Hydroxychloroquine Sulfate (NSC 4375)

For research use only. Not for use in humans.

目录号:S4430 别名: HCQ 中文名称:羟氯喹

Hydroxychloroquine Sulfate (NSC 4375) Chemical Structure

CAS No. 747-36-4

Hydroxychloroquine Sulfate (NSC 4375, HCQ)是一种抗疟疾药,用于治疗系统性红斑狼疮,类风湿关节炎等自身免疫病,炎症以及皮肤病。它也是autophagytoll-like receptor (TLR) 7/9的抑制剂。

规格 价格 库存 购买数量  
RMB 1215.82 现货
RMB 1764.93 现货
RMB 3248.32 现货
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客户使用Selleck生产的Hydroxychloroquine Sulfate (NSC 4375)发表文献65篇:

产品安全说明书

Autophagy抑制剂选择性比较

生物活性

产品描述 Hydroxychloroquine Sulfate (NSC 4375, HCQ)是一种抗疟疾药,用于治疗系统性红斑狼疮,类风湿关节炎等自身免疫病,炎症以及皮肤病。它也是autophagytoll-like receptor (TLR) 7/9的抑制剂。
靶点
TLR9 [5] Autophagy [1]
体外研究

Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process.HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis[2].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Function assay M3r1VmhGUy2EbIXlJINmdGy| NGDndWtCdnSjZ3;ubZN1KGGldHn2bZR6KGG2IHj1cYFvKFSOUkmg[ZhxemW|c3XkJIlvKEiHSz3CcJVmKGOnbHzzJIF{e2W|c3XkJIF{KHKnZIXjeIlwdiCrbjDDdGdDNWmwZIXj[YQhVkZva3HwdIFDKGyndnXsd{Bi\nSncjCyOEBpenNiYomgd5Bm[3S{b4Doc5RwdWW2cnnjJIFv[Wy7c3nzMEBKSzVyIE2gNE4yOSEQvF2u MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ7Mki5Okc,OzB{OUK4PVY9N2F-
Antiviral assay M{nZTXZmem9iRU[gZ4VtdHN? NGO0fXQ1QCCq NH;hWlZKSzVyIH\vdkBidnSrdnnyZYwh[WO2aY\peJkh[WejaX7zeEBUSVKVLVPvWk0zKGmwIITo[UBX\XKxIFW2JINmdGxibHnu[UBifCB2ODDoJIJ6KGmvbYXuc4ZtfW:{ZYPj[Y5k\S2kYYPl[EBie3OjeTCo[IV1\WO2aX7nJJRp\SC4aYLhcEBPWCCycn;0[YlvKGmwIITo[UBvfWOuZYXzJI9nKHSqZTDW[ZJwKEV4IHPlcIx{MS5uIFnDOVAhRSByLk[3OlA5KM7:TT6= NIC5RlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MkO1N|g2QSd-M{KzOVM5PTl:L3G+
Function assay NVTpeIZZUEWNLVLseYUh[2WubIO= MVLBcpRi\2:waYP0JIFkfGm4aYT5JIF1KGi3bXHuJHRNWjdiZYjwdoV{e2WmIHnuJGhGUy2EbIXlJINmdGy|IHHzd4V{e2WmIHHzJJJm\HWldHnvckBqdiCFTEK2OE1qdmS3Y3XkJG5HNWujcIDhRkBt\X[nbIOgZYZ1\XJiMkSgbJJ{KGK7IIPw[YN1em:yaH;0c41mfHKrYzDhcoFtgXOrczygTWM2OCB;IECuPEDPxE1w M3q1UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMkmyPFk3Lz5|MEK5Nlg6PjxxYU6=
Function assay MUDISWszQTNiY3XscJM> MXLoSXJIKGKrbnTpcoch[XO|YYnzPkBFcXOybHHj[Y1mdnRib3[gX|NJZS2Gb3\leIltcWSnIDi1JI5OKG[rbnHsLUBnem:vIHjFVmchdWWvYoLhcoV{KG:kdHHpcoVlKG[{b32gTGVMOjl|IHPlcIx{NCCNaTC9JFIvPTFzOEmg{txONg>? NI\HTYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MkO1N|g2QSd-M{KzOVM5PTl:L3G+
Antiviral assay MnLwWoVzdyCHNjDj[Yxtew>? MnLOTWM6OCCob4KgZY51cX[rcnHsJIFkfGm4aYT5JIFo[Wmwc4SgV2FTWy2Fb2[tNkBqdiC2aHWgWoVzdyCHNjDj[YxtKGyrbnWgZpkhdWWjc4XybY5oKGmwZnXjeIlwfXNidnnyZYwhfGm2ZYKgc4Yhe3WyZYLuZZRmdnRiZoLvcUBkd22yb4Xu[E11emWjdHXkJHZmem9iRU[gZ4VtdHNiYomgUYVlcWGwIGTpd5N2\SCFdXz0eZJmKEmwZnXjeIlwfXNiRH;z[UApXEOLRDm1NEBjgSC2aHWgcYV1cG:mIH;mJHJm\WRiYX7kJG12\W6laDygTWM6OCB;IEWuO|gh|ryPLh?= NV\WUndWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{KzOVM5PTlpPkOyN|U{QDV7PD;hQi=>
Antiproliferative assay NYmwflFlSniSQ{OgZ4VtdHN? NF[3Nno4OiCqcoO= M1zhVWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIFo[Wmwc4SgbJVu[W5iQojQR|Mh[2WubIOgZYZ1\XJiN{KgbJJ{KGK7IGPSRkBu\XSqb3SsJGlEPTBiPTCzN{DPxE1w MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTZ7OUG1O{c,OjV4OUmxOVc9N2F-
qHTS assay NGP2V49CPjd|IHPlcIx{ MoHPdWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[|ohWHKrbXHyfUB{[3KnZX6g[o9zKEF4N{OgZ4VtdHN? NF76UlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzOVE{QSd-Mkm0N|UyOzl:L3G+
qHTS assay NVHmNpVoSlRvM{egZ4VtdHN? M1jTSZFJXFNib3[gdIVlcWG2cnnjJINidmOncjDj[YxtKGyrbnXzJJRwKGmmZX70bYZ6KG23bITpdIxmKG:ycH;yeJVvcXSrZYOg[o9zKGS{dXegdoVxfXKyb4Ppcoc7KFC{aX3hdpkhe2O{ZXXuJIZweiCEVD2zO{Bk\Wyucx?= MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQTR|NUGzPUc,Ojl2M{WxN|k9N2F-
qHTS assay NH\qcmhUUy2QLV3DJINmdGy| NXn1NZEzeUiWUzDv[kBx\WSrYYTybYMh[2GwY3XyJINmdGxibHnu[ZMhfG9iaXTlcpRq\nlibYXseIlxdGVib4Dwc5J1fW6rdHnld{Bnd3JiZIL1[{Bz\XC3coDvd4lv\zpiUILpcYFzgSC|Y4Ll[Y4h\m:{IGPLMW4uVUNiY3XscJM> MnmxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl2M{WxN|koRjJ7NEO1NVM6RC:jPh?=
qHTS assay Mom2UmIuTUKlMTDj[Yxtew>? MYnxTHRUKG:oIIDl[IlifHKrYzDjZY5k\XJiY3XscEBtcW6nczD0c{Bq\GWwdHnmfUBufWy2aYDs[UBweHCxcoT1col1cWW|IH\vdkBlenWpIILldJVzeG:|aX7nPkBRemmvYYL5JJNkemWnbjDmc5IhVkJvRVLjNUBk\Wyucx?= NX;sUXhqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0N|UyOzlpPkK5OFM2OTN7PD;hQi=>
qHTS assay NEO4TlJNSU5vNTDj[Yxtew>? MlPadWhVWyCxZjDw[YRq[XS{aXOgZ4Fv[2W{IHPlcIwhdGmwZYOgeI8hcWSnboTp[pkhdXWudHnwcIUhd3Cyb4L0eY5qfGmnczDmc5Ih\HK3ZzDy[ZB2enCxc3nu[|ohWHKrbXHyfUB{[3KnZX6g[o9zKEyDTj21JINmdGy| M2C4c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ7NEO1NVM6Lz5{OUSzOVE{QTxxYU6=
Antiproliferative assay NUDON5ZDSTV2OTDj[Yxtew>? MUOyOUB2\y:vbB?= Mm\3NlAhcHK| NH3HNI9CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBqdiCqdX3hckBCPTR7IHPlcIx{KGG2IEK1JJVoN22uIIXwJJRwKDJyIHjyd{BjgSC6Q1XMUIlo\W6lZTDSWGNCKFOSIHLhd4VlKGOnbHz1cIFzKGmvcHXkZY5k\SCjbnHsfZNqew>? NEHNRmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW3NFk4Pyd-Mki1O|A6Pzd:L3G+
Antiproliferative assay M17TO2E2PDliY3XscJM> MlK1NlUhfWdxbXy= NUn5UZMzPjBiaILz MlLDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgbY4hcHWvYX6gRVU1QSClZXzsd{BifCB{NTD1[{9udCCjZoTldkA3OCCqcoOgZpkhgEOHTFzp[4Vv[2ViUmTDRUBUWCCkYYPl[EBk\WyudXzhdkBqdXCnZHHuZ4Uh[W6jbInzbZM> NITZfmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEW3NFk4Pyd-Mki1O|A6Pzd:L3G+
Autophagy assay M1zsb25EUS2KM{GyNkBk\Wyucx?= NIr2[2UzPSC2bzC1NEB2VQ>? MX:2JIhzew>? NXfJbm1kUW6qaXLpeIlwdiCxZjDheZRweGijZ4mgbY4hcHWvYX6gUmNKNUh|MUKyJINmdGy|IHHzd4V{e2WmIHHzJIlv[3KnYYPlJIlvKHC3bnP0ZZRmKEyFMzDlfJBz\XO|aX;uJIF1KDJ3IITvJFUxKHWPIHHmeIVzKDZiaILzJIJ6KG[udX;y[ZNk\W6lZTDtbYNzd3Olb4DpZ{BidmGueYPpdy=> NXGx[2UxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW2PVkyPTdpPkK1Olk6OTV5PD;hQi=>
Apoptosis assay Ml36TFQ3OCClZXzsdy=> NXrvWolZOjVidH:gO|UhfU1? MUCyOEBpenN? MnP4TY5lfWO2aX;uJI9nKGGyb4D0c5NqeyCrbjDoeY1idiCKNE[wJINmdGy|IHH0JFI2KHSxIEe1JJVOKGGodHXyJFI1KGi{czDifUBidm6neHnuMXYhe3SjaX7pcocu[mG|ZXSg[oxwfyCleYTvcYV1enl? NGjnd3Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NU[5PVE2Pyd-MkW2PVkyPTd:L3G+
Autophagy assay NYnpO2t[UDR4MDDj[Yxtew>? NFjESZkzPCCqcoO= MknJTY5pcWKrdHnvckBw\iCjdYTvdIhi\3liaX6gbJVu[W5iSES2NEBk\WyuczDhd5Nme3OnZDDhd{BqdmO{ZXHz[UBqdiCOQ{OtNkBt\X[nbDDheEBKSzVyIHHmeIVzKDJ2IHjyd{BjgSCrbX31co9jdG:2IHHuZYx6e2m| M4LUV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3Nkm5NVU4Lz5{NU[5PVE2PzxxYU6=
Antiviral assay NVHnN5F1XmW{bzDFOkBk\Wyucx?= NYL0RnJxOiCmYYnz M1LsW2FvfGm4aYLhcEBm\m[rY3HjfUBi\2GrboP0JHNCWlNvQ3;WMVIhMHO2cnHpckBD[X[SYYSxLUBqdiCYZYLvJGU3KGOnbHzzJIF{e2W|c3XkJIJ6KGmwaHnibZRqd25ib3[geolz[WxiUl7BJJJmeGyrY3H0bY9vKG2nYYP1doVlKGK7IGLUMXBEWiCjZoTldkAzKGSjeYOsJGVEPTBiPTC0MlE4KM7:TT6= M2\ud|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFE3QTBxJ{7DbGVOSkx:L3G+
Antiviral assay NV7CSWVZXmW{bzDFOkBk\Wyucx?= M1nIUFMh\GG7cx?= MoO2TWM2OCCmZYTldo1qdmG2aX;uJIF1KE2RSTCwMlAxPCC3c3nu[{BE\WyuVHn0[ZIuKEeubzCoR3RIMSCjc4PhfUwheGW{Zn;ycYVlKDNiZHH5d{Bxd3O2LXnu[oVkfGmxbjDpckBUSVKVLVPvWk0zKGmwZnXjeIVlKF[ncn:gSVYh[2WubIOsJGlEPTBiPTC5MlIyKM7:TT6= NYPM[4J5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNOTZ7MD:nQmNpTU2ETEyvZV4>
Antiviral assay Ml7aWoVzdyCHNjDj[Yxtew>? NXe0VlRsOyCmYYnz Mo\2TWM2OCCmZYTldo1qdmG2aX;uJIF1KE2RSTCwMlAyKHW|aX7nJGNmdGyWaYTldk0hT2yxIDjDWGcqKGG|c3H5MEBx\XKob4Lt[YQhOyCmYYnzJJBwe3RvaX7m[YN1cW:wIHnuJHNCWlNvQ3;WMVIhcW6oZXP0[YQhXmW{bzDFOkBk\WyuczygTWM2OCB;IEGxMlE4KM7:TT6= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQlyxOlkxNyd-Q3jFUWJNRC:jPh?=
Antiviral assay M3q4OHZmem9iRU[gZ4VtdHN? MkjONkBl[Xm| MVXBcpRqfmm{YXyg[YZncWOjY4mgZYdicW6|dDDTRXJUNUOxVj2yJEh{fHKjaX6gRoF3WGG2MTmgbY4hXmW{bzDFOkBk\WyuczDhd5Nme3OnZDDifUBqdmirYnn0bY9vKG:oII\pdoFtKFKQQTDy[ZBtcWOjdHnvckBu\WG|dYLl[EBjgSCUVD3QR3Ih[W[2ZYKgNkBl[Xm|LDDFR|kxKD1iMkWuOFkh|ryPLh?= M{izcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFE3QTBxJ{7DbGVOSkx:L3G+

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p62 / LC3-I / LC3-II / GAPDH; 

PubMed: 31268153     


Effects of BC001 and/or HCQ on the expression of Beclin1, LC3 and p62. (C) The expression of p62 and LC3 in BGC823 cells treated with HCQ and/or BC001.

NLRP3 / β-actin; 

PubMed: 31775905     


NLRP3 expression in neutrophils. Neutrophils were pretreated with the indicated concentrations of hydroxychloroquine for 1 h and stimulated with SAA (10 μg/ml) for 24 h. Cellular lysates were analyzed by Western using anti-NLRP3 or anti-β-actin antibodies. Three experiments were performed using different neutrophils, and a representative result is shown.

p-NF-κB / β-actin; 

PubMed: 31775905     


Phosphorylation of NF-κB p65 in SAA-treated neutrophils. Neutrophils were pretreated with the indicated concentrations of hydroxychloroquine for 2 h and stimulated with SAA (10 μg/ml) for 20 min. Cells were lysed and cellular lysates were subjected to Western blot using anti-phosphor-NF-κB and β-actin antibodies. Data are representative of two independent experiments.

NOX2 / β-actin; 

PubMed: 32260307     


Western blot representative for NOX2 protein expression of HUVECs untreated (cont) or treated with 100 ng/mL TNF-α (a) or 20% preeclampsia (PE) sera (b) with or without apocynin (apo, 100 μM) or hydroxychloroquine (HCQ, 1 μg/mL). β-actin was used as a loading control.

31268153 31775905 32260307
IHC
HE staining of spleen tissue; 

PubMed: 29456648     


Hematoxylin and eosin staining of the spleen tissue in each group (magnification, ×400). PDS, prednisone; H-HCQ, high-dose hydroxychloroquine; L-HCQ, low-dose hydroxychloroquine; ART, artemisinin.

29456648
Immunofluorescence
ZO-1; 

PubMed: 32260307     


Immunofluorescent staining of ZO-1 on HUVECs treated with 100 ng/mL recombinant TNF-α or 20% preeclampsia sera for 16–22 h. Representative images from one of six experiments are shown. (A) Control untreated HUVECs, (B) TNF-α 100 ng/mL, (C) TNF-α 100 ng/mL with hydroxychloroquine 1 μg/mL, (D) control HUVECs treated with 20% normal pregnancy sera, (E) 20% preeclampsia sera, and (F) preeclampsia sera with hydroxychloroquine 1 μg/mL. Arrows show the ZO-1 staining on the endothelial cell border.

32260307
体内研究 The treatment of Hydroxychloroquine Sulfate reduces the infarct size in an in vivo rat model of I/R injury and the cardioprotective effect of Hydroxychloroquine is ERK1/2 dependent[3]. In addition, Hydroxychloroquine Sulfate shows an early vascular protective effect. HCQ seems to prevent the occurrence of endothelial dysfunction(ED) in treated animals[4].

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

激酶实验:[2]
- 合并

In vitro kinase assays:

with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. Total and phosphorylated S6 at ser235/236 and ser240/244 are detected by western analysis using phosphospecific antibodies. Note that recombinant GST-tagged S6 (53 kd) is distinguished from endogenous S6 (32 kd) on the western blot.
细胞实验:[2]
- 合并
  • Cell lines: Human RCC cell lines
  • Concentrations: 75 or 100 μM
  • Incubation Time: 48 h
  • Method: All cells are cultured in RPMI with 10% FBS, 1% glutamine, and 1% Pen/Strep. cells are seeded on the appropriated plates overnight and treated with HCQ (75 or 100 μM) for 48 hours.
    (Only for Reference)

溶解度 (25°C)

体外 Water 67 mg/mL (154.39 mM)
DMSO Insoluble
Ethanol Insoluble

* 溶解度检测是由Selleck技术部门检测的,可能会和文献中提供的溶解度有所差异,这是由于生产工艺和批次不同产生的正常现象。请按照顺序依次加入各个纯溶剂。

化学数据

分子量 433.95
化学式

C18H28ClN3O5S

CAS号 747-36-4
储存条件 粉状
溶于溶剂
别名 HCQ

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % ddH2O
计算重置

计算器

摩尔浓度计算器

摩尔浓度计算器

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

摩尔浓度计算公式

  • 质量
    浓度
    体积
    分子量

*在配置溶液时,请务必参考Selleck产品标签上、SDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。

稀释计算器

稀释计算器

用本工具协助配置特定浓度的溶液,使用的计算公式为:

开始浓度 x 开始体积 = 最终浓度 x 最终体积

稀释公式

稀释公式一般简略地表示为: C1V1 = C2V2 ( 输入 输出 )

  • C1
    V1
    C2
    V2

在配置溶液时,请务必参考Selleck产品标签上、SDS / COA(可在Selleck的产品页面获得)批次特异的分子量使用本工具。.

连续稀释计算器方程

  • 连续稀释

  • 计算结果

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
分子量计算器

分子量计算器

通过输入化合物的化学式来计算其分子量:

总分子量:g/mol

注:化学分子式大小写敏感。C10H16N2O2 c10h16n2o2

摩尔浓度计算器

质量 浓度 体积 分子量
计算

临床试验信息

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04007562 Unknown status Drug: Hydroxychloroquine Sulfate LIPIN1 Deficiency Assistance Publique - Hôpitaux de Paris July 2019 --

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Autophagy Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID