Hydroxychloroquine (HCQ) Sulfate
别名: NSC 4375 中文名称：硫酸羟氯喹
Hydroxychloroquine (HCQ) Sulfate是一种抗疟疾药，用于治疗系统性红斑狼疮，类风湿关节炎等自身免疫病，炎症以及皮肤病。它也是autophagy和toll-like receptor (TLR) 7/9的抑制剂。
Hydroxychloroquine (HCQ) Sulfate Chemical Structure
CAS: 747-36-4
客户使用Selleck的Hydroxychloroquine (HCQ) Sulfate发表文献91篇：
产品质控
Autophagy抑制剂选择性比较
细胞实验数据示例
| 细胞系 | 实验类型 | 给药浓度 | 孵育时间 | 活性描述 | 文献信息 |
|---|---|---|---|---|---|
| Function assay | NXHseYFzUEWNLVLseYUh[2WubIO= | M13JVGFvfGGpb37pd5Qh[WO2aY\peJkh[XRiaIXtZY4hXEyUOTDlfJBz\XO|ZXSgbY4hUEWNLVLseYUh[2WubIOgZZN{\XO|ZXSgZZMhemWmdXP0bY9vKGmwIFPwS2IucW6mdXPl[EBPTi2tYYDwZWIhdGW4ZXzzJIFnfGW{IEK0JIhzeyCkeTDzdIVkfHKxcHjveI9u\XS{aXOgZY5idHm|aYOsJGlEPTBiPTCwMlEyKM7:TT6= | M1nEWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMkmyPFk3Lz5|MEK5Nlg6PjxxYU6= | ||
| Antiviral assay | NFnje|dX\XKxIFW2JINmdGy| | MXW0PEBp | NYq3WHFHUUN3MDDmc5Ih[W62aY\pdoFtKGGldHn2bZR6KGGpYXnud5QhW0GUUz3Dc3YuOiCrbjD0bIUhXmW{bzDFOkBk\WyuIHzpcoUh[XRiNEigbEBjgSCrbX31co9ndHWxcnXzZ4Vv[2VvYnHz[YQh[XO|YYmgLIRmfGWldHnu[{B1cGVidnnyZYwhVlBicILveIVqdiCrbjD0bIUhdnWlbHX1d{Bw\iC2aHWgWoVzdyCHNjDj[YxteylwLDDJR|UxKD1iMD62O|YxQCEQvF2u | M17zRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzN{M{WzPFU6Lz5|MkO1N|g2QTxxYU6= | |
| Function assay | NWj3XHZFUEWNLVLseYUh[2WubIO= | MlOyRY51[WexbnnzeEBi[3Srdnn0fUBifCCqdX3hckBVVFJ5IHX4dJJme3OnZDDpckBJTUtvQnz1[UBk\WyuczDhd5Nme3OnZDDhd{Bz\WS3Y4Tpc44hcW5iQ1yyOlQucW6mdXPl[EBPTi2tYYDwZWIhdGW4ZXzzJIFnfGW{IEK0JIhzeyCkeTDzdIVkfHKxcHjveI9u\XS{aXOgZY5idHm|aYOsJGlEPTBiPTCwMlgh|ryPLh?= | NYL1[pdHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{CyPVI5QTZpPkOwNlkzQDl4PD;hQi=> | ||
| Function assay | MmLzTGVMOjl|IHPlcIx{ | MWPoSXJIKGKrbnTpcoch[XO|YYnzPkBFcXOybHHj[Y1mdnRib3[gX|NJZS2Gb3\leIltcWSnIDi1JI5OKG[rbnHsLUBnem:vIHjFVmchdWWvYoLhcoV{KG:kdHHpcoVlKG[{b32gTGVMOjl|IHPlcIx{NCCNaTC9JFIvPTFzOEmg{txONg>? | NHS2OZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MkO1N|g2QSd-M{KzOVM5PTl:L3G+ | ||
| Antiviral assay | NUflSXc2XmW{bzDFOkBk\Wyucx?= | M3jIdWlEQTBiZn;yJIFvfGm4aYLhcEBi[3Srdnn0fUBi\2GrboP0JHNCWlNvQ3;WMVIhcW5idHjlJHZmem9iRU[gZ4VtdCCuaX7lJIJ6KG2nYYP1dolv\yCrbn\lZ5Rqd3W|II\pdoFtKHSrdHXyJI9nKHO3cHXycoF1\W62IH\yc40h[2:vcH;1coQufHKnYYTl[EBX\XKxIFW2JINmdGy|IHL5JG1m\GmjbjDUbZN{fWViQ4XseJVz\SCLbn\lZ5Rqd3W|IFTvd4UhMFSFSVSpOVAh[nlidHjlJI1mfGixZDDv[kBT\WWmIHHu[EBOfWWwY3isJGlEQTBiPTC1Mlc5KM7:TT6= | M3jKelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzN{M{WzPFU6Lz5|MkO1N|g2QTxxYU6= | ||
| Antiproliferative assay | NH76XlFDgFCFMzDj[Yxtew>? | NGG2XWc4OiCqcoO= | Ml3qRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZYdicW6|dDDoeY1idiCEeGDDN{Bk\WyuczDh[pRmeiB5MjDodpMh[nliU2LCJI1mfGixZDygTWM2OCB;IEOzJO69VS5? | MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ7OUG1O{c,OjV4OUmxOVc9N2F- | |
| qHTS assay | M2n0WmE3PzNiY3XscJM> | Mn7KdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[|ohWHKrbXHyfUB{[3KnZX6g[o9zKEF4N{OgZ4VtdHN? | M333OlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6= | ||
| qHTS assay | NUPLNm1iSlRvM{egZ4VtdHN? | MUDxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhSlRvM{egZ4VtdHN? | NHXMeIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N|UyOzl:L3G+ | ||
| qHTS assay | NHP6VI1UUy2QLV3DJINmdGy| | MXnxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhW0tvTj3NR{Bk\Wyucx?= | MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR|NUGzPUc,Ojl2M{WxN|k9N2F- | ||
| qHTS assay | NXjzS|ZxVkJvRVLjNUBk\Wyucx?= | MVrxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhVkJvRVLjNUBk\Wyucx?= | NIDFeno9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N|UyOzl:L3G+ | ||
| qHTS assay | NUKweZJiVEGQLUWgZ4VtdHN? | MmPJdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[|ohWHKrbXHyfUB{[3KnZX6g[o9zKEyDTj21JINmdGy| | NInaZmE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N|UyOzl:L3G+ | ||
| Antiproliferative assay | MW\BOVQ6KGOnbHzz | Ml;2NlUhfWdxbXy= | NFm2N5IzOCCqcoO= | MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDpckBpfW2jbjDBOVQ6KGOnbHzzJIF1KDJ3IIXnM41tKHWyIITvJFIxKGi{czDifUB5S0WOTHnn[Y5k\SCUVFPBJHNRKGKjc3XkJINmdGy3bHHyJIlueGWmYX7j[UBidmGueYPpdy=> | NXfPUJZ6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1O|A6PzdpPkK4OVcxQTd5PD;hQi=> |
| Antiproliferative assay | NYXZdGxrSTV2OTDj[Yxtew>? | NY\D[otFOjVidXevcYw> | M1XsZVYxKGi{cx?= | MonvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgbY4hcHWvYX6gRVU1QSClZXzsd{BifCB{NTD1[{9udCCjZoTldkA3OCCqcoOgZpkhgEOHTFzp[4Vv[2ViUmTDRUBUWCCkYYPl[EBk\WyudXzhdkBqdXCnZHHuZ4Uh[W6jbInzbZM> | MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDV5MEm3O{c,Ojh3N{C5O|c9N2F- |
| Autophagy assay | MoO2UmNKNUh|MUKyJINmdGy| | NF6xblgzPSC2bzC1NEB2VQ>? | MWm2JIhzew>? | MmG4TY5pcWKrdHnvckBw\iCjdYTvdIhi\3liaX6gbJVu[W5iTlPJMWg{OTJ{IHPlcIx{KGG|c3Xzd4VlKGG|IHnuZ5Jm[XOnIHnuJJB2dmO2YYTlJGxEOyCneIDy[ZN{cW:wIHH0JFI2KHSxIEWwJJVOKGGodHXyJFYhcHK|IHL5JIZtfW:{ZYPj[Y5k\SCvaXPyc5Nkd3CrYzDhcoFtgXOrcx?= | NYLKSG85RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2PVkyPTdpPkK1Olk6OTV5PD;hQi=> |
| Apoptosis assay | NGLTPIVJPDZyIHPlcIx{ | MkjrNlUhfG9iN{WgeW0> | MmnlNlQhcHK| | MlLXTY5lfWO2aX;uJI9nKGGyb4D0c5NqeyCrbjDoeY1idiCKNE[wJINmdGy|IHH0JFI2KHSxIEe1JJVOKGGodHXyJFI1KGi{czDifUBidm6neHnuMXYhe3SjaX7pcocu[mG|ZXSg[oxwfyCleYTvcYV1enl? | NWmzT5FjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2PVkyPTdpPkK1Olk6OTV5PD;hQi=> |
| Autophagy assay | NY\INoNTUDR4MDDj[Yxtew>? | M4\ERVI1KGi{cx?= | MlTKTY5pcWKrdHnvckBw\iCjdYTvdIhi\3liaX6gbJVu[W5iSES2NEBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCOQ{OtNkBt\X[nbDDheEBKSzVyIHHmeIVzKDJ2IHjyd{BjgSCrbX31co9jdG:2IHHuZYx6e2m| | NE\CfFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[5PVE2Pyd-MkW2PVkyPTd:L3G+ | |
| Antiviral assay | NX62fGRXXmW{bzDFOkBk\Wyucx?= | NXzubmd3OiCmYYnz | NHX3TIlCdnSrdnnyZYwh\W[oaXPhZ5kh[WejaX7zeEBUSVKVLVPvWk0zKCi|dILhbY4hSmG4UHH0NUkhcW5iVnXyc{BGPiClZXzsd{Bie3Onc4Pl[EBjgSCrbnjpZol1cW:wIH;mJJZqemGuIGLORUBz\XCuaXPheIlwdiCvZXHzeZJm\CCkeTDSWE1RS1JiYX\0[ZIhOiCmYYnzMEBGSzVyIE2gOE4yPyEQvF2u | MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyxOlkxNyd-Q3jFUWJNRC:jPh?= | |
| Antiviral assay | MXLW[ZJwKEV4IHPlcIx{ | NF3h[Jg{KGSjeYO= | MmPKTWM2OCCmZYTldo1qdmG2aX;uJIF1KE2RSTCwMlAxPCC3c3nu[{BE\WyuVHn0[ZIuKEeubzCoR3RIMSCjc4PhfUwheGW{Zn;ycYVlKDNiZHH5d{Bxd3O2LXnu[oVkfGmxbjDpckBUSVKVLVPvWk0zKGmwZnXjeIVlKF[ncn:gSVYh[2WubIOsJGlEPTBiPTC5MlIyKM7:TT6= | NHv2co89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmwyPjlyLze+R4hGVUKOPD;hQi=> | |
| Antiviral assay | MV;W[ZJwKEV4IHPlcIx{ | NXm1XGJVOyCmYYnz | MYLJR|UxKGSndHXycYlv[XSrb36gZZQhVU:LIECuNFEhfXOrbnegR4VtdFSrdHXyMUBIdG9iKFPUS{kh[XO|YYmsJJBmem[xcn3l[EA{KGSjeYOgdI9{fC2rbn\lZ5Rqd25iaX6gV2FTWy2Fb2[tNkBqdm[nY4Tl[EBX\XKxIFW2JINmdGy|LDDJR|UxKD1iMUGuNVch|ryPLh?= | NWLuO3c1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOTZ7MD:nQmNpTU2ETEyvZV4> | |
| Antiviral assay | NEXR[mNX\XKxIFW2JINmdGy| | NEXa[mkzKGSjeYO= | M1HQbWFvfGm4aYLhcEBm\m[rY3HjfUBi\2GrboP0JHNCWlNvQ3;WMVIhMHO2cnHpckBD[X[SYYSxLUBqdiCYZYLvJGU3KGOnbHzzJIF{e2W|c3XkJIJ6KGmwaHnibZRqd25ib3[geolz[WxiUl7BJJJmeGyrY3H0bY9vKG2nYYP1doVlKGK7IGLUMXBEWiCjZoTldkAzKGSjeYOsJGVEQTBiPTCyOU41QSEQvF2u | M2HJcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFE3QTBxJ{7DbGVOSkx:L3G+ | |
| 点击查看更多细胞系数据 | |||||
生物活性
| 产品描述 | Hydroxychloroquine (HCQ) Sulfate是一种抗疟疾药，用于治疗系统性红斑狼疮，类风湿关节炎等自身免疫病，炎症以及皮肤病。它也是autophagy和toll-like receptor (TLR) 7/9的抑制剂。 | ||
|---|---|---|---|
| 靶点 |
|
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT04731051 | Not yet recruiting | 2019 Novel Coronavirus | King Hussein Cancer Center|Amman Pharmaceutical Industries (API)|Sana Pharmaceutical Industry|ACDIMA Biocenter | October 2022 | Phase 1|Phase 2 |
| NCT05237843 | Not yet recruiting | Recurrent Pregnancy Loss | Ain Shams University | March 1 2022 | Phase 1 |
| NCT05113810 | Recruiting | 2019 Novel Coronavirus | Ministry of Health Jordan|King Hussein Cancer Center|ACDIMA Biocenter|Amman Pharmaceutical Industries|Sana Pharmaceutical Industry | March 20 2022 | Phase 2 |
| NCT04566133 | Recruiting | Bile Duct Cancer|Biliary Cancer|Biliary Tract Neoplasms|Cholangiocarcinoma | National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC) | February 15 2022 | Phase 2 |
| NCT04385264 | Suspended | COVID-19 | Center for Primary Care and Public Health (Unisante) University of Lausanne Switzerland | January 2022 | Phase 2|Phase 3 |
| NCT04523857 | Recruiting | Breast Cancer | Abramson Cancer Center of the University of Pennsylvania | November 1 2021 | Phase 2 |
化学信息&溶解度
| 分子量 | 433.95 | 分子式 | C18H28ClN3O5S |
| CAS号 | 747-36-4 | SDF | Download Hydroxychloroquine (HCQ) Sulfate SDF |
| Smiles | CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O | ||
| 储存条件(自收到货起) | |||
|
体外溶解度 |
Water : 87 mg/mL DMSO : Insoluble ( DMSO吸湿会降低化合物溶解度，请使用新开封DMSO) Ethanol : Insoluble |
摩尔浓度计算器 |
|
体内溶解度 现配现用，请按从左到右的顺序依次添加，澄清后再加入下一溶剂 |
动物体内配方计算器 | ||||
|
点击购买：
|
|||||
实验计算
动物体内配方计算器（澄清溶液）
第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量）
第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系Selleck为您提供正确的澄清溶液配方）
计算结果：
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于μL DMSO溶液（母液浓度mg/mL，注：如该浓度超过该批次药物DMSO溶解度，请先联系Selleck）；
体内配方配制方法：取μL DMSO母液，加入μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入μL ddH2O，混匀澄清。
体内配方配制方法：取μL DMSO母液，加入μL Corn oil，混匀澄清。
注意：1. 首先保证母液是澄清的；
2.一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
技术支持
在订购、运输、储存和使用我们的产品的任何阶段，您遇到的任何问题，均可以通过拨打我们的热线电话400-668-6834，或者技术支持邮箱tech@selleck.cn，直接联系到我们。我们会在24小时内尽快联系您。
如果有其他问题，请给我们留言。
* 必填项
Copyright 2013 Selleck中国. All Rights Reserved.
沪ICP备13045345号-1沪公网安备 31011502012800号