inhibition assay Inhibition of human CAS-1 cell growth in a cell viability assay, IC50=0.46211μM. SANGER
HO-1-N-1 Growth inhibition assay Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50=0.46212μM. SANGER
TUR Growth inhibition assay Inhibition of human TUR cell growth in a cell viability assay, IC50=0.46599μM. SANGER
SW954 Growth inhibition assay Inhibition of human SW954 cell growth in a cell viability assay, IC50=0.46671μM. SANGER
A172 Growth inhibition assay Inhibition of human A172 cell growth in a cell viability assay, IC50=0.46975μM. SANGER
HD-MY-Z Growth inhibition assay Inhibition of human HD-MY-Z cell growth in a cell viability assay, IC50=0.47014μM. SANGER
RPMI-8226 Growth inhibition assay Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50=0.47188μM. SANGER
G-361 Growth inhibition assay Inhibition of human G-361 cell growth in a cell viability assay, IC50=0.47321μM. SANGER
HuCCT1 Growth inhibition assay Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50=0.48302μM. SANGER
CAL-39 Growth inhibition assay Inhibition of human CAL-39 cell growth in a cell viability assay, IC50=0.48323μM. SANGER
BL-41 Growth inhibition assay Inhibition of human BL-41 cell growth in a cell viability assay, IC50=0.4834μM. SANGER
MHH-NB-11 Growth inhibition assay Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50=0.48595μM. SANGER
HCC2218 Growth inhibition assay Inhibition of human HCC2218 cell growth in a cell viability assay, IC50=0.49603μM. SANGER
SK-MM-2 Growth inhibition assay Inhibition of human SK-MM-2 cell growth in a cell viability assay, IC50=0.49897μM. SANGER
SU-DHL-1 Growth inhibition assay Inhibition of human SU-DHL-1 cell growth in a cell viability assay, IC50=0.49922μM. SANGER
CGTH-W-1 Growth inhibition assay Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50=0.49993μM. SANGER
KP-4 Growth inhibition assay Inhibition of human KP-4 cell growth in a cell viability assay, IC50=0.5008μM. SANGER
NCI-H810 Growth inhibition assay Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50=0.50262μM. SANGER
ES1 Growth inhibition assay Inhibition of human ES1 cell growth in a cell viability assay, IC50=0.50289μM. SANGER
EoL-1-cell Growth inhibition assay Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50=0.50875μM. SANGER
NCCIT Growth inhibition assay Inhibition of human NCCIT cell growth in a cell viability assay, IC50=0.51716μM. SANGER
Mewo Growth inhibition assay Inhibition of human Mewo cell growth in a cell viability assay, IC50=0.51732μM. SANGER
NCI-H1522 Growth inhibition assay Inhibition of human NCI-H1522 cell growth in a cell viability assay, IC50=0.51944μM. SANGER
TGW Growth inhibition assay Inhibition of human TGW cell growth in a cell viability assay, IC50=0.52164μM. SANGER
EW-18 Growth inhibition assay Inhibition of human EW-18 cell growth in a cell viability assay, IC50=0.52862μM. SANGER
HCC1143 Growth inhibition assay Inhibition of human HCC1143 cell growth in a cell viability assay, IC50=0.52969μM. SANGER
RPMI-8866 Growth inhibition assay Inhibition of human RPMI-8866 cell growth in a cell viability assay, IC50=0.53604μM. SANGER
LS-123 Growth inhibition assay Inhibition of human LS-123 cell growth in a cell viability assay, IC50=0.53766μM. SANGER
COLO-205 Growth inhibition assay Inhibition of human COLO-205 cell growth in a cell viability assay, IC50=0.53772μM. SANGER
MLMA Growth inhibition assay Inhibition of human MLMA cell growth in a cell viability assay, IC50=0.53908μM. SANGER
MEL-JUSO Growth inhibition assay Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50=0.54014μM. SANGER
HTC-C3 Growth inhibition assay Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50=0.54237μM. SANGER
EFE-184 Growth inhibition assay Inhibition of human EFE-184 cell growth in a cell viability assay, IC50=0.54394μM. SANGER
VMRC-RCZ Growth inhibition assay Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50=0.54667μM. SANGER
NCI-H64 Growth inhibition assay Inhibition of human NCI-H64 cell growth in a cell viability assay, IC50=0.5471μM. SANGER
SK-HEP-1 Growth inhibition assay Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50=0.54751μM. SANGER
ES7 Growth inhibition assay Inhibition of human ES7 cell growth in a cell viability assay, IC50=0.54849μM. SANGER
GI-ME-N Growth inhibition assay Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50=0.55175μM. SANGER
TCCSUP Growth inhibition assay Inhibition of human TCCSUP cell growth in a cell viability assay, IC50=0.55445μM. SANGER
KMS-12-PE Growth inhibition assay Inhibition of human KMS-12-PE cell growth in a cell viability assay, IC50=0.55938μM. SANGER
NCI-H522 Growth inhibition assay Inhibition of human NCI-H522 cell growth in a cell viability assay, IC50=0.55979μM. SANGER
HT-144 Growth inhibition assay Inhibition of human HT-144 cell growth in a cell viability assay, IC50=0.56117μM. SANGER
NCI-H2030 Growth inhibition assay Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50=0.56265μM. SANGER
BHY Growth inhibition assay Inhibition of human BHY cell growth in a cell viability assay, IC50=0.56396μM. SANGER
CCRF-CEM Growth inhibition assay Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50=0.56702μM. SANGER
GI-1 Growth inhibition assay Inhibition of human GI-1 cell growth in a cell viability assay, IC50=0.56829μM. SANGER
SW962 Growth inhibition assay Inhibition of human SW962 cell growth in a cell viability assay, IC50=0.5683μM. SANGER
NCI-H1882 Growth inhibition assay Inhibition of human NCI-H1882 cell growth in a cell viability assay, IC50=0.57609μM. SANGER
OAW-42 Growth inhibition assay Inhibition of human OAW-42 cell growth in a cell viability assay, IC50=0.57768μM. SANGER
Ca9-22 Growth inhibition assay Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50=0.58063μM. SANGER
D-542MG Growth inhibition assay Inhibition of human D-542MG cell growth in a cell viability assay, IC50=0.58088μM. SANGER
LOUCY Growth inhibition assay Inhibition of human LOUCY cell growth in a cell viability assay, IC50=0.58606μM. SANGER
RPMI-6666 Growth inhibition assay Inhibition of human RPMI-6666 cell growth in a cell viability assay, IC50=0.58713μM. SANGER
C-4-II Growth inhibition assay Inhibition of human C-4-II cell growth in a cell viability assay, IC50=0.58772μM. SANGER
IMR-5 Growth inhibition assay Inhibition of human IMR-5 cell growth in a cell viability assay, IC50=0.5894μM. SANGER
COLO-680N Growth inhibition assay Inhibition of human COLO-680N cell growth in a cell viability assay, IC50=0.59003μM. SANGER
KYSE-520 Growth inhibition assay Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50=0.59842μM. SANGER
NCI-H1436 Growth inhibition assay Inhibition of human NCI-H1436 cell growth in a cell viability assay, IC50=0.60396μM. SANGER
MKN45 Growth inhibition assay Inhibition of human MKN45 cell growth in a cell viability assay, IC50=0.60839μM. SANGER
DBTRG-05MG Growth inhibition assay Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50=0.6111μM. SANGER
AGS Growth inhibition assay Inhibition of human AGS cell growth in a cell viability assay, IC50=0.61257μM. SANGER
LCLC-97TM1 Growth inhibition assay Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50=0.61312μM. SANGER
MKN28 Growth inhibition assay Inhibition of human MKN28 cell growth in a cell viability assay, IC50=0.61687μM. SANGER
ML-2 Growth inhibition assay Inhibition of human ML-2 cell growth in a cell viability assay, IC50=0.61774μM. SANGER
AsPC-1 Growth inhibition assay Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50=0.61887μM. SANGER
NCI-H1563 Growth inhibition assay Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50=0.62638μM. SANGER
Raji Growth inhibition assay Inhibition of human Raji cell growth in a cell viability assay, IC50=0.63117μM. SANGER
LU-165 Growth inhibition assay Inhibition of human LU-165 cell growth in a cell viability assay, IC50=0.63405μM. SANGER
SW626 Growth inhibition assay Inhibition of human SW626 cell growth in a cell viability assay, IC50=0.63513μM. SANGER
MDA-MB-157 Growth inhibition assay Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50=0.63663μM. SANGER
NCI-H727 Growth inhibition assay Inhibition of human NCI-H727 cell growth in a cell viability assay, IC50=0.6383μM. SANGER
HT-29 Growth inhibition assay Inhibition of human HT-29 cell growth in a cell viability assay, IC50=0.64457μM. SANGER
NCI-H226 Growth inhibition assay Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50=0.64517μM. SANGER
Ca-Ski Growth inhibition assay Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50=0.65031μM. SANGER
SCC-15 Growth inhibition assay Inhibition of human SCC-15 cell growth in a cell viability assay, IC50=0.6505μM. SANGER
NCI-H2196 Growth inhibition assay Inhibition of human NCI-H2196 cell growth in a cell viability assay, IC50=0.65427μM. SANGER
ES3 Growth inhibition assay Inhibition of human ES3 cell growth in a cell viability assay, IC50=0.65649μM. SANGER
ChaGo-K-1 Growth inhibition assay Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50=0.65672μM. SANGER
C3A Growth inhibition assay Inhibition of human C3A cell growth in a cell viability assay, IC50=0.65706μM. SANGER
NCI-H358 Growth inhibition assay Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50=0.65776μM. SANGER
COLO-829 Growth inhibition assay Inhibition of human COLO-829 cell growth in a cell viability assay, IC50=0.65799μM. SANGER
MFE-296 Growth inhibition assay Inhibition of human MFE-296 cell growth in a cell viability assay, IC50=0.66244μM. SANGER
SF295 Growth inhibition assay Inhibition of human SF295 cell growth in a cell viability assay, IC50=0.66418μM. SANGER
NCI-H650 Growth inhibition assay Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50=0.66519μM. SANGER
NB12 Growth inhibition assay Inhibition of human NB12 cell growth in a cell viability assay, IC50=0.66631μM. SANGER
OVCAR-4 Growth inhibition assay Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50=0.66955μM. SANGER
NCI-H2405 Growth inhibition assay Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50=0.67453μM. SANGER
U-266 Growth inhibition assay Inhibition of human U-266 cell growth in a cell viability assay, IC50=0.67516μM. SANGER
CAL-148 Growth inhibition assay Inhibition of human CAL-148 cell growth in a cell viability assay, IC50=0.6766μM. SANGER
KLE Growth inhibition assay Inhibition of human KLE cell growth in a cell viability assay, IC50=0.68466μM. SANGER
LP-1 Growth inhibition assay Inhibition of human LP-1 cell growth in a cell viability assay, IC50=0.68637μM. SANGER
MHH-ES-1 Growth inhibition assay Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50=0.68856μM. SANGER
769-P Growth inhibition assay Inhibition of human 769-P cell growth in a cell viability assay, IC50=0.6886μM. SANGER
SK-MEL-30 Growth inhibition assay Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50=0.6948μM. SANGER
CHP-126 Growth inhibition assay Inhibition of human CHP-126 cell growth in a cell viability assay, IC50=0.69535μM. SANGER
BB65-RCC Growth inhibition assay Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50=0.69545μM. SANGER
SW1088 Growth inhibition assay Inhibition of human SW1088 cell growth in a cell viability assay, IC50=0.69955μM. SANGER
DOHH-2 Growth inhibition assay Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50=0.70626μM. SANGER
ABC-1 Growth inhibition assay Inhibition of human ABC-1 cell growth in a cell viability assay, IC50=0.70748μM. SANGER
MDA-MB-134-VI Growth inhibition assay Inhibition of human MDA-MB-134-VI cell growth in a cell viability assay, IC50=0.7094μM. SANGER
MHH-CALL-2 Growth inhibition assay Inhibition of human MHH-CALL-2 cell growth in a cell viability assay, IC50=0.71504μM. SANGER
COLO-824 Growth inhibition assay Inhibition of human COLO-824 cell growth in a cell viability assay, IC50=0.7152μM. SANGER
RL95-2 Growth inhibition assay Inhibition of human RL95-2 cell growth in a cell viability assay, IC50=0.71973μM. SANGER
RH-1 Growth inhibition assay Inhibition of human RH-1 cell growth in a cell viability assay, IC50=0.71988μM. SANGER
HCE-T Growth inhibition assay Inhibition of human HCE-T cell growth in a cell viability assay, IC50=0.72009μM. SANGER
EW-3 Growth inhibition assay Inhibition of human EW-3 cell growth in a cell viability assay, IC50=0.7215μM. SANGER
DB Growth inhibition assay Inhibition of human DB cell growth in a cell viability assay, IC50=0.72629μM. SANGER
K5 Growth inhibition assay Inhibition of human K5 cell growth in a cell viability assay, IC50=0.73438μM. SANGER
KM12 Growth inhibition assay Inhibition of human KM12 cell growth in a cell viability assay, IC50=0.73971μM. SANGER
SNB75 Growth inhibition assay Inhibition of human SNB75 cell growth in a cell viability assay, IC50=0.74595μM. SANGER
KY821 Growth inhibition assay Inhibition of human KY821 cell growth in a cell viability assay, IC50=0.74685μM. SANGER
RXF393 Growth inhibition assay Inhibition of human RXF393 cell growth in a cell viability assay, IC50=0.74901μM. SANGER
SK-LU-1 Growth inhibition assay Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50=0.7501μM. SANGER
MMAC-SF Growth inhibition assay Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50=0.75196μM. SANGER
KYSE-410 Growth inhibition assay Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50=0.75242μM. SANGER
C2BBe1 Growth inhibition assay Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50=0.75564μM. SANGER
CAPAN-1 Growth inhibition assay Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50=0.75889μM. SANGER
SW756 Growth inhibition assay Inhibition of human SW756 cell growth in a cell viability assay, IC50=0.76177μM. SANGER
NUGC-3 Growth inhibition assay Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50=0.76543μM. SANGER
Caov-3 Growth inhibition assay Inhibition of human Caov-3 cell growth in a cell viability assay, IC50=0.7665μM. SANGER
CCF-STTG1 Growth inhibition assay Inhibition of human CCF-STTG1 cell growth in a cell viability assay, IC50=0.76801μM. SANGER
U031 Growth inhibition assay Inhibition of human U031 cell growth in a cell viability assay, IC50=0.77084μM. SANGER
SF126 Growth inhibition assay Inhibition of human SF126 cell growth in a cell viability assay, IC50=0.77297μM. SANGER
CESS Growth inhibition assay Inhibition of human CESS cell growth in a cell viability assay, IC50=0.77645μM. SANGER
SW684 Growth inhibition assay Inhibition of human SW684 cell growth in a cell viability assay, IC50=0.77733μM. SANGER
ES8 Growth inhibition assay Inhibition of human ES8 cell growth in a cell viability assay, IC50=0.77779μM. SANGER
HCC38 Growth inhibition assay Inhibition of human HCC38 cell growth in a cell viability assay, IC50=0.78651μM. SANGER
PF-382 Growth inhibition assay Inhibition of human PF-382 cell growth in a cell viability assay, IC50=0.78951μM. SANGER
KARPAS-299 Growth inhibition assay Inhibition of human KARPAS-299 cell growth in a cell viability assay, IC50=0.79941μM. SANGER
no-11 Growth inhibition assay Inhibition of human no-11 cell growth in a cell viability assay, IC50=0.80542μM. SANGER
OE19 Growth inhibition assay Inhibition of human OE19 cell growth in a cell viability assay, IC50=0.80734μM. SANGER
LU-134-A Growth inhibition assay Inhibition of human LU-134-A cell growth in a cell viability assay, IC50=0.80971μM. SANGER
HCC1569 Growth inhibition assay Inhibition of human HCC1569 cell growth in a cell viability assay, IC50=0.80994μM. SANGER
SNU-449 Growth inhibition assay Inhibition of human SNU-449 cell growth in a cell viability assay, IC50=0.81325μM. SANGER
MC-CAR Growth inhibition assay Inhibition of human MC-CAR cell growth in a cell viability assay, IC50=0.81362μM. SANGER
BEN Growth inhibition assay Inhibition of human BEN cell growth in a cell viability assay, IC50=0.81372μM. SANGER
NCI-H1417 Growth inhibition assay Inhibition of human NCI-H1417 cell growth in a cell viability assay, IC50=0.81592μM. SANGER
NCI-H596 Growth inhibition assay Inhibition of human NCI-H596 cell growth in a cell viability assay, IC50=0.81786μM. SANGER
SW1417 Growth inhibition assay Inhibition of human SW1417 cell growth in a cell viability assay, IC50=0.82583μM. SANGER
HuP-T3 Growth inhibition assay Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50=0.83373μM. SANGER
D-283MED Growth inhibition assay Inhibition of human D-283MED cell growth in a cell viability assay, IC50=0.83531μM. SANGER
NEC8 Growth inhibition assay Inhibition of human NEC8 cell growth in a cell viability assay, IC50=0.8399μM. SANGER
NCI-H1694 Growth inhibition assay Inhibition of human NCI-H1694 cell growth in a cell viability assay, IC50=0.84009μM. SANGER
U-118-MG Growth inhibition assay Inhibition of human U-118-MG cell growth in a cell viability assay, IC50=0.84185μM. SANGER
EW-1 Growth inhibition assay Inhibition of human EW-1 cell growth in a cell viability assay, IC50=0.8439μM. SANGER
ATN-1 Growth inhibition assay Inhibition of human ATN-1 cell growth in a cell viability assay, IC50=0.84913μM. SANGER
NH-12 Growth inhibition assay Inhibition of human NH-12 cell growth in a cell viability assay, IC50=0.85019μM. SANGER
NCI-H292 Growth inhibition assay Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50=0.85329μM. SANGER
SAS Growth inhibition assay Inhibition of human SAS cell growth in a cell viability assay, IC50=0.85374μM. SANGER
SF539 Growth inhibition assay Inhibition of human SF539 cell growth in a cell viability assay, IC50=0.85682μM. SANGER
MPP-89 Growth inhibition assay Inhibition of human MPP-89 cell growth in a cell viability assay, IC50=0.85725μM. SANGER
PC-3 Growth inhibition assay Inhibition of human PC-3 cell growth in a cell viability assay, IC50=0.85879μM. SANGER
CTB-1 Growth inhibition assay Inhibition of human CTB-1 cell growth in a cell viability assay, IC50=0.85902μM. SANGER
MFH-ino Growth inhibition assay Inhibition of human MFH-ino cell growth in a cell viability assay, IC50=0.86385μM. SANGER
RMG-I Growth inhibition assay Inhibition of human RMG-I cell growth in a cell viability assay, IC50=0.86423μM. SANGER
OCUB-M Growth inhibition assay Inhibition of human OCUB-M cell growth in a cell viability assay, IC50=0.86523μM. SANGER
A388 Growth inhibition assay Inhibition of human A388 cell growth in a cell viability assay, IC50=0.86656μM. SANGER
ARH-77 Growth inhibition assay Inhibition of human ARH-77 cell growth in a cell viability assay, IC50=0.87349μM. SANGER
697 Growth inhibition assay Inhibition of human 697 cell growth in a cell viability assay, IC50=0.87565μM. SANGER
G-402 Growth inhibition assay Inhibition of human G-402 cell growth in a cell viability assay, IC50=0.88167μM. SANGER
THP-1 Growth inhibition assay Inhibition of human THP-1 cell growth in a cell viability assay, IC50=0.89143μM. SANGER
CAKI-1 Growth inhibition assay Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50=0.89413μM. SANGER
MFM-223 Growth inhibition assay Inhibition of human MFM-223 cell growth in a cell viability assay, IC50=0.89877μM. SANGER
NCI-H2228 Growth inhibition assay Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50=0.90095μM. SANGER
HCC1954 Growth inhibition assay Inhibition of human HCC1954 cell growth in a cell viability assay, IC50=0.90182μM. SANGER
KYSE-150 Growth inhibition assay Inhibition of human KYSE-150 cell growth in a cell viability assay, IC50=0.90194μM. SANGER
NCI-H2171 Growth inhibition assay Inhibition of human NCI-H2171 cell growth in a cell viability assay, IC50=0.90896μM. SANGER
C-33-A Growth inhibition assay Inhibition of human C-33-A cell growth in a cell viability assay, IC50=0.91275μM. SANGER
D-392MG Growth inhibition assay Inhibition of human D-392MG cell growth in a cell viability assay, IC50=0.91529μM. SANGER
HT-1376 Growth inhibition assay Inhibition of human HT-1376 cell growth in a cell viability assay, IC50=0.91531μM. SANGER
ACN Growth inhibition assay Inhibition of human ACN cell growth in a cell viability assay, IC50=0.91695μM. SANGER
A2058 Growth inhibition assay Inhibition of human A2058 cell growth in a cell viability assay, IC50=0.91912μM. SANGER
BCPAP Growth inhibition assay Inhibition of human BCPAP cell growth in a cell viability assay, IC50=0.92259μM. SANGER
BC-3 Growth inhibition assay Inhibition of human BC-3 cell growth in a cell viability assay, IC50=0.92619μM. SANGER
HT-3 Growth inhibition assay Inhibition of human HT-3 cell growth in a cell viability assay, IC50=0.94827μM. SANGER
LC-2-ad Growth inhibition assay Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50=0.95255μM. SANGER
MDA-MB-468 Growth inhibition assay Inhibition of human MDA-MB-468 cell growth in a cell viability assay, IC50=0.96684μM. SANGER
UM-UC-3 Growth inhibition assay Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50=0.96727μM. SANGER
NCI-H2347 Growth inhibition assay Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50=0.96781μM. SANGER
EM-2 Growth inhibition assay Inhibition of human EM-2 cell growth in a cell viability assay, IC50=0.97693μM. SANGER
TE-10 Growth inhibition assay Inhibition of human TE-10 cell growth in a cell viability assay, IC50=0.98609μM. SANGER
NCI-H345 Growth inhibition assay Inhibition of human NCI-H345 cell growth in a cell viability assay, IC50=0.98957μM. SANGER
SCC-3 Growth inhibition assay Inhibition of human SCC-3 cell growth in a cell viability assay, IC50=1.00343μM. SANGER
TE-5 Growth inhibition assay Inhibition of human TE-5 cell growth in a cell viability assay, IC50=1.00432μM. SANGER
Capan-2 Growth inhibition assay Inhibition of human Capan-2 cell growth in a cell viability assay, IC50=1.00529μM. SANGER
NCI-H28 Growth inhibition assay Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50=1.00835μM. SANGER
KYSE-180 Growth inhibition assay Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50=1.01032μM. SANGER
CAL-72 Growth inhibition assay Inhibition of human CAL-72 cell growth in a cell viability assay, IC50=1.01293μM. SANGER
MDA-MB-231 Growth inhibition assay Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50=1.01544μM. SANGER
HCC1187 Growth inhibition assay Inhibition of human HCC1187 cell growth in a cell viability assay, IC50=1.01979μM. SANGER
VM-CUB-1 Growth inhibition assay Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50=1.02856μM. SANGER
NB1 Growth inhibition assay Inhibition of human NB1 cell growth in a cell viability assay, IC50=1.03434μM. SANGER
KM-H2 Growth inhibition assay Inhibition of human KM-H2 cell growth in a cell viability assay, IC50=1.03617μM. SANGER
GAK Growth inhibition assay Inhibition of human GAK cell growth in a cell viability assay, IC50=1.03769μM. SANGER
NY Growth inhibition assay Inhibition of human NY cell growth in a cell viability assay, IC50=1.04557μM. SANGER
SNU-387 Growth inhibition assay Inhibition of human SNU-387 cell growth in a cell viability assay, IC50=1.06857μM. SANGER
SW1783 Growth inhibition assay Inhibition of human SW1783 cell growth in a cell viability assay, IC50=1.06884μM. SANGER
NCI-H1299 Growth inhibition assay Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50=1.07194μM. SANGER
SK-NEP-1 Growth inhibition assay Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50=1.08112μM. SANGER
KNS-81-FD Growth inhibition assay Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50=1.08194μM. SANGER
T98G Growth inhibition assay Inhibition of human T98G cell growth in a cell viability assay, IC50=1.08208μM. SANGER
HT Growth inhibition assay Inhibition of human HT cell growth in a cell viability assay, IC50=1.08745μM. SANGER
CHP-212 Growth inhibition assay Inhibition of human CHP-212 cell growth in a cell viability assay, IC50=1.09647μM. SANGER
K052 Growth inhibition assay Inhibition of human K052 cell growth in a cell viability assay, IC50=1.09889μM. SANGER
Calu-3 Growth inhibition assay Inhibition of human Calu-3 cell growth in a cell viability assay, IC50=1.10834μM. SANGER
HH Growth inhibition assay Inhibition of human HH cell growth in a cell viability assay, IC50=1.11763μM. SANGER
OVCAR-5 Growth inhibition assay Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50=1.12389μM. SANGER
SK-MEL-24 Growth inhibition assay Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50=1.13344μM. SANGER
HEC-1 Growth inhibition assay Inhibition of human HEC-1 cell growth in a cell viability assay, IC50=1.13441μM. SANGER
EB-3 Growth inhibition assay Inhibition of human EB-3 cell growth in a cell viability assay, IC50=1.1422μM. SANGER
GCT Growth inhibition assay Inhibition of human GCT cell growth in a cell viability assay, IC50=1.15153μM. SANGER
TYK-nu Growth inhibition assay Inhibition of human TYK-nu cell growth in a cell viability assay, IC50=1.15213μM. SANGER
NOMO-1 Growth inhibition assay Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50=1.15591μM. SANGER
HOP-62 Growth inhibition assay Inhibition of human HOP-62 cell growth in a cell viability assay, IC50=1.16087μM. SANGER
DG-75 Growth inhibition assay Inhibition of human DG-75 cell growth in a cell viability assay, IC50=1.16749μM. SANGER
BE-13 Growth inhibition assay Inhibition of human BE-13 cell growth in a cell viability assay, IC50=1.19523μM. SANGER
OAW-28 Growth inhibition assay Inhibition of human OAW-28 cell growth in a cell viability assay, IC50=1.19821μM. SANGER
ECC4 Growth inhibition assay Inhibition of human ECC4 cell growth in a cell viability assay, IC50=1.20345μM. SANGER
L-428 Growth inhibition assay Inhibition of human L-428 cell growth in a cell viability assay, IC50=1.20502μM. SANGER
LAMA-84 Growth inhibition assay Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50=1.20953μM. SANGER
A673 Growth inhibition assay Inhibition of human A673 cell growth in a cell viability assay, IC50=1.22048μM. SANGER
TK10 Growth inhibition assay Inhibition of human TK10 cell growth in a cell viability assay, IC50=1.22402μM. SANGER
UACC-62 Growth inhibition assay Inhibition of human UACC-62 cell growth in a cell viability assay, IC50=1.22998μM. SANGER
Calu-1 Growth inhibition assay Inhibition of human Calu-1 cell growth in a cell viability assay, IC50=1.23212μM. SANGER
AU565 Growth inhibition assay Inhibition of human AU565 cell growth in a cell viability assay, IC50=1.23981μM. SANGER
KMOE-2 Growth inhibition assay Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50=1.24066μM. SANGER
BHT-101 Growth inhibition assay Inhibition of human BHT-101 cell growth in a cell viability assay, IC50=1.25023μM. SANGER
SW48 Growth inhibition assay Inhibition of human SW48 cell growth in a cell viability assay, IC50=1.25827μM. SANGER
BPH-1 Growth inhibition assay Inhibition of human BPH-1 cell growth in a cell viability assay, IC50=1.25999μM. SANGER
HPAF-II Growth inhibition assay Inhibition of human HPAF-II cell growth in a cell viability assay, IC50=1.26625μM. SANGER
HCC1806 Growth inhibition assay Inhibition of human HCC1806 cell growth in a cell viability assay, IC50=1.27034μM. SANGER
U-87-MG Growth inhibition assay Inhibition of human U-87-MG cell growth in a cell viability assay, IC50=1.27578μM. SANGER
NCI-H460 Growth inhibition assay Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50=1.27769μM. SANGER
CAL-62 Growth inhibition assay Inhibition of human CAL-62 cell growth in a cell viability assay, IC50=1.27999μM. SANGER
TE-8 Growth inhibition assay Inhibition of human TE-8 cell growth in a cell viability assay, IC50=1.28063μM. SANGER
LB2241-RCC Growth inhibition assay Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50=1.28829μM. SANGER
EW-7 Growth inhibition assay Inhibition of human EW-7 cell growth in a cell viability assay, IC50=1.29091μM. SANGER
LU-99A Growth inhibition assay Inhibition of human LU-99A cell growth in a cell viability assay, IC50=1.29565μM. SANGER
NMC-G1 Growth inhibition assay Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50=1.29714μM. SANGER
NCI-H630 Growth inhibition assay Inhibition of human NCI-H630 cell growth in a cell viability assay, IC50=1.3039μM. SANGER
KGN Growth inhibition assay Inhibition of human KGN cell growth in a cell viability assay, IC50=1.30727μM. SANGER
CaR-1 Growth inhibition assay Inhibition of human CaR-1 cell growth in a cell viability assay, IC50=1.30843μM. SANGER
KALS-1 Growth inhibition assay Inhibition of human KALS-1 cell growth in a cell viability assay, IC50=1.31729μM. SANGER
GB-1 Growth inhibition assay Inhibition of human GB-1 cell growth in a cell viability assay, IC50=1.32999μM. SANGER
LoVo Growth inhibition assay Inhibition of human LoVo cell growth in a cell viability assay, IC50=1.33509μM. SANGER
GP5d Growth inhibition assay Inhibition of human GP5d cell growth in a cell viability assay, IC50=1.33776μM. SANGER
EFO-21 Growth inhibition assay Inhibition of human EFO-21 cell growth in a cell viability assay, IC50=1.33859μM. SANGER
NB10 Growth inhibition assay Inhibition of human NB10 cell growth in a cell viability assay, IC50=1.34365μM. SANGER
NCI-H520 Growth inhibition assay Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50=1.35454μM. SANGER
CAL-120 Growth inhibition assay Inhibition of human CAL-120 cell growth in a cell viability assay, IC50=1.36085μM. SANGER
HuP-T4 Growth inhibition assay Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50=1.36178μM. SANGER
SCLC-21H Growth inhibition assay Inhibition of human SCLC-21H cell growth in a cell viability assay, IC50=1.36486μM. SANGER
HN Growth inhibition assay Inhibition of human HN cell growth in a cell viability assay, IC50=1.36764μM. SANGER
NCI-H1650 Growth inhibition assay Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50=1.37503μM. SANGER
JiyoyeP-2003 Growth inhibition assay Inhibition of human JiyoyeP-2003 cell growth in a cell viability assay, IC50=1.38792μM. SANGER
P12-ICHIKAWA Growth inhibition assay Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50=1.38836μM. SANGER
NCI-H1092 Growth inhibition assay Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50=1.39311μM. SANGER
SW13 Growth inhibition assay Inhibition of human SW13 cell growth in a cell viability assay, IC50=1.40919μM. SANGER
CAL-54 Growth inhibition assay Inhibition of human CAL-54 cell growth in a cell viability assay, IC50=1.4199μM. SANGER
TGBC1TKB Growth inhibition assay Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50=1.42819μM. SANGER
U251 Growth inhibition assay Inhibition of human U251 cell growth in a cell viability assay, IC50=1.43246μM. SANGER
CP50-MEL-B Growth inhibition assay Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50=1.43336μM. SANGER
RVH-421 Growth inhibition assay Inhibition of human RVH-421 cell growth in a cell viability assay, IC50=1.46747μM. SANGER
LS-513 Growth inhibition assay Inhibition of human LS-513 cell growth in a cell viability assay, IC50=1.47797μM. SANGER
KOSC-2 Growth inhibition assay Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50=1.49084μM. SANGER
M14 Growth inhibition assay Inhibition of human M14 cell growth in a cell viability assay, IC50=1.49269μM. SANGER
RPMI-8402 Growth inhibition assay Inhibition of human RPMI-8402 cell growth in a cell viability assay, IC50=1.49831μM. SANGER
PC-14 Growth inhibition assay Inhibition of human PC-14 cell growth in a cell viability assay, IC50=1.50716μM. SANGER
CAMA-1 Growth inhibition assay Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50=1.51669μM. SANGER
NCI-H2081 Growth inhibition assay Inhibition of human NCI-H2081 cell growth in a cell viability assay, IC50=1.52477μM. SANGER
NCI-H1437 Growth inhibition assay Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50=1.55748μM. SANGER
SK-OV-3 Growth inhibition assay Inhibition of human SK-OV-3 cell growth in a cell viability assay, IC50=1.5603μM. SANGER
RCC10RGB Growth inhibition assay Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50=1.5639μM. SANGER
Becker Growth inhibition assay Inhibition of human Becker cell growth in a cell viability assay, IC50=1.58222μM. SANGER
KG-1 Growth inhibition assay Inhibition of human KG-1 cell growth in a cell viability assay, IC50=1.59773μM. SANGER
NCI-SNU-1 Growth inhibition assay Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50=1.6022μM. SANGER
SW1990 Growth inhibition assay Inhibition of human SW1990 cell growth in a cell viability assay, IC50=1.61718μM. SANGER
COLO-678 Growth inhibition assay Inhibition of human COLO-678 cell growth in a cell viability assay, IC50=1.62864μM. SANGER
HuO9 Growth inhibition assay Inhibition of human HuO9 cell growth in a cell viability assay, IC50=1.658μM. SANGER
D-247MG Growth inhibition assay Inhibition of human D-247MG cell growth in a cell viability assay, IC50=1.66002μM. SANGER
HCC1937 Growth inhibition assay Inhibition of human HCC1937 cell growth in a cell viability assay, IC50=1.66286μM. SANGER
HT55 Growth inhibition assay Inhibition of human HT55 cell growth in a cell viability assay, IC50=1.68962μM. SANGER
HCC1419 Growth inhibition assay Inhibition of human HCC1419 cell growth in a cell viability assay, IC50=1.68976μM. SANGER
IST-MES1 Growth inhibition assay Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50=1.69661μM. SANGER
TT Growth inhibition assay Inhibition of human TT cell growth in a cell viability assay, IC50=1.69876μM. SANGER
GAMG Growth inhibition assay Inhibition of human GAMG cell growth in a cell viability assay, IC50=1.70971μM. SANGER
NCI-H2141 Growth inhibition assay Inhibition of human NCI-H2141 cell growth in a cell viability assay, IC50=1.71156μM. SANGER
NCI-H2170 Growth inhibition assay Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50=1.71723μM. SANGER
MDA-MB-361 Growth inhibition assay Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50=1.73236μM. SANGER
OMC-1 Growth inhibition assay Inhibition of human OMC-1 cell growth in a cell viability assay, IC50=1.74888μM. SANGER
D-336MG Growth inhibition assay Inhibition of human D-336MG cell growth in a cell viability assay, IC50=1.74977μM. SANGER
SN12C Growth inhibition assay Inhibition of human SN12C cell growth in a cell viability assay, IC50=1.76258μM. SANGER
FADU Growth inhibition assay Inhibition of human FADU cell growth in a cell viability assay, IC50=1.76639μM. SANGER
MS-1 Growth inhibition assay Inhibition of human MS-1 cell growth in a cell viability assay, IC50=1.77248μM. SANGER
NCI-H748 Growth inhibition assay Inhibition of human NCI-H748 cell growth in a cell viability assay, IC50=1.78246μM. SANGER
SK-N-AS Growth inhibition assay Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50=1.7862μM. SANGER
MC116 Growth inhibition assay Inhibition of human MC116 cell growth in a cell viability assay, IC50=1.78636μM. SANGER
SK-N-DZ Growth inhibition assay Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50=1.8032μM. SANGER
OE33 Growth inhibition assay Inhibition of human OE33 cell growth in a cell viability assay, IC50=1.81321μM. SANGER
PLC-PRF-5 Growth inhibition assay Inhibition of human PLC-PRF-5 cell growth in a cell viability assay, IC50=1.81579μM. SANGER
SUP-T1 Growth inhibition assay Inhibition of human SUP-T1 cell growth in a cell viability assay, IC50=1.82291μM. SANGER
BOKU Growth inhibition assay Inhibition of human BOKU cell growth in a cell viability assay, IC50=1.87488μM. SANGER
Caov-4 Growth inhibition assay Inhibition of human Caov-4 cell growth in a cell viability assay, IC50=1.88419μM. SANGER
CAL-12T Growth inhibition assay Inhibition of human CAL-12T cell growth in a cell viability assay, IC50=1.90222μM. SANGER
LB831-BLC Growth inhibition assay Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50=1.9168μM. SANGER
HL-60 Growth inhibition assay Inhibition of human HL-60 cell growth in a cell viability assay, IC50=1.92305μM. SANGER
HuH-7 Growth inhibition assay Inhibition of human HuH-7 cell growth in a cell viability assay, IC50=1.95526μM. SANGER
CAL-33 Growth inhibition assay Inhibition of human CAL-33 cell growth in a cell viability assay, IC50=2.00004μM. SANGER
RCM-1 Growth inhibition assay Inhibition of human RCM-1 cell growth in a cell viability assay, IC50=2.00219μM. SANGER
HCC70 Growth inhibition assay Inhibition of human HCC70 cell growth in a cell viability assay, IC50=2.00836μM. SANGER
HOP-92 Growth inhibition assay Inhibition of human HOP-92 cell growth in a cell viability assay, IC50=2.01024μM. SANGER
NCI-H1618 Growth inhibition assay Inhibition of human NCI-H1618 cell growth in a cell viability assay, IC50=2.01966μM. SANGER
HEL Growth inhibition assay Inhibition of human HEL cell growth in a cell viability assay, IC50=2.04304μM. SANGER
MDA-MB-175-VII Growth inhibition assay Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50=2.05307μM. SANGER
SK-CO-1 Growth inhibition assay Inhibition of human SK-CO-1 cell growth in a cell viability assay, IC50=2.0549μM. SANGER
P31-FUJ Growth inhibition assay Inhibition of human P31-FUJ cell growth in a cell viability assay, IC50=2.06609μM. SANGER
IA-LM Growth inhibition assay Inhibition of human IA-LM cell growth in a cell viability assay, IC50=2.0805μM. SANGER
J-RT3-T3-5 Growth inhibition assay Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50=2.08636μM. SANGER
EHEB Growth inhibition assay Inhibition of human EHEB cell growth in a cell viability assay, IC50=2.09447μM. SANGER
23132-87 Growth inhibition assay Inhibition of human 23132-87 cell growth in a cell viability assay, IC50=2.1083μM. SANGER
HSC-4 Growth inhibition assay Inhibition of human HSC-4 cell growth in a cell viability assay, IC50=2.11883μM. SANGER
A3-KAW Growth inhibition assay Inhibition of human A3-KAW cell growth in a cell viability assay, IC50=2.14029μM. SANGER
MKN7 Growth inhibition assay Inhibition of human MKN7 cell growth in a cell viability assay, IC50=2.20551μM. SANGER
D-263MG Growth inhibition assay Inhibition of human D-263MG cell growth in a cell viability assay, IC50=2.23007μM. SANGER
MDA-MB-415 Growth inhibition assay Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50=2.27674μM. SANGER
NCI-H1703 Growth inhibition assay Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50=2.29723μM. SANGER
SIMA Growth inhibition assay Inhibition of human SIMA cell growth in a cell viability assay, IC50=2.31843μM. SANGER
TE-12 Growth inhibition assay Inhibition of human TE-12 cell growth in a cell viability assay, IC50=2.34325μM. SANGER
NCI-H187 Growth inhibition assay Inhibition of human NCI-H187 cell growth in a cell viability assay, IC50=2.35932μM. SANGER
Saos-2 Growth inhibition assay Inhibition of human Saos-2 cell growth in a cell viability assay, IC50=2.36735μM. SANGER
CP66-MEL Growth inhibition assay Inhibition of human CP66-MEL cell growth in a cell viability assay, IC50=2.39667μM. SANGER
KYSE-70 Growth inhibition assay Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50=2.41566μM. SANGER
NB5 Growth inhibition assay Inhibition of human NB5 cell growth in a cell viability assay, IC50=2.43263μM. SANGER
ETK-1 Growth inhibition assay Inhibition of human ETK-1 cell growth in a cell viability assay, IC50=2.44568μM. SANGER
T-24 Growth inhibition assay Inhibition of human T-24 cell growth in a cell viability assay, IC50=2.46232μM. SANGER
EGI-1 Growth inhibition assay Inhibition of human EGI-1 cell growth in a cell viability assay, IC50=2.51108μM. SANGER
MDA-MB-453 Growth inhibition assay Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50=2.51894μM. SANGER
BT-20 Growth inhibition assay Inhibition of human BT-20 cell growth in a cell viability assay, IC50=2.5613μM. SANGER
A2780 Growth inhibition assay Inhibition of human A2780 cell growth in a cell viability assay, IC50=2.56245μM. SANGER
NCI-H719 Growth inhibition assay Inhibition of human NCI-H719 cell growth in a cell viability assay, IC50=2.61126μM. SANGER
ES5 Growth inhibition assay Inhibition of human ES5 cell growth in a cell viability assay, IC50=2.63445μM. SANGER
NCI-H526 Growth inhibition assay Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50=2.63652μM. SANGER
SK-MEL-3 Growth inhibition assay Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50=2.64221μM. SANGER
GDM-1 Growth inhibition assay Inhibition of human GDM-1 cell growth in a cell viability assay, IC50=2.67606μM. SANGER
C32 Growth inhibition assay Inhibition of human C32 cell growth in a cell viability assay, IC50=2.67789μM. SANGER
BC-1 Growth inhibition assay Inhibition of human BC-1 cell growth in a cell viability assay, IC50=2.6814μM. SANGER
COLO-741 Growth inhibition assay Inhibition of human COLO-741 cell growth in a cell viability assay, IC50=2.69421μM. SANGER
A704 Growth inhibition assay Inhibition of human A704 cell growth in a cell viability assay, IC50=2.70466μM. SANGER
NCI-H1623 Growth inhibition assay Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50=2.72721μM. SANGER
LS-1034 Growth inhibition assay Inhibition of human LS-1034 cell growth in a cell viability assay, IC50=2.74715μM. SANGER
MOLT-16 Growth inhibition assay Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50=2.76298μM. SANGER
NCI-H1355 Growth inhibition assay Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50=2.82251μM. SANGER
RO82-W-1 Growth inhibition assay Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50=2.84295μM. SANGER
NCI-H1993 Growth inhibition assay Inhibition of human NCI-H1993 cell growth in a cell viability assay, IC50=2.94026μM. SANGER
NCI-N87 Growth inhibition assay Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50=2.9423μM. SANGER
TE-6 Growth inhibition assay Inhibition of human TE-6 cell growth in a cell viability assay, IC50=2.96791μM. SANGER
8505C Growth inhibition assay Inhibition of human 8505C cell growth in a cell viability assay, IC50=3.09947μM. SANGER
KURAMOCHI Growth inhibition assay Inhibition of human KURAMOCHI cell growth in a cell viability assay, IC50=3.15936μM. SANGER
JEG-3 Growth inhibition assay Inhibition of human JEG-3 cell growth in a cell viability assay, IC50=3.17165μM. SANGER
KU-19-19 Growth inhibition assay Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50=3.18307μM. SANGER
LS-411N Growth inhibition assay Inhibition of human LS-411N cell growth in a cell viability assay, IC50=3.18961μM. SANGER
LAN-6 Growth inhibition assay Inhibition of human LAN-6 cell growth in a cell viability assay, IC50=3.21916μM. SANGER
JAR Growth inhibition assay Inhibition of human JAR cell growth in a cell viability assay, IC50=3.26295μM. SANGER
LXF-289 Growth inhibition assay Inhibition of human LXF-289 cell growth in a cell viability assay, IC50=3.27156μM. SANGER
LB2518-MEL Growth inhibition assay Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50=3.28331μM. SANGER
IM-9 Growth inhibition assay Inhibition of human IM-9 cell growth in a cell viability assay, IC50=3.41207μM. SANGER
Daudi Growth inhibition assay Inhibition of human Daudi cell growth in a cell viability assay, IC50=3.44287μM. SANGER
BFTC-909 Growth inhibition assay Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50=3.62783μM. SANGER
EKVX Growth inhibition assay Inhibition of human EKVX cell growth in a cell viability assay, IC50=3.67407μM. SANGER
JVM-2 Growth inhibition assay Inhibition of human JVM-2 cell growth in a cell viability assay, IC50=3.86813μM. SANGER
TE-11 Growth inhibition assay Inhibition of human TE-11 cell growth in a cell viability assay, IC50=4.01426μM. SANGER
RERF-LC-MS Growth inhibition assay Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50=4.18997μM. SANGER
D-502MG Growth inhibition assay Inhibition of human D-502MG cell growth in a cell viability assay, IC50=4.36548μM. SANGER
SKG-IIIa Growth inhibition assay Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50=4.38827μM. SANGER
HuO-3N1 Growth inhibition assay Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50=4.43341μM. SANGER
GOTO Growth inhibition assay Inhibition of human GOTO cell growth in a cell viability assay, IC50=4.58835μM. SANGER
22RV1 Growth inhibition assay Inhibition of human 22RV1 cell growth in a cell viability assay, IC50=4.61494μM. SANGER
ES4 Growth inhibition assay Inhibition of human ES4 cell growth in a cell viability assay, IC50=4.63459μM. SANGER
NCI-H2227 Growth inhibition assay Inhibition of human NCI-H2227 cell growth in a cell viability assay, IC50=4.88699μM. SANGER
L-540 Growth inhibition assay Inhibition of human L-540 cell growth in a cell viability assay, IC50=4.90004μM. SANGER
MFE-280 Growth inhibition assay Inhibition of human MFE-280 cell growth in a cell viability assay, IC50=4.94654μM. SANGER
UACC-812 Growth inhibition assay Inhibition of human UACC-812 cell growth in a cell viability assay, IC50=5.07715μM. SANGER
DOK Growth inhibition assay Inhibition of human DOK cell growth in a cell viability assay, IC50=5.18518μM. SANGER
NCI-H661 Growth inhibition assay Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50=5.42873μM. SANGER
SJSA-1 Growth inhibition assay Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50=5.52533μM. SANGER
SF268 Growth inhibition assay Inhibition of human SF268 cell growth in a cell viability assay, IC50=5.57743μM. SANGER
FTC-133 Growth inhibition assay Inhibition of human FTC-133 cell growth in a cell viability assay, IC50=5.74315μM. SANGER
COLO-668 Growth inhibition assay Inhibition of human COLO-668 cell growth in a cell viability assay, IC50=6.19613μM. SANGER
Hs-578-T Growth inhibition assay Inhibition of human Hs-578-T cell growth in a cell viability assay, IC50=6.2234μM. SANGER
LU-139 Growth inhibition assay Inhibition of human LU-139 cell growth in a cell viability assay, IC50=6.26409μM. SANGER
SK-MES-1 Growth inhibition assay Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50=6.28632μM. SANGER
SK-MEL-2 Growth inhibition assay Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50=6.3289μM. SANGER
DJM-1 Growth inhibition assay Inhibition of human DJM-1 cell growth in a cell viability assay, IC50=6.38723μM. SANGER
NCI-H69 Growth inhibition assay Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50=6.7138μM. SANGER
NCI-H1734 Growth inhibition assay Inhibition of human NCI-H1734 cell growth in a cell viability assay, IC50=6.89511μM. SANGER
LN-405 Growth inhibition assay Inhibition of human LN-405 cell growth in a cell viability assay, IC50=6.91468μM. SANGER
SK-N-FI Growth inhibition assay Inhibition of human SK-N-FI cell growth in a cell viability assay, IC50=7.69354μM. SANGER
ES6 Growth inhibition assay Inhibition of human ES6 cell growth in a cell viability assay, IC50=7.87852μM. SANGER
LK-2 Growth inhibition assay Inhibition of human LK-2 cell growth in a cell viability assay, IC50=8.57071μM. SANGER
SW1463 Growth inhibition assay Inhibition of human SW1463 cell growth in a cell viability assay, IC50=8.60636μM. SANGER
NCI-SNU-5 Growth inhibition assay Inhibition of human NCI-SNU-5 cell growth in a cell viability assay, IC50=9.53671μM. SANGER
ECC12 Growth inhibition assay Inhibition of human ECC12 cell growth in a cell viability assay, IC50=9.64824μM. SANGER
DK-MG Growth inhibition assay Inhibition of human DK-MG cell growth in a cell viability assay, IC50=9.8175μM. SANGER
KARPAS-45 Growth inhibition assay Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50=9.98905μM. SANGER
RT4 Growth inhibition assay Inhibition of human RT4 cell growth in a cell viability assay, IC50=10.1219μM. SANGER
PANC-08-13 Growth inhibition assay Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50=10.4305μM. SANGER
DSH1 Growth inhibition assay Inhibition of human DSH1 cell growth in a cell viability assay, IC50=10.5842μM. SANGER
WM-115 Growth inhibition assay Inhibition of human WM-115 cell growth in a cell viability assay, IC50=10.6442μM. SANGER
NCI-H1648 Growth inhibition assay Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50=11.1474μM. SANGER
GMS-10 Growth inhibition assay Inhibition of human GMS-10 cell growth in a cell viability assay, IC50=11.4946μM. SANGER
SW948 Growth inhibition assay Inhibition of human SW948 cell growth in a cell viability assay, IC50=11.909μM. SANGER
SBC-1 Growth inhibition assay Inhibition of human SBC-1 cell growth in a cell viability assay, IC50=12.1492μM. SANGER
NCI-H209 Growth inhibition assay Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50=12.3094μM. SANGER
SNU-475 Growth inhibition assay Inhibition of human SNU-475 cell growth in a cell viability assay, IC50=14.0589μM. SANGER
KINGS-1 Growth inhibition assay Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50=14.0775μM. SANGER
T84 Growth inhibition assay Inhibition of human T84 cell growth in a cell viability assay, IC50=14.5203μM. SANGER
EW-24 Growth inhibition assay Inhibition of human EW-24 cell growth in a cell viability assay, IC50=14.5927μM. SANGER
IST-MEL1 Growth inhibition assay Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50=14.9554μM. SANGER
NCI-H2126 Growth inhibition assay Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50=15.6454μM. SANGER
HCC1395 Growth inhibition assay Inhibition of human HCC1395 cell growth in a cell viability assay, IC50=15.6867μM. SANGER
Calu-6 Growth inhibition assay Inhibition of human Calu-6 cell growth in a cell viability assay, IC50=15.732μM. SANGER
TE-1 Growth inhibition assay Inhibition of human TE-1 cell growth in a cell viability assay, IC50=15.7965μM. SANGER
NCI-H441 Growth inhibition assay Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50=15.8089μM. SANGER
HC-1 Growth inhibition assay Inhibition of human HC-1 cell growth in a cell viability assay, IC50=17.2155μM. SANGER
SiHa Growth inhibition assay Inhibition of human SiHa cell growth in a cell viability assay, IC50=18.6017μM. SANGER
KNS-42 Growth inhibition assay Inhibition of human KNS-42 cell growth in a cell viability assay, IC50=18.6584μM. SANGER
SW837 Growth inhibition assay Inhibition of human SW837 cell growth in a cell viability assay, IC50=19.7841μM. SANGER
LB771-HNC Growth inhibition assay Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50=20.788μM. SANGER
DMS-53 Growth inhibition assay Inhibition of human DMS-53 cell growth in a cell viability assay, IC50=21.4567μM. SANGER
NCI-H1838 Growth inhibition assay Inhibition of human NCI-H1838 cell growth in a cell viability assay, IC50=22.4348μM. SANGER
NCI-H1651 Growth inhibition assay Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50=22.7503μM. SANGER
CPC-N Growth inhibition assay Inhibition of human CPC-N cell growth in a cell viability assay, IC50=24.2624μM. SANGER
SNU-C2B Growth inhibition assay Inhibition of human SNU-C2B cell growth in a cell viability assay, IC50=24.9268μM. SANGER
UACC-257 Growth inhibition assay Inhibition of human UACC-257 cell growth in a cell viability assay, IC50=26.3566μM. SANGER
KARPAS-422 Growth inhibition assay Inhibition of human KARPAS-422 cell growth in a cell viability assay, IC50=26.6117μM. SANGER
NCI-H2122 Growth inhibition assay Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50=27.5539μM. SANGER
DMS-153 Growth inhibition assay Inhibition of human DMS-153 cell growth in a cell viability assay, IC50=27.8083μM. SANGER
TGBC24TKB Growth inhibition assay Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50=27.8827μM. SANGER
Detroit562 Growth inhibition assay Inhibition of human Detroit562 cell growth in a cell viability assay, IC50=29.296μM. SANGER
NCI-H1755 Growth inhibition assay Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50=30.2521μM. SANGER
NCI-H322M Growth inhibition assay Inhibition of human NCI-H322M cell growth in a cell viability assay, IC50=32.4816μM. SANGER
CTV-1 Growth inhibition assay Inhibition of human CTV-1 cell growth in a cell viability assay, IC50=32.7529μM. SANGER
ESS-1 Growth inhibition assay Inhibition of human ESS-1 cell growth in a cell viability assay, IC50=34.1399μM. SANGER
NCI-H23 Growth inhibition assay Inhibition of human NCI-H23 cell growth in a cell viability assay, IC50=34.983μM. SANGER
DMS-114 Growth inhibition assay Inhibition of human DMS-114 cell growth in a cell viability assay, IC50=35.5412μM. SANGER
BB49-HNC Growth inhibition assay Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50=38.5847μM. SANGER
NCI-H446 Growth inhibition assay Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50=39.5543μM. SANGER
LNCaP-Clone-FGC Growth inhibition assay Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50=41.5939μM. SANGER
HCC2998 Growth inhibition assay Inhibition of human HCC2998 cell growth in a cell viability assay, IC50=46.0351μM. SANGER
UMC-11 Growth inhibition assay Inhibition of human UMC-11 cell growth in a cell viability assay, IC50=46.7921μM. SANGER
HT-29 Cytotoxicity assay Cytotoxicity against human HT-29 cells by MTT assay, IC50=16.7μM. 18996624
SPC-A1 Cytotoxicity assay Cytotoxicity against human SPC-A1 cells by MTT assay, IC50=18.1μM. 18996624
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50=0.44μM. 19111464
HeLa Cytotoxicity assay Cytotoxicity agaisnt human HeLa cells by SRB assay, IC50=13.39μM. 19111464
HepG2 Function assay HARVARD: Inhibition of liver stage Plasmodium berghei infection in HepG2 cells, IC50=1.37μM. 22586124
K562 Cytotoxicity assay Cytotoxicity against human K562 cells by MTT assay, IC50=0.7μM. 25127868
fibroblast cells Cytotoxicity assay Cytotoxicity against human skin fibroblast cells by MTT assay, IC50=1.2μM. 25127868
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50=1.8μM. 25127868
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells by MTT assay, IC50=16μM. 25127868
点击查看更多细胞系数据

生物活性

产品描述 Shikonin是一种 Pyruvate kinase M2 (PKM2) 有效的、特异的抑制剂。它是紫草的主要成分,紫草是一种中草药,具有多种生物活性。在细胞荧光淬灭试验中,Shikonin也是TMEM16A氯离子通道的抑制剂。Shikonin 通过抑制 tumor necrosis factor-α (TNF-α) 发挥抗炎作用,并可通过抑制 proteasome 来阻止 nuclear factor-κB (NF-κB) 信号途径的激活。
靶点
chemokine receptor [1] TNF-α [4] Proteasome [4] NF-κB [1] PKM2 [3]
(FBP absence)
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0.3 μM
体外研究(In Vitro)
体外研究活性

在摩尔浓度下,shikonin在多种CC趋化因子(CCL2单核细胞趋化蛋白1), CCL3(巨噬细胞炎性蛋白1α),CCL5(活性调节蛋白,正常T细胞表达并分泌的蛋白),CXC趋化因子(CXCL12基质细胞衍生因子1α)以及经典的化学引诱物的影响的情况下抑制单核细胞趋化性以及钙流动。Shikonin下调巨噬细胞表面CCR5(主要的HIV-1协同受体)的表达。Shikonin 的抗HIV和抗炎症活性可能与它干扰趋化因子受体的表达和功能相关[1]。Shikonin抑制肠上皮细胞钙激活的氯离子通道,这一抑制效应部分通过抑制基地侧的钾离子通道活性来实现[2]

细胞实验 细胞系 人单核细胞
浓度 10, 1, 0.1, 0.01 μM
孵育时间 12和24小时
方法

将新鲜分离的人单核细胞以105/孔的密度铺于96孔板中,加入终浓度为10, 1, 0.1, 0.01 μM的shikonin。孵育12或24小时后(37℃,5% CO2),活细胞的数量用MTS实验和台盼蓝拒染法检测。

实验图片 检测方法 检测指标 实验图片 PMID
Western blot Bcl2 / Bax / CytC / Apaf1 / AIF / Caspase-9 / Caspase-3 / Caspase-7 p-PERK / PERK / p-eIF2α / eIF2α / GRP78 / CHOP MMP-2 / MMP-9 p-β-catenin / β-catenin 25879420
Growth inhibition assay Cell viability 25879420
体内研究(In Vivo)
体内研究活性

Shikonin在小鼠中显著延迟肠动力、在具有轮状病毒腹泻症状的新生小鼠模型中减少粪便含水量,而不影响病毒感染过程。Shikonin被报导具有抗氧化、抗菌、抗寄生物、抗病毒和伤口愈合活性。Shikonin在体内抑制过敏作用和气管高反应性。腹腔注射shikonin会导致一些毒性作用,LD50为20 mg/kg。如果通过口服和肌肉注射给药,shikonin的吸收速度很快,在给药后1分钟,在血浆中很少能检测shikonin。口服shikonin的生物利用度为34%[2]

动物实验 Animal Models ICR新生小鼠
Dosages 0.4 和 1.7 μg/30 μL PBS
Administration 口服

化学信息&溶解度

分子量 288.30 分子式

C16H16O5

CAS号 54952-43-1 SDF Download Shikonin SDF
储存条件(自收到货起)

体外溶解度
批次:

DMSO : 57 mg/mL ( 197.71 mM; DMSO吸湿会降低化合物溶解度,请使用新开封DMSO)

Ethanol : 15 mg/mL

Water : Insoluble

摩尔浓度计算器

体内溶解度
批次:

现配现用,请按从左到右的顺序依次添加,澄清后再加入下一溶剂

动物体内配方计算器

实验计算

摩尔浓度计算器

质量 浓度 体积 分子量

动物体内配方计算器(澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)

mg/kg g μL

第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)

% DMSO % % Tween 80 % ddH2O
%DMSO %

计算结果:

工作液浓度: mg/ml;

DMSO母液配制方法: mg 药物溶于μL DMSO溶液(母液浓度mg/mL,:如该浓度超过该批次药物DMSO溶解度,请先联系Selleck);

体内配方配制方法:μL DMSO母液,加入μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入μL ddH2O,混匀澄清。

体内配方配制方法:μL DMSO母液,加入μL Corn oil,混匀澄清。

注意:1. 首先保证母液是澄清的;
2.一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。

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