Anti-infection

抑制剂选择性比较

Anti-infection产品

所有产品 Anti-infection抑制剂(57) Anti-infection化学产品(457) 新Anti-infection产品

目录号	产品描述	文献引用	实验数据
S2430^New	Azodicarbonamide Azodicarbonamide是第一个已知的通过靶向 nucleocapsid CCHC domains 来抑制 HIV-1 和多种逆转录病毒的核衣壳抑制剂。在标准的基于细胞的抗病毒试验中，Azodicarbonamide抑制HIV-1_RF诱导的CEM-SS细胞病变，EC50为38 µM。
S6689^New	Merimepodib Merimepodib是一种有效、特异性和可逆的inosine monophosphate dehydrogenase(IMPDH)抑制剂，在体外对丙型肝炎病毒(HCV)和多种DNA和RNA病毒具有抗病毒活性。Merimepodib是一种免疫抑制剂。
S6771^New	MAC-545496 MAC-545496是一种纳摩尔浓度的glycopeptide-resistance-associated protein R(GraR)抑制剂，对全长GraR蛋白(Kd≤0.1 nM)具有很强的结合亲和力。 MAC-545496可以逆转耐甲氧西林菌株中的β-内酰胺耐药性，并与CAMP协同作用。 MAC-545496在巨噬细胞中显示出显着的活性，并减弱了苜蓿根瘤菌幼虫感染模型中的金黄色葡萄球菌毒力。
S8932^New	Remdesivir (GS-5734) Remdesivir是腺苷类似物的单磷酰胺酸盐前药，是一种研究性的广谱抗病毒剂，对多种RNA病毒（包括埃博拉病毒和CoV病毒）具有体外活性。
S6676^New	Ebselen Ebselen是HIV-1复制的小分子衣壳抑制剂，在TR-FRET分析中的IC50为46.1 nM。
S6549^New	PBTZ169 PBTZ169是DprE1的不可逆性抑制剂，是一种抗生素。	Cell Death Dis, 2019, 10(4):319
S8873^New	Letermovir（AIC246） Letermovir(AIC246, MK-8228)是新型的anti-CMV化合物，靶向病毒末端酶复合体，对DNA聚合酶抑制剂具有抗性的病毒也具有活性。
S5952^New	Baloxavir marboxil Baloxavir marboxil是一种抗病毒药物，是限制内切核酸酶抑制剂。
S2597	Oseltamivir Phosphate Oseltamivir Phosphate 是一种有效的和选择性的，甲型流感和乙型流感病毒复制必需的神经氨酸酶的抑制剂，用于治疗流行性感冒。	Infect Immun, 2015, 10.1128/IAI.03118-14	Nystatin, filipin III, and oseltamivir inhibit the labeling of trophozoites by CTXB and GM1 antibodies. (A) Trophozoites were treated with nystatin (27 μM), filipin III (7.6 μM), and oseltamivir (20 μM) for 30 min before labeling with Alexa Fluor-conjugated CTXB antibody (images a to d) and GM1 antibody (images a′ to d′). Myriocin (27 μM), a sphingolipid inhibitor, was used as a negative control (images e and e′). N, nucleus; PM, plasma membrane; F, flagella; VD, ventral disc. Bars, 5 μm. (B and C) Changes in intensity of control and inhibitor-treated trophozoites. For intensity measurements, cells were randomly selected from 10 to 15 fields from 3 to 5 separate experiments. Approximately 50 cells were considered for each condition and were analyzed using Zeiss Zen 2009 confocal software. One-way ANOVAs were performed to evaluate differences (means ± SDs) between the treatment and control groups. Mean intensities from 3 to 5 separate experiments are shown in panels B and C. Statistical significance was calculated using a one-way ANOVA test, followed by the Tukey (B) and Holm-Šídák (C) methods. , P < 0.05; , P < 0.01; **, P < 0.001; NS, not significant.
S2527	Methacycline HCl Methacycline HCl 是一种四环素类抗生素，同时也是表皮间质转换的抑制剂（IC50=5 μM），用于治疗各种感染。	Sci Rep, 2018, 8(1):7653
S1677	Chloramphenicol Chloramphenicol是通过抑制蛋白质的合成的抑菌剂。
S2716	Peramivir Trihydrate Peramivir三水合物是抗感染剂Peramivir（RWJ-270201，BCX-1812)的三水合物，这是一种过渡状态模拟和一个强有力的流感病毒神经氨酸酶特异抑制剂,IC50中位数为0.09 nM。	Emerg Microbes Infec, 2014, 3, e78 Emerg Microbes Infect, 2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of peramivir (C) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S1606	Clotrimazole Clotrimazole是一种合成的抗真菌药物，是imidazole的广谱衍生物。	J Biol Chem, 2018, 293(1):333-344
S1956	Miconazole Nitrate Miconazole Nitrate是一种咪唑类抗真菌剂，外用或静脉输液。	Cell Death Dis, 2019, 10(6):413 FASEB J, 2019, 10.1096/fj.201802603RR
S2557	Terbinafine HCl Terbinafine HCl 通过抑制角鲨烯环氧酶抑制了麦角固醇的合成，用作抗真菌药物。
S2457	Clindamycin HCl Clindamycin HCl 是Clindamycin的水合盐酸盐，是一种半合成的抗生素。
S1611	Cefoperazone Cefoperazone是一种头孢菌素类抗生素，能抑制rMrp2调节的17βG的吸收[³ H]E₂，其IC50是199 μM。
S3007	Zanamivir Zanamivir是神经氨酸酶抑制剂，用于治疗A型流感病毒和B型流感病毒引起的流感的治疗。	Emerg Microbes Infec, 2014, 3, e78 Emerg Microbes Infect, 2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of oseltamivir zanamivir (B) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S2908	Hygromycin B Hygromycin B是选择性抗生素，有效作用于大多数细菌，真菌，和更高等的真核生物，通过干扰易位，抑制蛋白合成，造成70S核糖体的错译。	Mol Pharmacol, 2019, 96(1):13-25
S1854	Bifonazole Bifonazole 是一种抗真菌剂和前列腺芳香化酶抑制剂，IC50为1.6 μM。	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S1876	Valaciclovir HCl Valaciclovir HCl 是一种抗病毒药，用于治疗单纯疱疹，带状疱疹，疱疹B。
S1997	Liranaftate Liranaftate 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。
S4042	Nafcillin Sodium Nafcillin sodium可逆的抑制 β-内酰胺酶，K_d为33 mM。
S1791	Bacitracin Zinc Bacitracin是一种抗生素，能够干扰C55-isoprenyl pyrophosphate的去磷酸化，C55-isoprenyl pyrophosphate是一种膜载体分子，参与转运构成肽聚糖细菌细胞壁内膜外部成分。Bacitracin抑制甲硫啡肽中Tyr的裂解，IC50为10 μM。
S2572	Streptomycin sulfate Streptomycin sulfate是Streptomycin的硫酸盐形式，是一种蛋白质合成抑制剂。
S1685	Sulfanilamide Sulfanilamide是细菌酶中二氢喋呤合成的适度竞争性抑制剂，IC50为320 μM。
S8279	Shikonin Shikonin，是一种Pyruvate kinase M2 (PKM2)有效的、特异的抑制剂。它是紫草的主要成分，紫草是一种中草药，具有多种生物活性。在细胞荧光淬灭试验中，Shikonin也是TMEM16A氯离子通道的抑制剂。	Int J Biol Sci, 2020, 16(1):147-161 JCI Insight, 2019, 4(4) Mol Med Rep, 2018, 18(4):3882-3890
S5268	Solithromycin Solithromycin, belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S7550	Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate，红霉素的衍生物，通过结合于50S核糖体抑制细菌蛋白质合成。
S7784	Fumagillin Fumagillin是一种选择性且有效的甲硫氨酸胺基肽酶2(MetAP2)不可逆抑制剂，用作抗生素治疗微孢子虫病。
S3077	Tazobactam Tazobactam是一种 β-内酰胺酶抑制剂，具有抗细菌活性。它还能抑制D类苯唑西林酶OXA-2。它常和piperacillin或其他β-lactam抗生素结合使用，来扩增其抗生谱并增强抗生效应。
S4647	Cefmenoxime hydrochloride Cefmenoxime, 肠杆菌科的有效抑制剂，是一种头孢菌素抗生素，通常用于静脉注射或肌内注射。
S5499	Amantadine Amantadine is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S4602	Acetohydroxamic acid Acetohydroxamic acid是尿素酶抑制剂。在尿液中，它可作为细菌酶尿素酶的拮抗剂。
S9303	Saikosaponin B2 Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.	Phytomedicine, 2019, 67:153163
S9018	Luteoloside Luteoloside is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
S9063	Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S9064	Trilobatin Trilobatin, a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S5704	Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S9070	Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S4198	Aminothiazole Aminothiazole作为甲状腺抑制剂，具有抗菌活性。
S9072	Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S5927	Proguanil Proguanil是预防性抗疟药。它能抑制疟原虫的二氢叶酸还原酶，阻止嘌呤和嘧啶的合成。
S3710	Fosfomycin calcium Fosfomycin是一种杀菌剂，可通过使UDP-N-acetylglucosamine-3-enolpyruvyltransferase失活而一直细菌细胞壁形成。Fosfomycin可通过甘油磷酸盐转运蛋白进入细胞壁。
S5025	Efinaconazole Efinaconazole是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成，ergosterol是真菌细胞膜的成分之一。
S3667	Imipenem Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.
S4105	Closantel Sodium Closantel Sodium是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S4106	Closantel Closantel是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S3732	Avibactam sodium Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.
S9341	3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S2348	Rotenone (Barbasco) Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport.	Nat Commun, 2019, 10(1):3856
S3028	Geneticin (G418 Sulfate) Geneticin (G418 Sulfate), 一种氨基糖苷类抗生素, 是80 S ribosomes延伸的抑制剂，在原核和真核细胞中均能通过抑制延伸步骤来阻断多肽合成。	Mol Cell, 2019, 75(6):1103-1116.e9 Antiviral Res, 2019, 174:104678
S7417	Puromycin 2HCl Puromycin 2HCl 是一种氨基核苷抗菌素，其可作为蛋白质合成的抑制剂。	Cell Rep, 2020, 30(2):497-509 Cancer Lett, 2020, 469:380-389 J Clin Invest, 2019, 129(6):2333-2350
S4286	Anidulafungin (LY303366) Anidulafungin (LY303366), 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。	Cell Physiol Biochem, 2016, 38(6):2272-84	Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
S4854	Bedaquiline fumarate Bedaquiline fumarate, an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
S1958	Sulbactam Sulbactam 是β-内酰胺酶抑制剂，IC50为0.8 μM。
S4564	Diethylcarbamazine citrate Diethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂，对几种寄生虫高度特异，不含任何有毒金属元素。
S1373	Daptomycin Daptomycin是一种新型抗生素，在体外对革兰氏阳性菌具有快速的杀菌活性。	Biochemistry, 2018, 57(38):5629-5639 Biochem Biophys Res Commun, 2018, 503(3):2033-2039 Front Microbiol, 2018, 9:1175	Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
S1408	Linezolid Linezolid 是一种合成的抗生素，用于治疗严重感染。	J Mol Cell Biol, 2019, pii: mjz020 PLoS One, 2019, 14(10):e0222970 Front Microbiol, 2018, 9:1175
S1097	BTZ043 Racemate BTZ043 Racemate是一种decaprenylphosphoryl-β-D-ribose 2’-epimerase的抑制剂，是一个可以杀死结核杆菌的新的抗分支杆菌的药物。	Biochem Pharmacol, 2019, 162:41-54 Blood Adv, 2019, 3(5):797-812
S1517	Natamycin Natamycin 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。
S1403	Tigecycline Tigecycline 是一种甘氨酰环素类抗生素。	BMC Infect Dis, 2017, 17(1):197 Biochem J, 2016, 473(1):99-107 Nat Med, 2015, 21(2):178-84	CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
S6761^New	Dalfopristin Dalfopristin is a semi-synthetic analogue of ostreogyrcin A, Quinupristin/dalfopristin is a new combination streptogramin product with a selective spectrum of antibacterial activity, mainly against gram-positive aerobic bacteria.
S9466^New	Methenamine Hippurate Methenamine Hippurate是methenamine的马草酸盐形式，是一种前药和惰性弱碱，在酸性尿液中会水解成甲醛。Methenamine Hippurate是Hiprex药物的成分，具有抗菌活性。
S4393^New	Cephapirin Sodium Cephapirin Sodium是cephapirin的钠盐形式，是一种半合成的第一代头孢菌素抗生素，对革兰氏阴性细菌和革兰氏阳性细菌都有效。
S4404^New	Pasiniazid Pasiniazid，由isoniazid和4-aminosalicylic acid组成，用于治疗肺结核患者。
S6729^New	Besifovir Besifovir是新型有效的无环核苷膦酸酯，用于治疗HBV感染。
S4421^New	Josamycin Josamycin是一种来源于那波链霉菌的大环内脂类抗菌素，对一系列的病原体具有广泛的抗菌活性。
S6582^New	Ozenoxacin Ozenoxacin是一种喹诺酮药物，用于治疗脓疱病。
S8871^New	Omadacycline tosylate Omadacycline是氨甲环素类抗生素，对革兰氏阳性和阴性的需氧菌以及一些厌氧菌具有抗菌活性。
S6562^New	KKL-35 KKL-35抑制trans-translation tagging reaction，IC50为0.9 μM。它具有广谱抗生素活性。
S6444^New	Triclocarban Triclocarban是一种常用于个人护理用品中的抗细菌试剂。
S6451^New	Salifungin Salifungin (Bromochlorosalicylanilide)是一种抗真菌剂，在某些个体中可能导致过敏性接触性皮炎。
S6442^New	Chlorphenesin Chlorphenesin是一种合成的防腐剂，被用于护肤品中，是一种化妆品抗微生物剂。
S6464^New	Ftaxilide Ftaxilide是一种新型的抗痨药。
S6459^New	Nifurtimox Nifurtimox是一种抗原虫剂。
S6467^New	Fosfluconazole Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物，用于治疗和组织表面的和系统性真菌感染。
S6461^New	Permethrin Permethrin是一种合成的I型拟除虫菊酯、具有神经毒性的杀虫剂。
S6423^New	Tildipirosin Tildipirosin是一种半合成的大环内脂类抗菌素。	Nat Cell Biol, 2017, 19(10):1274-1285
S6411^New	Nimorazole Nimorazole是一种水溶性的硝基咪唑化合物，具有抗细菌和潜在的放射增敏作用。
S5944^New	Butenafine Butenafine是合成的苄胺抗真菌剂。
S6288^New	Chlorhexidine diacetate Chlorhexidine diacetate是一种消毒剂和局部抗感染剂，也用于漱口水中防止口腔菌斑。
S6408^New	Hexetidine Hexetidine是一种抗细菌和抗真菌剂，具有局部麻醉、止血、除臭、预防牙菌斑作用。
S6235^New	Sodium dehydroacetate Sodium dehydroacetate是无水醋酸的钠盐形式。无水醋酸是一种杀菌剂，通常被用作食品防腐剂。
S1878	Ganciclovir Ganciclovir 是一种抗病毒药，作用于猫科动物1型疱疹病毒，无细胞试验中IC50为5.2 μM。	PLoS One, 2019, 14(6):e0218471 Cell Stem Cell, 2017, 20(3):407-414.e4 Sci Rep, 2017, 7:43349	Effect of ganciclovir on viral DNA accumulation (A,B) and induction of TGF-β1 production after human cytomegalovirus infection in human trabecular meshwork cells (C). Cells were harvested at 5 day post-infection at a high multiplicity of infection (MOI 1) under the treatment with different concentrations of ganciclovir (GAN). Treatment with 10 μmol of ganciclovir significantly decreased the viral DNA accumulation (p < 0.001) (A,B). However, treatment with ganciclovir did not affect the TGF-β production using a TGF-β1 luciferase bioassay. Results are expressed as the mean +/− standard deviation of three different experiments.
S2504	Ribavirin Ribavirin 是一种抗病毒剂，用于治疗重症RSV感染，丙型肝炎病毒感染和其他病毒感染。	Nat Immunol, 2019, 20(12):1681-1691 Phytomedicine, 2018, 42:258-267 Neuron, 2017, 96(6):1290-1302	(E) Left panel, Western blot showed that 20 μM Ribavirin effectively inhibits elevated Sox2 expression in irradiated SW1990 cells. Right panel, qPCR analysis showed that Sox2 mRNA level in irradiated SW1990 cells at 48 hours was lower than that in non-irradiated SW1990 cells, *p < 0.05. (F) Left panel, Western blot showed 20 μM Ribavirin inhibits elevated Sox2 expression in irradiated BxPc-3 cells. Right panel, qPCR analysis showed that there is no significant fluctuation of Sox2 mRNA in irradiated BxPc-3 cells and Ribavirin did not influence sox2 mRNA level in irradiated BxPc-3 cells.
S1807	Aciclovir Acyclovir 是一种合成的核苷类似物，有效作用于疱疹病毒。	Nat Immunol, 2019, 20(12):1681-1691 Sci Adv, 2019, 5(8):eaax0780 Oncol Rep, 2017, 37(4):2109-2120	(A) HONE1 and (B) HK1-EBV cells were treated with TPA (40 ng/ml) and SB (3 mM) for EBV induction. After 3 h, uninduced and induced HONE1 and HK1-EBV cells were treated with the vehicle control (0.006% DMSO) or indicated concentrations of berberine for 48 h. Subsequently, the culture medium was harvested for quantitative-PCR analysis with EBNA1 primers. Each sample was normalized to the amount of the GAPDH gene; *p<0.05, compared with the control group.
S1374	Doripenem Hydrate Doripenem Hydrate 是一种超广谱的，注射用的抗生素。	ACS Chem Biol, 2018, 13(8):2020-2026
S1381	Meropenem Meropenem是一种超广谱的，注射用的抗生素。
S1162	Pretomanid (PA-824) PA-824是一种抗肺结核药，作用于tuberculosis，MIC为<1 μg/mL。Phase 2。
S1934	Nystatin (Fungicidin) Nystatin (Fungicidin) 是一种多烯类抗真菌剂，常常被用作oropharyngeal candidosis的局部治疗剂。	Fish Shellfish Immunol, 2019, 84:138-147 International Journal of Peptide Research and Therapeutics, 2015, 10.1007/s10989-014-9440-x
S1741	Rifabutin Rifabutin 是一种半合成的Ansamycin 抗生素，具有有效的抗分枝杆菌特性。
S1370	Biapenem Biapenem 是一种碳青霉烯类抗生素，抑制了革兰氏阳性菌以及革兰氏阴性菌的活性。
S1351	Ivermectin Ivermectin是一种chloride channel激活剂，用作广谱抗寄生虫药。	Cell Death Dis, 2019, 10(2):118 Mol Cell, 2017, 68(2):323-335
S1371	Cefoselis Sulfate Cefoselis sulfate 是一种抗生素。
S2159	Tebipenem Pivoxil Tebipenem pivoxil是一种新型口服的 Carbapenem抗生素，用于治疗鼻咽喉及呼吸道感染。
S1636	Amphotericin B Amphotericin B（AMB）是两亲多烯抗生素，使含有麦角固醇-膜具有渗透性。
S1282	Artemisinin Artemisinin青蒿素用于治疗耐多药的恶性疟疾菌株。	Biomed Pharmacother, 2019, 117:109181
S1399	Teicoplanin Teicoplanin是一种预防用的抗生素。
S2468	Fenbendazole Fenbendazole 是一种广谱苯并咪唑类驱虫药，作用于胃肠道寄生虫，IC50为0.01 μg/ml。
S1505	Aztreonam Aztreonam 是一种合成的单环β-内酰胺类抗生素。	Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1725	Terbinafine Terbinafine 用于治疗真菌感染，可以杀死真菌或防止其生长。	Eur J Pharm Sci, 2019, 136:104945 BMC Microbiol, 2018, 18(1):203
S2510	Spectinomycin 2HCl Spectinomycin 2HCl是由Streptomyces spectabilis中制备的一种新型的肠道外抗生素。
S1768	Cefditoren Pivoxil Cefditoren pivoxil 是一种广谱的抗生素，用于治疗格兰仕阳性菌和阴性菌感染。
S1450	Nanchangmycin Nanchangmycin是一种聚醚抗生素，与Dianemycin结构相似，非常有效地防治广谱的有害线虫和昆虫，而对哺乳动物和植物没有作用效果。	Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 32(5):686-701 Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 10.1080/19440049.2015.1008588
S1839	Chloroxine Chloroxine是一种人工合成的抗菌化合物，加入洗发液中，有效治疗头皮屑和脂溢性皮炎。
S2264	Artemether Artemether 是一种抗疟药，用于治疗恶性疟疾的耐药菌株。	PLoS Negl Trop Dis, 2015, 9(3):e0003593	Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
S1666	Flucytosine Flucytosine是氟嘧啶类似物, 是抗菌药，作用于人白色念珠菌（C. albicans）时 IC50 为0.12 μg/mL。
S1998	D-Cycloserine D-Cycloserine是氨基酸D-丙氨酸的类似物。
S2479	Lincomycin HCl Lincomycin HCl 是Lincomycin的一水盐, 是Lincolnensis链霉菌属的成员生长所产生的物质。
S1605	Cefdinir Cefdinir 是一种杀菌抗生素。
S3073	Caspofungin Acetate Caspofungin Acetate是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。	J Microbiol Immunol Infect, 2018, 10.1016/j.jmii.2018.04.002 Antimicrob Agents Chemother, 2017, 61(5) Antimicrobial Agents and Chemotherapy, 2016, 10.1128/AAC.02921-15
S2528	Ciclopirox Ciclopirox 是一种合成的抗真菌药物。
S2152	Sitafloxacin Hydrate Sitafloxacin Hydrate是新一代口服的广谱喹诺酮类抗生素。	mSphere, 2018, 3(5) Interact Cardiovasc Thorac Surg, 2018, 10.1093/icvts/ivy209
S1502	Cephalexin Cephalexin是可以治疗许多细菌感染的抗生素。	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1835	Azithromycin Azithromycin是一种抑制蛋白合成的抗生素，用于细菌感染的治疗。	J Med Chem, 2018, 61(9):4189-4202
S1773	Oxytetracycline (Terramycin) Oxytetracycline(Terramycin) 是第二个被发现的广谱四环素类抗生素。	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765	Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
S1637	Docosanol Docosanol是一种饱和脂肪酸，在化妆品领域，作为一种润肤剂，乳化剂，和增稠剂，也是营养补充剂，抑制病毒产生，ED50为1.7 mg/ml。
S2535	Econazole nitrate Econazole nitrate 是一种咪唑类抗真菌药物。
S2568	Neomycin sulfate Neomycin sulfate属于氨基糖苷类抗生素。
S1777	Ethionamide Ethionamide是一种抗生素，用于治疗肺结核。
S1635	Erythromycin Erythromycin是一种大环内酯类抗生素，具有与青霉素类似的或略宽于青霉素的抗菌谱(IC50为1.5 μg/ml)。	J Med Chem, 2018, 61(9):4189-4202
S2420	Aloperine Aloperine是提取自苦参植物，如Sophora alopecuroides L的生物碱，具有抗炎，抗菌，抗病毒,和抗肿瘤的特性。	PeerJ, 2019, 7:e7652 Onco Targets Ther, 2018, 11:2735-2743
S4226	Minocycline HCl Minocycline HCl 是脂溶性的最活跃的四环素类抗生素，结合到30S核糖体亚基，抑制tRNA结合到核糖体mRNA复合物，干扰蛋白质合成。	J Neurosci, 2020, 40(2):297-310 Brain Behav Immun, 2019, S0889-1591(19)30622-1 J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S2486	Moroxydine HCl Moroxydine HCl 是一种合成的抗病毒化合物，属于杂环双胍系列。
S1644	Nitrofural Nitrofural 是外用的抗感染剂，IC50为22.83±1.2 μM，作用于大鼠，LD50为590 mg/kg。
S3079	Atovaquone Atovaquone 用于治疗或预防肺孢子菌肺炎，弓形虫病, 疟疾和巴贝西虫。	Sci Transl Med, 2015, 7(290):290ra89
S4050	Valganciclovir HCl Valganciclovir HCl是一种ganciclovir 的前体药物，具有抗病毒活性，用于治疗巨细胞病毒感染。	Transl Res, 2016, 177:113-126
S4052	Netilmicin Sulfate Netilmicin Sulfate 是一种氨基糖苷类抗生素家族成员。	J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S4082	Spiramycin Spiramycin是16元环大环内酯（抗生素）。
S2565	Amoxicillin Sodium Amoxicillin Sodium是一种中等谱，溶菌，β-内酰胺类抗生素。	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2544	Cefprozil hydrate Cefprozil hydrate 是第二代头孢菌素类抗生素。
S2563	Oxacillin sodium monohydrate Oxacillin sodium monohydrate是一种抗菌剂，是一种窄谱，青霉素类的β-内酰胺类抗生素。
S3129	Trimethoprim Trimethoprim 是一种抑制细菌的抗生素，主要用于预防和治疗尿路感染。
S2028	Diclazuril Diclazuril 是一种抗球虫药。
S3161	Sertaconazole nitrate Sertaconazole nitrate是一种外用广谱抗真菌药，是用来治疗表面皮肤和粘膜感染的辅助用药
S1499	Cefaclor Cefaclor是一种头孢菌素类抗生素。
S1915	Sulfamethoxazole Sulfamethoxazole 是磺胺类抑制细菌的抗生素，IC50为2.7 μM。
S2120	Arbidol HCl Arbidol HCl是一种抗病毒药，用于治疗流感病毒感染。
S2467	Famciclovir Famciclovir 是一种鸟嘌呤类似物抗病毒药物，用于治疗各种疱疹病毒感染。
S2031	Fenticonazole Nitrate Fenticonazole Nitrate 是一种唑类抗真菌药物。
S2574	Tetracycline HCl Tetracycline HCl是Tetracycline的盐酸盐，是一种广谱的聚酮类抗生素。	Sci Rep, 2018, 8(1):7653
S2575	Vancomycin HCl Vancomycin HCl 是Vancomycin的盐酸盐，是一种窄谱的糖肽类抗菌剂。
S1851	Oxibendazole Oxibendazole是一种广谱驱虫药。	Oncol Lett, 2018, 15(2):2218-2226
S2501	Pyrantel Pamoate Pyrantel pamoate是一种广谱驱虫剂，用于治疗一些寄生虫感染。
S4030	Gentamicin Sulfate Gentamycin Sulfate是一种广谱的氨基糖苷类抗生素，用于细胞培养，抑制蛋白合成。
S2514	Tobramycin Tobramycin 是一种氨基糖苷类抗生素，IC50为9.7 μM。
S1762	Pyrazinamide Pyrazinamide 是一种治疗肺结核的药物。
S1676	Amorolfine HCl Amorolfine HCl是一种抗真菌药物。	Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376	b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
S4075	Zinc Pyrithione Zinc Pyrithione是一种抗真菌和抗细菌药物，可以通过阻断质子泵破坏膜转运。	Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2530	7-Aminocephalosporanic acid 7-Aminocephalosporanic acid 是一种中间体，用于合成头孢菌素类抗生素。
S2536	Miconazole Miconazole 是一种咪唑类抗真菌药物。
S2543	Ceftiofur HCl Ceftiofur HCl 是Ceftiofur的盐酸盐，是一种广谱头孢菌素。
S1691	Praziquantel Praziquantel是一种驱虫药，有效作用于扁形虫。	PLoS Negl Trop Dis, 2015, 9(3):e0003593	Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
S4237	Primaquine Diphosphate Primaquine Diphosphate是一种临床有效的阻断传播的抗疟疾药，对人类疟疾的的配子体具有明显的抵抗活性。	Cell Syst, 2019, 8(2):97-108
S1964	Rimantadine Rimantadine 是一种抗流感病毒药物，作用于T. brucei，IC50为7 μM。
S1883	Idoxuridine Idoxuridine 是一种抗病毒药，作用一猫疱疹病毒1型，IC50为4.3 μM。
S3162	Tylosin tartrate Tylosin tartrate是一种大环内酯类抗菌素，用于控制家禽的支原体病。
S1916	Sulfisoxazole Sulfisoxazole 是一种磺胺类抗菌药，具有一个恶唑取代基。
S1770	Sulfadiazine Sulfadiazine 是一种磺胺类抗生素。
S3195	Azlocillin sodium salt Azlocillin sodium salt是一种酰基氨苄青霉素，具有广谱抗菌作用。
S4004	Ethambutol 2HCl Ethambutol是一种抗分枝杆菌抑菌剂, 通过抑制阿拉伯糖基转移酶来干扰细胞壁形成。	Molecules, 2019, 25(1)
S2469	Fleroxacin Fleroxacin 是一种新型广谱喹诺酮类。
S2551	Sulbactam sodium Sulbactam sodium 是不可逆的β-内酰胺酶抑制剂。
S3116	Sulfathiazole Sulfathiazole是一种有机硫化合物，已被用来作为一种短效的磺胺类药物。
S1910	Tioconazole Tioconazole是一种抗真菌药物，IC50为1.7 μM。	Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S2506	Roxithromycin Roxithromycin 是一种半合成的大环内酯类抗生素，用于治疗呼吸道，泌尿及软组织感染。	J Med Chem, 2018, 61(9):4189-4202
S2048	Clindamycin Phosphate Clindamycin Phosphate是一种林可酰胺类抗生素，作用于 Plasmodium falciparum，IC50为12 nM。
S3055	Besifloxacin HCl Besifloxacin HCl是一种第四代氟喹诺酮类抗生素。
S4120	Sulconazole Nitrate Sulconazole Nitrate 是一种咪唑衍生物，具有广谱抗真菌活性。
S2511	Sulfadoxine Sulfadoxine是一种超长效磺胺类药物，作用于P. Vivax，IC50为249 μg/ml。
S3067	Chlorhexidine 2HCl Chlorhexidine HCl是一种防腐剂，可以有效抵抗大多数革兰氏阴性和阳性有机体。
S3059	Enrofloxacin Enrofloxacin是一种氟喹诺酮类抗生素。
S4141	Dinitolmide Dinitolmide 是一种广谱抗球虫的药物。
S1977	Sarafloxacin HCl Sarafloxacin HCl是Sarafloxacin的盐酸盐形式，是一种喹诺酮类抗生素IC50为0.96 μg/L。
S4146	Bacitracin Bacitracin是由Bacillus subtilis var生物体产生的相关环状多肽组成的混合物，通过干扰细胞壁肽聚糖的合成，从而破坏革兰氏阳性和革兰氏阴性细菌。	Chem Res Toxicol, 2017, 30(10):1804-1814
S4147	Azithromycin Dihydrate Azithromycin Dihydrate 是对酸稳定的，口服的，大环内酯类抗菌药物，结构与红霉素相关。
S4044	Toltrazuril Toltrazuril 是一种抗原生动物药剂，对球虫寄生虫有活性。
S4254	Apramycin Sulfate Apramycin是一种氨基糖苷类抗生素，与RNA的深槽结合。
S4056	Retapamulin Retapamulin是一种局部抗生素,可以结合大肠杆菌和金黄色葡萄球菌核糖体，效果类似，K_d值为3 nM.
S3015	Amoxicillin Amoxicillin是一种温和β-内酰胺抗生素，用于治疗敏感菌引起的微生物细菌感染。	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S4184	Penciclovir Penciclovir是一种嘌呤的无环核苷类似物，具有强大的抗病毒活性。
S4191	Betamipron Betamipron是一种化学化合物，与Panipenem一起使用，抑制Panipenem吸收进肾小管，防止肾毒性。
S1957	Sulfamethizole Sulfamethizole 是一种磺胺类抗菌剂。
S2537	Secnidazole Secnidazole 是一种硝基咪唑类抗感染剂。
S4195	Broxyquinoline Broxyquinoline是一种抗原虫剂，作用于粘膜，可以从水中释放氧自由基。
S4196	Ethacridine lactate monohydrate Ethacridine lactate monohydrate是一种芳香族有机化合物，用作防腐剂。	Carcinogenesis, 2014, 35(12):2822-30
S4093	Bismuth Subcitrate Potassium Bismuth Subcitrate是一种抗生素，用于治疗感染幽门螺旋杆菌的胃溃疡。
S4094	Tetramisole HCl Tetramisole是右旋和左旋异构体的混合物，用作驱虫剂。
S2539	Lomefloxacin HCl Lomefloxacin HCl 是Lomefloxacin 的盐酸盐，是一种喹诺酮类抗生素。
S2612	Ribitol Ribitol是一种戊糖醇结晶，通过核糖还原形成，在Adonis vernalis植物中自然发生。
S3122	Amikacin hydrate Amikacin hydrate 是一种氨基糖甙类抗生素，用于治疗不同类型的细菌感染。	Molecules, 2019, 25(1)
S3105	Nadifloxacin Nadifloxacin 是一种有效的具有广谱作用的喹诺酮类外用药物，主要针对痤疮及其它皮肤感染。Nadifloxacin可以抑制参与细菌DNA 合成和复制的DNA促旋酶活性，从而抑制细菌增殖。体外研究表明nadifloxacin具有广谱抗菌作用对好氧的革兰氏阳性菌，革兰氏阴性菌以及厌氧细菌都有效果。此外，研究表明nadifloxacin对于炎症性痤疮病变也有效果，这可能与它对炎症前细胞因子的抑制效果有关，如白细胞介素 (IL)-1α, IL-6以及IL-8 ，这些因子在痤疮发病过程中起到重要作用。
S4234	Capreomycin Sulfate Capreomycin Sulfate是一种环状多肽类抗生素，通过与70S核糖体结合，从而抑制蛋白合成。	Mol Cell Proteomics, 2019, 18(2):231-244
S3133	Sulfamethazine Sulfamethazine是一种磺胺类抗菌药,是一种用来治疗支气管炎，前列腺炎以及尿道感染的抗生素。Sulfamethazine 通过抑制二氢叶酸合成酶活性来阻断二氢叶酸合成。此外， sulfamethazine 是一种对氨基苯甲酸(PABA)的结构类似物和竞争性拮抗剂，可以抑制正常的细菌利用PABA 来合成叶酸，而叶酸是一种重要的DNA合成代谢物。
S1855	Pefloxacin Mesylate Pefloxacin Mesylate是一种合成的化疗药物和抗菌剂，IC50为6.7 nM。
S3154	Butenafine HCl Butenafine HCl是一种合成的苄胺类抗真菌药物，通过抑制甾醇合成，通过抑制角鲨烯环氧酶，而发挥作用。
S3156	Naftifine HCl Naftifine HCl是一种烯丙基胺类抗真菌药，外用治疗足癣，股癣，体癣，通过抑制角鲨烯2,3-环氧酶选择性抑制甾醇的生物合成。
S1833	Butoconazole nitrate Butoconazole nitrate 是一种抗真菌剂，抑制PHA刺激下人外周血淋巴细胞中细胞因子（如IL-2, TNFα, IFN 和 GM-CSF）的分泌，IC50分别为7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。
S3179	Carbenicillin disodium Carbenicillin disodium是一种半合成的青霉素抗生素，可以干扰革兰氏阴性菌细胞壁的合成，具有低毒性。
S3193	Ticarcillin sodium Ticarcillin sodium是一种半合成的抗生素，对多种革兰氏阳性和阴性需氧以及厌氧菌具有广谱杀菌活性。
S1881	Protionamide Protionamide 用于治疗肺结核的一种药。
S1830	Oxfendazole Oxfendazole 是Fenbendazole的亚砜形式，是一种广谱的苯并咪唑类驱虫药。
S4726	Lauric Acid Lauric Acid（月桂酸）是饱和中链脂肪酸，在多种植物、动物油脂中都天然存在，是椰子油和棕榈仁油的主要成分。
S5227	Erythromycin thiocyanate Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits and inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
S3941	Pinocembrin Pinocembrin是制药工业中多功能黄酮类分子，它具有很多药学活性，如抗菌、消炎、抗氧化和抗癌活性。
S5352	Cefminox Sodium Cefminox Sodium is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.
S3621	Pazufloxacin mesylate Pazufloxacin Mesylate，也被称作是Pazucross和T-3762，是一种喹诺酮类抗菌剂，用于多种感染的治疗。
S5560	Midecamycin Midecamycin is a naturally occuring macrolide antibiotic that acts by inhibiting bacterial protein synthesis.
S3999	α-santonin α-santonin, a naturally occurring sesquiterpene lactone, is a potent antiparasitic agent.
S5406	Sultamicillin Tosylate Sultamicillin Tosylate is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.
S5048	Fosfomycin Disodium Fosfomycin是一种具有杀菌活性的，低分子量、广谱抗生素，通过抑制细胞壁合成的早期阶段，对一些细菌具有潜在活性，如多药耐药的革兰氏阴性细菌。
S9200	Pneumocandin B0 Pneumocandin B0 is a natural product and a key intermediate in the synthesis of the antifungal agent.
S5051	Pipemidic acid Pipemidic acid是一类吡啶并嘧啶类抗生素，是piromidic acid的衍生物，对革兰氏阴性和某些革兰氏阳性细菌具有活性。
S5328	Gamithromycin Gamithromycin is a new macrolide antibiotic that is only registered for use in cattle to treat respiratory disorders such as bovine respiratory disease.
S4576	Sulfabenzamide Sulfabenzamide是一种抗菌剂，它通过多种途径也可以发挥抗肿瘤效果。
S5353	Cefpiramide sodium Cefpiramide sodium（SM-1652,wy-44635） is an anionic β-lactam antibiotic. It exhibits antibacterial activity against gram-positive and gram-negative bacteria, in particular, to Pseudomonas aeruginosa, which can result in achronic life-threatening infection in the lungs of cystic fibrosis patients.
S4848	Dalbavancin Dalbavancin是一种脂糖肽类抗生素，对革兰氏阳性菌，如多种葡萄状球菌，具有杀菌活性。
S5081	Ceforanide Ceforanide是一种新型头孢菌素，具有抗细菌活性，具有较长的消除半衰期。
S5951	Cefoxitin Cefoxitin是一种β-内酰胺、头孢菌素抗生素，具有杀菌活性。
S5035	6-Aminopenicillanic acid 6-Aminopenicillanic acid (6-APA)是一种青霉素β-内酰胺抗生素的核心组分。它被用作抗菌化合物ampicillin和amoxicillin的前体。
S5356	Ceftiofur Ceftiofur is a semisynthetic, beta-lactamase-stable, broad-spectrum cephalosporin with antibacterial activity.	Vet J, 2018, 234:24-26
S9564	p-Hydroxy-cinnamic Acid p-Hydroxy-cinnamic Acid在体外具有抗疟活性和体内抗骨质疏松活性。
S4581	Triacetin Triacetin是一种甘油三酸酯，具有杀真菌作用。
S5012	Octenidine Dihydrochloride Octenidine是一种阳离子型表面活性剂，对革兰氏阳性和阴性的细菌具有活性。
S5411	Sultamicillin Sultamicillin is a newly developed antibiotic in which ampicillin and the β-lactamase inhibitor sulbactam are linked as an ester.
S2583	Thiamphenicol Thiamphenicol 是一种抗菌的抗生素，是Chloramphenicol的甲磺酰基类似物。
S3741	Benznidazole Benznidazole是一种硝基咪唑衍生物，能够干扰寄生虫蛋白质的生物合成、影响其细胞因子的产生、刺激宿主的吞噬作用，因而具有抗原虫活性。
S5213	Piroctone Olamine Piroctone Olamine is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S3623	Ceftibuten dihydrate Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity.
S4850	Flucloxacillin sodium Flucloxacillin sodium is the sodium salt of flucloxacillin, a penicillin antibiotic used to treat bacterial infections.
S5553	Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S9224	Dehydroandrographolide Succinate Dehydroandrographolide succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, has antibacterial and antiviral effects.
S4846	Meropenem Trihydrate Meropenem is a broad-spectrum antibacterial agent of the carbapenem family with a broad spectrum of in vitro activity against Gram-positive and Gram-negative pathogens.
S5533	Tobramycin sulfate Tobramycin sulfate is the sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces tenebrarius with bactericidal activity.
S9226	Steviolbioside Steviolbioside, a natural sweetener, exhibits moderate antituberculosis activity against M. tuberculosis strain H37RV in vitro.
S4594	Cephalothin Cephalothin是一种半合成的β-内酰胺类抗生素，第一代头孢菌素抗生素，具有杀菌活性。Cephalothin与位于细菌细胞壁内膜的青霉素结合蛋白（PBP）结合并使之失活。
S4865	Cefetamet pivoxil hydrochloride Cefetamet pivoxil hydrochloride is the hydrochloride salt form of cefetamet pivoxil, which is an oral third-generation cephalosporin antibiotic.
S5359	Butoconazole Ethyl chrysanthemate is an allelochemical compound used as an attractant.	Nature, 2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S5941	Besifloxacin Besifloxacin是第四代氟喹诺酮类眼部抗生素，用于治疗细菌性结膜炎。
S4866	Nicarbazin Nicarbazin是一种有效的抗球虫试剂，是一种广谱的寄生虫药物。
S5366	Fipronil Fipronil is a recalcitrant phenylpyrazole-based pesticide used for flea/tick treatment and termite control that is distributed in urban aquatic environments via stormwater and contributes to stream toxicity.
S9094	Pogostone Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
S4420	Mefloquine HCl Mefloquine HCl是一种血液裂殖体杀灭剂，抑制疟原虫色素的形成，用作抗疟疾药物。	Int J Parasitol Drugs Drug Resist, 2018, 8(2):331-340 PLoS Negl Trop Dis, 2017, 11(9):e0005942	BALB/c mice, orally infected with E. multilocularis eggs, were treated by either mefloquine (100 mg/kg twice per week, n = 9), ABZ (200 mg/kg, 5 times per week, n = 8) or control-treated (placebo, n = 9). After 12 weeks of treatment, parasite lesion numbers in the liver were assessed microscopically (A).
S3966	Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S4880	Cefathiamidine Cefathiamidine is the first generation of cephalosporin antibacterial used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis.
S5531	Doripenem Doripenem is a new parenteral carbapenem antibiotic with broad-spectrum activity against gram-negative and gram-positive pathogens.
S9158	Atractylon Atractylon, the sesquiterpenoid oxide isolated from the rhizomes of Atractylodes japonica and its related plants (Compositae), shows significant antiviral activities for influenza A virus.
S3971	Fusidine Fusidine, isolated from Fusidium coccineum, is a steroidal antibiotic that inhibits protein synthesis.
S1617	Sulfapyridine Sulfapyridine 是一种磺胺类抗菌药。
S5332	Cefquinome sulfate Cefquinome sulphate is a veterinary, parenteral, and fourth-generation cephalosporin. Its antimicrobial potency and extensive antibacterial spectrum result from the introduction of a methoxyimino-aminothiazolyl moiety into the acyl side chain.
S5278	Tedizolid (TR-700) Tedizolid is an oxazolidinone-class antibiotic prodrug used for the treatment of acute bacterial skin and skin structure infections caused by susceptible isolates of several Gram-positive bacteria.
S4029	Colistin Sulfate Colistin是一种环状阳离子十肽，链接到脂肪酸侧链，属于一组结构类似的细菌抗微生物肽。	Biogerontology, 2016, 17(5-6):907-920
S4122	Tilmicosin Tilmicosin 是一种大环内酯类抗菌素。
S2052	Oxytetracycline Dihydrate Oxytetracycline Dihydrate 是一种处方抗生素，干扰细菌产生必需蛋白质的能力。
S5532	Erythromycin estolate Erythromycin, a naturally occurring macrolide, is derived from Streptomyces erythrus. It inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5535	Moxifloxacin Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.	Transl Vis Sci Technol, 2018, 7(2):11 Circ Arrhythm Electrophysiol, 2016, 9(4):e003655 Invest Ophthalmol Vis Sci, 2015, 56(4):2234-42
S5684	Lapachol Lapachol, a natural compound isolated from the bark of the lapacho tree, shows both antimicrobial and antiviral activity.
S4876	Robenidine Hydrochoride Robenidine hydrochloride是一种应用于家禽中的抗球虫剂。
S5625	Ammonium lactate Ammonium lactate is the ammonium salt of lactic acid with mild anti-bacterial properties.
S4869	Sulfamethoxazole sodium Sulfamethoxazole sodium是一种用于治疗细菌感染的抗生素。
S5719	Ceftizoxime sodium Ceftizoxime sodium is a semisynthetic cephalosporin antibiotic that is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
S2058	Tolnaftate Tolnaftate 是一种合成的硫代氨基甲酸酯，用作抗真菌剂。
S5054	Rifamycin sodium salt Rifamycin sodium is an antibacterial drug used for treatment of mycobacterium infections.
S4584	Butylparaben Butylparaben是一种常在化妆品中被用作抗菌防腐剂的化合物。	Environ Toxicol, 2018, 33(4):436-445
S5207	Cephalexin Monohydrate Cephalexin is a semisynthetic cephalosporin antibiotic with antimicrobial activity.
S4585	Succinylsulfathiazole Succinylsulfathiazole是一种磺胺类抗生素。
S5491	Lomefloxacin Lomefloxacin is a fluoroquinolone antibiotic used to treat bacterial infections.
S4142	Clopidol Clopidol是一种抗原虫药剂。
S4592	Captisol (SBE-β-CD) SBE-β-CD是一种新型的、化学修饰过的环糊精，具有比较好的稳定性和溶解性。	Theranostics, 2019, 9(3):796-810 J Exp Clin Cancer Res, 2019, 38(1):264 Cell Death Dis, 2017, 8(5):e2776
S5331	Ceftezole sodium Ceftezole Sodium is the sodium salt form of ceftezole, a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4595	Cefazolin Sodium Cefazolin Sodium 是一种半合成的头孢菌素类似物，具有广谱抗菌作用，抑制细菌细胞壁的合成。它能达到较高的血清水平，通过尿液排泄出去。
S5333	Sulbenicillin Sodium Sulbenicillin Sodium is the sodium salt of sulbenicillin, which is a penicillin antibiotic.
S5936	Cefazolin Cefazolin是一种半合成的头孢菌素，具有广谱的抗菌作用，抑制细菌细胞壁的合成。它可达到高血清水平，通过尿液快速排泄。
S4145	Decoquinate Decoquinate是一种球虫抑制药。
S4596	Cefixime Cefixime是一种对于治疗许多细菌感染疾病有用的抗生素。
S5700	Phthalylsulfathiazole Phthalylsulfathiazole is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
S6118	Terpinen-4-ol Terpinen-4-ol是一种天然存在的单萜，是茶树油的主要活性成分，具有多种生物活性如抗真菌活性。
S4148	Ampicillin Trihydrate Ampicillin Trihydrate是β-内酰胺类抗生素，通过使细菌细胞膜内表面上的转肽酶失活而抑制细菌细胞壁合成（肽聚糖的交联）。
S4996	Tavaborole (AN-2690) Tavaborole (AN-2690) is a boron-containing small molecule with broad spectrum antifungal activity.
S2259	Aloe-emodin Aloe-emodin是一种干扰素诱导剂，作用于JEV，IC50为1 μg/mL，作用于EV71，IC50为0.33 μg/mL。	J Tradit Complement Med, 2015, 5(2):96-9	Flow cytometry result. Promastigotes were stained with Annexin V and propidium iodide 48 hours after treatment with aloe-emodin
S4041	Olsalazine Sodium Olsalazine Sodium 是一种抗炎症前体药，包含2个5-ASA部分，通过偶氮键相连。	Oncotarget, 2017, 8(1):228-237	Values represent the average scores for each group ± S.E. (N = 10 per group). The differences between individual experimental groups and 17 days DSS only group were statistically significant (p < 0.05) for all groups.
S4150	Orbifloxacin Orbifloxacin是一种人工合成的广谱fluoroquinolone抗生素。
S4620	Cefuroxime sodium Cefuroxime Sodium是一种对携有β-内酰胺酶抗性的gram-positive和gram-negative细菌具有有效抑制作用的头孢菌素。
S4875	Cephapirin Benzathine Cephapirin Benzathine是cephapirin的苄星青霉素盐形式。Cephapirin是半合成的、广谱的、第一代头孢菌素，具有抗菌活性。
S6136	(±)-α-Bisabolol α-bisabolol是一种植物来源的油性倍半萜烯醇，具有抗炎和抗菌活性。
S4885	Taurolidine Taurolidine是一种合成的、广谱的抗生素，具有抗细菌、抗凝的和潜在的抗血管新生的活性。
S5757	Isoeugenol Isoeugenol, an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
S4250	Sulfamethoxypyridazine Sulfamethoxypyridazine是长效磺胺类药物，用于治疗疱疹样皮炎。
S9278	Saikosaponin C Saikosaponin C is a triterpene saponin found in Bupleurum that exhibits antiviral and pro-angiogenic activities.
S5397	Chlorhexidine Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.
S4156	Chlortetracycline HCl Chlortetracycline HCl是首批确定的四环素类抗生素。
S4158	Ceftriaxone disodium salt hemi(heptahydrate) Ceftriaxone disodium salt hemi(heptahydrate)是第三代头孢菌素类抗生素。
S6173	Amylmetacresol Amylmetacresol是一种防腐杀菌剂，用于治疗口腔和喉咙的感染。
S6185	Arachidonic acid Arachidonic acid是非饱和必需脂肪酸，在动物和人类肝脏、脑部和腺器官脂肪中都有发现。它是前列腺素、凝血噁烷和白细胞三烯的生物合成的前体化合物。
S4160	Penicillin G Sodium Benzylpenicillin sodium 是由Penicillin spp产生的β-内酰胺类抗生素。
S2271	Berberine chloride Berberine chloride是异喹啉类生物碱的季铵盐。	Oncol Rep, 2018, 40(3):1525-1532 Shandong University, 2014, Haoran Cui
S4942	4-Hydroxy-3,5-dimethoxybenzyl alcohol 4-Hydroxy-3,5-dimethoxybenzyl alcohol，也被称作Syringic alcohol，是一种酚类，具有抗病毒活性。
S5492	Econazole Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.
S4874	Cefazedone Cefazedone是一种半合成的一代头孢菌素，具有抗细菌活性。
S2282	Cinchonidine Cinchonidine是一种生物碱，在有机化学中用于不对称合成。
S5475	Novaluron Novaluron belongs to the class of insecticides called insect growth regulators with pesticide properties.
S9292	Dictamnine Dictamnine, a natural plant product, has been reported to have antimicrobial activity against bacteria and fungi.
S5296	Cephradine monohydrate Cefradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
S5290	Ormetoprim Ormetoprim (OMP) is an antibiotic to prevent the spread of disease in freshwater aquaculture.
S5487	Cefoperazone sodium Cefoperazone Sodium is the sodium salt form of cefoperazone, which is a semi-synthetic, broad-spectrum, beta-lactamase resistant antibiotic with bactericidal activity.
S4610	Mebendazole Mebendazole是一种合成的苯并咪唑衍生物，还是一种驱虫药物。它能通过抑制寄生虫的胞质微管的形成，干扰它们的生殖和生存，有选择性的、不可逆的抑制糖吸收。	J Biol Chem, 2019, 10.1074/jbc.RA119.010144
S4822	Silver Sulfadiazine Silver sulfadiazine是一种杀菌剂，对很多革兰氏阴性和阳性的细菌以及酵母都十分有效。
S5294	Cephalotin acid Cephalotin acid is a cephalosporin antibiotic.
S5736	Benzathine penicilline Benzathine penicilline is an antibiotic useful for the treatment of a number of bacterial infections.
S4167	Cyromazine Cyromazine是一种三嗪类昆虫生长调节剂，作为杀虫剂和杀螨剂。
S4612	Dapson Dapsone是一种抗生素，常与利福平及氯法齐明结合使用，用于治疗麻疯病。
S1884	Sparfloxacin Sparfloxacin 是一种喹诺酮类抗生素，具有广谱有效的抗菌活性。
S5722	Oxantel Pamoate Oxantel Pamoate is the pamoate salt form of oxantel, a tetrahydropyrimidine anthelmintic used against intesitnal worms, particularly in a veterinary setting.
S1395	Polymyxin B sulphate Polymyxin B是一种抗生素，用于抵抗革兰阴性菌感染。	Free Radic Biol Med, 2019, 137:24-36
S2385	Hordenine Hordenine是一种苯乙胺生物碱具有抗菌特性。
S4634	Sodium sulfadiazine Sodium Sulfadiazine是sulfadiazine的钠盐形式，一种具有中效抑菌作用的合成sulfanilamide衍生物。
S4959	Skatole Skatole (3-Methylindole)是一种具有轻度毒性的白色结晶有机化合物，天然存在于排泄物中，具有相当广泛的抑菌作用。
S5601	Balofloxacin Dihydrate Balofloxacin Dihydrate is an orally active fluoroquinolone antibiotic.
S4172	Cetylpyridinium Chloride Cetylpyridinium chloride是一种阳离子季铵化合物，作为口咽消毒剂。
S4641	Tedizolid Phosphate Tedizolid是一种恶唑烷酮类的抗生素。Tedizolid phosphate是活性化合物tedizolid的磷酯前体药物。	Sci Transl Med, 2019, 11(516)
S6243	Ethyl pyruvate Ethyl pyruvate是丙酮酸一种简单的脂肪族酯，通过发挥消炎、抗氧化和抗凋亡活性而具有神经保护作用。
S3695	Cystamine dihydrochloride Cystamine dihydrochloride acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes.
S5291	sulfaisodimidine Sulfisomidin is a sulfonamide antibacterial.
S4175	Sulfaguanidine Sulfaguanidine是一种磺胺药物，作为抗感染剂。
S2395	Rheochrysidin Rheochrysidin 是大承气汤的主要成分之一，用于治疗炎症。	ACS Chem Biol, 2015, 10.1021/cb5009487	AmpC β-lactamase and MDH inhibition dose-response curves in the absence (black circles) and presence (red triangles) of DTT for (C and D) physcion.
S3787	Picroside I Picroside I, an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S3645	Kitasamycin Kitasamycin is a macrolide antibiotic. It has antimicrobial activity against a wide spectrum of pathogens.
S4178	Climbazole Climbazole是一种广谱的咪唑类抗真菌药剂，具有抗头皮屑的效果。
S3644	Sulfamonomethoxine
S9016	Dipsacoside B Dipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity.
S3646	Thimerosal Thimerosal is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks.
S5298	Amoxicillin trihydrate Amoxicillin is a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity.
S5546	Sulfacetamide Sulfacetamide is a synthetic sulfanylacetamide derivative with bacteriostatic activity. It is an anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
S5908	Garenoxacin Garenoxacin (T-3811ME, BMS-284756)是一种新型的des-F(6)喹诺酮，在体外对许多病原体具有有效作用，包括gram-positive和gram-negative的需氧菌和厌氧菌。
S4179	Mezlocillin Sodium Mezlocillin Sodium是青霉素的beta-内酰胺类抗生素，通常用于治疗革兰氏阳性菌引起的感染。
S4060	Erythromycin Ethylsuccinate Erythromycin Ethylsuccinate, 是一种口服的大环内酯类抗菌素，由链霉菌产生, 可以可逆的结合细菌50S 核糖体并抑制蛋白合成。
S5515	Penicillin G Procaine Procaine benzylpenicillin, also known as Procaine benzylpenicillin, is an antibiotic useful for the treatment of a number of bacterial infections.
S3649	Ceftazidime Ceftazidime is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
S5289	Ceftezole Ceftezole is a semi-synthetic first-generation cephalosporin with antibacterial activity.
S4062	Ronidazole Ronidazole 是一种抗原生动物药剂。
S4183	Paromomycin Sulfate Paromomycin Sulfate是氨基糖甙类抗生素，作用于非抗性细胞，通过与16S核糖体RNA结合，从而抑制蛋白合成。
S3655	Cefepime Dihydrochloride Monohydrate Cefepime is a cephalosporin antibacterial drug used to treat pneumonia, urinary tract, skin, and intra-abdominal infections.
S5020	Tilorone dihydrochloride Tilorone dihydrochloride是一种广谱的、具有口服活性的抗病毒试剂，可激活干扰素的生成。它具有抗肿瘤和抗炎活性。
S5637	Cefotiam Hexetil Hydrochloride Cefotiam Hexetil Hydrochloride is the hydrochloride salt of cefotiam hexetil. Cefotiam is a semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.
S4541	Triclosan Triclosan是在化妆品和香皂中被用作防腐剂的二苯醚衍生物。它具有抑菌作用。	FASEB J, 2019, 10.1096/fj.201802603RR Onco Targets Ther, 2018, 11:2945-2954
S4971	Buparvaquone Buparvaquone是第二代羟基萘醌化合物，有希望治疗和预防泰勒虫病。
S5638	Cefozopran hydrochloride Cefozopran Hydrochloride is the hydrochloride salt form of cefozopran, a semi-synthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity.
S4187	Salicylanilide Salicylanilides是一组具有广泛的生物活性的化合物，具有抗病毒效力，抗菌（包括抗分枝杆菌），和抗真菌活性。
S5299	Tosufloxacin p-Toluenesulfonate Hydrate Tosufloxacin is a fluoroquinolone antibiotic that is used to treat susceptible infections.
S5644	Ceftriaxone Sodium Ceftriaxone Sodium is the sodium salt form of ceftriaxone, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.
S4720	Cefotaxime Cefotaxime是第三代头孢菌素抗生素，对革兰氏阴性菌和阳性菌具有广谱活性。
S4898	Sulfalozine sodium Sulfalozine sodium是一种抗原生动物药，用于球虫病的研究。
S5295	Lincomycin Hydrochloride Monohydrate Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.
S4068	Tinidazole Tinidazole是抗寄生药。
S3676	Carbendazim Carbendazim is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S2315	Kanamycin sulfate Kanamycin sulfate(Kanamycin monosulfate)是一种氨基糖苷类化合物，口服有效，可静脉注射，肌肉注射，广泛应用于感染。
S4192	Chlorquinaldol Chlorquinaldol是一种抗微生物药剂。
S4258	Luliconazole Luliconazole是一种广谱抗真菌药物。
S5420	Clindamycin alcoholate Clindamycin alcoholate is a crystallizable compound of Clindamycin with alcohol. Clindamycin is a semisynthetic lincosamide antibiotic that inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits.
S5816	pyrvinium Pyrvinium是一种驱虫剂，对蛲虫有效。
S4882	Resorantel Resorantel是一种安全的抗绦虫药，对莫尼茨绦虫和Thysaniezia spp.十分有效，对Paramphistomum spp.有一定效力。
S5421	Fluoroquinolonic Acid Fluoroquinolonic Acid is an antibiotic and antimicrobial agent.
S5292	Diazolidinyl urea Diazolidinyl urea is an antimicrobial preservative used in cosmetics.
S4750	Sulfacetamide sodium salt hydrate Sulfacetamide是一种磺胺类抗生素，通过抑制dihydropteroate synthase(DHPS)阻滞二氢叶酸的合成。Sulfacetamide是细菌para-aminobenzoic acid (PABA)的竞争性抑制剂，PABA是细菌合成叶酸所必需的。
S5017	Oxyclozanide Oxyclozanide是N-水杨酰苯胺驱虫剂，也是线粒体解偶联驱虫剂。兽用。
S9046	Berberine Berberine, an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.	J Biol Chem, 2018, 293(29):11341-11357
S4870	Cefodizime Sodium Cefodizime Sodium是第三代头孢菌素类抗生素，具有广谱活性，对多数beta-lactamases稳定。
S9057	Sinigrin Sinigrin is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.	J Invest Dermatol, 2018, 138(12):2644-2652
S5887	Khellin Khellin分离自阿密茴（伞形科）种子，被用于治疗多种疾病。
S4081	Sulfacetamide Sodium Sulfacetamide Sodium是一种抗生素。
S3636	Cefadroxil hydrate Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.
S3637	Cefpirome sulfate Cefpirome is a fourth-generation cephalosporin and is considered highly active against Gram-negative bacteria.
S4759	p-Coumaric Acid p-Coumaric acid是肉桂酸的羟基衍生物。肉桂酸存在于多种可食用植物，具有抗氧化、消炎和抗菌活性。	J Nutr Biochem, 2015, 26(11):1379-84
S3638	Cefamandole nafate Cefamandole Nafate is the sodium salt form of cefamandole formyl ester. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
S5440	Berberine Sulfate Berberine sulfate, an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria, fungi, and protozoa.
S5948	Amodiaquine Amodiaquine是一种合成的氨基喹啉，通过与原生动物或寄生DNA结合、阻止DNA和RNA的生成以及后续蛋白质的合成。它被用于治疗疟疾。
S5016	Isoprinosine Isoprinosine是一种免疫药理试剂，具有抗病毒活性。
S2534	Isoconazole nitrate Isoconazole nitrate 是一种唑类抗真菌药物。
S4978	Azathramycin Azathramycin (Azaerythromycin)是一种含红霉支糖的大环内酯抗生素。
S3713	Moxidectin
S7411	Ascomycin (FK520) Ascomycin (FK520), FK-506的一种类似物, 是中性的大环内酯类 immunosuppressant, 能够防止器官移植后的排斥反应。
S5784	Vancomycin Vancomycin是一种抗生素，用于治疗各种细菌感染。
S3705	Chlorobutanol Chlorobutanol (trichloro-2-methyl-2-propanol)是一种防腐剂、镇静剂、催眠剂和弱的局部麻醉剂，具有抗菌抑菌作用。
S3860	Allicin Allicin, the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9387	Maackiain Maackiain is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
S3707	Ethopabate Ethopabate (ETP)是一种球虫抑制剂，常被用于治疗鸡类球虫病。
S3708	Sulfachloropyridazine Sulfachloropyridazine是一种抗生素，用于治疗多种细菌感染。
S4201	Florfenicol Florfenicol是一种氟化的Thiamphenicol合成类似物，具有广谱的抑菌活性。
S4663	Fusidate Sodium Fusidate Sodium是fusidic acid的钠盐形式，fusidic acid是一种来自于梭链孢菌的抑菌性抗生素，被用来作为局部药物治疗，治疗皮肤感染。
S3709	Furagin Furagin是一种2-substituted 5-nitrofuran，在化学结构上与已知的抗细菌化合物nitrofurantoin类似，具有抑菌活性。
S5041	Difloxacin hydrochloride Difloxacin是第二代合成的氟喹诺酮抗菌抗生素，兽用。
S4203	Furaltadone HCl Furaltadone HCl是一种抗菌药，治疗球虫病具有明显的疗效。	Eur J Pharmacol, 2018, 828:119-125
S5657	Ertapenem sodium Ertapenem Sodium is the sodium salt of ertapenem, a long-acting, broad-spectrum antibiotic of β-lactam subclass.
S9078	Epigoitrin Epigoitrin, the main bioactive constituent of Radix isatidis, exerts antiviral, anticancer, and antithyroid activities.
S4986	Latamoxef sodium Latamoxef sodium is an antibiotic and has anti-bacterial and anti-inflammation effects.
S5033	Terconazole Terconazole是一种新型的、广谱的、三唑抗真菌试剂，主要用于治疗阴道真菌感染。
S9084	Rhoifolin Rhoifolin, a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
S3058	Danofloxacin Mesylate Danofloxacin Mesylate是一种喹诺酮类抗菌剂，兽医用药，MIC90为0.28 μM。
S4271	Isepamicin Sulphate Isepamicin Sulphate是一种氨基糖苷类antibiotic，以细菌30S核糖体亚基为靶点抑制细菌蛋白质的合成。
S3672	Cefonicid sodium Cefonicid sodium is a cephalosporin antibiotic. It interferes with cell wall biosynthesis in bacteria, leading to lysis of the infectious organism.
S4213	Dirithromycin Dirithromycin是大环内酯类糖肽抗生素，通过与细菌70S核糖体的50S亚基结合，从而抑制肽易位。
S4215	Ribostamycin Sulfate Ribostamycin是一种氨基糖苷类抗生素，含有中性糖配基，由核糖苷链霉素产生。	Pathogens, 2019, 8(3)
S4216	Valnemulin HCl Valnemulin是天然存在的二萜类抗生素pleuromutilin的半合成衍生物，它的作用是抑制肽基转移酶。
S5055	Milbemycin Oxime Milbemycin Oxime是广谱性抗寄生虫药物，对蠕虫和螨虫具有活性作用。
S4671	Cefradine Cephradine是一种半合成的头孢菌素抗生素。
S5070	Mupirocin calcium Mupirocin Calcium是mupirocin的钙盐形式。Mupirocin是一种天然的巴豆酸衍生物，提取自荧光假单胞菌，抑制细菌蛋白质合成，被用作一种抗生素。
S6067	2,4-dichlorobenzyl alcohol 2,4-Dichlorobenzyl alcohol是一种温和的防腐剂，能够杀死口喉感染相关的细菌和病毒。
S6068	Doxycycline monohydrate Doxycycline是一种合成的、广谱的四环素类抗生素，具有抗菌活性。
S5724	Dichlorophene Dichlorophen is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829	Monomyristin Monomyristin具有抗细菌和抗真菌活性。
S2334	Oleanolic Acid Oleanolic Acid是一种天然存在的三萜类，广泛分布于食用和药用植物，与桦木酸相关，具有相对无毒的，抗肿瘤，保肝，及抗病毒的特性。	J Asian Nat Prod Res, 2018, 10.1080/10286020.2018.1461087
S9099	Orientin Orientin, isolated from medicinal plants, has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects.
S3801	Sodium Houttuyfonate Sodium Houttuyfonate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
S5776	Proflavine Proflavine是一种消毒抑菌剂，可抑制许多革兰氏阳性菌。它常被用作伤口敷料中的局部杀菌剂。
S4222	Piperacillin Sodium Piperacillin 是一种半合成的，广谱氨苄青霉素衍生的Ureidopenicillin抗生素，用于治疗假单胞菌感染。	Analytical Methods, 2018, 10.1039/C8AY00150B
S4601	Clioquinol Clioquinol是一种具有口服活性的、亲油性的、铜离子结合的卤代8-羟基喹啉（8-hydroxyquinoline），具有抗真菌、抗寄生物以及潜在的抗肿瘤活性。	FASEB J, 2019, 10.1096/fj.201802603RR
S3650	Penicillin V potassium salt Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan.
S5031	Sulfaquinoxaline sodium Sulfaquinoxaline sodium (N'1-quinoxalin-2-ylsulphanilamide sodium, SQ-Na)是sulfaquinoxaline的钠盐形式，通过抑制微生物的核酸、蛋白的合成，用于治疗家禽、猪、羊的球虫病。
S2613	Clorsulon Clorsulon用于治疗小牛和羊的肝片吸虫感染。
S9328	5,6,7-Trimethoxyflavone 5,6,7-Trimethoxyflavone, methylations of the hydroxyl groups of oroxylin A or baicalein, has various pharmacological activities including antiviral, anticancer and antibacterial.
S4111	Dicloxacillin Sodium Dicloxacillin Sodium是一种β-内酰胺酶抑制剂，类似苯唑青霉素，它对革兰氏阳性菌以及革兰氏阴性好氧细菌和厌氧菌都具有活性。
S5065	Ganciclovir sodium Ganciclovir Sodium is the sodium salt form of ganciclovir, a synthetic, antiviral, purine nucleoside analog with antiviral activity, especially against cytomegalovirus (CMV).
S5036	Nisin Nisin是一种核糖体合成的肽段，具有广谱的抑菌活性，抑制多种细菌包括食品腐败菌与致病菌。
S3722	Isavuconazole Isavuconazole是新型超广谱三唑类化合物，对酵母、霉菌和双态性真菌具有活性，抑制cytochrome P450 (CYP)依赖性的14α-lanosterol脱甲基作用，以此抑制真菌细胞膜麦角固醇的合成。
S5541	Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S9342	1,4-Naphthoquinone 1,4-Naphthoquinone, found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide.
S2564	Cloxacillin Sodium Cloxacillin Sodium是Cloxacillin的钠盐形式，是一种耐青霉素酶，耐酸，半合成的青霉素。
S3121	Ornidazole Ornidazole 是5-硝基咪唑衍生物，具有抗原虫和抗厌氧菌的抗菌性能。
S3979	Zinc Undecylenate Zinc Undecylenate is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S9112	Kaempferitrin Kaempferitrin, isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S5096	SulfadiMethoxine sodium Sulfadimethoxine是一种长效的磺胺类抗菌剂，用于治疗多种感染，如呼吸道、尿道、肠道和软组织感染。	Cell Death Dis, 2018, 9(6):646
S9113	Ononin Ononin is an isoflavone glycoside with anti-inflammtory effects.
S5924	Olanexidine Hydrochloride semihydrate Olanexidine是一种具有杀菌活性的单双胍化合物。
S4232	Nithiamide Nithiamide 是一种非5-硝基咪唑类药物。
S3618	Acetylspiramycin (ASPM) Acetylspiramycin (ASPM)是大环内酯物抗菌剂。
S5086	p-Anisaldehyde p-Anisaldehyde (4-methoxybenzaldehyde)，茴芹种子提取物，具有抗真菌活性，对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。
S9120	Scutellarein Scutellarein, extracted from the perennial herb Scutellaria lateriflora, has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities.
S5410	Chloramphenicol sodium succinate Chloramphenicol Sodium Succinate is the sodium succinate salt form of chloramphenicol, a nitrobenzene derivate and broad-spectrum antibiotic with antibacterial activity.
S4517	Cefotaxime sodium Cefotaxime sodium salt是第三代头孢菌素抗生素，是一种广谱的、具有抵抗大多数Gram-positive和Gram-negative细菌的抗菌剂。
S9122	Tectorigenin
S4518	Chloroxylenol Chloroxylenol是一种广谱的抗菌类化合物，用来抵抗细菌、藻类、真菌和病毒。
S5209	Enoxacin Sesquihydrate Enoxacin sesquihydrate是一种广谱的6-fluoronaphthyridinone抗菌剂。
S9377	Eugenyl acetate Eugenyl acetate, an aromatic component of clove essential oil, exhibits various pharmacological activities, including antibacterial and anti-virulence activities against drug-resistant A. baumannii clinical isolates.
S3132	Sulfamerazine Sulfamerazine是磺胺类抗菌药。
S4236	Proflavine Hemisulfate Proflavine Hemisulfate是一种外用防腐剂，通过与DNA螯合从而破坏DNA合成，且导致复制的DNA链发生高水平的突变。
S5208	Ciprofloxacin hydrochloride hydrate Ciprofloxacin Hydrochloride是ciprofloxacin的盐酸盐形式，ciprofloxacin是一种抗生素，用于治疗一些细菌感染疾病。
S5573	Tilmicosin phosphate Tilmicosin phosphate is a macrolide antibiotic that is used to treat cattle for pathogens that cause Bovine Respiratory Disease.
S3065	Amikacin disulfate Amikacin sulfate是一种半合成，水溶性的卡那霉素氨基糖苷类衍生物，可以结合到细菌30S 核糖体亚基上引起mRNA读取错误从而导致细菌不能合成自身生长所必需的蛋白。
S4523	Dihydrostreptomycin sulfate Dihydrostreptomycin sulfate是氨基糖苷类抗生素，用来在牛、猪和羊中治疗细菌性疾病。Dihydrostreptomycin是链霉素的衍生物。
S3746	Lumefantrine Lumefantrine是一种抗疟疾剂，用于治疗急性无并发症的疟疾。
S5212	Imidazolidinyl Urea Imidazolidinyl Urea是一种抗菌剂，在化妆品中被用作防腐剂。
S5473	Pivmecillinam hydrochloride
S9444	Tomatine Tomatine is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525	Ethylparaben Ethylparaben是对羟基苯甲酸（p-hydroxybenzoic acid）的乙酯形式，被用作抗真菌防腐剂和食品添加剂。它还是一种化学过敏原，其生理效应是通过增加组胺释放和细胞所介导的免疫反应所实现。
S5210	Sulfamethazine Sodium Salt Sulfamethazine是磺胺类抗感染试剂，用于畜牧业。
S5202	Quinocetone Quinocetone是一种新型的兽用化合物，具有杀菌作用和潜在的抗肿瘤活性。
S4528	Furazolidone Furazolidone是一种合成的硝基呋喃衍生物。对Gram-positive和Gram-negative的细菌具有灭菌或抑菌作用。
S4678	Povidone iodine Povidone iodine（聚维酮碘）是聚乙烯吡咯烷酮（PVP）和碘元素的稳定化合复合体。在外科手术中被用作是局部消毒剂，防止皮肤及黏膜感染。
S5201	Acetylisovaleryltylosin Tartrate Acetylisovaleryltylosin tartrate是一种具有抗菌作用的大环内酯物，对革兰氏阳性细菌具有抑制活性。
S5206	Benzylpenicillin potassium Benzylpenicillin potassium是青霉素G的钾盐形式，青霉素G是广谱的青霉素抗生素。
S5211	4-Aminosalicylic acid 4-Aminosalicylic acid (Aminosalicylic acid)是一种抗结核药，对结核杆菌具有抑菌活性。
S5094	Maduramycin Ammonium Maduramicin，可分离来源于放射菌类Actinomadura rubra，是一种抗原虫剂，用于阻止球虫病，兽用。	Cancers (Basel), 2019, 11(6)
S4833	Cefoxitin sodium Cefoxitin Sodium is the sodium salt form of cefoxitin, a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.
S4536	Nitrofurantoin Nitrofurantoin是一种用来治疗膀胱感染的抗菌素。抑制细菌DNA、RNA和细胞壁蛋白合成。
S9135	Artemisic acid Artemisic acid (Artemisinic acid), an amorphane sesquiterpene isolated from Artemisia annua L., has a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect.
S5093	Rafoxanide Rafoxanide是一类N-水杨酰苯胺，被用作驱虫剂，在治疗和控制动物体内吸虫感染中有效。
S9136	Neochlorogenic acid Neochlorogenic acid is a natural polyphenolic compound found in some types of dried fruits and a variety of other plant sources such as peaches. It shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia.
S3170	Ampicillin sodium 作为青霉素家族的一种β-内酰胺类抗生素，Ampicillin sodium能够渗透入革兰氏阳性菌和某些革兰氏阴性菌。Ampicillin是转肽酶的一种竞争性抑制剂，而转肽酶是细菌形成细胞壁所必需的。Ampicillin 能够抑制细胞细胞壁形成过程中的第三步和最后一步从而最终导致细胞裂解。	Vet J, 2018, 234:24-26
S5092	Febantel Febantel是一种前体药物，可代谢成为fenbendazole和oxfendazole，它们是活性驱虫剂。
S5350	Cefpodoxime proxetil Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.
S5557	Aklomide Aklomide is a coccidiostat and used to fight disease, parasites and insects that infest poultry.
S4540	Sisomicin sulfate Sisomicin sulfate是一种从小单孢菌属的新物种的发酵液中分离出来的氨基糖苷抗生素。
S4878	Neticonazole Hydrochloride Neticonazole是咪唑类抗真菌剂，用于治疗皮肤真菌感染。
S4242	Cetrimonium Bromide (CTAB) Cetrimonium Bromide是广谱防腐剂西曲溴铵的一种已知组分，西曲溴铵是不同季铵盐的混合物。	Micromachines (Basel), 2018, 9(6)
S5095	Olaquindox Olaquindox是一种口服的抗细菌剂，被用作动物食品中的添加剂。
S5214	Imidocarb dipropionate Imidocarb是一种抗原虫剂，在治疗巴贝西虫病和埃里希体病中被用作二丙酸盐使用。	Nat Commun, 2017, 8(1):823
S3978	5-Phenyl-2,4-pentadienoic acid 5-Phenyl-2,4-pentadienoic acid is used as Synthetic building block, anti-malarial agent.
S5159	Doxycycline Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa.	Life Sci, 2020, 243:117234 Int J Oncol, 2017, 50(5):1792-1800 Int J Hematol, 2016, 103(1):95-106
S4279	Demeclocycline HCl Demeclocycline HCl 是一种四环素antibiotic可抑制细菌的蛋白合成，用于治疗细菌感染。	Sci Rep, 2018, 8(1):7653
S5390	N-(Hytroxymethy)micotinamide N-(Hydroxymethyl)nicotinamide is an antimicrobial agent.
S5744	Spiramycin I Spiramycin I is a main component of spiramycin, which is a macrolide antimicrobial agent with broad spectrum antibiotic activity.
S4813	Cefuroxime axetil Cefuroxime axetil, a prodrug of the cephalosporin cefuroxime, is a second generation oral cephalosporin antibiotic with in vitro antibacterial activity against several gram-positive and gram-negative organisms.
S5373	Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
S4547	8-Hydroxyquinoline 8-Hydroxyquinoline是一种具有轻度抑制真菌、细菌、驱虫、杀伤阿米巴原虫特性的防腐剂。也被用作金属螯合剂、放射性铟的载体用于诊断治疗。
S5354	Cefteram pivoxil Cefteram Pivoxil is the pivalate ester prodrug of cefteram, a semi-synthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity.
S4843	Potassium acetate Potassium acetate is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S4550	Azelaic acid Azelaic acid（壬二酸）是一种通过油酸臭氧分解而来的有机化合物，具有抗菌、消除粉刺、抗氧化活性。
S4844	Cefcapene Pivoxil Hydrochloride Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene, a semi-synthetic third-generation cephalosporin with antibacterial activity.
S5355	Piperaquine phosphate Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
S5351	Cefmetazole sodium Cefmetazole sodium is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
S9560	Anisodamine Hydrobromide Anisodamine是天然存在的阿托品（atropine）衍生物，具有消炎活性。它能抑制α1-adrenergic receptors和mAChRs。
S3910	4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S5009	Brivudine Brivudine is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. It is incorporated into the viral DNA and blocks the action of DNA polymerases, thus inhibiting viral replication.
S4287	Micafungin Sodium Micafungin Sodium是1,3-β-D-葡聚糖合成抑制剂，用作抗真菌的药物。	Antiviral Res, 2018, 159:134-142 Cell Physiol Biochem, 2016, 584-95 Virol J, 2016, 13(1):99	Effect of Micafungin on erythrocyte forward scatter. A. Original histogram of forward scatter of erythrocytes following exposure for 48 hours to Ringer solution without (grey area) and with (black line) presense of 25 µg/ml Micafungin. B. Arithmetic means ± SEM (n = 14) of the erythrocyte forward scatter (FSC) following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). C. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter(FSC) <200 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). D. Arithmetic means ± SEM (n = 14) of the percentage of erythrocytes with forward scatter (FSC) >800 following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Micafungin (10-25 µg/ml). ***(p<0.001) indicates significant difference from the absence of Micafungin (ANOVA).
S5005	Cefotiam hydrochloride Cefotiam hydrochloride is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
S4553	Bronopol Bronopol(2-bromo-2-nitropropane-1,3-diol)是一种抗细菌剂，在化妆品行业被用作防腐剂。
S5859	Sancycline Sancycline是一种半合成四环素抗生素。
S1962	Sulphadimethoxine Sulphadimethoxine 是一种非还原性的葡糖苷酸。
S5007	Delamanid Delamanid是一种新型的抗肺结核药物，具有良好的胞内杀菌活性，在细胞中具有高积累率。
S4555	Carsalam Carsalam是一种非类固醇的消炎药。
S4812	Ceftizoxime Ceftizoxime is a semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.
S5863	Metronidazole Benzoate Metronidazole Benzoate是metronidazole的苯甲酸酯形式。Metronidazole是一种合成的硝基咪唑衍生物，具有抗原生动物和抗细菌活性。
S4559	Cloxiquine Cloxiquine是一种抗细菌、抗真菌、抗衰老和抗痨药物。
S7896	Sodium Tauroursodeoxycholate (TUDC) Sodium Tauroursodeoxycholate (TUDC)是一种水溶性胆汁酸，用于治疗胆结石和肝硬化。	Int J Biol Sci, 2019, 15(9):1905-1920
S4521	DEET DEET是一种常见的杀虫剂的活性成分。
S4522	Dehydroacetic acid Dehydroacetic acid是一种有机化合物，主要用作杀菌剂。
S5108	Tylosin Tylosin is a macrolide-class broad spectrum antibiotic that's used in veterinary medicine to treat felines, canines and livestock.
S4847	Faropenem Sodium Faropenem sodium是具有口服活性的β-内酰胺抗生素，用于研究治疗肺结核和社区获得性肺炎的试验中。
S4565	Diiodohydroxyquinoline Diiodohydroxyquinoline是一种局部药物，喹啉衍生物，具有抗菌特性。
S4999	Avermectin B1 Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
S9185	Nitidine Chloride Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
S5456	Isobavachalcone Isobavachalcone, a naturally occurring chalcone compound derived from the seeds of Psoralea corylifolia L., has long been used in traditional Chinese medicine as anthelmintic, antibacterial, aphrodisiac, astringent and antiplatelet agent.
S5247	Selamectin Selamectin is a novel macrocyclic lactone of the avermectin class. It paralyses and/or kills a wide range of invertebrate parasites through interference with their chloride channel conductance causing disruption of normal neurotransmission and has adulticidal, ovicidal and larvicidal activity against fleas.

目录号	产品描述	文献引用	实验数据
S2430^New	Azodicarbonamide Azodicarbonamide是第一个已知的通过靶向 nucleocapsid CCHC domains 来抑制 HIV-1 和多种逆转录病毒的核衣壳抑制剂。在标准的基于细胞的抗病毒试验中，Azodicarbonamide抑制HIV-1_RF诱导的CEM-SS细胞病变，EC50为38 µM。
S6689^New	Merimepodib Merimepodib是一种有效、特异性和可逆的inosine monophosphate dehydrogenase(IMPDH)抑制剂，在体外对丙型肝炎病毒(HCV)和多种DNA和RNA病毒具有抗病毒活性。Merimepodib是一种免疫抑制剂。
S6771^New	MAC-545496 MAC-545496是一种纳摩尔浓度的glycopeptide-resistance-associated protein R(GraR)抑制剂，对全长GraR蛋白(Kd≤0.1 nM)具有很强的结合亲和力。 MAC-545496可以逆转耐甲氧西林菌株中的β-内酰胺耐药性，并与CAMP协同作用。 MAC-545496在巨噬细胞中显示出显着的活性，并减弱了苜蓿根瘤菌幼虫感染模型中的金黄色葡萄球菌毒力。
S8932^New	Remdesivir (GS-5734) Remdesivir是腺苷类似物的单磷酰胺酸盐前药，是一种研究性的广谱抗病毒剂，对多种RNA病毒（包括埃博拉病毒和CoV病毒）具有体外活性。
S6676^New	Ebselen Ebselen是HIV-1复制的小分子衣壳抑制剂，在TR-FRET分析中的IC50为46.1 nM。
S6549^New	PBTZ169 PBTZ169是DprE1的不可逆性抑制剂，是一种抗生素。	Cell Death Dis,2019, 10(4):319
S8873^New	Letermovir（AIC246） Letermovir(AIC246, MK-8228)是新型的anti-CMV化合物，靶向病毒末端酶复合体，对DNA聚合酶抑制剂具有抗性的病毒也具有活性。
S5952^New	Baloxavir marboxil Baloxavir marboxil是一种抗病毒药物，是限制内切核酸酶抑制剂。
S2597	Oseltamivir Phosphate Oseltamivir Phosphate 是一种有效的和选择性的，甲型流感和乙型流感病毒复制必需的神经氨酸酶的抑制剂，用于治疗流行性感冒。	Infect Immun,2015, 10.1128/IAI.03118-14	Nystatin, filipin III, and oseltamivir inhibit the labeling of trophozoites by CTXB and GM1 antibodies. (A) Trophozoites were treated with nystatin (27 μM), filipin III (7.6 μM), and oseltamivir (20 μM) for 30 min before labeling with Alexa Fluor-conjugated CTXB antibody (images a to d) and GM1 antibody (images a′ to d′). Myriocin (27 μM), a sphingolipid inhibitor, was used as a negative control (images e and e′). N, nucleus; PM, plasma membrane; F, flagella; VD, ventral disc. Bars, 5 μm. (B and C) Changes in intensity of control and inhibitor-treated trophozoites. For intensity measurements, cells were randomly selected from 10 to 15 fields from 3 to 5 separate experiments. Approximately 50 cells were considered for each condition and were analyzed using Zeiss Zen 2009 confocal software. One-way ANOVAs were performed to evaluate differences (means ± SDs) between the treatment and control groups. Mean intensities from 3 to 5 separate experiments are shown in panels B and C. Statistical significance was calculated using a one-way ANOVA test, followed by the Tukey (B) and Holm-Šídák (C) methods. , P < 0.05; , P < 0.01; **, P < 0.001; NS, not significant.
S2527	Methacycline HCl Methacycline HCl 是一种四环素类抗生素，同时也是表皮间质转换的抑制剂（IC50=5 μM），用于治疗各种感染。	Sci Rep,2018, 8(1):7653
S1677	Chloramphenicol Chloramphenicol是通过抑制蛋白质的合成的抑菌剂。
S2716	Peramivir Trihydrate Peramivir三水合物是抗感染剂Peramivir（RWJ-270201，BCX-1812)的三水合物，这是一种过渡状态模拟和一个强有力的流感病毒神经氨酸酶特异抑制剂,IC50中位数为0.09 nM。	Emerg Microbes Infec,2014, 3, e78 Emerg Microbes Infect,2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of peramivir (C) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S1606	Clotrimazole Clotrimazole是一种合成的抗真菌药物，是imidazole的广谱衍生物。	J Biol Chem,2018, 293(1):333-344
S1956	Miconazole Nitrate Miconazole Nitrate是一种咪唑类抗真菌剂，外用或静脉输液。	Cell Death Dis,2019, 10(6):413 FASEB J,2019, 10.1096/fj.201802603RR
S2557	Terbinafine HCl Terbinafine HCl 通过抑制角鲨烯环氧酶抑制了麦角固醇的合成，用作抗真菌药物。
S2457	Clindamycin HCl Clindamycin HCl 是Clindamycin的水合盐酸盐，是一种半合成的抗生素。
S1611	Cefoperazone Cefoperazone是一种头孢菌素类抗生素，能抑制rMrp2调节的17βG的吸收[³ H]E₂，其IC50是199 μM。
S3007	Zanamivir Zanamivir是神经氨酸酶抑制剂，用于治疗A型流感病毒和B型流感病毒引起的流感的治疗。	Emerg Microbes Infec,2014, 3, e78 Emerg Microbes Infect,2014, 3(11):e78	Dose-response curve of the SH5190, SH5190 R292K and the A(H1N1)pdm09 (2167) viruses in the presence of oseltamivir zanamivir (B) using a chemiluminescent (NA-star) assay. The NA activity of the H7N9 or H1N1 viruses under increasing concentrations (0.03-1000 nM) of the NAIs was determined. Each data point represents the normalized mean ± SEM neuraminidase activity from three replicated wells. The experiments were repeated twice.
S2908	Hygromycin B Hygromycin B是选择性抗生素，有效作用于大多数细菌，真菌，和更高等的真核生物，通过干扰易位，抑制蛋白合成，造成70S核糖体的错译。	Mol Pharmacol,2019, 96(1):13-25
S1854	Bifonazole Bifonazole 是一种抗真菌剂和前列腺芳香化酶抑制剂，IC50为1.6 μM。	Nature,2018, 560(7718):372-376	Percentage of MBP+ oligodendrocytes generated from OPCs following treatment with azoles (c). n ≥ 4 wells per condition.
S1876	Valaciclovir HCl Valaciclovir HCl 是一种抗病毒药，用于治疗单纯疱疹，带状疱疹，疱疹B。
S1997	Liranaftate Liranaftate 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。
S4042	Nafcillin Sodium Nafcillin sodium可逆的抑制 β-内酰胺酶，K_d为33 mM。
S1791	Bacitracin Zinc Bacitracin是一种抗生素，能够干扰C55-isoprenyl pyrophosphate的去磷酸化，C55-isoprenyl pyrophosphate是一种膜载体分子，参与转运构成肽聚糖细菌细胞壁内膜外部成分。Bacitracin抑制甲硫啡肽中Tyr的裂解，IC50为10 μM。
S2572	Streptomycin sulfate Streptomycin sulfate是Streptomycin的硫酸盐形式，是一种蛋白质合成抑制剂。
S1685	Sulfanilamide Sulfanilamide是细菌酶中二氢喋呤合成的适度竞争性抑制剂，IC50为320 μM。
S8279	Shikonin Shikonin，是一种Pyruvate kinase M2 (PKM2)有效的、特异的抑制剂。它是紫草的主要成分，紫草是一种中草药，具有多种生物活性。在细胞荧光淬灭试验中，Shikonin也是TMEM16A氯离子通道的抑制剂。	Int J Biol Sci,2020, 16(1):147-161 JCI Insight,2019, 4(4) Mol Med Rep,2018, 18(4):3882-3890
S5268	Solithromycin Solithromycin, belonging to the well-known class of macrolide antibiotics that also includes azithromycin, is a potent bacterial protein synthesis inhibitor.
S7550	Erythromycin Cyclocarbonate Erythromycin Cyclocarbonate，红霉素的衍生物，通过结合于50S核糖体抑制细菌蛋白质合成。
S7784	Fumagillin Fumagillin是一种选择性且有效的甲硫氨酸胺基肽酶2(MetAP2)不可逆抑制剂，用作抗生素治疗微孢子虫病。
S3077	Tazobactam Tazobactam是一种 β-内酰胺酶抑制剂，具有抗细菌活性。它还能抑制D类苯唑西林酶OXA-2。它常和piperacillin或其他β-lactam抗生素结合使用，来扩增其抗生谱并增强抗生效应。
S4647	Cefmenoxime hydrochloride Cefmenoxime, 肠杆菌科的有效抑制剂，是一种头孢菌素抗生素，通常用于静脉注射或肌内注射。
S5499	Amantadine Amantadine is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is an M2 inhibitor which blocks the ion channel formed by the M2 protein that spans the viral membrane.
S4602	Acetohydroxamic acid Acetohydroxamic acid是尿素酶抑制剂。在尿液中，它可作为细菌酶尿素酶的拮抗剂。
S9303	Saikosaponin B2 Saikosaponin B2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry.	Phytomedicine,2019, 67:153163
S9018	Luteoloside Luteoloside is a member of the flavonoids family that exhibits several bioactivities including anti-microbial and anti-cancer activities. It is an inhibitor of 3C Protease of Enterovirus 71 with an IC50 value of 0.36 mM.
S9063	Harringtonine Harringtonine is a natural cephalotaxine alkaloid that inhibits protein biosynthesis. It also exhibits antiviral and anticancer activities.
S9064	Trilobatin Trilobatin, a natural flavonoid lipid molecule, is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope and exihibits anti-oxidant and anti-inflammatory effect.
S5704	Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S9070	Isoxanthohumol Isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV).
S4198	Aminothiazole Aminothiazole作为甲状腺抑制剂，具有抗菌活性。
S9072	Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S5927	Proguanil Proguanil是预防性抗疟药。它能抑制疟原虫的二氢叶酸还原酶，阻止嘌呤和嘧啶的合成。
S3710	Fosfomycin calcium Fosfomycin是一种杀菌剂，可通过使UDP-N-acetylglucosamine-3-enolpyruvyltransferase失活而一直细菌细胞壁形成。Fosfomycin可通过甘油磷酸盐转运蛋白进入细胞壁。
S5025	Efinaconazole Efinaconazole是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成，ergosterol是真菌细胞膜的成分之一。
S3667	Imipenem Imipenem acts as an inhibitor of AmpC β-lactamase and is an antibiotic useful for the treatment of a number of bacterial infections.
S4105	Closantel Sodium Closantel Sodium是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S4106	Closantel Closantel是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。
S3732	Avibactam sodium Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor with IC50 values of 8, 80, and 38 nM for TEM-1, P99, and KPC-2 β-lactamases, respectively.
S9341	3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S2348	Rotenone (Barbasco) Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport.	Nat Commun,2019, 10(1):3856
S3028	Geneticin (G418 Sulfate) Geneticin (G418 Sulfate), 一种氨基糖苷类抗生素, 是80 S ribosomes延伸的抑制剂，在原核和真核细胞中均能通过抑制延伸步骤来阻断多肽合成。	Mol Cell,2019, 75(6):1103-1116.e9 Antiviral Res,2019, 174:104678
S7417	Puromycin 2HCl Puromycin 2HCl 是一种氨基核苷抗菌素，其可作为蛋白质合成的抑制剂。	Cell Rep,2020, 30(2):497-509 Cancer Lett,2020, 469:380-389 J Clin Invest,2019, 129(6):2333-2350
S4286	Anidulafungin (LY303366) Anidulafungin (LY303366), 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。	Cell Physiol Biochem,2016, 38(6):2272-84	Effect of Anidulafungin on hemolysis. Arithmetic means ± SEM (n = 8) of the percentage of hemolytic erythrocytes following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Anidulafungin (1.5-6 μg/ml). ***(p<0.001) indicates significant difference from the absence of Anidulafungin (ANOVA).
S4854	Bedaquiline fumarate Bedaquiline fumarate, an oral diarylquinoline, is a bactericidal antimycobacterial drug. It is a proton-translocating ATP synthetase inhibitor.
S1958	Sulbactam Sulbactam 是β-内酰胺酶抑制剂，IC50为0.8 μM。
S4564	Diethylcarbamazine citrate Diethylcarbamazine citrate是丝虫微丝蚴中花生四烯酸代谢的抑制剂，对几种寄生虫高度特异，不含任何有毒金属元素。

目录号	产品描述	文献引用	实验数据
S1373	Daptomycin Daptomycin是一种新型抗生素，在体外对革兰氏阳性菌具有快速的杀菌活性。	Biochemistry, 2018, 57(38):5629-5639 Biochem Biophys Res Commun, 2018, 503(3):2033-2039 Front Microbiol, 2018, 9:1175	Same experiment as in Figure 2 with fluorescent daptomycin shown as confocal images. A 7/3 DOPC/DOPG GUV (including 1% Rh-PE) was introduced at time zero into a solution containing 1 uM daptomycin with 0.5 uM BODIPY-daptomycin and 1 mM Ca2+. To show colocalization of lipid and peptide in aggregates, confocal images were taken: red for RH-PE and green for BODIPY-daptomycin. As the protrusion length decreased, aggregates appeared on the GUV surface containing both lipid and peptide. The scale bar is 10 um.
S1408	Linezolid Linezolid 是一种合成的抗生素，用于治疗严重感染。	J Mol Cell Biol, 2019, pii: mjz020 PLoS One, 2019, 14(10):e0222970 Front Microbiol, 2018, 9:1175
S1097	BTZ043 Racemate BTZ043 Racemate是一种decaprenylphosphoryl-β-D-ribose 2’-epimerase的抑制剂，是一个可以杀死结核杆菌的新的抗分支杆菌的药物。	Biochem Pharmacol, 2019, 162:41-54 Blood Adv, 2019, 3(5):797-812
S1517	Natamycin Natamycin 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。
S1403	Tigecycline Tigecycline 是一种甘氨酰环素类抗生素。	BMC Infect Dis, 2017, 17(1):197 Biochem J, 2016, 473(1):99-107 Nat Med, 2015, 21(2):178-84	CHX blocked Pim-1 AUG isoform translocation from the cytosol to mitochondria and led to reduced pBADS112. Cox-2 was examined to assess the effect of tigecycline on mitochondrial translation. Cy-Cox-2: cytoplasmic Cox-2; Mt-Cox-2: mitochondrial Cox-2.
S6761^New	Dalfopristin Dalfopristin is a semi-synthetic analogue of ostreogyrcin A, Quinupristin/dalfopristin is a new combination streptogramin product with a selective spectrum of antibacterial activity, mainly against gram-positive aerobic bacteria.
S9466^New	Methenamine Hippurate Methenamine Hippurate是methenamine的马草酸盐形式，是一种前药和惰性弱碱，在酸性尿液中会水解成甲醛。Methenamine Hippurate是Hiprex药物的成分，具有抗菌活性。
S4393^New	Cephapirin Sodium Cephapirin Sodium是cephapirin的钠盐形式，是一种半合成的第一代头孢菌素抗生素，对革兰氏阴性细菌和革兰氏阳性细菌都有效。
S4404^New	Pasiniazid Pasiniazid，由isoniazid和4-aminosalicylic acid组成，用于治疗肺结核患者。
S6729^New	Besifovir Besifovir是新型有效的无环核苷膦酸酯，用于治疗HBV感染。
S4421^New	Josamycin Josamycin是一种来源于那波链霉菌的大环内脂类抗菌素，对一系列的病原体具有广泛的抗菌活性。
S6582^New	Ozenoxacin Ozenoxacin是一种喹诺酮药物，用于治疗脓疱病。
S8871^New	Omadacycline tosylate Omadacycline是氨甲环素类抗生素，对革兰氏阳性和阴性的需氧菌以及一些厌氧菌具有抗菌活性。
S6562^New	KKL-35 KKL-35抑制trans-translation tagging reaction，IC50为0.9 μM。它具有广谱抗生素活性。
S6444^New	Triclocarban Triclocarban是一种常用于个人护理用品中的抗细菌试剂。
S6451^New	Salifungin Salifungin (Bromochlorosalicylanilide)是一种抗真菌剂，在某些个体中可能导致过敏性接触性皮炎。
S6442^New	Chlorphenesin Chlorphenesin是一种合成的防腐剂，被用于护肤品中，是一种化妆品抗微生物剂。
S6464^New	Ftaxilide Ftaxilide是一种新型的抗痨药。
S6459^New	Nifurtimox Nifurtimox是一种抗原虫剂。
S6467^New	Fosfluconazole Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物，用于治疗和组织表面的和系统性真菌感染。
S6461^New	Permethrin Permethrin是一种合成的I型拟除虫菊酯、具有神经毒性的杀虫剂。
S6423^New	Tildipirosin Tildipirosin是一种半合成的大环内脂类抗菌素。	Nat Cell Biol, 2017, 19(10):1274-1285
S6411^New	Nimorazole Nimorazole是一种水溶性的硝基咪唑化合物，具有抗细菌和潜在的放射增敏作用。
S5944^New	Butenafine Butenafine是合成的苄胺抗真菌剂。
S6288^New	Chlorhexidine diacetate Chlorhexidine diacetate是一种消毒剂和局部抗感染剂，也用于漱口水中防止口腔菌斑。
S6408^New	Hexetidine Hexetidine是一种抗细菌和抗真菌剂，具有局部麻醉、止血、除臭、预防牙菌斑作用。
S6235^New	Sodium dehydroacetate Sodium dehydroacetate是无水醋酸的钠盐形式。无水醋酸是一种杀菌剂，通常被用作食品防腐剂。
S1878	Ganciclovir Ganciclovir 是一种抗病毒药，作用于猫科动物1型疱疹病毒，无细胞试验中IC50为5.2 μM。	PLoS One, 2019, 14(6):e0218471 Cell Stem Cell, 2017, 20(3):407-414.e4 Sci Rep, 2017, 7:43349	Effect of ganciclovir on viral DNA accumulation (A,B) and induction of TGF-β1 production after human cytomegalovirus infection in human trabecular meshwork cells (C). Cells were harvested at 5 day post-infection at a high multiplicity of infection (MOI 1) under the treatment with different concentrations of ganciclovir (GAN). Treatment with 10 μmol of ganciclovir significantly decreased the viral DNA accumulation (p < 0.001) (A,B). However, treatment with ganciclovir did not affect the TGF-β production using a TGF-β1 luciferase bioassay. Results are expressed as the mean +/− standard deviation of three different experiments.
S2504	Ribavirin Ribavirin 是一种抗病毒剂，用于治疗重症RSV感染，丙型肝炎病毒感染和其他病毒感染。	Nat Immunol, 2019, 20(12):1681-1691 Phytomedicine, 2018, 42:258-267 Neuron, 2017, 96(6):1290-1302	(E) Left panel, Western blot showed that 20 μM Ribavirin effectively inhibits elevated Sox2 expression in irradiated SW1990 cells. Right panel, qPCR analysis showed that Sox2 mRNA level in irradiated SW1990 cells at 48 hours was lower than that in non-irradiated SW1990 cells, *p < 0.05. (F) Left panel, Western blot showed 20 μM Ribavirin inhibits elevated Sox2 expression in irradiated BxPc-3 cells. Right panel, qPCR analysis showed that there is no significant fluctuation of Sox2 mRNA in irradiated BxPc-3 cells and Ribavirin did not influence sox2 mRNA level in irradiated BxPc-3 cells.
S1807	Aciclovir Acyclovir 是一种合成的核苷类似物，有效作用于疱疹病毒。	Nat Immunol, 2019, 20(12):1681-1691 Sci Adv, 2019, 5(8):eaax0780 Oncol Rep, 2017, 37(4):2109-2120	(A) HONE1 and (B) HK1-EBV cells were treated with TPA (40 ng/ml) and SB (3 mM) for EBV induction. After 3 h, uninduced and induced HONE1 and HK1-EBV cells were treated with the vehicle control (0.006% DMSO) or indicated concentrations of berberine for 48 h. Subsequently, the culture medium was harvested for quantitative-PCR analysis with EBNA1 primers. Each sample was normalized to the amount of the GAPDH gene; *p<0.05, compared with the control group.
S1374	Doripenem Hydrate Doripenem Hydrate 是一种超广谱的，注射用的抗生素。	ACS Chem Biol, 2018, 13(8):2020-2026
S1381	Meropenem Meropenem是一种超广谱的，注射用的抗生素。
S1162	Pretomanid (PA-824) PA-824是一种抗肺结核药，作用于tuberculosis，MIC为<1 μg/mL。Phase 2。
S1934	Nystatin (Fungicidin) Nystatin (Fungicidin) 是一种多烯类抗真菌剂，常常被用作oropharyngeal candidosis的局部治疗剂。	Fish Shellfish Immunol, 2019, 84:138-147 International Journal of Peptide Research and Therapeutics, 2015, 10.1007/s10989-014-9440-x
S1741	Rifabutin Rifabutin 是一种半合成的Ansamycin 抗生素，具有有效的抗分枝杆菌特性。
S1370	Biapenem Biapenem 是一种碳青霉烯类抗生素，抑制了革兰氏阳性菌以及革兰氏阴性菌的活性。
S1351	Ivermectin Ivermectin是一种chloride channel激活剂，用作广谱抗寄生虫药。	Cell Death Dis, 2019, 10(2):118 Mol Cell, 2017, 68(2):323-335
S1371	Cefoselis Sulfate Cefoselis sulfate 是一种抗生素。
S2159	Tebipenem Pivoxil Tebipenem pivoxil是一种新型口服的 Carbapenem抗生素，用于治疗鼻咽喉及呼吸道感染。
S1636	Amphotericin B Amphotericin B（AMB）是两亲多烯抗生素，使含有麦角固醇-膜具有渗透性。
S1282	Artemisinin Artemisinin青蒿素用于治疗耐多药的恶性疟疾菌株。	Biomed Pharmacother, 2019, 117:109181
S1399	Teicoplanin Teicoplanin是一种预防用的抗生素。
S2468	Fenbendazole Fenbendazole 是一种广谱苯并咪唑类驱虫药，作用于胃肠道寄生虫，IC50为0.01 μg/ml。
S1505	Aztreonam Aztreonam 是一种合成的单环β-内酰胺类抗生素。	Expert Opinion on Orphan Drugs, 2013, 1(7):549-556
S1725	Terbinafine Terbinafine 用于治疗真菌感染，可以杀死真菌或防止其生长。	Eur J Pharm Sci, 2019, 136:104945 BMC Microbiol, 2018, 18(1):203
S2510	Spectinomycin 2HCl Spectinomycin 2HCl是由Streptomyces spectabilis中制备的一种新型的肠道外抗生素。
S1768	Cefditoren Pivoxil Cefditoren pivoxil 是一种广谱的抗生素，用于治疗格兰仕阳性菌和阴性菌感染。
S1450	Nanchangmycin Nanchangmycin是一种聚醚抗生素，与Dianemycin结构相似，非常有效地防治广谱的有害线虫和昆虫，而对哺乳动物和植物没有作用效果。	Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 32(5):686-701 Food Addit Contam Part A Chem Anal Control Expo Risk Assess, 2015, 10.1080/19440049.2015.1008588
S1839	Chloroxine Chloroxine是一种人工合成的抗菌化合物，加入洗发液中，有效治疗头皮屑和脂溢性皮炎。
S2264	Artemether Artemether 是一种抗疟药，用于治疗恶性疟疾的耐药菌株。	PLoS Negl Trop Dis, 2015, 9(3):e0003593	Schistosomicidal effects of PZQ, ART(Artemether) and OXA on 14-day schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
S1666	Flucytosine Flucytosine是氟嘧啶类似物, 是抗菌药，作用于人白色念珠菌（C. albicans）时 IC50 为0.12 μg/mL。
S1998	D-Cycloserine D-Cycloserine是氨基酸D-丙氨酸的类似物。
S2479	Lincomycin HCl Lincomycin HCl 是Lincomycin的一水盐, 是Lincolnensis链霉菌属的成员生长所产生的物质。
S1605	Cefdinir Cefdinir 是一种杀菌抗生素。
S3073	Caspofungin Acetate Caspofungin Acetate是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。	J Microbiol Immunol Infect, 2018, 10.1016/j.jmii.2018.04.002 Antimicrob Agents Chemother, 2017, 61(5) Antimicrobial Agents and Chemotherapy, 2016, 10.1128/AAC.02921-15
S2528	Ciclopirox Ciclopirox 是一种合成的抗真菌药物。
S2152	Sitafloxacin Hydrate Sitafloxacin Hydrate是新一代口服的广谱喹诺酮类抗生素。	mSphere, 2018, 3(5) Interact Cardiovasc Thorac Surg, 2018, 10.1093/icvts/ivy209
S1502	Cephalexin Cephalexin是可以治疗许多细菌感染的抗生素。	Clin Cancer Res, 2018, 24(3):659-673 Theranostics, 2017, 7(7):2092-2107 Blood Cancer J, 2017, 10.1038/bcj.2017.61
S1835	Azithromycin Azithromycin是一种抑制蛋白合成的抗生素，用于细菌感染的治疗。	J Med Chem, 2018, 61(9):4189-4202
S1773	Oxytetracycline (Terramycin) Oxytetracycline(Terramycin) 是第二个被发现的广谱四环素类抗生素。	Sci Rep, 2018, 8(1):7653 Front Microbiol, 2016, 7: 1765	Effect of FDA approved drugs on EBOV transfected donor and recipient immune cells. (A) Varying concentrations of Cambinol and Esomepraole (1 nM, 1 μM, 10 μM), Oxytetracycline (1 nM, 10 nM, 10 μM), and DMSO (0.00001, 0.0001, 0.001%) treatments were administered to VP40-transfected 293T cells, followed by incubation for 3 days. Supernatant was centrifuged to remove cellular material and subsequently incubated for 72 h at 4°C with 20 μL of 30% slurry of NT80/82 beads. The NT pellet was washed twice with PBS and resuspended in SDS Laemmli buffer, followed by Western blot analysis for levels of exosomal markers CD63 and Alix. Actin levels were also analyzed. Mid-log phase EVTR2C cells (containing VP40) were treated with either low (0.1 μM), medium (1 μM), or high (10 μM) concentrations of Oxytetracycline and incubated for 5 days along with untreated 293T cells. Cell-free supernatants were harvested, filtered, and used to treat CEM (B), Jurkat (C), and U937 (D) cells. Cells were incubated for 5 days and assayed with CellTiter-Glo for viability. Statistical significance was determined using two-tailed student’s t-test with all groups compared to the untreated 293T cell control groups. RLU, Relative Luminescent Units. ∗p < 0.05, ∗∗∗p < 0.001.
S1637	Docosanol Docosanol是一种饱和脂肪酸，在化妆品领域，作为一种润肤剂，乳化剂，和增稠剂，也是营养补充剂，抑制病毒产生，ED50为1.7 mg/ml。
S2535	Econazole nitrate Econazole nitrate 是一种咪唑类抗真菌药物。
S2568	Neomycin sulfate Neomycin sulfate属于氨基糖苷类抗生素。
S1777	Ethionamide Ethionamide是一种抗生素，用于治疗肺结核。
S1635	Erythromycin Erythromycin是一种大环内酯类抗生素，具有与青霉素类似的或略宽于青霉素的抗菌谱(IC50为1.5 μg/ml)。	J Med Chem, 2018, 61(9):4189-4202
S2420	Aloperine Aloperine是提取自苦参植物，如Sophora alopecuroides L的生物碱，具有抗炎，抗菌，抗病毒,和抗肿瘤的特性。	PeerJ, 2019, 7:e7652 Onco Targets Ther, 2018, 11:2735-2743
S4226	Minocycline HCl Minocycline HCl 是脂溶性的最活跃的四环素类抗生素，结合到30S核糖体亚基，抑制tRNA结合到核糖体mRNA复合物，干扰蛋白质合成。	J Neurosci, 2020, 40(2):297-310 Brain Behav Immun, 2019, S0889-1591(19)30622-1 J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S2486	Moroxydine HCl Moroxydine HCl 是一种合成的抗病毒化合物，属于杂环双胍系列。
S1644	Nitrofural Nitrofural 是外用的抗感染剂，IC50为22.83±1.2 μM，作用于大鼠，LD50为590 mg/kg。
S3079	Atovaquone Atovaquone 用于治疗或预防肺孢子菌肺炎，弓形虫病, 疟疾和巴贝西虫。	Sci Transl Med, 2015, 7(290):290ra89
S4050	Valganciclovir HCl Valganciclovir HCl是一种ganciclovir 的前体药物，具有抗病毒活性，用于治疗巨细胞病毒感染。	Transl Res, 2016, 177:113-126
S4052	Netilmicin Sulfate Netilmicin Sulfate 是一种氨基糖苷类抗生素家族成员。	J Cancer Res Clin Oncol, 2019, 145(6):1495-1507
S4082	Spiramycin Spiramycin是16元环大环内酯（抗生素）。
S2565	Amoxicillin Sodium Amoxicillin Sodium是一种中等谱，溶菌，β-内酰胺类抗生素。	Toxicol Appl Pharmacol, 2015, 285(1):51-60
S2544	Cefprozil hydrate Cefprozil hydrate 是第二代头孢菌素类抗生素。
S2563	Oxacillin sodium monohydrate Oxacillin sodium monohydrate是一种抗菌剂，是一种窄谱，青霉素类的β-内酰胺类抗生素。
S3129	Trimethoprim Trimethoprim 是一种抑制细菌的抗生素，主要用于预防和治疗尿路感染。
S2028	Diclazuril Diclazuril 是一种抗球虫药。
S3161	Sertaconazole nitrate Sertaconazole nitrate是一种外用广谱抗真菌药，是用来治疗表面皮肤和粘膜感染的辅助用药
S1499	Cefaclor Cefaclor是一种头孢菌素类抗生素。
S1915	Sulfamethoxazole Sulfamethoxazole 是磺胺类抑制细菌的抗生素，IC50为2.7 μM。
S2120	Arbidol HCl Arbidol HCl是一种抗病毒药，用于治疗流感病毒感染。
S2467	Famciclovir Famciclovir 是一种鸟嘌呤类似物抗病毒药物，用于治疗各种疱疹病毒感染。
S2031	Fenticonazole Nitrate Fenticonazole Nitrate 是一种唑类抗真菌药物。
S2574	Tetracycline HCl Tetracycline HCl是Tetracycline的盐酸盐，是一种广谱的聚酮类抗生素。	Sci Rep, 2018, 8(1):7653
S2575	Vancomycin HCl Vancomycin HCl 是Vancomycin的盐酸盐，是一种窄谱的糖肽类抗菌剂。
S1851	Oxibendazole Oxibendazole是一种广谱驱虫药。	Oncol Lett, 2018, 15(2):2218-2226
S2501	Pyrantel Pamoate Pyrantel pamoate是一种广谱驱虫剂，用于治疗一些寄生虫感染。
S4030	Gentamicin Sulfate Gentamycin Sulfate是一种广谱的氨基糖苷类抗生素，用于细胞培养，抑制蛋白合成。
S2514	Tobramycin Tobramycin 是一种氨基糖苷类抗生素，IC50为9.7 μM。
S1762	Pyrazinamide Pyrazinamide 是一种治疗肺结核的药物。
S1676	Amorolfine HCl Amorolfine HCl是一种抗真菌药物。	Cell Chem Biol, 2019, 26(4):593-599 Nature, 2018, 560(7718):372-376	b, GC–MS-based quantification of three metabolite levels in human glioma cells (GBM528) treated for 24 h with the indicated small molecules at the following concentrations: tamoxifen, 100 nM; clemastine, 2 μM; ifenprodil, 2 μM; ketoconazole, 2.5 μM; amorolfine, 100 nM. Left, lanosterol; centre, zymostenol; right, 14-dehydrozymostenol. n = 2 wells per condition.
S4075	Zinc Pyrithione Zinc Pyrithione是一种抗真菌和抗细菌药物，可以通过阻断质子泵破坏膜转运。	Biol Reprod, 2019, 100(2):468-478 Cell Syst, 2017, 4(6-:600-610
S2530	7-Aminocephalosporanic acid 7-Aminocephalosporanic acid 是一种中间体，用于合成头孢菌素类抗生素。
S2536	Miconazole Miconazole 是一种咪唑类抗真菌药物。
S2543	Ceftiofur HCl Ceftiofur HCl 是Ceftiofur的盐酸盐，是一种广谱头孢菌素。
S1691	Praziquantel Praziquantel是一种驱虫药，有效作用于扁形虫。	PLoS Negl Trop Dis, 2015, 9(3):e0003593	Schistosomicidal effects of PZQ, ART and OXA on 14-day-schistosomula. Magnification of the in vitro-cultured schistosomula treated with PZQ, ART, and OXA at 10 μM. Drugs were added at day 14 and schistosomula were analyzed at day 21 (late treatment). 0.1% DMSO in medium (solvent of the drugs; used as negative control) had no effect on schistosomula development.
S4237	Primaquine Diphosphate Primaquine Diphosphate是一种临床有效的阻断传播的抗疟疾药，对人类疟疾的的配子体具有明显的抵抗活性。	Cell Syst, 2019, 8(2):97-108
S1964	Rimantadine Rimantadine 是一种抗流感病毒药物，作用于T. brucei，IC50为7 μM。
S1883	Idoxuridine Idoxuridine 是一种抗病毒药，作用一猫疱疹病毒1型，IC50为4.3 μM。
S3162	Tylosin tartrate Tylosin tartrate是一种大环内酯类抗菌素，用于控制家禽的支原体病。
S1916	Sulfisoxazole Sulfisoxazole 是一种磺胺类抗菌药，具有一个恶唑取代基。
S1770	Sulfadiazine Sulfadiazine 是一种磺胺类抗生素。
S3195	Azlocillin sodium salt Azlocillin sodium salt是一种酰基氨苄青霉素，具有广谱抗菌作用。
S4004	Ethambutol 2HCl Ethambutol是一种抗分枝杆菌抑菌剂, 通过抑制阿拉伯糖基转移酶来干扰细胞壁形成。	Molecules, 2019, 25(1)
S2469	Fleroxacin Fleroxacin 是一种新型广谱喹诺酮类。
S2551	Sulbactam sodium Sulbactam sodium 是不可逆的β-内酰胺酶抑制剂。
S3116	Sulfathiazole Sulfathiazole是一种有机硫化合物，已被用来作为一种短效的磺胺类药物。
S1910	Tioconazole Tioconazole是一种抗真菌药物，IC50为1.7 μM。	Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S2506	Roxithromycin Roxithromycin 是一种半合成的大环内酯类抗生素，用于治疗呼吸道，泌尿及软组织感染。	J Med Chem, 2018, 61(9):4189-4202
S2048	Clindamycin Phosphate Clindamycin Phosphate是一种林可酰胺类抗生素，作用于 Plasmodium falciparum，IC50为12 nM。
S3055	Besifloxacin HCl Besifloxacin HCl是一种第四代氟喹诺酮类抗生素。
S4120	Sulconazole Nitrate Sulconazole Nitrate 是一种咪唑衍生物，具有广谱抗真菌活性。
S2511	Sulfadoxine Sulfadoxine是一种超长效磺胺类药物，作用于P. Vivax，IC50为249 μg/ml。
S3067	Chlorhexidine 2HCl Chlorhexidine HCl是一种防腐剂，可以有效抵抗大多数革兰氏阴性和阳性有机体。
S3059	Enrofloxacin Enrofloxacin是一种氟喹诺酮类抗生素。
S4141	Dinitolmide Dinitolmide 是一种广谱抗球虫的药物。
S1977	Sarafloxacin HCl Sarafloxacin HCl是Sarafloxacin的盐酸盐形式，是一种喹诺酮类抗生素IC50为0.96 μg/L。
S4146	Bacitracin Bacitracin是由Bacillus subtilis var生物体产生的相关环状多肽组成的混合物，通过干扰细胞壁肽聚糖的合成，从而破坏革兰氏阳性和革兰氏阴性细菌。	Chem Res Toxicol, 2017, 30(10):1804-1814

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